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Items: 32


Multiscale modeling of glioblastoma.

Yan H, Romero-López M, Benitez LI, Di K, Frieboes HB, Hughes CCW, Bota DA, Lowengrub JS.

Transl Cancer Res. 2018 Feb;7(Suppl 1):S96-S98. doi: 10.21037/tcr.2017.12.10. No abstract available.


A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma.

Koay EJ, Lee Y, Cristini V, Lowengrub JS, Kang Y, Lucas FAS, Hobbs BP, Ye R, Elganainy D, Almahariq M, Amer AM, Chatterjee D, Yan H, Park PC, Rios Perez MV, Li D, Garg N, Reiss KA, Yu S, Chauhan A, Zaid M, Nikzad N, Wolff RA, Javle M, Varadhachary GR, Shroff RT, Das P, Lee JE, Ferrari M, Maitra A, Taniguchi CM, Kim MP, Crane CH, Katz MH, Wang H, Bhosale P, Tamm EP, Fleming JB.

Clin Cancer Res. 2018 Aug 6. doi: 10.1158/1078-0432.CCR-17-3668. [Epub ahead of print]


Modeling solvent evaporation during thin film formation in phase separating polymer mixtures.

Cummings J, Lowengrub JS, Sumpter BG, Wise SM, Kumar R.

Soft Matter. 2018 Mar 7;14(10):1833-1846. doi: 10.1039/c7sm02560b.


Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model.

Konstorum A, Lowengrub JS.

J Theor Biol. 2018 Feb 14;439:86-99. doi: 10.1016/j.jtbi.2017.11.025. Epub 2017 Dec 5.


3D Mathematical Modeling of Glioblastoma Suggests That Transdifferentiated Vascular Endothelial Cells Mediate Resistance to Current Standard-of-Care Therapy.

Yan H, Romero-López M, Benitez LI, Di K, Frieboes HB, Hughes CCW, Bota DA, Lowengrub JS.

Cancer Res. 2017 Aug 1;77(15):4171-4184. doi: 10.1158/0008-5472.CAN-16-3094. Epub 2017 May 23.


Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth.

Romero-López M, Trinh AL, Sobrino A, Hatch MM, Keating MT, Fimbres C, Lewis DE, Gershon PD, Botvinick EL, Digman M, Lowengrub JS, Hughes CC.

Biomaterials. 2017 Feb;116:118-129. doi: 10.1016/j.biomaterials.2016.11.034. Epub 2016 Nov 24.


Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression Without Increasing Invasiveness.

Yan H, Romero-Lopez M, Frieboes HB, Hughes CC, Lowengrub JS.

IEEE Trans Biomed Eng. 2017 Mar;64(3):538-548. doi: 10.1109/TBME.2016.2615566. Epub 2016 Oct 7.


Feedback, Lineages and Self-Organizing Morphogenesis.

Kunche S, Yan H, Calof AL, Lowengrub JS, Lander AD.

PLoS Comput Biol. 2016 Mar 18;12(3):e1004814. doi: 10.1371/journal.pcbi.1004814. eCollection 2016 Mar.


Collective Properties of a Transcription Initiation Model Under Varying Environment.

Hu Y, Lowengrub JS.

J Comput Biol. 2016 Jan;23(1):56-66. doi: 10.1089/cmb.2015.0144. Epub 2015 Dec 8.


Predicting mechanism of biphasic growth factor action on tumor growth using a multi-species model with feedback control.

Konstorum A, Sprowl SA, Waterman ML, Lander AD, Lowengrub JS.

J Coupled Syst Multiscale Dyn. 2013 Dec 1;1(4):459-467.


Tumor growth in complex, evolving microenvironmental geometries: a diffuse domain approach.

Chen Y, Lowengrub JS.

J Theor Biol. 2014 Nov 21;361:14-30. doi: 10.1016/j.jtbi.2014.06.024. Epub 2014 Jul 9.


The effect of interstitial pressure on therapeutic agent transport: coupling with the tumor blood and lymphatic vascular systems.

Wu M, Frieboes HB, Chaplain MA, McDougall SR, Cristini V, Lowengrub JS.

J Theor Biol. 2014 Aug 21;355:194-207. doi: 10.1016/j.jtbi.2014.04.012. Epub 2014 Apr 19.


A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane.

Chen Y, Wise SM, Shenoy VB, Lowengrub JS.

Int J Numer Method Biomed Eng. 2014 Jul;30(7):726-54. doi: 10.1002/cnm.2624. Epub 2014 Jan 17.


Multispecies model of cell lineages and feedback control in solid tumors.

Youssefpour H, Li X, Lander AD, Lowengrub JS.

J Theor Biol. 2012 Jul 7;304:39-59. doi: 10.1016/j.jtbi.2012.02.030. Epub 2012 Mar 31.


Dynamic density functional theory of solid tumor growth: Preliminary models.

Chauviere A, Hatzikirou H, Kevrekidis IG, Lowengrub JS, Cristini V.

AIP Adv. 2012 Mar;2(1):11210. Epub 2012 Mar 22.


Axisymmetric multicomponent vesicles: A comparison of hydrodynamic and geometric models.

Sohn J, Li S, Li X, Lowengrub JS.

Int J Numer Method Biomed Eng. 2012 Mar;28(3):346-68.


Physical oncology: a bench-to-bedside quantitative and predictive approach.

Frieboes HB, Chaplain MA, Thompson AM, Bearer EL, Lowengrub JS, Cristini V.

Cancer Res. 2011 Jan 15;71(2):298-302. doi: 10.1158/0008-5472.CAN-10-2676. Epub 2011 Jan 11. Review. Erratum in: Cancer Res. 2011 Mar 1;71(5):2024.


Mathematical Oncology: How Are the Mathematical and Physical Sciences Contributing to the War on Breast Cancer?

Chauviere AH, Hatzikirou H, Lowengrub JS, Frieboes HB, Thompson AM, Cristini V.

Curr Breast Cancer Rep. 2010 Sep;2(3):121-129. Epub 2010 Jul 22.


An Adaptive Multigrid Algorithm for Simulating Solid Tumor Growth Using Mixture Models.

Wise SM, Lowengrub JS, Cristini V.

Math Comput Model. 2011 Jan 1;53(1-2):1-20.


Nonlinear modelling of cancer: bridging the gap between cells and tumours.

Lowengrub JS, Frieboes HB, Jin F, Chuang YL, Li X, Macklin P, Wise SM, Cristini V.

Nonlinearity. 2010;23(1):R1-R9.


Dynamics of multicomponent vesicles in a viscous fluid.

Sohn JS, Tseng YH, Li S, Voigt A, Lowengrub JS.

J Comput Phys. 2010;229(1):119-144.


Selection in spatial stochastic models of cancer: migration as a key modulator of fitness.

Thalhauser CJ, Lowengrub JS, Stupack D, Komarova NL.

Biol Direct. 2010 Apr 20;5:21. doi: 10.1186/1745-6150-5-21.


Three-dimensional multispecies nonlinear tumor growth-II: Tumor invasion and angiogenesis.

Frieboes HB, Jin F, Chuang YL, Wise SM, Lowengrub JS, Cristini V.

J Theor Biol. 2010 Jun 21;264(4):1254-78. doi: 10.1016/j.jtbi.2010.02.036. Epub 2010 Mar 18.


Control of viscous fingering patterns in a radial Hele-Shaw cell.

Li S, Lowengrub JS, Fontana J, Palffy-Muhoray P.

Phys Rev Lett. 2009 May 1;102(17):174501. Epub 2009 Apr 30.


Phase-field modeling of the dynamics of multicomponent vesicles: Spinodal decomposition, coarsening, budding, and fission.

Lowengrub JS, Rätz A, Voigt A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Mar;79(3 Pt 1):031926. Epub 2009 Mar 31.


Multiparameter computational modeling of tumor invasion.

Bearer EL, Lowengrub JS, Frieboes HB, Chuang YL, Jin F, Wise SM, Ferrari M, Agus DB, Cristini V.

Cancer Res. 2009 May 15;69(10):4493-501. doi: 10.1158/0008-5472.CAN-08-3834. Epub 2009 Apr 14.


Nonlinear simulations of solid tumor growth using a mixture model: invasion and branching.

Cristini V, Li X, Lowengrub JS, Wise SM.

J Math Biol. 2009 Apr;58(4-5):723-63. doi: 10.1007/s00285-008-0215-x. Epub 2008 Sep 12.


Three-dimensional multispecies nonlinear tumor growth--I Model and numerical method.

Wise SM, Lowengrub JS, Frieboes HB, Cristini V.

J Theor Biol. 2008 Aug 7;253(3):524-43. doi: 10.1016/j.jtbi.2008.03.027. Epub 2008 Mar 28.


Linear stability analysis for step meandering instabilities with elastic interactions and Ehrlich-Schwoebel barriers.

Yeon DH, Cha PR, Lowengrub JS, Voigt A, Thornton K.

Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jul;76(1 Pt 1):011601. Epub 2007 Jul 11.


Computer simulation of glioma growth and morphology.

Frieboes HB, Lowengrub JS, Wise S, Zheng X, Macklin P, Bearer EL, Cristini V.

Neuroimage. 2007;37 Suppl 1:S59-70. Epub 2007 Mar 23.

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