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Items: 15


Mannan Molecular Substructures Control Nanoscale Glucan Exposure in Candida.

Graus MS, Wester MJ, Lowman DW, Williams DL, Kruppa MD, Martinez CM, Young JM, Pappas HC, Lidke KA, Neumann AK.

Cell Rep. 2018 Aug 28;24(9):2432-2442.e5. doi: 10.1016/j.celrep.2018.07.088.


Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties.

Smith AJ, Graves B, Child R, Rice PJ, Ma Z, Lowman DW, Ensley HE, Ryter KT, Evans JT, Williams DL.

J Immunol. 2018 Jan 15;200(2):788-799. doi: 10.4049/jimmunol.1701258. Epub 2017 Dec 15.


Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast.

Lowman DW, Greene RR, Bearden DW, Kruppa MD, Pottier M, Monteiro MA, Soldatov DV, Ensley HE, Cheng SC, Netea MG, Williams DL.

J Biol Chem. 2014 Feb 7;289(6):3432-43. doi: 10.1074/jbc.M113.529131. Epub 2013 Dec 16.


Differential virulence of Candida glabrata glycosylation mutants.

West L, Lowman DW, Mora-Montes HM, Grubb S, Murdoch C, Thornhill MH, Gow NA, Williams D, Haynes K.

J Biol Chem. 2013 Jul 26;288(30):22006-18. doi: 10.1074/jbc.M113.478743. Epub 2013 May 28.


The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicans.

Hall RA, Bates S, Lenardon MD, Maccallum DM, Wagener J, Lowman DW, Kruppa MD, Williams DL, Odds FC, Brown AJ, Gow NA.

PLoS Pathog. 2013;9(4):e1003276. doi: 10.1371/journal.ppat.1003276. Epub 2013 Apr 25.


New insights into the structure of (1→3,1→6)-β-D-glucan side chains in the Candida glabrata cell wall.

Lowman DW, West LJ, Bearden DW, Wempe MF, Power TD, Ensley HE, Haynes K, Williams DL, Kruppa MD.

PLoS One. 2011;6(11):e27614. doi: 10.1371/journal.pone.0027614. Epub 2011 Nov 11.


Mannan structural complexity is decreased when Candida albicans is cultivated in blood or serum at physiological temperature.

Lowman DW, Ensley HE, Greene RR, Knagge KJ, Williams DL, Kruppa MD.

Carbohydr Res. 2011 Dec 13;346(17):2752-9. doi: 10.1016/j.carres.2011.09.029. Epub 2011 Oct 2.


C. albicans increases cell wall mannoprotein, but not mannan, in response to blood, serum and cultivation at physiological temperature.

Kruppa M, Greene RR, Noss I, Lowman DW, Williams DL.

Glycobiology. 2011 Sep;21(9):1173-80. doi: 10.1093/glycob/cwr051. Epub 2011 Apr 21.


Identification of (1-->6)-beta-D-glucan as the major carbohydrate component of the Malassezia sympodialis cell wall.

Kruppa MD, Lowman DW, Chen YH, Selander C, Scheynius A, Monteiro MA, Williams DL.

Carbohydr Res. 2009 Dec 14;344(18):2474-9. doi: 10.1016/j.carres.2009.09.029. Epub 2009 Oct 1.


Dendritic cell interaction with Candida albicans critically depends on N-linked mannan.

Cambi A, Netea MG, Mora-Montes HM, Gow NA, Hato SV, Lowman DW, Kullberg BJ, Torensma R, Williams DL, Figdor CG.

J Biol Chem. 2008 Jul 18;283(29):20590-9. doi: 10.1074/jbc.M709334200. Epub 2008 May 15.


Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching.

Adams EL, Rice PJ, Graves B, Ensley HE, Yu H, Brown GD, Gordon S, Monteiro MA, Papp-Szabo E, Lowman DW, Power TD, Wempe MF, Williams DL.

J Pharmacol Exp Ther. 2008 Apr;325(1):115-23. doi: 10.1124/jpet.107.133124. Epub 2008 Jan 2.


Characterization of 'Schizokinen'; a dihydroxamate-type siderophore produced by Rhizobium leguminosarum IARI 917.

Storey EP, Boghozian R, Little JL, Lowman DW, Chakraborty R.

Biometals. 2006 Dec;19(6):637-49. Epub 2006 Jun 7.


Structural characterization of (1-->3)-beta-D-glucans isolated from blastospore and hyphal forms of Candida albicans.

Lowman DW, Ferguson DA, Williams DL.

Carbohydr Res. 2003 Jul 4;338(14):1491-6.


Synthesis and characterization of water-soluble hydroxybutenyl cyclomaltooligosaccharides (cyclodextrins).

Buchanan CM, Alderson SR, Cleven CD, Dixon DW, Ivanyi R, Lambert JL, Lowman DW, Offerman RJ, Szejtli J, Szente L.

Carbohydr Res. 2002 Mar 15;337(6):493-507.


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