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miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease.

Fernández-Tussy P, Fernández-Ramos D, Lopitz-Otsoa F, Simón J, Barbier-Torres L, Gomez-Santos B, Nuñez-Garcia M, Azkargorta M, Gutiérrez-de Juan V, Serrano-Macia M, Rodríguez-Agudo R, Iruzubieta P, Anguita J, Castro RE, Champagne D, Rincón M, Elortza F, Arslanow A, Krawczyk M, Lammert F, Kirchmeyer M, Behrmann I, Crespo J, Lu SC, Mato JM, Varela-Rey M, Aspichueta P, Delgado TC, Martínez-Chantar ML.

Mol Metab. 2019 Nov;29:40-54. doi: 10.1016/j.molmet.2019.08.008. Epub 2019 Aug 16.


Quantitative Physical Fitness Measures Inversely Associated With Myopia Severity in Military Males: The CHIEF Study.

Lu SC, Liu FY, Hsieh CJ, Su FY, Wong TY, Tai MC, Chen JT, Lin GM.

Am J Mens Health. 2019 Sep-Oct;13(5):1557988319883766. doi: 10.1177/1557988319883766.


Electronegative LDL from Rabbits Fed with Atherogenic Diet Is Highly Proinflammatory.

Chang PY, Pai JH, Lai YS, Lu SC.

Mediators Inflamm. 2019 Aug 22;2019:6163130. doi: 10.1155/2019/6163130. eCollection 2019.


Current status of hepatocellular carcinoma detection: screening strategies and novel biomarkers.

Ayoub WS, Steggerda J, Yang JD, Kuo A, Sundaram V, Lu SC.

Ther Adv Med Oncol. 2019 Sep 6;11:1758835919869120. doi: 10.1177/1758835919869120. eCollection 2019. Review.


Glucose-Dependent Insulinotropic Polypeptide Receptor Therapies For The Treatment Of Obesity, Do Agonists = Antagonists?

Killion EA, Lu SC, Fort M, Yamada Y, Véniant MM, Lloyd DJ.

Endocr Rev. 2019 Sep 12. pii: bnz002. doi: 10.1210/endrev/bnz002. [Epub ahead of print]


Methionine adenosyltransferases in liver cancer.

Murray B, Barbier-Torres L, Fan W, Mato JM, Lu SC.

World J Gastroenterol. 2019 Aug 21;25(31):4300-4319. doi: 10.3748/wjg.v25.i31.4300. Review.


Musculoskeletal models of a human and bonobo finger: parameter identification and comparison to in vitro experiments.

Synek A, Lu SC, Vereecke EE, Nauwelaerts S, Kivell TL, Pahr DH.

PeerJ. 2019 Aug 9;7:e7470. doi: 10.7717/peerj.7470. eCollection 2019.


Long-term consequences of stopping HBIG and/or nucleotide analogues in liver transplant recipients administered hepatitis B vaccination to prevent HBV reinfection.

Duan BW, Tian LT, Lin DD, Zhang J, Guo QL, Wu JS, Zeng DB, Lu SC.

J Viral Hepat. 2019 Jul;26 Suppl 1:85-89. doi: 10.1111/jvh.13164.


Imaging Findings of Subcutaneous Human Dirofilariasis.

Alam SI, Nepal P, Lu SC, Elramadi A, Sapire JM.

Curr Probl Diagn Radiol. 2019 Jul 12. pii: S0363-0188(19)30158-6. doi: 10.1067/j.cpradiol.2019.07.001. [Epub ahead of print]


Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease.

Mato JM, Alonso C, Noureddin M, Lu SC.

World J Gastroenterol. 2019 Jun 28;25(24):3009-3020. doi: 10.3748/wjg.v25.i24.3009. Review.


Synthesis of the Tricyclic Caged Core of Palhinine Alkaloids Based on a Non-Diels-Alder-Type Strategy.

Lu SC, Liang YY, Li L, Wang XL, Zhang SP, Gong YL, Xu S.

Org Lett. 2019 Jul 19;21(14):5567-5569. doi: 10.1021/acs.orglett.9b01898. Epub 2019 Jun 26.


Utility of MRI in Management of a Rare Case of Unilateral Dichorionic-Diamniotic Twin Tubal Ectopic Pregnancy.

Nepal P, Ojili V, Lu SC, Nagar A.

Curr Probl Diagn Radiol. 2019 Jun 8. pii: S0363-0188(19)30142-2. doi: 10.1067/j.cpradiol.2019.06.001. [Epub ahead of print]


Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.

Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E.

Sci Transl Med. 2019 Jun 12;11(496). pii: eaat9284. doi: 10.1126/scitranslmed.aat9284.


The Effect of Splenectomy on the Reversal of Cirrhosis: a Prospective Study.

Zeng DB, Di L, Zhang RC, Guo QL, Duan BW, Jia CY, Chen F, Lin DD, Zang YJ, Lu SC.

Gastroenterol Res Pract. 2019 Apr 8;2019:5459427. doi: 10.1155/2019/5459427. eCollection 2019.


Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression.

Murray B, Peng H, Barbier-Torres L, Robinson AE, Li TWH, Fan W, Tomasi ML, Gottlieb RA, Van Eyk J, Lu Z, Martínez-Chantar ML, Liangpunsakul S, Skill NJ, Mato JM, Lu SC.

Hepatology. 2019 May 11. doi: 10.1002/hep.30762. [Epub ahead of print]


NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.

Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, Bhowmick N, Seki E.

Hepatology. 2019 Nov;70(5):1582-1599. doi: 10.1002/hep.30693. Epub 2019 May 23.


Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease.

Ho CM, Ho SL, Jeng YM, Lai YS, Chen YH, Lu SC, Chen HL, Chang PY, Hu RH, Lee PH.

J Inflamm (Lond). 2019 Apr 2;16:7. doi: 10.1186/s12950-019-0211-5. eCollection 2019.


Assessment of the effect of the Aquamantys® system on local recurrence after hepatectomy for hepatocellular carcinoma through propensity score matching.

Sui MH, Wang HG, Chen MY, Wan T, Hu BY, Pan YW, Li H, Cai HY, Cui C, Lu SC.

Clin Transl Oncol. 2019 Dec;21(12):1634-1643. doi: 10.1007/s12094-019-02092-0. Epub 2019 Mar 25.


Clinical association between the metabolite of healthy gut microbiota, 3-indolepropionic acid and chronic kidney disease.

Sun CY, Lin CJ, Pan HC, Lee CC, Lu SC, Hsieh YT, Huang SY, Huang HY.

Clin Nutr. 2019 Dec;38(6):2945-2948. doi: 10.1016/j.clnu.2018.11.029. Epub 2018 Dec 27.


Treatment with methyl-β-cyclodextrin prevents mechanical allodynia in resiniferatoxin neuropathy in a mouse model.

Lin CL, Chang CH, Chang YS, Lu SC, Hsieh YL.

Biol Open. 2019 Jan 14;8(1). pii: bio039511. doi: 10.1242/bio.039511.


Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models.

Killion EA, Wang J, Yie J, Shi SD, Bates D, Min X, Komorowski R, Hager T, Deng L, Atangan L, Lu SC, Kurzeja RJM, Sivits G, Lin J, Chen Q, Wang Z, Thibault SA, Abbott CM, Meng T, Clavette B, Murawsky CM, Foltz IN, Rottman JB, Hale C, Véniant MM, Lloyd DJ.

Sci Transl Med. 2018 Dec 19;10(472). pii: eaat3392. doi: 10.1126/scitranslmed.aat3392.


Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated-Beta-Catenin Signaling in Murine Liver and Human Liver Cancer Cells.

Mavila N, Tang Y, Berlind J, Ramani K, Wang J, Mato JM, Lu SC.

Hepatol Commun. 2018 Sep 27;2(12):1583-1600. doi: 10.1002/hep4.1257. eCollection 2018 Dec.


The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.

Yang JW, Murray B, Barbier-Torres L, Liu T, Liu Z, Yang H, Fan W, Wang J, Li Y, Seki E, Mato JM, Lu SC.

J Biol Chem. 2019 Feb 8;294(6):1984-1996. doi: 10.1074/jbc.RA118.004863. Epub 2018 Dec 6.


Combination of PhI(OAc)2 and 2-Nitropropane as the Source of Methyl Radical in Room-Temperature Metal-Free Oxidative Decarboxylation/Cyclization: Construction of 6-Methyl Phenanthridines and 1-Methyl Isoquinolines.

Lu SC, Li HS, Gong YL, Zhang SP, Zhang JG, Xu S.

J Org Chem. 2018 Dec 21;83(24):15415-15425. doi: 10.1021/acs.joc.8b02701. Epub 2018 Dec 12.


MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis.

Fernández-Ramos D, Fernández-Tussy P, Lopitz-Otsoa F, Gutiérrez-de-Juan V, Navasa N, Barbier-Torres L, Zubiete-Franco I, Simón J, Fernández AF, Arbelaiz A, Aransay AM, Lavín JL, Beraza N, Perugorria MJ, Banales JM, Villa E, Fraga MF, Anguita J, Avila MA, Berasain C, Iruzibieta P, Crespo J, Lu SC, Varela-Rey M, Mato JM, Delgado TC, Martínez-Chantar ML.

Cell Death Dis. 2018 Sep 20;9(10):958. doi: 10.1038/s41419-018-1014-y.


A novel experimental design for the measurement of metacarpal bone loading and deformation and fingertip force.

Lu SC, Vereecke EE, Synek A, Pahr DH, Kivell TL.

PeerJ. 2018 Sep 11;6:e5480. doi: 10.7717/peerj.5480. eCollection 2018.


Liver cancer-associated changes to the proteome: what deserves clinical focus?

Mato JM, Elortza F, Lu SC, Brun V, Paradela A, Corrales FJ.

Expert Rev Proteomics. 2018 Sep;15(9):749-756. doi: 10.1080/14789450.2018.1521277. Epub 2018 Sep 19. Review.


Tumor necrosis factor-α mediated pain hypersensitivity through Ret receptor in resiniferatoxin neuropathy.

Lu SC, Chang YS, Kan HW, Hsieh YL.

Kaohsiung J Med Sci. 2018 Sep;34(9):494-502. doi: 10.1016/j.kjms.2018.04.008.


Au@CdSe heteroepitaxial nanorods: An example of metal nanorods fully covered by a semiconductor shell with strong photo-induced interfacial charge transfer effects.

Lim SC, Lo WF, Yang PY, Lu SC, Joplin A, Link S, Chang WS, Tuan HY.

J Colloid Interface Sci. 2018 Dec 15;532:143-152. doi: 10.1016/j.jcis.2018.07.080. Epub 2018 Jul 20.


Toxic epidermal necrosis induced by carbamazepine embedded in the subcutis.

Liu JJ, Lu SC, Liu JL, Yang HM.

An Bras Dermatol. 2018 Jul-Aug;93(4):620-621. doi: 10.1590/abd1806-4841.20187725. No abstract available.


Metabolomic-based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts.

Mayo R, Crespo J, Martínez-Arranz I, Banales JM, Arias M, Mincholé I, Aller de la Fuente R, Jimenez-Agüero R, Alonso C, de Luis DA, Vitek L, Stritesky J, Caballería J, Romero-Gómez M, Martín-Duce A, Mugüerza Huguet JM, Busteros-Moraza JI, Idowu MO, Castro A, Martínez-Chantar ML, Ortiz P, Bruha R, Lu SC, Bedossa P, Noureddin M, Sanyal AJ, Mato JM.

Hepatol Commun. 2018 May 4;2(7):807-820. doi: 10.1002/hep4.1188. eCollection 2018 Jul.


NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances.

Noureddin M, Vipani A, Bresee C, Todo T, Kim IK, Alkhouri N, Setiawan VW, Tran T, Ayoub WS, Lu SC, Klein AS, Sundaram V, Nissen NN.

Am J Gastroenterol. 2018 Nov;113(11):1649-1659. doi: 10.1038/s41395-018-0088-6. Epub 2018 Jun 8.


Usefulness of three-dimensional visualization technology in minimally invasive treatment for infected necrotizing pancreatitis.

Wang PF, Liu ZW, Cai SW, Su JJ, He L, Feng J, Xin XL, Lu SC.

World J Gastroenterol. 2018 May 7;24(17):1911-1918. doi: 10.3748/wjg.v24.i17.1911.


Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.

Liu T, Yang H, Fan W, Tu J, Li TWH, Wang J, Shen H, Yang J, Xiong T, Steggerda J, Liu Z, Noureddin M, Maldonado SS, Annamalai A, Seki E, Mato JM, Lu SC.

Gastroenterology. 2018 Aug;155(2):557-571.e14. doi: 10.1053/j.gastro.2018.04.032. Epub 2018 May 5.


Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals.

Noureddin M, Wong MM, Todo T, Lu SC, Sanyal AJ, Mena EA.

World J Gastroenterol. 2018 Mar 21;24(11):1269-1277. doi: 10.3748/wjg.v24.i11.1269.


A study on risk factors and diagnostic efficiency of posthepatectomy liver failure in the nonobstructive jaundice.

Wang H, Lu SC, He L, Dong JH.

Medicine (Baltimore). 2018 Feb;97(8):e9963. doi: 10.1097/MD.0000000000009963.


Homocysteine is a bystander for ST-segment elevation myocardial infarction: a case-control study.

Chen CJ, Yang TC, Chang C, Lu SC, Chang PY.

BMC Cardiovasc Disord. 2018 Feb 13;18(1):33. doi: 10.1186/s12872-018-0774-8.


[Travel Preparations for Patients Receiving Peritoneal Dialysis].

Lu SC, Lin WC.

Hu Li Za Zhi. 2018 Feb;65(1):90-95. doi: 10.6224/JN.201802_65(1).12. Chinese.


The Study of Smartphone Usage Competency Assessment and Training for the Elderly.

Lu SC, Wen TN, Chang PL.

Stud Health Technol Inform. 2017;245:161-165.


The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.

Barbier-Torres L, Iruzubieta P, Fernández-Ramos D, Delgado TC, Taibo D, Guitiérrez-de-Juan V, Varela-Rey M, Azkargorta M, Navasa N, Fernández-Tussy P, Zubiete-Franco I, Simon J, Lopitz-Otsoa F, Lachiondo-Ortega S, Crespo J, Masson S, McCain MV, Villa E, Reeves H, Elortza F, Lucena MI, Hernández-Alvarez MI, Zorzano A, Andrade RJ, Lu SC, Mato JM, Anguita J, Rincón M, Martínez-Chantar ML.

Nat Commun. 2017 Dec 12;8(1):2068. doi: 10.1038/s41467-017-01970-x.


Methionine adenosyltransferases in liver health and diseases.

Ramani K, Lu SC.

Liver Res. 2017 Sep;1(2):103-111. doi: 10.1016/j.livres.2017.07.002.


Role of Aramchol in steatohepatitis and fibrosis in mice.

Iruarrizaga-Lejarreta M, Varela-Rey M, Fernández-Ramos D, Martínez-Arranz I, Delgado TC, Simon J, Juan VG, delaCruz-Villar L, Azkargorta M, Lavin JL, Mayo R, Van Liempd SM, Aurrekoetxea I, Buqué X, Cave DD, Peña A, Rodríguez-Cuesta J, Aransay AM, Elortza F, Falcón-Pérez JM, Aspichueta P, Hayardeny L, Noureddin M, Sanyal AJ, Alonso C, Anguita J, Martínez-Chantar ML, Lu SC, Mato JM.

Hepatol Commun. 2017 Nov;1(9):911-927. doi: 10.1002/hep4.1107. Epub 2017 Oct 4.


Methionine adenosyltransferases in cancers: Mechanisms of dysregulation and implications for therapy.

Maldonado LY, Arsene D, Mato JM, Lu SC.

Exp Biol Med (Maywood). 2018 Jan;243(2):107-117. doi: 10.1177/1535370217740860. Epub 2017 Nov 15. Review.


S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis.

Tomasi ML, Cossu C, Spissu Y, Floris A, Ryoo M, Iglesias-Ara A, Wang Q, Pandol SJ, Bhowmick NA, Seki E, Posadas EM, Lu SC.

Oncotarget. 2017 Aug 12;8(45):78851-78869. doi: 10.18632/oncotarget.20234. eCollection 2017 Oct 3.


Electronegative L5-LDL induces the production of G-CSF and GM-CSF in human macrophages through LOX-1 involving NF-κB and ERK2 activation.

Yang TC, Chang PY, Kuo TL, Lu SC.

Atherosclerosis. 2017 Dec;267:1-9. doi: 10.1016/j.atherosclerosis.2017.10.016. Epub 2017 Oct 14.


Serum levels of uncoupling proteins in patients with differential insulin resistance: A community-based cohort study.

Pan HC, Lee CC, Chou KM, Lu SC, Sun CY.

Medicine (Baltimore). 2017 Oct;96(40):e8053. doi: 10.1097/MD.0000000000008053.


Postoperative inflammation as a possible cause of portal vein thrombosis after irreversible electroporation for locally advanced pancreatic cancer.

Su JJ, Su M, Xu K, Wang PF, Yan L, Lu SC, Gu WQ, Chen YL.

World J Gastroenterol. 2017 Aug 28;23(32):6003-6006. doi: 10.3748/wjg.v23.i32.6003. Review.


Effects of Carpal Tunnel Syndrome on Force Coordination and Muscle Coherence during Precision Pinch.

Lu SC, Xiu K, Li K, Marquardt TL, Evans PJ, Li ZM.

J Med Biol Eng. 2017 Jun;37(3):328-335. doi: 10.1007/s40846-017-0232-6. Epub 2017 Mar 24.

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