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Items: 16


Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling.

Luca VC, Miao Y, Li X, Hollander MJ, Kuo CJ, Garcia KC.

PLoS One. 2020 Jan 8;15(1):e0226928. doi: 10.1371/journal.pone.0226928. eCollection 2020.


Molecular engineering strategies for visualizing low-affinity protein complexes.

Ming Q, Gonzalez-Perez D, Luca VC.

Exp Biol Med (Maywood). 2019 Dec;244(17):1559-1567. doi: 10.1177/1535370219855401. Epub 2019 Jun 11. No abstract available. Erratum in: Exp Biol Med (Maywood). 2019 Jul 17;:1535370219867057.


Inhibition of Delta-induced Notch signaling using fucose analogs.

Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS.

Nat Chem Biol. 2018 Jan;14(1):65-71. doi: 10.1038/nchembio.2520. Epub 2017 Nov 27.


Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.

Lim JS, Ibaseta A, Fischer MM, Cancilla B, O'Young G, Cristea S, Luca VC, Yang D, Jahchan NS, Hamard C, Antoine M, Wislez M, Kong C, Cain J, Liu YW, Kapoun AM, Garcia KC, Hoey T, Murriel CL, Sage J.

Nature. 2017 May 18;545(7654):360-364. doi: 10.1038/nature22323. Epub 2017 May 10.


Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal.

Yan KS, Janda CY, Chang J, Zheng GXY, Larkin KA, Luca VC, Chia LA, Mah AT, Han A, Terry JM, Ootani A, Roelf K, Lee M, Yuan J, Li X, Bolen CR, Wilhelmy J, Davies PS, Ueno H, von Furstenberg RJ, Belgrader P, Ziraldo SB, Ordonez H, Henning SJ, Wong MH, Snyder MP, Weissman IL, Hsueh AJ, Mikkelsen TS, Garcia KC, Kuo CJ.

Nature. 2017 May 11;545(7653):238-242. doi: 10.1038/nature22313. Epub 2017 May 3.


Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.

Luca VC, Kim BC, Ge C, Kakuda S, Wu D, Roein-Peikar M, Haltiwanger RS, Zhu C, Ha T, Garcia KC.

Science. 2017 Mar 24;355(6331):1320-1324. doi: 10.1126/science.aaf9739. Epub 2017 Mar 2.


A Library of Infectious Hepatitis C Viruses with Engineered Mutations in the E2 Gene Reveals Growth-Adaptive Mutations That Modulate Interactions with Scavenger Receptor Class B Type I.

Zuiani A, Chen K, Schwarz MC, White JP, Luca VC, Fremont DH, Wang D, Evans MJ, Diamond MS.

J Virol. 2016 Nov 14;90(23):10499-10512. doi: 10.1128/JVI.01011-16. Print 2016 Dec 1.


Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

Spangler JB, Tomala J, Luca VC, Jude KM, Dong S, Ring AM, Votavova P, Pepper M, Kovar M, Garcia KC.

Immunity. 2015 May 19;42(5):815-25. doi: 10.1016/j.immuni.2015.04.015.


Structural biology. Structural basis for Notch1 engagement of Delta-like 4.

Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC.

Science. 2015 Feb 20;347(6224):847-53. doi: 10.1126/science.1261093.


Structure of the St. Louis encephalitis virus postfusion envelope trimer.

Luca VC, Nelson CA, Fremont DH.

J Virol. 2013 Jan;87(2):818-28. doi: 10.1128/JVI.01950-12. Epub 2012 Oct 31.


Crystal structure of the Japanese encephalitis virus envelope protein.

Luca VC, AbiMansour J, Nelson CA, Fremont DH.

J Virol. 2012 Feb;86(4):2337-46. doi: 10.1128/JVI.06072-11. Epub 2011 Dec 7.


Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature.

Sabo MC, Luca VC, Ray SC, Bukh J, Fremont DH, Diamond MS.

Virology. 2012 Jan 20;422(2):174-84. doi: 10.1016/j.virol.2011.10.023. Epub 2011 Nov 12.


Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step.

Sabo MC, Luca VC, Prentoe J, Hopcraft SE, Blight KJ, Yi M, Lemon SM, Ball JK, Bukh J, Evans MJ, Fremont DH, Diamond MS.

J Virol. 2011 Jul;85(14):7005-19. doi: 10.1128/JVI.00586-11. Epub 2011 May 4.


The effects of dietary flaxseed supplementation on lipid metabolism in streptozotocin-induced diabetic hamsters.

Haliga R, Mocanu V, Oboroceanu T, Stitt PA, Luca VC.

Rev Med Chir Soc Med Nat Iasi. 2007 Apr-Jun;111(2):472-6.


[The history of experimental diabetes in Iaşi ].

Luca VC, Mocanu V.

Rev Med Chir Soc Med Nat Iasi. 2003 Jan-Mar;107(1):227-31. Romanian.


[The influence of body weight upon the function of ovarian axis].

Mocanu V, Luca VC, Stoica AR, Zbranca E.

Rev Med Chir Soc Med Nat Iasi. 2001 Jul-Sep;105(3):469-74. Review. Romanian.


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