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Items: 1 to 50 of 100

1.

Human Memory Th17 Cell Populations Change Into Anti-inflammatory Cells With Regulatory Capacity Upon Exposure to Active Vitamin D.

Dankers W, Davelaar N, van Hamburg JP, van de Peppel J, Colin EM, Lubberts E.

Front Immunol. 2019 Jul 17;10:1504. doi: 10.3389/fimmu.2019.01504. eCollection 2019.

2.

Lack of IL-17 Receptor A signaling aggravates lymphoproliferation in C57BL/6 lpr mice.

Corneth OBJ, Schaper F, Luk F, Asmawidjaja PS, Mus AMC, Horst G, Heeringa P, Hendriks RW, Westra J, Lubberts E.

Sci Rep. 2019 Mar 11;9(1):4032. doi: 10.1038/s41598-019-39483-w.

3.

The anti-inflammatory potency of biologics targeting tumour necrosis factor-α, interleukin (IL)-17A, IL-12/23 and CD20 in hidradenitis suppurativa: an ex vivo study.

Vossen ARJV, Ardon CB, van der Zee HH, Lubberts E, Prens EP.

Br J Dermatol. 2019 Aug;181(2):314-323. doi: 10.1111/bjd.17641. Epub 2019 Apr 12.

PMID:
30657173
4.

1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade.

Dankers W, González-Leal C, Davelaar N, Asmawidjaja PS, Mus AMC, Hazes JMW, Colin EM, Lubberts E.

Arthritis Res Ther. 2018 Sep 20;20(1):212. doi: 10.1186/s13075-018-1706-9.

5.

House dust mite-driven neutrophilic airway inflammation in mice with TNFAIP3-deficient myeloid cells is IL-17-independent.

Vroman H, Das T, Bergen IM, van Hulst JAC, Ahmadi F, van Loo G, Lubberts E, Hendriks RW, Kool M.

Clin Exp Allergy. 2018 Dec;48(12):1705-1714. doi: 10.1111/cea.13262. Epub 2018 Sep 27.

PMID:
30171721
6.

T helper 17.1 cells associate with multiple sclerosis disease activity: perspectives for early intervention.

van Langelaar J, van der Vuurst de Vries RM, Janssen M, Wierenga-Wolf AF, Spilt IM, Siepman TA, Dankers W, Verjans GMGM, de Vries HE, Lubberts E, Hintzen RQ, van Luijn MM.

Brain. 2018 May 1;141(5):1334-1349. doi: 10.1093/brain/awy069.

PMID:
29659729
7.

From patients with arthralgia, pre-RA and recently diagnosed RA: what is the current status of understanding RA pathogenesis?

Molendijk M, Hazes JM, Lubberts E.

RMD Open. 2018 Jan 12;4(1):e000256. doi: 10.1136/rmdopen-2016-000256. eCollection 2018. Review.

8.

A cellular and molecular view of T helper 17 cell plasticity in autoimmunity.

Stadhouders R, Lubberts E, Hendriks RW.

J Autoimmun. 2018 Feb;87:1-15. doi: 10.1016/j.jaut.2017.12.007. Epub 2017 Dec 22. Review.

9.

The role of IL-23 receptor signaling in inflammation-mediated erosive autoimmune arthritis and bone remodeling.

Razawy W, van Driel M, Lubberts E.

Eur J Immunol. 2018 Feb;48(2):220-229. doi: 10.1002/eji.201646787. Epub 2018 Jan 15. Review.

10.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Cossarizza A, Chang HD, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Dreher A, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Geginat J, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mirrer D, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O'Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruckert B, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J.

Eur J Immunol. 2017 Oct;47(10):1584-1797. doi: 10.1002/eji.201646632. No abstract available.

11.

Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia.

Paerewijck O, Maertens B, Dreesen L, Van Meulder F, Peelaers I, Ratman D, Li RW, Lubberts E, De Bosscher K, Geldhof P.

Sci Rep. 2017 Aug 17;7(1):8520. doi: 10.1038/s41598-017-08590-x.

12.

Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases.

Mourik BC, Lubberts E, de Steenwinkel JEM, Ottenhoff THM, Leenen PJM.

Front Immunol. 2017 Apr 5;8:294. doi: 10.3389/fimmu.2017.00294. eCollection 2017. Review.

13.

Vitamin D in Autoimmunity: Molecular Mechanisms and Therapeutic Potential.

Dankers W, Colin EM, van Hamburg JP, Lubberts E.

Front Immunol. 2017 Jan 20;7:697. doi: 10.3389/fimmu.2016.00697. eCollection 2016. Review.

14.

Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease.

Corneth OBJ, Verstappen GMP, Paulissen SMJ, de Bruijn MJW, Rip J, Lukkes M, van Hamburg JP, Lubberts E, Bootsma H, Kroese FGM, Hendriks RW.

Arthritis Rheumatol. 2017 Jun;69(6):1313-1324. doi: 10.1002/art.40059. Epub 2017 May 10.

15.

Experimental Arthritis Mouse Models Driven by Adaptive and/or Innate Inflammation.

Razawy W, Alves CH, Molendijk M, Asmawidjaja PS, Mus AMC, Lubberts E.

Methods Mol Biol. 2017;1559:391-410. doi: 10.1007/978-1-4939-6786-5_27.

PMID:
28063059
16.

JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa.

Boor PPC, de Ruiter PE, Asmawidjaja PS, Lubberts E, van der Laan LJW, Kwekkeboom J.

Transl Res. 2017 Oct;188:67-79. doi: 10.1016/j.trsl.2016.11.006. Epub 2016 Nov 20.

PMID:
27931982
17.

Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice.

Corneth OB, Reijmers RM, Mus AM, Asmawidjaja PS, van Hamburg JP, Papazian N, Siegers JY, Mourcin F, Amin R, Tarte K, Hendriks RW, Cupedo T, Lubberts E.

Eur J Immunol. 2016 Jun;46(6):1404-14. doi: 10.1002/eji.201546241. Epub 2016 May 12.

18.

Human mast cells capture, store, and release bioactive, exogenous IL-17A.

Noordenbos T, Blijdorp I, Chen S, Stap J, Mul E, Cañete JD, Lubberts E, Yeremenko N, Baeten D.

J Leukoc Biol. 2016 Sep;100(3):453-62. doi: 10.1189/jlb.3HI1215-542R. Epub 2016 Mar 31.

PMID:
27034403
19.

Association of Increased Treg Cell Levels With Elevated Indoleamine 2,3-Dioxygenase Activity and an Imbalanced Kynurenine Pathway in Interferon-Positive Primary Sjögren's Syndrome.

Maria NI, van Helden-Meeuwsen CG, Brkic Z, Paulissen SM, Steenwijk EC, Dalm VA, van Daele PL, Martin van Hagen P, Kroese FG, van Roon JA, Harkin A, Dik WA, Drexhage HA, Lubberts E, Versnel MA.

Arthritis Rheumatol. 2016 Jul;68(7):1688-99. doi: 10.1002/art.39629.

20.

Animal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside-a Comprehensive Review.

Alves CH, Farrell E, Vis M, Colin EM, Lubberts E.

Clin Rev Allergy Immunol. 2016 Aug;51(1):27-47. doi: 10.1007/s12016-015-8522-7. Review.

21.

CCR6(+) Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis.

Paulissen SM, van Hamburg JP, Davelaar N, Vroman H, Hazes JM, de Jong PH, Lubberts E.

Arthritis Res Ther. 2015 Nov 30;17:344. doi: 10.1186/s13075-015-0800-5.

22.

Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis.

Alves CH, Ober-Blöbaum JL, Brouwers-Haspels I, Asmawidjaja PS, Mus AM, Razawy W, Molendijk M, Clausen BE, Lubberts E.

PLoS One. 2015 Nov 20;10(11):e0142972. doi: 10.1371/journal.pone.0142972. eCollection 2015.

23.

Arthritic and non-arthritic synovial fluids modulate IL10 and IL1RA gene expression in differentially activated primary human monocytes.

Lopa S, Leijs MJ, Moretti M, Lubberts E, van Osch GJ, Bastiaansen-Jenniskens YM.

Osteoarthritis Cartilage. 2015 Nov;23(11):1853-7. doi: 10.1016/j.joca.2015.06.003. Review.

24.

Preventive effects of dietary hydroxytyrosol acetate, an extra virgin olive oil polyphenol in murine collagen-induced arthritis.

Rosillo MA, Sánchez-Hidalgo M, González-Benjumea A, Fernández-Bolaños JG, Lubberts E, Alarcón-de-la-Lastra C.

Mol Nutr Food Res. 2015 Dec;59(12):2537-46. doi: 10.1002/mnfr.201500304. Epub 2015 Oct 12.

PMID:
26382723
25.

The IL-23-IL-17 axis in inflammatory arthritis.

Lubberts E.

Nat Rev Rheumatol. 2015 Oct;11(10):562. doi: 10.1038/nrrheum.2015.128. Epub 2015 Sep 15.

PMID:
26369609
26.

Decreased serum cell-free DNA levels in rheumatoid arthritis.

Dunaeva M, Buddingh' BC, Toes RE, Luime JJ, Lubberts E, Pruijn GJ.

Auto Immun Highlights. 2015 Aug;6(1-2):23-30. doi: 10.1007/s13317-015-0066-6. Epub 2015 Jun 27.

27.

Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer.

Punt S, Fleuren GJ, Kritikou E, Lubberts E, Trimbos JB, Jordanova ES, Gorter A.

Oncoimmunology. 2015 Feb 3;4(1):e984539. eCollection 2015 Jan.

28.

The IL-23-IL-17 axis in inflammatory arthritis.

Lubberts E.

Nat Rev Rheumatol. 2015 Jul;11(7):415-29. doi: 10.1038/nrrheum.2015.53. Epub 2015 Apr 28. Review. Erratum in: Nat Rev Rheumatol. 2015 Oct;11(10):562.

PMID:
25907700
29.

The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis.

Paulissen SM, van Hamburg JP, Dankers W, Lubberts E.

Cytokine. 2015 Jul;74(1):43-53. doi: 10.1016/j.cyto.2015.02.002. Epub 2015 Mar 28. Review.

PMID:
25828206
30.

Surrogate light chain expression beyond the pre-B cell stage promotes tolerance in a dose-dependent fashion.

Kil LP, Corneth OB, de Bruijn MJ, Asmawidjaja PS, Krause A, Lubberts E, van Loo PF, Hendriks RW.

J Autoimmun. 2015 Feb;57:30-41. doi: 10.1016/j.jaut.2014.11.008. Epub 2014 Dec 16.

PMID:
25523463
31.

A human vitamin D receptor mutation causes rickets and impaired Th1/Th17 responses.

van der Eerden BC, van der Heyden JC, van Hamburg JP, Schreuders-Koedam M, Asmawidjaja PS, de Muinck Keizer-Schrama SM, Boot AM, Lubberts E, Drop SL, van Leeuwen JP.

Bone. 2014 Dec;69:6-11. doi: 10.1016/j.bone.2014.08.005. Epub 2014 Sep 6.

PMID:
25201466
32.

Response to ‘T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?’ – Authors’ reply.

Brkic Z, Corneth OB, Versnel MA, Lubberts E.

Arthritis Res Ther. 2014;16(3):410. No abstract available.

33.
34.

Giardia muris infection in mice is associated with a protective interleukin 17A response and induction of peroxisome proliferator-activated receptor alpha.

Dreesen L, De Bosscher K, Grit G, Staels B, Lubberts E, Bauge E, Geldhof P.

Infect Immun. 2014 Aug;82(8):3333-40. doi: 10.1128/IAI.01536-14. Epub 2014 May 27.

35.

FcγRIIb on myeloid cells rather than on B cells protects from collagen-induced arthritis.

Yilmaz-Elis AS, Ramirez JM, Asmawidjaja P, van der Kaa J, Mus AM, Brem MD, Claassens JW, Breukel C, Brouwers C, Mangsbo SM, Boross P, Lubberts E, Verbeek JS.

J Immunol. 2014 Jun 15;192(12):5540-7. doi: 10.4049/jimmunol.1303272. Epub 2014 May 19.

36.

T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?

Brkic Z, Corneth OB, van Helden-Meeuwsen CG, Dolhain RJ, Maria NI, Paulissen SM, Davelaar N, van Hamburg JP, van Daele PL, Dalm VA, van Hagen PM, Hazes JM, Versnel MA, Lubberts E.

Arthritis Res Ther. 2014 Mar 6;16(2):R62. doi: 10.1186/ar4499.

37.

Absence of interleukin-17 receptor a signaling prevents autoimmune inflammation of the joint and leads to a Th2-like phenotype in collagen-induced arthritis.

Corneth OB, Mus AM, Asmawidjaja PS, Klein Wolterink RG, van Nimwegen M, Brem MD, Hofman Y, Hendriks RW, Lubberts E.

Arthritis Rheumatol. 2014 Feb;66(2):340-9. doi: 10.1002/art.38229.

38.

Synovial fibroblasts directly induce Th17 pathogenicity via the cyclooxygenase/prostaglandin E2 pathway, independent of IL-23.

Paulissen SM, van Hamburg JP, Davelaar N, Asmawidjaja PS, Hazes JM, Lubberts E.

J Immunol. 2013 Aug 1;191(3):1364-72. doi: 10.4049/jimmunol.1300274. Epub 2013 Jul 1.

39.

Haemarthrosis stimulates the synovial fibrinolytic system in haemophilic mice.

Nieuwenhuizen L, Roosendaal G, Coeleveld K, Lubberts E, Biesma DH, Lafeber FP, Schutgens RE.

Thromb Haemost. 2013 Jul;110(1):173-83. doi: 10.1160/TH13-01-0080. Epub 2013 May 16.

PMID:
23677440
40.

Fibrates as therapy for osteoarthritis and rheumatoid arthritis? A systematic review.

van Eekeren IC, Clockaerts S, Bastiaansen-Jenniskens YM, Lubberts E, Verhaar JA, van Osch GJ, Bierma-Zeinstra SM.

Ther Adv Musculoskelet Dis. 2013 Feb;5(1):33-44. doi: 10.1177/1759720X12468659.

41.

IL-23 dependent and independent stages of experimental arthritis: no clinical effect of therapeutic IL-23p19 inhibition in collagen-induced arthritis.

Cornelissen F, Asmawidjaja PS, Mus AM, Corneth O, Kikly K, Lubberts E.

PLoS One. 2013;8(2):e57553. doi: 10.1371/journal.pone.0057553. Epub 2013 Feb 28.

42.

IL-17/Th17 mediated synovial inflammation is IL-22 independent.

van Hamburg JP, Corneth OB, Paulissen SM, Davelaar N, Asmawidjaja PS, Mus AM, Lubberts E.

Ann Rheum Dis. 2013 Oct;72(10):1700-7. doi: 10.1136/annrheumdis-2012-202373. Epub 2013 Jan 17.

PMID:
23328939
43.

Effect of Arthritic Synovial Fluids on the Expression of Immunomodulatory Factors by Mesenchymal Stem Cells: An Explorative in vitro Study.

Leijs MJ, van Buul GM, Lubberts E, Bos PK, Verhaar JA, Hoogduijn MJ, van Osch GJ.

Front Immunol. 2012 Aug 2;3:231. doi: 10.3389/fimmu.2012.00231. eCollection 2012.

44.

TNF blockade requires 1,25(OH)2D3 to control human Th17-mediated synovial inflammation.

van Hamburg JP, Asmawidjaja PS, Davelaar N, Mus AM, Cornelissen F, van Leeuwen JP, Hazes JM, Dolhain RJ, Bakx PA, Colin EM, Lubberts E.

Ann Rheum Dis. 2012 Apr;71(4):606-12. doi: 10.1136/annrheumdis-2011-200424. Epub 2012 Jan 4.

PMID:
22219138
45.

The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility.

Boross P, Arandhara VL, Martin-Ramirez J, Santiago-Raber ML, Carlucci F, Flierman R, van der Kaa J, Breukel C, Claassens JW, Camps M, Lubberts E, Salvatori D, Rastaldi MP, Ossendorp F, Daha MR, Cook HT, Izui S, Botto M, Verbeek JS.

J Immunol. 2011 Aug 1;187(3):1304-13. doi: 10.4049/jimmunol.1101194. Epub 2011 Jul 1.

46.

Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: rationale for combination treatment during arthritis.

Koenders MI, Marijnissen RJ, Devesa I, Lubberts E, Joosten LA, Roth J, van Lent PL, van de Loo FA, van den Berg WB.

Arthritis Rheum. 2011 Aug;63(8):2329-39. doi: 10.1002/art.30418.

47.

Imaging of activated macrophages in experimental osteoarthritis using folate-targeted animal single-photon-emission computed tomography/computed tomography.

Piscaer TM, Müller C, Mindt TL, Lubberts E, Verhaar JA, Krenning EP, Schibli R, De Jong M, Weinans H.

Arthritis Rheum. 2011 Jul;63(7):1898-907. doi: 10.1002/art.30363.

48.

Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression.

Toh ML, Gonzales G, Koenders MI, Tournadre A, Boyle D, Lubberts E, Zhou Y, Firestein GS, van den Berg WB, Miossec P.

PLoS One. 2010 Oct 15;5(10):e13416. doi: 10.1371/journal.pone.0013416.

49.
50.

Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis.

Mus AM, Cornelissen F, Asmawidjaja PS, van Hamburg JP, Boon L, Hendriks RW, Lubberts E.

Arthritis Rheum. 2010 Apr;62(4):1043-50. doi: 10.1002/art.27336.

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