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Items: 16

1.

The CXCL12/CXCR4 Signaling Axis Retains Neutrophils at Inflammatory Sites in Zebrafish.

Isles HM, Herman KD, Robertson AL, Loynes CA, Prince LR, Elks PM, Renshaw SA.

Front Immunol. 2019 Jul 31;10:1784. doi: 10.3389/fimmu.2019.01784. eCollection 2019.

2.

15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.

Evans RJ, Pline K, Loynes CA, Needs S, Aldrovandi M, Tiefenbach J, Bielska E, Rubino RE, Nicol CJ, May RC, Krause HM, O'Donnell VB, Renshaw SA, Johnston SA.

PLoS Pathog. 2019 Mar 28;15(3):e1007597. doi: 10.1371/journal.ppat.1007597. eCollection 2019 Mar.

3.

PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo.

Loynes CA, Lee JA, Robertson AL, Steel MJ, Ellett F, Feng Y, Levy BD, Whyte MKB, Renshaw SA.

Sci Adv. 2018 Sep 5;4(9):eaar8320. doi: 10.1126/sciadv.aar8320. eCollection 2018 Sep.

4.

Expression and regulation of drug transporters in vertebrate neutrophils.

Foulkes MJ, Henry KM, Rougeot J, Hooper-Greenhill E, Loynes CA, Jeffrey P, Fleming A, Savage CO, Meijer AH, Jones S, Renshaw SA.

Sci Rep. 2017 Jul 10;7(1):4967. doi: 10.1038/s41598-017-04785-4.

5.

Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen.

Robertson AL, Ogryzko NV, Henry KM, Loynes CA, Foulkes MJ, Meloni MM, Wang X, Ford C, Jackson M, Ingham PW, Wilson HL, Farrow SN, Solari R, Flower RJ, Jones S, Whyte MK, Renshaw SA.

Dis Model Mech. 2016 Jun 1;9(6):621-32. doi: 10.1242/dmm.024935. Epub 2016 Apr 14.

6.

Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus.

Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, Surewaard B, Seneviratne SL, Grogono DM, Cachat J, Ny T, Kaser A, Török ME, Peacock SJ, Holden M, Blundell T, Wang L, Ligoxygakis P, Minichiello L, Woods CG, Foster SJ, Renshaw SA, Floto RA.

Science. 2014 Oct 31;346(6209):641-646. doi: 10.1126/science.1258705.

7.

A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism.

Robertson AL, Holmes GR, Bojarczuk AN, Burgon J, Loynes CA, Chimen M, Sawtell AK, Hamza B, Willson J, Walmsley SR, Anderson SR, Coles MC, Farrow SN, Solari R, Jones S, Prince LR, Irimia D, Rainger GE, Kadirkamanathan V, Whyte MK, Renshaw SA.

Sci Transl Med. 2014 Feb 26;6(225):225ra29. doi: 10.1126/scitranslmed.3007672.

8.

Zebrafish as a model for the study of neutrophil biology.

Henry KM, Loynes CA, Whyte MK, Renshaw SA.

J Leukoc Biol. 2013 Oct;94(4):633-42. doi: 10.1189/jlb.1112594. Epub 2013 Mar 5. Review.

PMID:
23463724
9.

A method for the in vivo measurement of zebrafish tissue neutrophil lifespan.

Dixon G, Elks PM, Loynes CA, Whyte MK, Renshaw SA.

ISRN Hematol. 2012;2012:915868. doi: 10.5402/2012/915868. Epub 2012 Jul 16.

10.

Measuring inflammatory cell migration in the zebrafish.

Elks PM, Loynes CA, Renshaw SA.

Methods Mol Biol. 2011;769:261-75. doi: 10.1007/978-1-61779-207-6_18.

PMID:
21748682
11.

Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish.

Gray C, Loynes CA, Whyte MK, Crossman DC, Renshaw SA, Chico TJ.

Thromb Haemost. 2011 May;105(5):811-9. doi: 10.1160/TH10-08-0525. Epub 2011 Jan 12.

12.

Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish.

Loynes CA, Martin JS, Robertson A, Trushell DM, Ingham PW, Whyte MK, Renshaw SA.

J Leukoc Biol. 2010 Feb;87(2):203-12. doi: 10.1189/jlb.0409255.

13.

Modeling inflammation in the zebrafish: how a fish can help us understand lung disease.

Renshaw SA, Loynes CA, Elworthy S, Ingham PW, Whyte MK.

Exp Lung Res. 2007 Dec;33(10):549-54. Review.

PMID:
18075830
14.

Unraveling tissue regeneration pathways using chemical genetics.

Mathew LK, Sengupta S, Kawakami A, Andreasen EA, Löhr CV, Loynes CA, Renshaw SA, Peterson RT, Tanguay RL.

J Biol Chem. 2007 Nov 30;282(48):35202-10. Epub 2007 Sep 11.

15.

A transgenic zebrafish model of neutrophilic inflammation.

Renshaw SA, Loynes CA, Trushell DM, Elworthy S, Ingham PW, Whyte MK.

Blood. 2006 Dec 15;108(13):3976-8. Epub 2006 Aug 22.

16.

Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.

Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, Barber SC, Loynes CA, Wood-Allum CA, Lunec J, Shaw PJ.

Brain. 2005 Jul;128(Pt 7):1686-706. Epub 2005 May 4.

PMID:
15872021

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