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Items: 1 to 50 of 103

1.

Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.

Müller I, Strozyk E, Schindler S, Beissert S, Oo HZ, Sauter T, Lucarelli P, Raeth S, Hausser A, Al Nakouzi N, Fazli L, Gleave ME, Liu H, Simon HU, Walczak H, Green DR, Bartek J, Daugaard M, Kulms D.

Mol Cell. 2020 Jan 13. pii: S1097-2765(19)30953-0. doi: 10.1016/j.molcel.2019.12.023. [Epub ahead of print]

PMID:
31982308
2.

Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients.

Nickels SL, Walter J, Bolognin S, Gérard D, Jaeger C, Qing X, Tisserand J, Jarazo J, Hemmer K, Harms A, Halder R, Lucarelli P, Berger E, Antony PMA, Glaab E, Hankemeier T, Klein C, Sauter T, Sinkkonen L, Schwamborn JC.

Parkinsonism Relat Disord. 2019 Oct;67:48-55. doi: 10.1016/j.parkreldis.2019.09.018. Epub 2019 Sep 19.

3.

Clinical update on head and neck cancer: molecular biology and ongoing challenges.

Alsahafi E, Begg K, Amelio I, Raulf N, Lucarelli P, Sauter T, Tavassoli M.

Cell Death Dis. 2019 Jul 15;10(8):540. doi: 10.1038/s41419-019-1769-9. Review.

4.

Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma.

Del Mistro G, Lucarelli P, Müller I, De Landtsheer S, Zinoveva A, Hutt M, Siegemund M, Kontermann RE, Beissert S, Sauter T, Kulms D.

NPJ Syst Biol Appl. 2018 Nov 5;4:39. doi: 10.1038/s41540-018-0075-y. eCollection 2018.

5.

Stroma-induced phenotypic plasticity offers phenotype-specific targeting to improve melanoma treatment.

Seip K, Jørgensen K, Haselager MV, Albrecht M, Haugen MH, Egeland EV, Lucarelli P, Engebraaten O, Sauter T, Mælandsmo GM, Prasmickaite L.

Cancer Lett. 2018 Dec 28;439:1-13. doi: 10.1016/j.canlet.2018.09.023. Epub 2018 Sep 18.

PMID:
30240588
6.

Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers.

Raulf N, Lucarelli P, Thavaraj S, Brown S, Vicencio JM, Sauter T, Tavassoli M.

Eur J Cancer. 2018 Oct;102:52-68. doi: 10.1016/j.ejca.2018.07.123. Epub 2018 Aug 21.

PMID:
30142511
7.

Using Regularization to Infer Cell Line Specificity in Logical Network Models of Signaling Pathways.

De Landtsheer S, Lucarelli P, Sauter T.

Front Physiol. 2018 May 22;9:550. doi: 10.3389/fphys.2018.00550. eCollection 2018.

8.

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression.

Lucarelli P, Schilling M, Kreutz C, Vlasov A, Boehm ME, Iwamoto N, Steiert B, Lattermann S, Wäsch M, Stepath M, Matter MS, Heikenwälder M, Hoffmann K, Deharde D, Damm G, Seehofer D, Muciek M, Gretz N, Lehmann WD, Timmer J, Klingmüller U.

Cell Syst. 2018 Jan 24;6(1):75-89.e11. doi: 10.1016/j.cels.2017.11.010. Epub 2017 Dec 13.

9.

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.

Sobotta S, Raue A, Huang X, Vanlier J, Jünger A, Bohl S, Albrecht U, Hahnel MJ, Wolf S, Mueller NS, D'Alessandro LA, Mueller-Bohl S, Boehm ME, Lucarelli P, Bonefas S, Damm G, Seehofer D, Lehmann WD, Rose-John S, van der Hoeven F, Gretz N, Theis FJ, Ehlting C, Bode JG, Timmer J, Schilling M, Klingmüller U.

Front Physiol. 2017 Oct 9;8:775. doi: 10.3389/fphys.2017.00775. eCollection 2017.

10.

FALCON: a toolbox for the fast contextualization of logical networks.

De Landtsheer S, Trairatphisan P, Lucarelli P, Sauter T.

Bioinformatics. 2017 Nov 1;33(21):3431-3436. doi: 10.1093/bioinformatics/btx380.

11.

Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.

Marwitz S, Depner S, Dvornikov D, Merkle R, Szczygieł M, Müller-Decker K, Lucarelli P, Wäsch M, Mairbäurl H, Rabe KF, Kugler C, Vollmer E, Reck M, Scheufele S, Kröger M, Ammerpohl O, Siebert R, Goldmann T, Klingmüller U.

Cancer Res. 2016 Jul 1;76(13):3785-801. doi: 10.1158/0008-5472.CAN-15-1326. Epub 2016 May 17.

12.

Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation.

Iwamoto N, D'Alessandro LA, Depner S, Hahn B, Kramer BA, Lucarelli P, Vlasov A, Stepath M, Böhm ME, Deharde D, Damm G, Seehofer D, Lehmann WD, Klingmüller U, Schilling M.

Sci Signal. 2016 Feb 2;9(413):ra13. doi: 10.1126/scisignal.aab1967.

PMID:
26838549
13.

Drain After Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis. A Pilot Randomized Study.

Lucarelli P, Picchio M, Martellucci J, De Angelis F, di Filippo A, Stipa F, Spaziani E.

Indian J Surg. 2015 Dec;77(Suppl 2):288-92. doi: 10.1007/s12262-012-0797-9. Epub 2012 Dec 18.

14.

Antibiotic prophylaxis in elective laparoscopic cholecystectomy is useless. A prospective multicenter study.

Spaziani E, Picchio M, Di Filippo A, Greco E, Cerioli A, Maragoni M, Faccì G, Lucarelli P, Marino G, Stagnitti F, Narilli P.

Ann Ital Chir. 2015 May-Jun;86(3):228-33.

PMID:
25543880
15.

Meta-analysis of drainage versus no drainage after laparoscopic cholecystectomy.

Picchio M, Lucarelli P, Di Filippo A, De Angelis F, Stipa F, Spaziani E.

JSLS. 2014 Oct-Dec;18(4). pii: e2014.00242. doi: 10.4293/JSLS.2014.00242. Review.

16.

Transanal haemorrhoidal dearterialisation with mucopexy versus stapler haemorrhoidopexy: a randomised trial with long-term follow-up.

Lucarelli P, Picchio M, Caporossi M, De Angelis F, Di Filippo A, Stipa F, Spaziani E.

Ann R Coll Surg Engl. 2013 May;95(4):246-51. doi: 10.1308/003588413X13511609958136. Retraction in: Johnson C, Mortensen N, Parker M. Ann R Coll Surg Engl. 2014 Mar;96(2):94.

17.

Excemplify: a flexible template based solution, parsing and managing data in spreadsheets for experimentalists.

Shi L, Jong L, Wittig U, Lucarelli P, Stepath M, Mueller S, D'Alessandro LA, Klingmüller U, Müller W.

J Integr Bioinform. 2013 Apr 3;10(2):220. doi: 10.2390/biecoll-jib-2013-220.

PMID:
23549603
18.

Evaluation of the oncogenic risk of diffuse gastric polyposis. A case report.

Spaziani E, Picchio M, Di-Filippo A, Narilli P, Pacini L, Moretti V, Lucarelli P, De-Angelis F, Ragona G, Petrozza V.

Rev Esp Enferm Dig. 2012 Sep;104(9):493-6.

19.

Prevalence of adenoma of gallbladder, ultrasonographic and histological assessment in a retrospective series of 450 cholecystectomy.

Spaziani E, Di Filippo A, Picchio M, Lucarelli P, Pattaro G, De Angelis F, Francioni P, Vestri A, Petrozza V, Narilli F, Drudi FM, Stagnitti F.

Ann Ital Chir. 2013 Mar-Apr;84(2):159-63; discussion 163-4.

PMID:
22842911
20.

Dynamics and feedback loops in the transforming growth factor β signaling pathway.

Wegner K, Bachmann A, Schad JU, Lucarelli P, Sahle S, Nickel P, Meyer C, Klingmüller U, Dooley S, Kummer U.

Biophys Chem. 2012 Mar;162:22-34. doi: 10.1016/j.bpc.2011.12.003. Epub 2012 Jan 5.

PMID:
22284904
21.

A study of Adenosine-Deaminase genetic polymorphism in rheumatoid arthritis.

Sebastiani GD, Bottini N, Greco E, Saccucci P, Canu G, Lucarelli P, Gloria-Bottini F, Fontana L.

Int J Immunopathol Pharmacol. 2010 Jul-Sep;23(3):791-5.

PMID:
20943049
22.

A study of three polymorphic sites of the ADA gene in children with type 1 diabetes mellitus.

Saccucci P, Meloni GF, Verrotti A, Borgiani P, D'Annibale F, Giannini C, Lucarelli P, Bottini N, Chiarelli F, Bottini E, Gloria-Bottini F.

J Pediatr Endocrinol Metab. 2010 Mar;23(3):283-90.

PMID:
20480728
23.

Genetic polymorphism and idiopathic generalized epilepsy. Evidence of interaction between haptoglobin and ACP1 systems.

Gloria-Bottini F, Lucarelli P, Saccucci P, Cozzoli E, Cerminara C, Curatolo P, Bottini E.

Neuropediatrics. 2008 Dec;39(6):357-8. doi: 10.1055/s-0029-1202834. Epub 2009 Jun 30.

PMID:
19569003
24.
25.

Lack of evidence for association between D2S124 and D2S111 polymorphisms of the SCN2A gene and idiopathic generalized epilepsy with generalized tonic clonic seizures.

Volzone A, Rizzo R, Gagliano A, Palmarino M, Lucarelli P, Arpino C, Curatolo P.

J Child Neurol. 2007 Jul;22(7):907-10.

PMID:
17715289
26.

Functional aspects of genetic variability in the GH genomic region.

Gloria-Bottini F, Amante A, Lucarelli P, Saccucci P, Martinoli R, Bottini E.

J Endocrinol. 2007 Apr;193(1):85-92.

PMID:
17400806
27.

Outcomes of child care health consultation services for child care providers in New Jersey: a pilot study.

Dellert JC, Gasalberti D, Sternas K, Lucarelli P, Hall J.

Pediatr Nurs. 2006 Nov-Dec;32(6):530-5, 565.

PMID:
17256290
28.

Genetic polymorphism within human growth hormone gene region and BMI in type 2 diabetes.

Gloria-Bottini F, Lucarelli P, Antonacci E, Saccucci P, De Lorenzo A, Bottini E.

Acta Diabetol. 2006 Dec;43(4):99-102.

PMID:
17211558
29.

Association between D18S474 locus on chromosome 18q12 and idiopathic generalized epilepsy.

Lucarelli P, Rizzo R, Gagliano A, Palmarino M, Volzone A, Arpino C, Curatolo P.

Brain Dev. 2007 Jan;29(1):9-12. Epub 2006 Jun 21.

PMID:
16790332
30.

Serum glucose concentration and ACP1 genotype in healthy adult subjects.

Iannaccone U, Bergamaschi A, Magrini A, Marino G, Bottini N, Lucarelli P, Bottini E, Gloria-Bottini F.

Metabolism. 2005 Jul;54(7):891-4.

PMID:
15988697
31.

Lack of association between IDE genetic variability and Down's syndrome.

Arpino C, Piciullo A, Palmarino M, Saccucci P, Galasso C, Lucarelli P, Curatolo P.

Neurosci Lett. 2005 Jul 1-8;382(1-2):93-5. Epub 2005 Mar 25.

PMID:
15911128
32.
33.

Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex.

Bottini N, Meloni GF, Lucarelli P, Amante A, Saccucci P, Gloria-Bottini F, Bottini E.

Diabetes Metab Res Rev. 2005 Jul-Aug;21(4):353-8.

PMID:
15586390
34.

Convulsive disorder and genetic polymorphism. Association of idiopathic generalized epilepsy with haptoglobin polymorphism.

Saccucci P, Verdecchia M, Piciullo A, Bottini N, Rizzo R, Gloria-Bottini F, Lucarelli P, Curatolo P.

Neurogenetics. 2004 Dec;5(4):245-8. Epub 2004 Oct 14.

PMID:
15490286
35.

Association between presenilin-1 -48C/T polymorphism and Down's syndrome.

Lucarelli P, Piciullo A, Palmarino M, Verdecchia M, Saccucci P, Arpino C, Curatolo P.

Neurosci Lett. 2004 Aug 26;367(1):88-91.

PMID:
15308304
36.

Type 2 diabetes and the genetics of signal transduction: a study of interaction between adenosine deaminase and acid phosphatase locus 1 polymorphisms.

Bottini N, Gloria-Bottini F, Borgiani P, Antonacci E, Lucarelli P, Bottini E.

Metabolism. 2004 Aug;53(8):995-1001.

PMID:
15281007
37.

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes.

Bottini N, Musumeci L, Alonso A, Rahmouni S, Nika K, Rostamkhani M, MacMurray J, Meloni GF, Lucarelli P, Pellecchia M, Eisenbarth GS, Comings D, Mustelin T.

Nat Genet. 2004 Apr;36(4):337-8. Epub 2004 Mar 7.

PMID:
15004560
38.

The role of -850 tumor necrosis factor-alpha and apolipoprotein E genetic polymorphism in patients with Down's syndrome-related dementia.

Lucarelli P, Piciullo A, Verdecchia M, Palmarino M, Arpino C, Curatolo P.

Neurosci Lett. 2003 Nov 27;352(1):29-32.

PMID:
14615042
39.

Association study of autistic disorder and chromosome 16p.

Lucarelli P, Palminiello S, Saccucci P, Bottini N, De Luca D, Elia M, Fiumara A, Curatolo P.

Am J Med Genet A. 2003 Jun 1;119A(2):242-6. No abstract available.

PMID:
12749074
40.

Association of the ACP1 genotype with metabolic parameters upon initial diagnosis of type 1 diabetes.

Meloni G, Bottini N, Borgiani P, Lucarelli P, Meloni T, Bottini E.

Med Sci Monit. 2003 Mar;9(3):CR105-8.

PMID:
12640337
41.

Convulsive disorder and the genetics of signal transduction; a study of a low molecular weight protein tyrosine phosphatase in a pediatric sample.

Bottini N, Saccucci P, Piciullo A, Iannetti P, Lucarini N, Lucarelli P, Gloria-Bottini F, Curatolo P.

Neurosci Lett. 2002 Nov 29;333(3):159-62.

PMID:
12429372
42.

Raising the bar for health and safety in child care.

Lucarelli P.

Pediatr Nurs. 2002 May-Jun;28(3):239-41, 291. Review.

PMID:
12087643
43.

Health promotion and education in youth correctional facilities.

Greene E, Lucarelli P, Shocksnider J.

Pediatr Nurs. 1999 May-Jun;25(3):312-4.

PMID:
12024350
44.

Two-loci ADA haplotypes in autistic disorder.

Lucarelli P, Saccucci P, Bottini N, De Luca D, Fiumara A, Elia M, Bottini N, Porfirio MC, Curatolo P.

Am J Med Genet. 2002 Apr 1;108(4):339-40. No abstract available.

PMID:
11920843
45.

Genotypes of cytosolic low-molecular-weight protein-tyrosine-phosphatase correlate with age at onset of type 1 diabetes in a sex-specific manner.

Bottini N, Meloni GF, Borgiani P, Giorgini A, Buzzetti R, Pozzilli P, Lucarelli P, Gloria-Bottini F.

Metabolism. 2002 Apr;51(4):419-22.

PMID:
11912546
47.

ACP1 and human adaptability: association with past malarial morbidity in the Sardinian population.

Bottini E, Palmarino R, Lucarelli P, Lista F, Bottini N.

Am J Hum Biol. 2001 Nov-Dec;13(6):753-60.

PMID:
11748814
48.

Adenosine deaminase-acid phosphatase association and the environment: A study in a continental Italian population.

Gloria-Bottini F, Lucarelli P, Lucarini N, Bottini E.

Am J Hum Biol. 2000 Mar;12(2):214-220.

PMID:
11534018
49.

Birth weight and parental PGM1 alleles.

Gloria-Bottini F, Lucarini N, La Torre M, Lucarelli P, Bottini E.

Am J Hum Biol. 2001 May-Jun;13(3):417-20.

PMID:
11460908
50.

Autism: evidence of association with adenosine deaminase genetic polymorphism.

Bottini N, De Luca D, Saccucci P, Fiumara A, Elia M, Porfirio MC, Lucarelli P, Curatolo P.

Neurogenetics. 2001 Mar;3(2):111-3.

PMID:
11354825

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