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Role of type I interferons and innate immunity in systemic sclerosis: unbalanced activities on distinct cell types?

Barrat FJ, Lu TT.

Curr Opin Rheumatol. 2019 Aug 20. doi: 10.1097/BOR.0000000000000659. [Epub ahead of print]


Activation of Angiogenesis and Wound Healing in Diabetic Mice Using NO-Delivery Dinitrosyl Iron Complexes.

Chen YJ, Wu SC, Wang HC, Wu TH, Yuan SF, Lu TT, Liaw WF, Wang YM.

Mol Pharm. 2019 Sep 5. doi: 10.1021/acs.molpharmaceut.9b00586. [Epub ahead of print]


Immunopathogenesis of Juvenile Systemic Sclerosis.

Stevens AM, Torok KS, Li SC, Taber SF, Lu TT, Zulian F.

Front Immunol. 2019 Jun 25;10:1352. doi: 10.3389/fimmu.2019.01352. eCollection 2019. Review.


[Dry eye syndrome of deficient lacrima production treated with the acupoint thread-embedding therapy: a randomized controlled trial].

Liu J, Lu TT, Han DX, Wang C, Chen LF, Wang CY, Fang JQ.

Zhongguo Zhen Jiu. 2019 Jul 12;39(7):721-5. doi: 10.13703/j.0255-2930.2019.07.011. Chinese.


Disruption of the Gut Microbiome Increases the Risk of Periprosthetic Joint Infection in Mice.

Hernandez CJ, Yang X, Ji G, Niu Y, Sethuraman AS, Koressel J, Shirley M, Fields MW, Chyou S, Li TM, Luna M, Callahan RL, Ross FP, Lu TT, Brito IL, Carli AV, Bostrom MPG.

Clin Orthop Relat Res. 2019 Jun 17. doi: 10.1097/CORR.0000000000000851. [Epub ahead of print]


Immunopathogenesis of Pediatric Localized Scleroderma.

Torok KS, Li SC, Jacobe HM, Taber SF, Stevens AM, Zulian F, Lu TT.

Front Immunol. 2019 Apr 30;10:908. doi: 10.3389/fimmu.2019.00908. eCollection 2019. Review.


Synthetic methodology for preparation of dinitrosyl iron complexes.

Cho SL, Liao CJ, Lu TT.

J Biol Inorg Chem. 2019 Jun;24(4):495-515. doi: 10.1007/s00775-019-01668-z. Epub 2019 May 20. Review.


Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans.

Li ST, Lu TT, Xu XX, Ding Y, Li Z, Kitajima T, Dean N, Wang N, Gao XD.

Nat Commun. 2019 Apr 18;10(1):1813. doi: 10.1038/s41467-019-09752-3.


Fe in biosynthesis, translocation, and signal transduction of NO: toward bioinorganic engineering of dinitrosyl iron complexes into NO-delivery scaffolds for tissue engineering.

Hsiao HY, Chung CW, Santos JH, Villaflores OB, Lu TT.

Dalton Trans. 2019 Jul 2;48(26):9431-9453. doi: 10.1039/c9dt00777f.


Glucagon-like peptide-1 receptor agonists and risk of bone fracture in patients with type 2 diabetes: A meta-analysis of randomized controlled trials.

Cheng L, Hu Y, Li YY, Cao X, Bai N, Lu TT, Li GQ, Li N, Wang AN, Mao XM.

Diabetes Metab Res Rev. 2019 Apr 11:e3168. doi: 10.1002/dmrr.3168. [Epub ahead of print]


Lymphatic Function in Autoimmune Diseases.

Schwartz N, Chalasani MLS, Li TM, Feng Z, Shipman WD, Lu TT.

Front Immunol. 2019 Mar 20;10:519. doi: 10.3389/fimmu.2019.00519. eCollection 2019. Review.


Lipoprotein-associated phospholipase A2 is a risk factor for diabetic kidney disease.

Hu Y, Li TT, Zhou W, Lu TT, Li FF, Ding B, Liu BL, Xie XJ, Ma JH.

Diabetes Res Clin Pract. 2019 Apr;150:194-201. doi: 10.1016/j.diabres.2019.03.026. Epub 2019 Mar 20.


Berberine Alleviates Amyloid-beta Pathogenesis Via Activating LKB1/AMPK Signaling in the Brain of APP/PS1 Transgenic Mice.

Cai ZY, Wang CL, Lu TT, Yang WM.

Curr Mol Med. 2019;19(5):342-348. doi: 10.2174/1566524019666190315164120.


The effect of short-term intensive insulin therapy on circulating T cell subpopulations in patients with newly diagnosed type 2 diabetes mellitus.

Cheng L, Yang F, Cao X, Li GQ, Lu TT, Zhu YQ, Hu Y, Mao XM.

Diabetes Res Clin Pract. 2019 Mar;149:107-114. doi: 10.1016/j.diabres.2019.02.007. Epub 2019 Feb 10.


Monodisperse Six-Armed Starbursts based on Truxene-Cored Multibranched Oligofluorenes: Design, Synthesis, and Stabilized Lasing Characteristics.

Zhang H, Liu X, Lu TT, Lv P, Lai WY.

Chemistry. 2019 Mar 12;25(15):3909-3917. doi: 10.1002/chem.201805813. Epub 2019 Feb 13.


Transformation of the hydride-containing dinitrosyl iron complex [(NO)2Fe(η2-BH4)]- into [(NO)2Fe(η3-HCS2)]-via reaction with CS2.

Huang HC, Ching WM, Tseng YT, Chen CH, Lu TT.

Dalton Trans. 2019 May 7;48(18):5897-5902. doi: 10.1039/c8dt04714f.


[Operating Characteristics of a DPR-SNED System Treating Low C/N Municipal Wastewater and Nitrate-containing Sewage].

Du SM, Yu DS, Bi CX, Wang XX, Chen GH, Yuan MF, Zhen JY, Zhang F, Lü TT.

Huan Jing Ke Xue. 2019 Feb 8;40(2):791-798. doi: 10.13227/j.hjkx.201808090. Chinese.


[Characteristics of Ammonia Adsorption and Kinetics by Nitrifying Sludge Immobilized Pellets].

Yu DS, Lü TT, Chen GH, Wang XX, Tang P, Huang S, Liu CC, Du SM.

Huan Jing Ke Xue. 2019 Feb 8;40(2):774-782. doi: 10.13227/j.hjkx.201805061. Chinese.


Association of high circulating testosterone with increased glycaemic variability in type 2 diabetes: A cross-sectional study in China.

Ding B, Sun R, Zhai XF, Lu TT, Cheng L, Li FF, Hu Y, Ma JH.

Diabetes Metab Res Rev. 2019 May;35(4):e3126. doi: 10.1002/dmrr.3126. Epub 2019 Jan 23.


Bioinorganic Chemistry of the Natural [Fe(NO)2] Motif: Evolution of a Functional Model for NO-Related Biomedical Application and Revolutionary Development of a Translational Model.

Lu TT, Wang YM, Hung CH, Chiou SJ, Liaw WF.

Inorg Chem. 2018 Oct 15;57(20):12425-12443. doi: 10.1021/acs.inorgchem.8b01818. Epub 2018 Sep 24. Review.


A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.

Shipman WD, Chyou S, Ramanathan A, Izmirly PM, Sharma S, Pannellini T, Dasoveanu DC, Qing X, Magro CM, Granstein RD, Lowes MA, Pamer EG, Kaplan DH, Salmon JE, Mehrara BJ, Young JW, Clancy RM, Blobel CP, Lu TT.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaap9527. doi: 10.1126/scitranslmed.aap9527.


Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment.

Salinas CBG, Lu TT, Gabery S, Marstal K, Alanentalo T, Mercer AJ, Cornea A, Conradsen K, Hecksher-Sørensen J, Dahl AB, Knudsen LB, Secher A.

Sci Rep. 2018 Jul 9;8(1):10310. doi: 10.1038/s41598-018-28496-6.


[Characteristics and Performance of Embedded ANAMMOX Bacteria in Treating Saline Wastewater].

Shan XJ, Yu DS, Li J, Chen GH, Feng L, Lü TT, Shao Q.

Huan Jing Ke Xue. 2018 Apr 8;39(4):1677-1687. doi: 10.13227/j.hjkx.201706159. Chinese.


Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL-22Fc): A Potential Therapy for Epithelial Injury.

Rothenberg ME, Wang Y, Lekkerkerker A, Danilenko DM, Maciuca R, Erickson R, Herman A, Stefanich E, Lu TT.

Clin Pharmacol Ther. 2019 Jan;105(1):177-189. doi: 10.1002/cpt.1164. Epub 2018 Aug 12.


[Stereotactic biopsy in the accurate diagnosis of lesions in the brain stem and deep brain].

Qin F, Huang ZC, Cai MQ, Xu XF, Lu TT, Dong Q, Wu AM, Lu ZZ, Zhao C, Guo Y.

Zhonghua Yi Xue Za Zhi. 2018 Jun 12;98(22):1771-1774. doi: 10.3760/cma.j.issn.0376-2491.2018.22.009. Chinese.


Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes.

Huang HW, Lin YH, Lin MH, Huang YR, Chou CH, Hong HC, Wang MR, Tseng YT, Liao PC, Chung MC, Ma YJ, Wu SC, Chuang YJ, Wang HD, Wang YM, Huang HD, Lu TT, Liaw WF.

J Biol Inorg Chem. 2018 Jul;23(5):775-784. doi: 10.1007/s00775-018-1569-1. Epub 2018 Jun 1.


The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.

Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA.

Cell Metab. 2018 Jun 5;27(6):1294-1308.e7. doi: 10.1016/j.cmet.2018.04.013. Epub 2018 May 10.


Correlation between resistin gene polymorphism and clinical aspects of lung cancer.

Hu WW, Tang CH, Sun Y, Lu TT, Jiang P, Wu YM, Wang CQ, Yang SF, Su CM.

Medicine (Baltimore). 2017 Dec;96(52):e9485. doi: 10.1097/MD.0000000000009485.


Situational Analysis of Low-density Lipoprotein Cholesterol Control and the Use of Statin Therapy in Diabetes Patients Treated in Community Hospitals in Nanjing, China.

Ouyang XJ, Zhang YQ, Chen JH, Li T, Lu TT, Bian RW.

Chin Med J (Engl). 2018 Feb 5;131(3):295-300. doi: 10.4103/0366-6999.223857.


G.A.M.E.: GPU-accelerated mixture elucidator.

Schurz A, Su BH, Tu YS, Lu TT, Lin OA, Tseng YJ.

J Cheminform. 2017 Sep 15;9(1):50. doi: 10.1186/s13321-017-0238-7.


Eosinophilic biomarkers for detection of acute exacerbation of chronic obstructive pulmonary disease with or without pulmonary embolism.

Yang QF, Lu TT, Shu CM, Feng LF, Chang HT, Ji QY.

Exp Ther Med. 2017 Oct;14(4):3198-3206. doi: 10.3892/etm.2017.4876. Epub 2017 Aug 2.


[A case of glutathione synthetase deficiency caused by GSS gene mutations].

Wang HJ, Lu TT, Li DX.

Zhonghua Er Ke Za Zhi. 2017 Aug 2;55(8):632-633. doi: 10.3760/cma.j.issn.0578-1310.2017.08.017. Chinese. No abstract available.


Directly monitor protein rearrangement on a nanosecond-to-millisecond time-scale.

Chen EH, Lu TT, Hsu JC, Tseng YJ, Lim TS, Chen RP.

Sci Rep. 2017 Aug 18;7(1):8691. doi: 10.1038/s41598-017-08385-0.


The roles of dermal white adipose tissue loss in scleroderma skin fibrosis.

Marangoni RG, Lu TT.

Curr Opin Rheumatol. 2017 Nov;29(6):585-590. doi: 10.1097/BOR.0000000000000437. Review.


Diagnostic Significance of Mycobacterium tuberculosis T-cell Assays for Active Tuberculosis.

Xuan WX, Lu TT, Wang Z, An YX, Zhang XJ.

Chin Med J (Engl). 2017 Apr 5;130(7):811-816. doi: 10.4103/0366-6999.202738.


Tertiary lymphoid organs in systemic autoimmune diseases:  pathogenic or protective?

Shipman WD, Dasoveanu DC, Lu TT.

F1000Res. 2017 Feb 28;6:196. doi: 10.12688/f1000research.10595.1. eCollection 2017. Review.


Elevated Levels of Plasma Superoxide Dismutases 1 and 2 in Patients with Coronary Artery Disease.

Peng JR, Lu TT, Chang HT, Ge X, Huang B, Li WM.

Biomed Res Int. 2016;2016:3708905. Epub 2016 Oct 17.


Dendritic cells maintain dermal adipose-derived stromal cells in skin fibrosis.

Chia JJ, Zhu T, Chyou S, Dasoveanu DC, Carballo C, Tian S, Magro CM, Rodeo S, Spiera RF, Ruddle NH, McGraw TE, Browning JL, Lafyatis R, Gordon JK, Lu TT.

J Clin Invest. 2016 Nov 1;126(11):4331-4345. doi: 10.1172/JCI85740. Epub 2016 Oct 10.


Regulation of Lymph Node Vascular-Stromal Compartment by Dendritic Cells.

Dasoveanu DC, Shipman WD, Chia JJ, Chyou S, Lu TT.

Trends Immunol. 2016 Nov;37(11):764-777. doi: 10.1016/ Epub 2016 Sep 13. Review.


Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC.

Colombel JF, Keir ME, Scherl A, Zhao R, de Hertogh G, Faubion WA, Lu TT.

Gut. 2017 Dec;66(12):2063-2068. doi: 10.1136/gutjnl-2016-312307. Epub 2016 Sep 2.


Rationally introduce multi-competitive binding interactions in supramolecular gels: a simple and efficient approach to develop multi-analyte sensor array.

Lin Q, Lu TT, Zhu X, Wei TB, Li H, Zhang YM.

Chem Sci. 2016 Aug 1;7(8):5341-5346. doi: 10.1039/c6sc00955g. Epub 2016 Apr 25.


[NiIII(OMe)]-mediated reductive activation of CO2 affording a Ni(κ1-OCO) complex.

Chiou TW, Tseng YM, Lu TT, Weng TC, Sokaras D, Ho WC, Kuo TS, Jang LY, Lee JF, Liaw WF.

Chem Sci. 2016 Jun 1;7(6):3640-3644. doi: 10.1039/c5sc04652a. Epub 2016 Feb 24.


Immobilization of dehydrogenase onto epoxy-functionalized nanoparticles for synthesis of (R)-mandelic acid.

Jiang XP, Lu TT, Liu CH, Ling XM, Zhuang MY, Zhang JX, Zhang YW.

Int J Biol Macromol. 2016 Jul;88:9-17. doi: 10.1016/j.ijbiomac.2016.03.031. Epub 2016 Mar 16.


Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.

Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Tung YC, Lam B, Larder R, Yeo GS, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA.

Cell. 2016 Jan 28;164(3):353-64. doi: 10.1016/j.cell.2015.12.025.


Adiponectin Induces Oncostatin M Expression in Osteoblasts through the PI3K/Akt Signaling Pathway.

Su CM, Lee WL, Hsu CJ, Lu TT, Wang LH, Xu GH, Tang CH.

Int J Mol Sci. 2015 Dec 25;17(1). pii: E29. doi: 10.3390/ijms17010029.


Magnetic resonance angiography manifestations and prognostic significance in HIV-negative tuberculosis meningitis.

Lu TT, Lin XQ, Zhang L, Cai W, Dai YQ, Lu ZZ, Wu AM, Bao J, Yang Y, Hu XQ, Lu ZQ.

Int J Tuberc Lung Dis. 2015 Dec;19(12):1448-54. doi: 10.5588/ijtld.15.0113.


Magnetic resonance enterography is feasible and reliable in multicenter clinical trials in patients with Crohn's disease, and may help select subjects with active inflammation.

Coimbra AJ, Rimola J, O'Byrne S, Lu TT, Bengtsson T, de Crespigny A, Luca D, Rutgeerts P, Bruining DH, Fidler JL, Sandborn WJ, Santillan CS, Higgins PD, Al-Hawary MM, Vermeire S, Vanbeckevoort D, Vanslembrouck R, Peyrin-Biroulet L, Laurent V, Herrmann KA, Panes J.

Aliment Pharmacol Ther. 2016 Jan;43(1):61-72. doi: 10.1111/apt.13453. Epub 2015 Nov 9.


Agreement Between Rectosigmoidoscopy and Colonoscopy Analyses of Disease Activity and Healing in Patients With Ulcerative Colitis.

Colombel JF, Ordás I, Ullman T, Rutgeerts P, Chai A, O'Byrne S, Lu TT, Panés J.

Gastroenterology. 2016 Feb;150(2):389-95.e3. doi: 10.1053/j.gastro.2015.10.016. Epub 2015 Oct 23.


Development of a Dinitrosyl Iron Complex Molecular Catalyst into a Hydrogen Evolution Cathode.

Chiou TW, Lu TT, Wu YH, Yu YJ, Chu LK, Liaw WF.

Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14824-9. doi: 10.1002/anie.201508351. Epub 2015 Oct 6.


To Transfer or Not to Transfer? Development of a Dinitrosyl Iron Complex as a Nitroxyl Donor for the Nitroxylation of an Fe(III) -Porphyrin Center.

Tseng YT, Chen CH, Lin JY, Li BH, Lu YH, Lin CH, Chen HT, Weng TC, Sokaras D, Chen HY, Soo YL, Lu TT.

Chemistry. 2015 Dec 1;21(49):17570-3. doi: 10.1002/chem.201503176. Epub 2015 Oct 22.


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