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Items: 1 to 50 of 87

1.

A Call to Accelerate Hidradenitis Suppurativa Research and Improve Care-Moving Beyond Burden.

Naik HB, Lowes MA.

JAMA Dermatol. 2019 Jul 10. doi: 10.1001/jamadermatol.2019.1105. [Epub ahead of print] No abstract available.

PMID:
31290934
2.

Hidradenitis Suppurativa Area and Severity Index (HASI): a pilot study to develop a novel instrument to measure the physical signs of hidradenitis suppurativa.

Goldfarb N, Ingram JR, Jemec GBE, Naik HB, Piguet V, Hyde MJ, Freese R, Lowes MA, Alavi A.

Br J Dermatol. 2019 Jul 8. doi: 10.1111/bjd.18335. [Epub ahead of print]

PMID:
31286486
3.

Evaluating Patients' Unmet Needs in Hidradenitis Suppurativa: results from the Global VOICE project.

Garg A, Neuren E, Cha D, Kirby JS, Ingram JR, Jemec GBE, Esmann S, Thorlacius L, Villumsen B, Marmol VD, Nassif A, Delage M, Tzellos T, Moseng D, Grimstad Ø, Naik H, Micheletti R, Guilbault S, Miller AP, Hamzavi I, van der Zee H, Prens E, Kappe N, Ardon C, Kirby B, Hughes R, Zouboulis C, Nikolakis G, Bechara FG, Matusiak L, Szepietowski J, Glowaczewska A, Smith SD, Goldfarb N, Daveluy S, Avgoustou C, Giamarellos-Bourboulis E, Cohen S, Soliman Y, Brant EG, Akilov O, Sayed C, Tan J, Alavi A, Lowes MA, Pascual JC, Riad H, Fisher S, Cohen A, Paek SY, Resnik B, Ju Q, Wang L, Strunk A.

J Am Acad Dermatol. 2019 Jul 3. pii: S0190-9622(19)32300-X. doi: 10.1016/j.jaad.2019.06.1301. [Epub ahead of print]

PMID:
31279015
4.

Defining Lesional, Perilesional and Unaffected Skin in Hidradenitis Suppurativa: Proposed Recommendations for Clinical Trials and Translational Research Studies.

Frew JW, Navrazhina K, Byrd AS, Garg A, Ingram JR, Kirby JS, Lowes MA, Naik H, Piguet V, Prens EP.

Br J Dermatol. 2019 Jul 3. doi: 10.1111/bjd.18309. [Epub ahead of print]

PMID:
31269228
5.

Hemoglobin Levels and Serum C-Reactive Protein in Patients With Moderate to Severe Hidradenitis Suppurativa.

Huang CM, Lowes MA, Cserti C, Alavi A.

J Cutan Med Surg. 2019 Jun 28:1203475419858963. doi: 10.1177/1203475419858963. [Epub ahead of print]

PMID:
31253065
6.

Distribution of Self-reported Hidradenitis Suppurativa Age at Onset.

Naik HB, Paul M, Cohen SR, Alavi A, Suàrez-Fariñas M, Lowes MA.

JAMA Dermatol. 2019 Jun 5. doi: 10.1001/jamadermatol.2019.0478. [Epub ahead of print] No abstract available.

PMID:
31166574
7.

Exploring Changes in Placebo Treatment Arms in Hidradenitis Suppurativa Randomized Clinical Trials: A Systematic Review.

Ali AA, Seng EK, Alavi A, Lowes MA.

J Am Acad Dermatol. 2019 May 28. pii: S0190-9622(19)30869-2. doi: 10.1016/j.jaad.2019.05.065. [Epub ahead of print]

PMID:
31150716
8.

African American Patients With Hidradenitis Suppurativa Have Significant Health Care Disparities: A Retrospective Study.

Soliman YS, Hoffman LK, Guzman AK, Patel ZS, Lowes MA, Cohen SR.

J Cutan Med Surg. 2019 May/Jun;23(3):334-336. doi: 10.1177/1203475418803077. No abstract available.

PMID:
31070094
9.

Proceeding report of the third symposium on Hidradenitis Suppurativa advances (SHSA) 2018.

Posso-De Los Rios CJ, Sarfo A, Ghias M, Alhusayen R, Hamzavi I, Lowes MA, Alavi A.

Exp Dermatol. 2019 Jul;28(7):769-775. doi: 10.1111/exd.13928. Epub 2019 Apr 29.

PMID:
30924968
10.

North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management.

Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y.

J Am Acad Dermatol. 2019 Jul;81(1):76-90. doi: 10.1016/j.jaad.2019.02.067. Epub 2019 Mar 11.

PMID:
30872156
11.

North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management.

Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y.

J Am Acad Dermatol. 2019 Jul;81(1):91-101. doi: 10.1016/j.jaad.2019.02.068. Epub 2019 Mar 11.

PMID:
30872149
12.

Proceeding report of the Second Symposium on Hidradenitis Suppurativa Advances (SHSA) 2017.

Shavit E, Alavi A, Bechara FG, Bennett RG, Bourcier M, Cibotti R, Daveluy S, Frew JW, Garg A, Hamzavi I, Hoffman LK, Hsaio J, Kirby JS, Lev-Tov H, Martinez E, Micheletti R, Naik HB, Nassif A, Nicholson C, Parks-Miller A, Patel Z, Piguet V, Ramesh M, Resnik B, Sayed C, Schultz G, Siddiqui A, Tan J, Wortsman X, Lowes MA.

Exp Dermatol. 2019 Jan;28(1):94-103. doi: 10.1111/exd.13849.

13.

Are Bacteria Infectious Pathogens in Hidradenitis Suppurativa? Debate at the Symposium for Hidradenitis Suppurativa Advances Meeting, November 2017.

Naik HB, Nassif A, Ramesh MS, Schultz G, Piguet V, Alavi A, Lowes MA.

J Invest Dermatol. 2019 Jan;139(1):13-16. doi: 10.1016/j.jid.2018.09.036. Epub 2018 Nov 8.

PMID:
30414909
14.

Integrating the skin and blood transcriptomes and serum proteome in hidradenitis suppurativa reveals complement dysregulation and a plasma cell signature.

Hoffman LK, Tomalin LE, Schultz G, Howell MD, Anandasabapathy N, Alavi A, Suárez-Fariñas M, Lowes MA.

PLoS One. 2018 Sep 28;13(9):e0203672. doi: 10.1371/journal.pone.0203672. eCollection 2018.

15.

A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.

Shipman WD, Chyou S, Ramanathan A, Izmirly PM, Sharma S, Pannellini T, Dasoveanu DC, Qing X, Magro CM, Granstein RD, Lowes MA, Pamer EG, Kaplan DH, Salmon JE, Mehrara BJ, Young JW, Clancy RM, Blobel CP, Lu TT.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaap9527. doi: 10.1126/scitranslmed.aap9527.

16.

Hemoglobin as an indicator of disease activity in severe hidradenitis suppurativa.

Braunberger TL, Lowes MA, Hamzavi IH.

Int J Dermatol. 2018 Aug 10. doi: 10.1111/ijd.14170. [Epub ahead of print] No abstract available.

PMID:
30094834
17.

Quality of life and sexual health in patients with hidradenitis suppurativa.

Alavi A, Farzanfar D, Rogalska T, Lowes MA, Chavoshi S.

Int J Womens Dermatol. 2018 Feb 1;4(2):74-79. doi: 10.1016/j.ijwd.2017.10.007. eCollection 2018 Jun.

18.

Inflammation: A Contributor to Depressive Comorbidity in Inflammatory Skin Disease.

Farzanfar D, Dowlati Y, French LE, Lowes MA, Alavi A.

Skin Pharmacol Physiol. 2018;31(5):246-251. doi: 10.1159/000490002. Epub 2018 Jun 28. Review.

19.

Correction to: Pain, Psychological Comorbidities, Disability, and Impaired Quality of Life in Hidradenitis Suppurativa.

Patel ZS, Hoffman LK, Buse DC, Grinberg AS, Afifi L, Cohen SR, Lowes MA, Seng EK.

Curr Pain Headache Rep. 2017 Nov 18;21(12):52. doi: 10.1007/s11916-017-0653-5.

PMID:
29151223
20.

Pain, Psychological Comorbidities, Disability, and Impaired Quality of Life in Hidradenitis Suppurativa [corrected].

Patel ZS, Hoffman LK, Buse DC, Grinberg AS, Afifi L, Cohen SR, Lowes MA, Seng EK.

Curr Pain Headache Rep. 2017 Nov 1;21(12):49. doi: 10.1007/s11916-017-0647-3. Review. Erratum in: Curr Pain Headache Rep. 2017 Nov 18;21(12 ):52.

21.

Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment.

Kim J, Tomalin L, Lee J, Fitz LJ, Berstein G, Correa-da Rosa J, Garcet S, Lowes MA, Valdez H, Wolk R, Suarez-Farinas M, Krueger JG.

J Invest Dermatol. 2018 Feb;138(2):273-281. doi: 10.1016/j.jid.2017.08.040. Epub 2017 Sep 18.

22.

Proceeding report of the Symposium on Hidradenitis Suppurativa Advances (SHSA).

Mehdizadeh A, Alavi A, Alhusayen R, Bauer B, Bechara FG, Bourcier M, Brassard A, Djamei V, Dutz J, George R, Ghias M, Gooderham M, Hamzavi I, Hoffman LK, Hou A, Hu H, Kimball AB, Kirchhof M, Kryzskaya D, Liy Wong MDC, Lowes MA, Lynde CW, McLellen C, Prens E, Prens L, Rogalska T, Sibbald RG, Sisic M, Tan MG, Wong DD.

Exp Dermatol. 2018 Jan;27(1):104-112. doi: 10.1111/exd.13445. Epub 2017 Nov 15.

PMID:
28898476
23.

Polyclonal hyperglobulinaemia and elevated acute-phase reactants in hidradenitis suppurativa.

Hoffman LK, Ghias MH, Cohen SR, Lowes MA.

Br J Dermatol. 2018 Feb;178(2):e134-e135. doi: 10.1111/bjd.15958. Epub 2018 Jan 8. No abstract available.

PMID:
28886222
24.

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.

Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, Song-Zhao GX, Gulati N, Lowes MA, King SL, Quintana FJ, Lee YS, Krueger JG, Sarin KY, Yoon CH, Garraway L, Regev A, Shalek AK, Troyanskaya O, Anandasabapathy N.

Cell. 2017 Jun 29;170(1):127-141.e15. doi: 10.1016/j.cell.2017.06.016.

25.

Major gaps in understanding and treatment of hidradenitis suppurativa.

Hoffman LK, Ghias MH, Garg A, Hamzavi IH, Alavi A, Lowes MA.

Semin Cutan Med Surg. 2017 Jun;36(2):86-92. doi: 10.12788/j.sder.2017.024.

PMID:
28538750
26.

Pathophysiology of hidradenitis suppurativa.

Hoffman LK, Ghias MH, Lowes MA.

Semin Cutan Med Surg. 2017 Jun;36(2):47-54. doi: 10.12788/j.sder.2017.017.

PMID:
28538743
27.

A randomized clinical trial in vitamin D-deficient adults comparing replenishment with oral vitamin D3 with narrow-band UV type B light: effects on cholesterol and the transcriptional profiles of skin and blood.

Ponda MP, Liang Y, Kim J, Hutt R, Dowd K, Gilleaudeau P, Sullivan-Whalen MM, Rodrick T, Kim DJ, Barash I, Lowes MA, Breslow JL.

Am J Clin Nutr. 2017 May;105(5):1230-1238. doi: 10.3945/ajcn.116.150367. Epub 2017 Feb 22.

28.

Isotretinoin treatment in a patient with known peanut allergy and positive IgE test results for soybean.

Alvarez-Arango S, Hou A, Lowes MA, Jerschow E.

Ann Allergy Asthma Immunol. 2016 Nov;117(5):558-559. doi: 10.1016/j.anai.2016.08.019. Epub 2016 Sep 23. No abstract available.

PMID:
27670093
29.

The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes.

Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG.

J Invest Dermatol. 2016 Nov;136(11):2173-2182. doi: 10.1016/j.jid.2016.04.032. Epub 2016 May 13.

30.

Patients With Psoriasis and Personalized Trade-offs in Treatment Decisions-Lessons Learned From Focus Groups.

Kim J, Kim DJ, Ortenzio FS, Dare L, Frank C, Kost RG, Lowes MA.

JAMA Dermatol. 2016 Jun 1;152(6):720-2. doi: 10.1001/jamadermatol.2016.0501. No abstract available.

31.

Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets.

Kim J, Oh CH, Jeon J, Baek Y, Ahn J, Kim DJ, Lee HS, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG.

J Invest Dermatol. 2016 Jan;136(1):161-172. doi: 10.1038/JID.2015.378.

32.

The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases.

Harden JL, Lewis SM, Lish SR, Suárez-Fariñas M, Gareau D, Lentini T, Johnson-Huang LM, Krueger JG, Lowes MA.

J Allergy Clin Immunol. 2016 Jun;137(6):1830-1840. doi: 10.1016/j.jaci.2015.09.055. Epub 2015 Dec 22.

33.

Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis.

Harden JL, Hamm D, Gulati N, Lowes MA, Krueger JG.

F1000Res. 2015 Aug 3;4:460. doi: 10.12688/f1000research.6756.1. eCollection 2015.

34.

CARD14 expression in dermal endothelial cells in psoriasis.

Harden JL, Lewis SM, Pierson KC, Suárez-Fariñas M, Lentini T, Ortenzio FS, Zaba LC, Goldbach-Mansky R, Bowcock AM, Lowes MA.

PLoS One. 2014 Nov 4;9(11):e111255. doi: 10.1371/journal.pone.0111255. eCollection 2014.

35.

Humanized anti-IFN-γ (HuZAF) in the treatment of psoriasis.

Harden JL, Johnson-Huang LM, Chamian MF, Lee E, Pearce T, Leonardi CL, Haider A, Lowes MA, Krueger JG.

J Allergy Clin Immunol. 2015 Feb;135(2):553-6. doi: 10.1016/j.jaci.2014.05.046. Epub 2014 Jul 29. No abstract available.

PMID:
25085340
36.

Immunology of psoriasis.

Lowes MA, Suárez-Fariñas M, Krueger JG.

Annu Rev Immunol. 2014;32:227-55. doi: 10.1146/annurev-immunol-032713-120225. Review.

37.

IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis.

Wang CQF, Akalu YT, Suarez-Farinas M, Gonzalez J, Mitsui H, Lowes MA, Orlow SJ, Manga P, Krueger JG.

J Invest Dermatol. 2013 Dec;133(12):2741-2752. doi: 10.1038/jid.2013.237. Epub 2013 Apr 30.

38.

TREM-1 as a potential therapeutic target in psoriasis.

Hyder LA, Gonzalez J, Harden JL, Johnson-Huang LM, Zaba LC, Pierson KC, Eungdamrong NJ, Lentini T, Gulati N, Fuentes-Duculan J, Suárez-Fariñas M, Lowes MA.

J Invest Dermatol. 2013 Jul;133(7):1742-51. doi: 10.1038/jid.2013.68. Epub 2013 Feb 13.

39.

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.

Lowes MA, Russell CB, Martin DA, Towne JE, Krueger JG.

Trends Immunol. 2013 Apr;34(4):174-81. doi: 10.1016/j.it.2012.11.005. Epub 2013 Jan 3. Review.

40.

Homeostatic tissue responses in skin biopsies from NOMID patients with constitutive overproduction of IL-1β.

Aubert P, Suárez-Fariñas M, Mitsui H, Johnson-Huang LM, Harden JL, Pierson KC, Dolan JG, Novitskaya I, Coats I, Estes J, Cowen EW, Plass N, Lee CC, Sun HW, Lowes MA, Goldbach-Mansky R.

PLoS One. 2012;7(11):e49408. doi: 10.1371/journal.pone.0049408. Epub 2012 Nov 30.

41.

Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses.

Kennedy Crispin M, Fuentes-Duculan J, Gulati N, Johnson-Huang LM, Lentini T, Sullivan-Whalen M, Gilleaudeau P, Cueto I, Suárez-Fariñas M, Lowes MA, Krueger JG.

J Invest Dermatol. 2013 Mar;133(3):692-701. doi: 10.1038/jid.2012.359. Epub 2012 Nov 15.

42.

Meta-analysis derived (MAD) transcriptome of psoriasis defines the "core" pathogenesis of disease.

Tian S, Krueger JG, Li K, Jabbari A, Brodmerkel C, Lowes MA, Suárez-Fariñas M.

PLoS One. 2012;7(9):e44274. doi: 10.1371/journal.pone.0044274. Epub 2012 Sep 5.

43.

Putting together the psoriasis puzzle: an update on developing targeted therapies.

Johnson-Huang LM, Lowes MA, Krueger JG.

Dis Model Mech. 2012 Jul;5(4):423-33. doi: 10.1242/dmm.009092. Review.

44.

Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

Jordan CT, Cao L, Roberson ED, Duan S, Helms CA, Nair RP, Duffin KC, Stuart PE, Goldgar D, Hayashi G, Olfson EH, Feng BJ, Pullinger CR, Kane JP, Wise CA, Goldbach-Mansky R, Lowes MA, Peddle L, Chandran V, Liao W, Rahman P, Krueger GG, Gladman D, Elder JT, Menter A, Bowcock AM.

Am J Hum Genet. 2012 May 4;90(5):796-808. doi: 10.1016/j.ajhg.2012.03.013. Epub 2012 Apr 19.

45.

PSORS2 is due to mutations in CARD14.

Jordan CT, Cao L, Roberson ED, Pierson KC, Yang CF, Joyce CE, Ryan C, Duan S, Helms CA, Liu Y, Chen Y, McBride AA, Hwu WL, Wu JY, Chen YT, Menter A, Goldbach-Mansky R, Lowes MA, Bowcock AM.

Am J Hum Genet. 2012 May 4;90(5):784-95. doi: 10.1016/j.ajhg.2012.03.012. Epub 2012 Apr 19.

46.

Post-therapeutic relapse of psoriasis after CD11a blockade is associated with T cells and inflammatory myeloid DCs.

Johnson-Huang LM, Pensabene CA, Shah KR, Pierson KC, Kikuchi T, Lentini T, Gilleaudeau P, Sullivan-Whalen M, Cueto I, Khatcherian A, Hyder LA, Suárez-Fariñas M, Krueger JG, Lowes MA.

PLoS One. 2012;7(2):e30308. doi: 10.1371/journal.pone.0030308. Epub 2012 Feb 10.

47.

A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin.

Johnson-Huang LM, Suárez-Fariñas M, Pierson KC, Fuentes-Duculan J, Cueto I, Lentini T, Sullivan-Whalen M, Gilleaudeau P, Krueger JG, Haider AS, Lowes MA.

J Invest Dermatol. 2012 Apr;132(4):1177-87. doi: 10.1038/jid.2011.458. Epub 2012 Jan 26.

48.

Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated.

Pettersen JS, Fuentes-Duculan J, Suárez-Fariñas M, Pierson KC, Pitts-Kiefer A, Fan L, Belkin DA, Wang CQ, Bhuvanendran S, Johnson-Huang LM, Bluth MJ, Krueger JG, Lowes MA, Carucci JA.

J Invest Dermatol. 2011 Jun;131(6):1322-30. doi: 10.103/jid.2011.9. Epub 2011 Feb 10.

49.

Resolved psoriasis lesions retain expression of a subset of disease-related genes.

Suárez-Fariñas M, Fuentes-Duculan J, Lowes MA, Krueger JG.

J Invest Dermatol. 2011 Feb;131(2):391-400. doi: 10.1038/jid.2010.280. Epub 2010 Sep 23.

50.

A subpopulation of CD163-positive macrophages is classically activated in psoriasis.

Fuentes-Duculan J, Suárez-Fariñas M, Zaba LC, Nograles KE, Pierson KC, Mitsui H, Pensabene CA, Kzhyshkowska J, Krueger JG, Lowes MA.

J Invest Dermatol. 2010 Oct;130(10):2412-22. doi: 10.1038/jid.2010.165. Epub 2010 Jun 17.

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