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Items: 1 to 50 of 119

1.

Statins as adjunctive therapy against tuberculosis:the balance between statin-induced anti-TB effect and trained immunity suppression.

Hu Z, Lowrie DB, Fan XY.

J Infect Dis. 2019 Dec 24. pii: jiz675. doi: 10.1093/infdis/jiz675. [Epub ahead of print] No abstract available.

PMID:
31873749
2.

Heterologous prime-boost vaccination against tuberculosis with recombinant Sendai virus and DNA vaccines.

Hu Z, Jiang W, Gu L, Qiao D, Shu T, Lowrie DB, Lu SH, Fan XY.

J Mol Med (Berl). 2019 Dec;97(12):1685-1694. doi: 10.1007/s00109-019-01844-3. Epub 2019 Nov 30.

PMID:
31786669
3.

Reply to Tonby et al.

Hu Z, Lu SH, Lowrie DB, Fan XY.

J Infect Dis. 2019 Jun 5;220(1):176-178. doi: 10.1093/infdis/jiz057. No abstract available.

PMID:
30888027
4.

The predictive values of the tuberculin skin test and interferon-γ release assays for active tuberculosis development.

Hu Z, Lu SH, Lowrie DB, Fan XY.

Lancet Infect Dis. 2019 Jan;19(1):19-20. doi: 10.1016/S1473-3099(18)30712-6. No abstract available.

PMID:
30587284
5.

Differential T cell responses against DosR-associated antigen Rv2028c in BCG-vaccinated populations with tuberculosis infection.

Zhao HM, Du R, Li CL, Ji P, Li HC, Wu K, Hu Z, Lu SH, Lowrie DB, Fan XY.

J Infect. 2019 Apr;78(4):275-280. doi: 10.1016/j.jinf.2018.10.016. Epub 2018 Dec 5.

PMID:
30528871
6.

The Profile of T Cell Responses in Bacille Calmette-Guérin-Primed Mice Boosted by a Novel Sendai Virus Vectored Anti-Tuberculosis Vaccine.

Hu Z, Gu L, Li CL, Shu T, Lowrie DB, Fan XY.

Front Immunol. 2018 Aug 3;9:1796. doi: 10.3389/fimmu.2018.01796. eCollection 2018.

7.

Reply to Mahla.

Hu Z, Lowrie DB, Fan XY.

J Infect Dis. 2018 Sep 8;218(8):1348-1349. doi: 10.1093/infdis/jiy314. No abstract available.

PMID:
29846644
8.

The Role of KLRG1 in Human CD4+ T-Cell Immunity Against Tuberculosis.

Hu Z, Zhao HM, Li CL, Liu XH, Barkan D, Lowrie DB, Lu SH, Fan XY.

J Infect Dis. 2018 Apr 11;217(9):1491-1503. doi: 10.1093/infdis/jiy046.

PMID:
29373700
9.

Evaluation of a New IFN-γ Release Assay for Rapid Diagnosis of Active Tuberculosis in a High-Incidence Setting.

Li G, Li F, Zhao HM, Wen HL, Li HC, Li CL, Ji P, Xu P, Wu K, Hu ZD, Lu SH, Lowrie DB, Lv JX, Fan XY.

Front Cell Infect Microbiol. 2017 Apr 11;7:117. doi: 10.3389/fcimb.2017.00117. eCollection 2017.

10.

Involvement of methylated HBHA expressed from Mycobacterium smegmatis in an IFN-γ release assay to aid discrimination between latent infection and active tuberculosis in BCG-vaccinated populations.

Wen HL, Li CL, Li G, Lu YH, Li HC, Li T, Zhao HM, Wu K, Lowrie DB, Lv JX, Lu SH, Fan XY.

Eur J Clin Microbiol Infect Dis. 2017 Aug;36(8):1415-1423. doi: 10.1007/s10096-017-2948-1. Epub 2017 Apr 20.

PMID:
28429162
11.

Sendai Virus Mucosal Vaccination Establishes Lung-Resident Memory CD8 T Cell Immunity and Boosts BCG-Primed Protection against TB in Mice.

Hu Z, Wong KW, Zhao HM, Wen HL, Ji P, Ma H, Wu K, Lu SH, Li F, Li ZM, Shu T, Xu JQ, Lowrie DB, Fan XY.

Mol Ther. 2017 May 3;25(5):1222-1233. doi: 10.1016/j.ymthe.2017.02.018. Epub 2017 Mar 23.

12.

The Numerical Predominance and Large Transcriptome Differences of Neutrophils in Peripheral Blood Together Inevitably Account for a Reported Pulmonary Tuberculosis Signature.

Wu K, Wong KW, Deng WL, Zhang H, Li J, Lowrie DB, Fan XY.

Int J Genomics. 2017;2017:5830971. doi: 10.1155/2017/5830971. Epub 2017 Feb 6.

13.

Boosting BCG-primed mice with chimeric DNA vaccine HG856A induces potent multifunctional T cell responses and enhanced protection against Mycobacterium tuberculosis.

Ji P, Hu ZD, Kang H, Yuan Q, Ma H, Wen HL, Wu J, Li ZM, Lowrie DB, Fan XY.

Immunol Res. 2016 Feb;64(1):64-72. doi: 10.1007/s12026-015-8674-9.

PMID:
26111521
14.

Diabetes tolerogenic vaccines targeting antigen-specific inflammation.

Geng S, Zhang H, Zhou X, He Y, Zhang X, Xie X, Li C, He Z, Yu Q, Zhong Y, Lowrie DB, Zheng G, Wang B.

Hum Vaccin Immunother. 2015;11(2):522-30. doi: 10.1080/21645515.2014.1004024. Review.

15.

A derived network-based interferon-related signature of human macrophages responding to Mycobacterium tuberculosis.

Wu K, Fang H, Lyu LD, Lowrie DB, Wong KW, Fan XY.

Biomed Res Int. 2014;2014:713071. doi: 10.1155/2014/713071. Epub 2014 Aug 31.

17.

Administration of mycobacterial Ag85A and IL-17A fusion protein attenuates airway inflammation in a murine model of asthma.

Jin R, Guo S, Wang MY, Li YH, Wu LX, Ma H, Lowrie DB, Fan XY, Zhang JH.

Int Immunopharmacol. 2013 Dec;17(4):1067-74.

PMID:
24455775
18.

Il17A autoantibody induced by recombinant protein Ag85A-Il17A.

Jin R, Guo S, Wu L, Fan X, Ma H, Lowrie DB, Zhang J.

Appl Biochem Biotechnol. 2013 Jan;169(2):502-10. doi: 10.1007/s12010-012-9994-z. Epub 2012 Dec 13.

PMID:
23239413
19.

Tuberculosis vaccine research in China.

Lowrie DB.

Emerg Microbes Infect. 2012 Jul;1(7):e7. doi: 10.1038/emi.2012.3. Epub 2012 Jul 25. Review.

20.

[Involvement of intron A into eukaryotic expression vector to improve immunogenicity of mycobacterial heat-shock protein 65 DNA vaccine in mice].

Wu J, Ma H, Fan XY, Qu Q, Luo YP, Lowrie DB.

Zhonghua Yu Fang Yi Xue Za Zhi. 2012 Jan;46(1):58-63. Chinese.

PMID:
22490142
21.

Incorporation of immunostimulatory motifs in the transcribed region of a plasmid DNA vaccine enhances Th1 immune responses and therapeutic effect against Mycobacterium tuberculosis in mice.

Wu J, Ma H, Qu Q, Zhou WJ, Luo YP, Thangaraj H, Lowrie DB, Fan XY.

Vaccine. 2011 Oct 13;29(44):7624-30. doi: 10.1016/j.vaccine.2011.08.020. Epub 2011 Aug 19.

PMID:
21856352
22.

Molecular cloning, identification and functional characterization of a novel intracellular Cu-Zn superoxide dismutase from the freshwater mussel Cristaria plicata.

Xu HH, Ma H, Hu BQ, Lowrie DB, Fan XY, Wen CG.

Fish Shellfish Immunol. 2010 Oct;29(4):615-22. doi: 10.1016/j.fsi.2010.06.013. Epub 2010 Jun 16.

PMID:
20561586
23.

DNA vaccination during TB treatment generates super-protective immunity.

Lowrie DB.

Gene Ther. 2005 Apr;12(7):557-8. No abstract available.

PMID:
18360951
24.

Beneficial effect of anti-interleukin-4 antibody when administered in a murine model of tuberculosis infection.

Roy E, Brennan J, Jolles S, Lowrie DB.

Tuberculosis (Edinb). 2008 May;88(3):197-202. Epub 2007 Dec 21.

PMID:
18096435
25.

Progress towards a new tuberculosis vaccine.

Lowrie DB, Silva CL, Tascon RE.

BioDrugs. 1998 Sep;10(3):201-13.

PMID:
18020596
26.

Current strategies in TB immunotherapy.

Roy E, Lowrie DB, Jolles SR.

Curr Mol Med. 2007 Jun;7(4):373-86. Review.

PMID:
17584077
27.

Immunotherapeutics for tuberculosis in experimental animals: is there a common pathway activated by effective protocols?

Rook GA, Lowrie DB, Hernàndez-Pando R.

J Infect Dis. 2007 Jul 15;196(2):191-8. Epub 2007 Jun 5. Review.

PMID:
17570105
28.

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives.

Stadthagen G, Jackson M, Charles P, Boudou F, Barilone N, Huerre M, Constant P, Liav A, Bottova I, Nigou J, Brando T, Puzo G, Daffé M, Benjamin P, Coade S, Buxton RS, Tascon RE, Rae A, Robertson BD, Lowrie DB, Young DB, Gicquel B, Griffin R.

Microbes Infect. 2006 Jul;8(8):2245-53. Epub 2006 May 30.

29.

DNA vaccines for therapy of tuberculosis: where are we now?

Lowrie DB.

Vaccine. 2006 Mar 15;24(12):1983-9. Epub 2005 Nov 16. Review.

PMID:
16316711
30.

Therapeutic efficacy of high-dose intravenous immunoglobulin in Mycobacterium tuberculosis infection in mice.

Roy E, Stavropoulos E, Brennan J, Coade S, Grigorieva E, Walker B, Dagg B, Tascon RE, Lowrie DB, Colston MJ, Jolles S.

Infect Immun. 2005 Sep;73(9):6101-9.

31.
32.

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.

Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD.

Tuberculosis (Edinb). 2005 Jan-Mar;85(1-2):29-38. Epub 2005 Jan 20.

PMID:
15687025
33.
34.
35.

RNA encoding the MPT83 antigen induces protective immune responses against Mycobacterium tuberculosis infection.

Xue T, Stavropoulos E, Yang M, Ragno S, Vordermeier M, Chambers M, Hewinson G, Lowrie DB, Colston MJ, Tascon RE.

Infect Immun. 2004 Nov;72(11):6324-9.

36.

CD4 T cells guarantee optimal competitive fitness of CD8 memory T cells.

Johansen P, Stamou P, Tascon RE, Lowrie DB, Stockinger B.

Eur J Immunol. 2004 Jan;34(1):91-7.

37.

Anti-mycobacterial immunity induced by a single injection of M. leprae Hsp65-encoding plasmid DNA in biodegradable microparticles.

Johansen P, Raynaud C, Yang M, Colston MJ, Tascon RE, Lowrie DB.

Immunol Lett. 2003 Dec 15;90(2-3):81-5.

PMID:
14687708
38.

DNA vaccination: an update.

Lowrie DB.

Methods Mol Med. 2003;87:377-90. Review. No abstract available.

PMID:
12958468
39.

A DNA prime-Mycobacterium bovis BCG boost vaccination strategy for cattle induces protection against bovine tuberculosis.

Skinner MA, Buddle BM, Wedlock DN, Keen D, de Lisle GW, Tascon RE, Ferraz JC, Lowrie DB, Cockle PJ, Vordermeier HM, Hewinson RG.

Infect Immun. 2003 Sep;71(9):4901-7.

40.

Improved immunogenicity of DNA vaccination with mycobacterial HSP65 against bovine tuberculosis by protein boosting.

Vordermeier HM, Lowrie DB, Hewinson RG.

Vet Microbiol. 2003 Jun 10;93(4):349-59.

PMID:
12713896
41.

DNA injection in combination with electroporation: a novel method for vaccination of farmed ruminants.

Tollefsen S, Vordermeier M, Olsen I, Storset AK, Reitan LJ, Clifford D, Lowrie DB, Wiker HG, Huygen K, Hewinson G, Mathiesen I, Tjelle TE.

Scand J Immunol. 2003 Mar;57(3):229-38.

42.
43.

DNA vaccines against tuberculosis.

Lowrie DB.

Curr Opin Mol Ther. 1999 Feb;1(1):30-3. Review.

PMID:
11249680
44.
45.

Enhancement of immunocompetence in tuberculosis by DNA vaccination.

Lowrie DB, Silva CL.

Vaccine. 2000 Feb 25;18(16):1712-6.

PMID:
10689154
46.
47.

Repeated use of qiagen columns in large-scale preparation of plasmid DNA.

Gregory D, Tascon RE, Lowrie DB.

Methods Mol Med. 2000;29:35-6. doi: 10.1385/1-59259-688-6:35.

PMID:
21374307
48.

Therapy of tuberculosis in mice by DNA vaccination.

Lowrie DB, Tascon RE, Bonato VL, Lima VM, Faccioli LH, Stavropoulos E, Colston MJ, Hewinson RG, Moelling K, Silva CL.

Nature. 1999 Jul 15;400(6741):269-71.

PMID:
10421369
49.

DNA vaccines against tuberculosis.

Lowrie DB, Silva CL, Tascon RE.

Immunol Cell Biol. 1997 Dec;75(6):591-4. Review.

PMID:
9492198
50.

DNA vaccination exploits normal biology.

Lowrie DB.

Nat Med. 1998 Feb;4(2):147-8. No abstract available.

PMID:
9461180

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