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Items: 1 to 50 of 116

1.

Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice.

Vila MC, Novak JS, Benny Klimek M, Li N, Morales M, Fritz AG, Edwards K, Boehler JF, Hogarth MW, Kinder TB, Zhang A, Mazala D, Fiorillo AA, Douglas B, Chen YW, van den Anker J, Lu QL, Hathout Y, Hoffman EP, Partridge TA, Nagaraju K.

J Pathol. 2019 Jul;248(3):339-351. doi: 10.1002/path.5263. Epub 2019 Apr 16.

PMID:
30883742
2.

Comparison of Efficacy between 3D Navigation-Assisted Percutaneous Iliosacral Screw and Minimally Invasive Reconstruction Plate in Treating Sacroiliac Complex Injury.

Lu QL, Zhu YL, Li XG, Xie W, Wang XZ, Shao XZ, Cai XH, Liu XM.

Curr Med Sci. 2019 Feb;39(1):81-87. doi: 10.1007/s11596-019-2003-9. Epub 2019 Mar 13.

PMID:
30868495
3.

Vinpocetine in the treatment of poststroke cognitive dysfunction: A protocol for systematic review and meta-analysis.

Liu Y, Yin Y, Lu QL, Dan Y, Xu MS, Song G, Li C.

Medicine (Baltimore). 2019 Feb;98(6):e13685. doi: 10.1097/MD.0000000000013685. Review.

4.

Dose-Dependent Effects of FKRP Gene-Replacement Therapy on Functional Rescue and Longevity in Dystrophic Mice.

Vannoy CH, Leroy V, Lu QL.

Mol Ther Methods Clin Dev. 2018 Oct 13;11:106-120. doi: 10.1016/j.omtm.2018.10.004. eCollection 2018 Dec 14.

5.

In Vivo Evaluation of Dystrophin Exon Skipping in mdx Mice.

Wu B, Wang M, Shah S, Lu QL.

Methods Mol Biol. 2018;1828:231-247. doi: 10.1007/978-1-4939-8651-4_14.

PMID:
30171545
6.

Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice.

Cataldi MP, Lu P, Blaeser A, Lu QL.

Nat Commun. 2018 Aug 27;9(1):3448. doi: 10.1038/s41467-018-05990-z.

7.

Substrate-Controlled Generation of 3-Sulfonylated 1-Indenones and 3-Arylated ( Z)-Indenes via Cu-Catalyzed Radical Cyclization Cascades of o-Alkynylbenzonitriles.

Zhu XT, Lu QL, Wang X, Zhang TS, Hao WJ, Tu SJ, Jiang B.

J Org Chem. 2018 Sep 7;83(17):9890-9901. doi: 10.1021/acs.joc.8b01343. Epub 2018 Aug 23.

PMID:
30106298
8.

[Prevalence and risk factors of diabetes and prediabetes in adults in Jingyuan Ningxia].

Chen SY, Wang T, Hou XH, Qian Y, Zhang HD, Lu QL, Liang YB, He LJ, Jia WP.

Zhonghua Nei Ke Za Zhi. 2018 Jul 1;57(7):500-504. doi: 10.3760/cma.j.issn.0578-1426.2018.07.006. Chinese.

PMID:
29996268
9.

Overexpression of Mutant FKRP Restores Functional Glycosylation and Improves Dystrophic Phenotype in FKRP Mutant Mice.

Tucker JD, Lu PJ, Xiao X, Lu QL.

Mol Ther Nucleic Acids. 2018 Jun 1;11:216-227. doi: 10.1016/j.omtn.2018.02.008. Epub 2018 Mar 6.

10.

Skeletal, cardiac, and respiratory muscle function and histopathology in the P448Lneo- mouse model of FKRP-deficient muscular dystrophy.

Yu Q, Morales M, Li N, Fritz AG, Ruobing R, Blaeser A, Francois E, Lu QL, Nagaraju K, Spurney CF.

Skelet Muscle. 2018 Apr 6;8(1):13. doi: 10.1186/s13395-018-0158-x.

11.

Long-Term Treatment of Tamoxifen and Raloxifene Alleviates Dystrophic Phenotype and Enhances Muscle Functions of FKRP Dystroglycanopathy.

Wu B, Shah SN, Lu P, Bollinger LE, Blaeser A, Sparks S, Harper AD, Lu QL.

Am J Pathol. 2018 Apr;188(4):1069-1080. doi: 10.1016/j.ajpath.2017.12.011.

PMID:
29571322
12.

Distinct expression of functionally glycosylated alpha-dystroglycan in muscle and non-muscle tissues of FKRP mutant mice.

Blaeser A, Awano H, Lu P, Lu QL.

PLoS One. 2018 Jan 10;13(1):e0191016. doi: 10.1371/journal.pone.0191016. eCollection 2018.

13.

Planarization of B20 clusters by Si and C atom substitution.

Lu QL, Luo QQ, Li Y, Huang SG.

Phys Chem Chem Phys. 2017 Oct 25;19(41):28434-28438. doi: 10.1039/c7cp05610a.

PMID:
29038810
14.

[The prevalence of metabolic syndrome among adults in rural areas of Ningxia Hui autonomous region].

Wang T, Zhang HD, Lu QL, Xue HL, Wang FX, Ma Z, Wang JL, Li XW, Yu XF, Hou XH, Sun QY, Jia WP, He LJ.

Zhonghua Nei Ke Za Zhi. 2017 Jun 1;56(6):409-413. doi: 10.3760/cma.j.issn.0578-1426.2017.06.005. Chinese.

PMID:
28592039
15.

Efficacy of Gene Therapy Is Dependent on Disease Progression in Dystrophic Mice with Mutations in the FKRP Gene.

Vannoy CH, Xiao W, Lu P, Xiao X, Lu QL.

Mol Ther Methods Clin Dev. 2017 Mar 8;5:31-42. doi: 10.1016/j.omtm.2017.02.002. eCollection 2017 Jun 16.

16.

Topochemical synthesis and photocatalytic activity of 3D hierarchical BaTiO3 microspheres constructed from crystal-axis-oriented nanosheets.

Chen CK, Zhao SX, Lu QL, Luo K, Zhang XH, Nan CW.

Dalton Trans. 2017 Apr 11;46(15):5017-5024. doi: 10.1039/c7dt00724h.

PMID:
28350023
17.

Adeno-Associated Virus-Mediated Mini-Agrin Delivery Is Unable to Rescue Disease Phenotype in a Mouse Model of Limb Girdle Muscular Dystrophy Type 2I.

Vannoy CH, Zhou H, Qiao C, Xiao X, Bang AG, Lu QL.

Am J Pathol. 2017 Feb;187(2):431-440. doi: 10.1016/j.ajpath.2016.09.024.

PMID:
28107841
18.

Association of genetic variations in miR-146a rs2910164 and miR-149 rs11614913 with the development of classic Kaposi sarcoma.

Yang H, Lu QL, Wu XJ, Ma HY, Qu YY, Zhang DZ, Pu XM.

Genet Mol Res. 2016 Nov 3;15(4). doi: 10.4238/gmr15048855.

PMID:
27819716
19.

Progressive Dystrophic Pathology in Diaphragm and Impairment of Cardiac Function in FKRP P448L Mutant Mice.

Blaeser A, Awano H, Wu B, Lu QL.

PLoS One. 2016 Oct 6;11(10):e0164187. doi: 10.1371/journal.pone.0164187. eCollection 2016.

20.

Trendelenburg-Like Gait, Instability and Altered Step Patterns in a Mouse Model for Limb Girdle Muscular Dystrophy 2i.

Maricelli JW, Lu QL, Lin DC, Rodgers BD.

PLoS One. 2016 Sep 14;11(9):e0161984. doi: 10.1371/journal.pone.0161984. eCollection 2016.

21.

Preventive effects of cedrol against alopecia in cyclophosphamide-treated mice.

Chen SS, Zhang Y, Lu QL, Lin Z, Zhao Y.

Environ Toxicol Pharmacol. 2016 Sep;46:270-276. doi: 10.1016/j.etap.2016.07.020. Epub 2016 Jul 30.

PMID:
27522546
22.

Expression of glycosylated α-dystroglycan in newborn skeletal and cardiac muscles of fukutin related protein (FKRP) mutant mice.

Keramaris E, Lu PJ, Tucker J, Lu QL.

Muscle Nerve. 2017 Apr;55(4):582-590. doi: 10.1002/mus.25378. Epub 2016 Dec 30.

PMID:
27515093
23.

Analysis of the Structures and Properties of (GaSb)n (n = 4-9) Clusters through Density Functional Theory.

Lu QL, Luo QQ, Huang SG, Li YD, Wan JG.

J Phys Chem A. 2016 Jul 7;120(26):4560-4. doi: 10.1021/acs.jpca.6b05529. Epub 2016 Jun 27.

PMID:
27322830
24.

Glucocorticoid Steroid and Alendronate Treatment Alleviates Dystrophic Phenotype with Enhanced Functional Glycosylation of α-Dystroglycan in Mouse Model of Limb-Girdle Muscular Dystrophy with FKRPP448L Mutation.

Wu B, Shah SN, Lu P, Richardson SM, Bollinger LE, Blaeser A, Madden KL, Sun Y, Luckie TM, Cox MD, Sparks S, Harper AD, Lu QL.

Am J Pathol. 2016 Jun;186(6):1635-48. doi: 10.1016/j.ajpath.2016.02.015. Epub 2016 Apr 22.

PMID:
27109613
25.

Ginsenoside-Rd Promotes Neurite Outgrowth of PC12 Cells through MAPK/ERK- and PI3K/AKT-Dependent Pathways.

Wu SD, Xia F, Lin XM, Duan KL, Wang F, Lu QL, Cao H, Qian YH, Shi M.

Int J Mol Sci. 2016 Jan 29;17(2). pii: E177. doi: 10.3390/ijms17020177.

26.

Elusive sources of variability of dystrophin rescue by exon skipping.

Vila MC, Klimek MB, Novak JS, Rayavarapu S, Uaesoontrachoon K, Boehler JF, Fiorillo AA, Hogarth MW, Zhang A, Shaughnessy C, Gordish-Dressman H, Burki U, Straub V, Lu QL, Partridge TA, Brown KJ, Hathout Y, van den Anker J, Hoffman EP, Nagaraju K.

Skelet Muscle. 2015 Dec 1;5:44. doi: 10.1186/s13395-015-0070-6. eCollection 2015.

27.

DFT study on endohedral and exohedral B38 fullerenes: M@B38 (M = Sc, Y, Ti) and M&B38 (M = Nb, Fe, Co, Ni).

Lu QL, Luo QQ, Li YD, Huang SG.

Phys Chem Chem Phys. 2015 Aug 28;17(32):20897-902. doi: 10.1039/c5cp03378k. Epub 2015 Jul 27.

PMID:
26214310
28.

Restoration of Functional Glycosylation of α-Dystroglycan in FKRP Mutant Mice Is Associated with Muscle Regeneration.

Awano H, Blaeser A, Keramaris E, Xu L, Tucker J, Wu B, Lu P, Lu QL.

Am J Pathol. 2015 Jul;185(7):2025-37. doi: 10.1016/j.ajpath.2015.03.017. Epub 2015 May 12.

PMID:
25976249
29.

Effective Resistance to Wheat Stripe Rust in a Region with High Disease Pressure.

Bai B, Du JY, Lu QL, He CY, Zhang LJ, Zhou G, Xia XC, He ZH, Wang CS.

Plant Dis. 2014 Jul;98(7):891-897. doi: 10.1094/PDIS-09-13-0909-RE.

PMID:
30708850
30.

Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice.

Wu B, Cloer C, Lu P, Milazi S, Shaban M, Shah SN, Marston-Poe L, Moulton HM, Lu QL.

Gene Ther. 2014 Sep;21(9):785-93. doi: 10.1038/gt.2014.53. Epub 2014 Jun 19.

31.

Expression of nerve growth factor and hypoxia inducible factor-1α and its correlation with angiogenesis in non-small cell lung cancer.

Lu QL, Liu J, Zhu XL, Xu WJ.

J Huazhong Univ Sci Technolog Med Sci. 2014 Jun;34(3):359-362. doi: 10.1007/s11596-014-1283-3. Epub 2014 Jun 18.

PMID:
24939299
32.

Adeno-associated virus-mediated overexpression of LARGE rescues α-dystroglycan function in dystrophic mice with mutations in the fukutin-related protein.

Vannoy CH, Xu L, Keramaris E, Lu P, Xiao X, Lu QL.

Hum Gene Ther Methods. 2014 Jun;25(3):187-96. doi: 10.1089/hgtb.2013.151. Epub 2014 May 2.

33.

What Can We Learn From Clinical Trials of Exon Skipping for DMD?

Lu QL, Cirak S, Partridge T.

Mol Ther Nucleic Acids. 2014 Mar 11;3:e152. doi: 10.1038/mtna.2014.6. No abstract available.

34.

Evaluation of Tris[2-(acryloyloxy)ethyl]isocyanurate cross-linked polyethylenimine as antisense morpholino oligomer delivery vehicle in cell culture and dystrophic mdx mice.

Wang M, Wu B, Tucker JD, Lu P, Cloer C, Lu QL.

Hum Gene Ther. 2014 May;25(5):419-27. doi: 10.1089/hum.2013.156. Epub 2014 Apr 25.

35.

Pluronic-PEI copolymers enhance exon-skipping of 2'-O-methyl phosphorothioate oligonucleotide in cell culture and dystrophic mdx mice.

Wang M, Wu B, Lu P, Tucker JD, Milazi S, Shah SN, Lu QL.

Gene Ther. 2014 Jan;21(1):52-9. doi: 10.1038/gt.2013.57. Epub 2013 Oct 17.

PMID:
24131982
36.

Adeno-associated virus 9 mediated FKRP gene therapy restores functional glycosylation of α-dystroglycan and improves muscle functions.

Xu L, Lu PJ, Wang CH, Keramaris E, Qiao C, Xiao B, Blake DJ, Xiao X, Lu QL.

Mol Ther. 2013 Oct;21(10):1832-40. doi: 10.1038/mt.2013.156. Epub 2013 Jul 2.

37.

Mouse models of fukutin-related protein mutations show a wide range of disease phenotypes.

Blaeser A, Keramaris E, Chan YM, Sparks S, Cowley D, Xiao X, Lu QL.

Hum Genet. 2013 Aug;132(8):923-34. doi: 10.1007/s00439-013-1302-7. Epub 2013 Apr 17.

PMID:
23591631
38.

Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy.

Kendall GC, Mokhonova EI, Moran M, Sejbuk NE, Wang DW, Silva O, Wang RT, Martinez L, Lu QL, Damoiseaux R, Spencer MJ, Nelson SF, Miceli MC.

Sci Transl Med. 2012 Dec 12;4(164):164ra160. doi: 10.1126/scitranslmed.3005054.

39.

Theoretical study on aluminum carbide endohedral fullerene-Al4C@C80.

Lu QL, Song WJ, Meng JW, Wan JG.

J Mol Model. 2013 Mar;19(3):1205-9. doi: 10.1007/s00894-012-1665-z. Epub 2012 Nov 17.

PMID:
23160935
40.

Tumor-infiltrating regulatory T cells are positively correlated with angiogenic status in renal cell carcinoma.

Ning H, Shao QQ, Ding KJ, Gao DX, Lu QL, Cao QW, Niu ZH, Fu Q, Zhang CH, Qu X, Lü JJ.

Chin Med J (Engl). 2012 Jun;125(12):2120-5.

PMID:
22884140
41.

Ultrastructural remodelling of Ca(2+) signalling apparatus in failing heart cells.

Wu HD, Xu M, Li RC, Guo L, Lai YS, Xu SM, Li SF, Lü QL, Li LL, Zhang HB, Zhang YY, Zhang CM, Wang SQ.

Cardiovasc Res. 2012 Sep 1;95(4):430-8. doi: 10.1093/cvr/cvs195. Epub 2012 Jun 15.

42.

Long-term rescue of dystrophin expression and improvement in muscle pathology and function in dystrophic mdx mice by peptide-conjugated morpholino.

Wu B, Lu P, Cloer C, Shaban M, Grewal S, Milazi S, Shah SN, Moulton HM, Lu QL.

Am J Pathol. 2012 Aug;181(2):392-400. doi: 10.1016/j.ajpath.2012.04.006. Epub 2012 Jun 7.

43.

Systemic delivery of antisense oligomer in animal models and its implications for treating DMD.

Lu QL, Wu B.

Methods Mol Biol. 2012;867:393-405. doi: 10.1007/978-1-61779-767-5_25.

PMID:
22454075
44.

Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.

Kuga A, Kanagawa M, Sudo A, Chan YM, Tajiri M, Manya H, Kikkawa Y, Nomizu M, Kobayashi K, Endo T, Lu QL, Wada Y, Toda T.

J Biol Chem. 2012 Mar 16;287(12):9560-7. doi: 10.1074/jbc.M111.271767. Epub 2012 Jan 23.

45.

Targeted skipping of human dystrophin exons in transgenic mouse model systemically for antisense drug development.

Wu B, Benrashid E, Lu P, Cloer C, Zillmer A, Shaban M, Lu QL.

PLoS One. 2011;6(5):e19906. doi: 10.1371/journal.pone.0019906. Epub 2011 May 17.

46.

Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population.

Wang F, Xu CQ, He Q, Cai JP, Li XC, Wang D, Xiong X, Liao YH, Zeng QT, Yang YZ, Cheng X, Li C, Yang R, Wang CC, Wu G, Lu QL, Bai Y, Huang YF, Yin D, Yang Q, Wang XJ, Dai DP, Zhang RF, Wan J, Ren JH, Li SS, Zhao YY, Fu FF, Huang Y, Li QX, Shi SW, Lin N, Pan ZW, Li Y, Yu B, Wu YX, Ke YH, Lei J, Wang N, Luo CY, Ji LY, Gao LJ, Li L, Liu H, Huang EW, Cui J, Jia N, Ren X, Li H, Ke T, Zhang XQ, Liu JY, Liu MG, Xia H, Yang B, Shi LS, Xia YL, Tu X, Wang QK.

Nat Genet. 2011 Mar 6;43(4):345-9. doi: 10.1038/ng.783.

PMID:
21378986
47.

[Variation analysis on the grain yield and main agronomic traits of spring wheat in rainfed regions of China].

Chang L, Chai SX, Yang DL, Lu QL.

Ying Yong Sheng Tai Xue Bao. 2010 Nov;21(11):2821-9. Chinese.

PMID:
21361005
48.

AtFH8 is involved in root development under effect of low-dose latrunculin B in dividing cells.

Xue XH, Guo CQ, Du F, Lu QL, Zhang CM, Ren HY.

Mol Plant. 2011 Mar;4(2):264-78. doi: 10.1093/mp/ssq085. Epub 2011 Feb 9.

49.

One-year treatment of morpholino antisense oligomer improves skeletal and cardiac muscle functions in dystrophic mdx mice.

Wu B, Xiao B, Cloer C, Shaban M, Sali A, Lu P, Li J, Nagaraju K, Xiao X, Lu QL.

Mol Ther. 2011 Mar;19(3):576-83. doi: 10.1038/mt.2010.288. Epub 2010 Dec 21.

50.

The status of exon skipping as a therapeutic approach to duchenne muscular dystrophy.

Lu QL, Yokota T, Takeda S, Garcia L, Muntoni F, Partridge T.

Mol Ther. 2011 Jan;19(1):9-15. doi: 10.1038/mt.2010.219. Epub 2010 Oct 26. Review.

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