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Design strategies for programmable oligonucleotide nanotherapeutics.

Sahle FF, Lowe TL.

Drug Discov Today. 2019 Sep 13. pii: S1359-6446(19)30350-2. doi: 10.1016/j.drudis.2019.09.006. [Epub ahead of print] Review.


Distinct modified nucleosides in tRNATrp from the hyperthermophilic archaeon Thermococcus kodakarensis and requirement of tRNA m2G10/m2 2G10 methyltransferase (archaeal Trm11) for survival at high temperatures.

Hirata A, Suzuki T, Nagano T, Fujii D, Okamoto M, Sora M, Lowe TM, Kanai T, Atomi H, Suzuki T, Hori H.

J Bacteriol. 2019 Aug 12. pii: JB.00448-19. doi: 10.1128/JB.00448-19. [Epub ahead of print]


Superficial parotidectomy versus extracapsular dissection: literature review and search for a gold standard technique.

Martin H, Jayasinghe J, Lowe T.

Int J Oral Maxillofac Surg. 2019 Jul 11. pii: S0901-5027(19)31180-4. doi: 10.1016/j.ijom.2019.06.006. [Epub ahead of print] Review.


Traditional cauterisation in an infant.

Lowe T, Jilani N, Al Ansari K, Powell C.

Arch Dis Child. 2019 Jun 13. pii: archdischild-2019-317266. doi: 10.1136/archdischild-2019-317266. [Epub ahead of print] No abstract available.


tRNAviz: explore and visualize tRNA sequence features.

Lin BY, Chan PP, Lowe TM.

Nucleic Acids Res. 2019 Jul 2;47(W1):W542-W547. doi: 10.1093/nar/gkz438.


tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences.

Chan PP, Lowe TM.

Methods Mol Biol. 2019;1962:1-14. doi: 10.1007/978-1-4939-9173-0_1.


One- and two-stage anaerobic co-digestion of cucumber waste and sewage sludge.

Lowe TB, Hatch BT, Antle C, Nartker S, Ammerman ML.

Environ Technol. 2019 Mar 28:1-9. doi: 10.1080/09593330.2019.1601262. [Epub ahead of print]


HOPON (Hyperbaric Oxygen for the Prevention of Osteoradionecrosis): A Randomized Controlled Trial of Hyperbaric Oxygen to Prevent Osteoradionecrosis of the Irradiated Mandible After Dentoalveolar Surgery.

Shaw RJ, Butterworth CJ, Silcocks P, Tesfaye BT, Bickerstaff M, Jackson R, Kanatas A, Nixon P, McCaul J, Praveen P, Lowe T, Blanco-Guzman M, Forner L, Brennan P, Fardy M, Parkin R, Smerdon G, Stephenson R, Cope T, Glover M.

Int J Radiat Oncol Biol Phys. 2019 Jul 1;104(3):530-539. doi: 10.1016/j.ijrobp.2019.02.044. Epub 2019 Mar 7.


Long-Term Follow-up of Patients with Tourette's Syndrome.

Lowe TL, Capriotti MR, McBurnett K.

Mov Disord Clin Pract. 2018 Nov 16;6(1):40-45. doi: 10.1002/mdc3.12696. eCollection 2019 Jan.


Matching tRNA modifications in humans to their known and predicted enzymes.

de Crécy-Lagard V, Boccaletto P, Mangleburg CG, Sharma P, Lowe TM, Leidel SA, Bujnicki JM.

Nucleic Acids Res. 2019 Mar 18;47(5):2143-2159. doi: 10.1093/nar/gkz011.


3D Imaging of Indentation Damage in Bone.

Lowe T, Avcu E, Bousser E, Sellers W, Withers PJ.

Materials (Basel). 2018 Dec 13;11(12). pii: E2533. doi: 10.3390/ma11122533.


Four-Dimensional Imaging of Soft Tissue and Implanted Biomaterial Mechanics: A Barbed Suture Case Study for Tendon Repair.

Rawson SD, Shearer T, Lowe T, O'Brien M, Wong JKF, Margetts L, Cartmell SH.

ACS Appl Mater Interfaces. 2018 Nov 14;10(45):38681-38691. doi: 10.1021/acsami.8b09700. Epub 2018 Nov 5.


Design strategies for chemical-stimuli-responsive programmable nanotherapeutics.

Gulfam M, Sahle FF, Lowe TL.

Drug Discov Today. 2019 Jan;24(1):129-147. doi: 10.1016/j.drudis.2018.09.019. Epub 2018 Oct 5.


Morphological Substrates for Atrial Arrhythmogenesis in a Heart With Atrioventricular Septal Defect.

Stephenson RS, Rowley-Nobel J, Jones CB, Guerrero R, Lowe T, Zhao J, Zhang H, Jarvis JC.

Front Physiol. 2018 Aug 23;9:1071. doi: 10.3389/fphys.2018.01071. eCollection 2018.


Transfer RNA genes experience exceptionally elevated mutation rates.

Thornlow BP, Hough J, Roger JM, Gong H, Lowe TM, Corbett-Detig RB.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):8996-9001. doi: 10.1073/pnas.1801240115. Epub 2018 Aug 20.


Methylation guide RNA evolution in archaea: structure, function and genomic organization of 110 C/D box sRNA families across six Pyrobaculum species.

Lui LM, Uzilov AV, Bernick DL, Corredor A, Lowe TM, Dennis PP.

Nucleic Acids Res. 2018 Jun 20;46(11):5678-5691. doi: 10.1093/nar/gky284.


Design strategies for physical-stimuli-responsive programmable nanotherapeutics.

Sahle FF, Gulfam M, Lowe TL.

Drug Discov Today. 2018 May;23(5):992-1006. doi: 10.1016/j.drudis.2018.04.003. Epub 2018 Apr 10. Review.


Thermoresponsive- co-Biodegradable Linear-Dendritic Nanoparticles for Sustained Release of Nerve Growth Factor To Promote Neurite Outgrowth.

Kim YS, Gulfam M, Lowe TL.

Mol Pharm. 2018 Apr 2;15(4):1467-1475. doi: 10.1021/acs.molpharmaceut.7b01044. Epub 2018 Mar 6.


A kilonova as the electromagnetic counterpart to a gravitational-wave source.

Smartt SJ, Chen TW, Jerkstrand A, Coughlin M, Kankare E, Sim SA, Fraser M, Inserra C, Maguire K, Chambers KC, Huber ME, Krühler T, Leloudas G, Magee M, Shingles LJ, Smith KW, Young DR, Tonry J, Kotak R, Gal-Yam A, Lyman JD, Homan DS, Agliozzo C, Anderson JP, Angus CR, Ashall C, Barbarino C, Bauer FE, Berton M, Botticella MT, Bulla M, Bulger J, Cannizzaro G, Cano Z, Cartier R, Cikota A, Clark P, De Cia A, Della Valle M, Denneau L, Dennefeld M, Dessart L, Dimitriadis G, Elias-Rosa N, Firth RE, Flewelling H, Flörs A, Franckowiak A, Frohmaier C, Galbany L, González-Gaitán S, Greiner J, Gromadzki M, Guelbenzu AN, Gutiérrez CP, Hamanowicz A, Hanlon L, Harmanen J, Heintz KE, Heinze A, Hernandez MS, Hodgkin ST, Hook IM, Izzo L, James PA, Jonker PG, Kerzendorf WE, Klose S, Kostrzewa-Rutkowska Z, Kowalski M, Kromer M, Kuncarayakti H, Lawrence A, Lowe TB, Magnier EA, Manulis I, Martin-Carrillo A, Mattila S, McBrien O, Müller A, Nordin J, O'Neill D, Onori F, Palmerio JT, Pastorello A, Patat F, Pignata G, Podsiadlowski P, Pumo ML, Prentice SJ, Rau A, Razza A, Rest A, Reynolds T, Roy R, Ruiter AJ, Rybicki KA, Salmon L, Schady P, Schultz ASB, Schweyer T, Seitenzahl IR, Smith M, Sollerman J, Stalder B, Stubbs CW, Sullivan M, Szegedi H, Taddia F, Taubenberger S, Terreran G, van Soelen B, Vos J, Wainscoat RJ, Walton NA, Waters C, Weiland H, Willman M, Wiseman P, Wright DE, Wyrzykowski Ł, Yaron O.

Nature. 2017 Nov 2;551(7678):75-79. doi: 10.1038/nature24303. Epub 2017 Oct 16.


Stress response of a marine ammonia-oxidizing archaeon informs physiological status of environmental populations.

Qin W, Amin SA, Lundeen RA, Heal KR, Martens-Habbena W, Turkarslan S, Urakawa H, Costa KC, Hendrickson EL, Wang T, Beck DA, Tiquia-Arashiro SM, Taub F, Holmes AD, Vajrala N, Berube PM, Lowe TM, Moffett JW, Devol AH, Baliga NS, Arp DJ, Sayavedra-Soto LA, Hackett M, Armbrust EV, Ingalls AE, Stahl DA.

ISME J. 2018 Feb;12(2):508-519. doi: 10.1038/ismej.2017.186. Epub 2017 Oct 20.


The Use of Hamstring Fatigue to Reduce Quadriceps Inhibition After Anterior Cruciate Ligament Reconstruction.

Lowe T, Dong XN.

Percept Mot Skills. 2018 Feb;125(1):81-92. doi: 10.1177/0031512517735744. Epub 2017 Oct 11.


Clinical nonlicensed personnel in U.S. hospitals: Job trends from 2010 to 2015.

Pittman P, Li S, Han X, Lowe T.

Nurs Outlook. 2018 Jan - Feb;66(1):35-45. doi: 10.1016/j.outlook.2017.06.014. Epub 2017 Jul 21.


Increased ethanol drinking in "humanized" mice expressing the mu opioid receptor A118G polymorphism are mediated through sex-specific mechanisms.

Henderson-Redmond AN, Lowe TE, Tian XB, Morgan DJ.

Brain Res Bull. 2018 Apr;138:12-19. doi: 10.1016/j.brainresbull.2017.07.017. Epub 2017 Aug 2.


The Effect of Adding Comorbidities to Current Centers for Disease Control and Prevention Central-Line-Associated Bloodstream Infection Risk-Adjustment Methodology.

Jackson SS, Leekha S, Magder LS, Pineles L, Anderson DJ, Trick WE, Woeltje KF, Kaye KS, Stafford K, Thom K, Lowe TJ, Harris AD.

Infect Control Hosp Epidemiol. 2017 Sep;38(9):1019-1024. doi: 10.1017/ice.2017.129. Epub 2017 Jul 3.


A study of the progression of damage in an axially loaded Branta leucopsis femur using X-ray computed tomography and digital image correlation.

Mustansar Z, McDonald SA, Sellers WI, Manning PL, Lowe T, Withers PJ, Margetts L.

PeerJ. 2017 Jun 23;5:e3416. doi: 10.7717/peerj.3416. eCollection 2017.


Electronically Available Comorbidities Should Be Used in Surgical Site Infection Risk Adjustment.

Jackson SS, Leekha S, Magder LS, Pineles L, Anderson DJ, Trick WE, Woeltje KF, Kaye KS, Lowe TJ, Harris AD.

Clin Infect Dis. 2017 Sep 1;65(5):803-810. doi: 10.1093/cid/cix431.


Nanoparticles for drug delivery to the anterior segment of the eye.

Janagam DR, Wu L, Lowe TL.

Adv Drug Deliv Rev. 2017 Dec 1;122:31-64. doi: 10.1016/j.addr.2017.04.001. Epub 2017 Apr 6. Review.


High-Throughput Small RNA Sequencing Enhanced by AlkB-Facilitated RNA de-Methylation (ARM-Seq).

Hrabeta-Robinson E, Marcus E, Cozen AE, Phizicky EM, Lowe TM.

Methods Mol Biol. 2017;1562:231-243. doi: 10.1007/978-1-4939-6807-7_15.


Nurse-Related Clinical Nonlicensed Personnel in U.S. Hospitals and Their Relationship with Nurse Staffing Levels.

Li S, Pittman P, Han X, Lowe TJ.

Health Serv Res. 2017 Feb;52 Suppl 1:422-436. doi: 10.1111/1475-6773.12655.


Combined effect of grain refinement and surface modification of pure titanium on the attachment of mesenchymal stem cells and osteoblast-like SaOS-2 cells.

Medvedev AE, Neumann A, Ng HP, Lapovok R, Kasper C, Lowe TC, Anumalasetty VN, Estrin Y.

Mater Sci Eng C Mater Biol Appl. 2017 Feb 1;71:483-497. doi: 10.1016/j.msec.2016.10.035. Epub 2016 Oct 19.


Examining the Supply of and Demand for Physiotherapy in Saskatchewan: The Relationship between Where Physiotherapists Work and Population Health Need.

McFadden B, Jones McGrath K, Lowe T, Thiessen C, Irinici S, Shah T, Milosavljevic S, Bath B.

Physiother Can. 2016;68(4):335-345.


Efficacy and Safety of Onartuzumab in Combination With First-Line Bevacizumab- or Pemetrexed-Based Chemotherapy Regimens in Advanced Non-Squamous Non-Small-Cell Lung Cancer.

Wakelee H, Zvirbule Z, De Braud F, Kingsley CD, Mekhail T, Lowe T, Schütte W, Lena H, Lawler W, Braiteh F, Cosgriff T, Kaen D, Boyer M, Hsu J, Phan S, Novello S.

Clin Lung Cancer. 2017 Jan;18(1):50-59. doi: 10.1016/j.cllc.2016.09.013. Epub 2016 Oct 19.


Small RNA Modifications: Integral to Function and Disease.

Zhang X, Cozen AE, Liu Y, Chen Q, Lowe TM.

Trends Mol Med. 2016 Dec;22(12):1025-1034. doi: 10.1016/j.molmed.2016.10.009. Epub 2016 Nov 11. Review.


RNAcentral: a comprehensive database of non-coding RNA sequences.

The RNAcentral Consortium, Petrov AI, Kay SJE, Kalvari I, Howe KL, Gray KA, Bruford EA, Kersey PJ, Cochrane G, Finn RD, Bateman A, Kozomara A, Griffiths-Jones S, Frankish A, Zwieb CW, Lau BY, Williams KP, Chan PP, Lowe TM, Cannone JJ, Gutell R, Machnicka MA, Bujnicki JM, Yoshihama M, Kenmochi N, Chai B, Cole JR, Szymanski M, Karlowski WM, Wood V, Huala E, Berardini TZ, Zhao Y, Chen R, Zhu W, Paraskevopoulou MD, Vlachos IS, Hatzigeorgiou AG, Ma L, Zhang Z, Puetz J, Stadler PF, McDonald D, Basu S, Fey P, Engel SR, Cherry JM, Volders PJ, Mestdagh P, Wower J, Clark MB, Quek XC, Dinger ME.

Nucleic Acids Res. 2017 Jan 4;45(D1):D128-D134. doi: 10.1093/nar/gkw1008. Epub 2016 Oct 28.


An Accelerated Release Study to Evaluate Long-Acting Contraceptive Levonorgestrel-Containing in Situ Forming Depot Systems.

Janagam DR, Wang L, Ananthula S, Johnson JR, Lowe TL.

Pharmaceutics. 2016 Sep 1;8(3). pii: E28. doi: 10.3390/pharmaceutics8030028.


QUEST®: A Data-Driven Collaboration to Improve Quality, Efficiency, Safety, and Transparency in Acute Care.

Crimmins MM, Lowe TJ, Barrington M, Kaylor C, Phipps T, Le-Roy C, Brooks T, Jones M, Martin J.

Jt Comm J Qual Patient Saf. 2016 Jun;42(6):247-53.


tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes.

Lowe TM, Chan PP.

Nucleic Acids Res. 2016 Jul 8;44(W1):W54-7. doi: 10.1093/nar/gkw413. Epub 2016 May 12.


Optimal Contrast Agent Staining of Ligaments and Tendons for X-Ray Computed Tomography.

Balint R, Lowe T, Shearer T.

PLoS One. 2016 Apr 14;11(4):e0153552. doi: 10.1371/journal.pone.0153552. eCollection 2016.


Ralstonia solanacearum lipopeptide induces chlamydospore development in fungi and facilitates bacterial entry into fungal tissues.

Spraker JE, Sanchez LM, Lowe TM, Dorrestein PC, Keller NP.

ISME J. 2016 Sep;10(9):2317-30. doi: 10.1038/ismej.2016.32. Epub 2016 Mar 4.


In planta comparative transcriptomics of host-adapted strains of Ralstonia solanacearum.

Ailloud F, Lowe TM, Robène I, Cruveiller S, Allen C, Prior P.

PeerJ. 2016 Jan 5;4:e1549. doi: 10.7717/peerj.1549. eCollection 2016.


Effect of bulk microstructure of commercially pure titanium on surface characteristics and fatigue properties after surface modification by sand blasting and acid-etching.

Medvedev AE, Ng HP, Lapovok R, Estrin Y, Lowe TC, Anumalasetty VN.

J Mech Behav Biomed Mater. 2016 Apr;57:55-68. doi: 10.1016/j.jmbbm.2015.11.035. Epub 2015 Dec 7.


GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes.

Chan PP, Lowe TM.

Nucleic Acids Res. 2016 Jan 4;44(D1):D184-9. doi: 10.1093/nar/gkv1309. Epub 2015 Dec 15.


Subconjunctivally Implanted Hydrogels for Sustained Insulin Release to Reduce Retinal Cell Apoptosis in Diabetic Rats.

Imai H, Misra GP, Wu L, Janagam DR, Gardner TW, Lowe TL.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7839-46. doi: 10.1167/iovs.15-16998.


Visual Analytics for Development and Evaluation of Order Selection Criteria for Autoregressive Processes.

Löwe T, Förster EC, Albuquerque G, Kreiss JP, Magnor M.

IEEE Trans Vis Comput Graph. 2016 Jan;22(1):151-9. doi: 10.1109/TVCG.2015.2467612.


Morphine-induced antinociception and reward in "humanized" mice expressing the mu opioid receptor A118G polymorphism.

Henderson-Redmond AN, Yuill MB, Lowe TE, Kline AM, Zee ML, Guindon J, Morgan DJ.

Brain Res Bull. 2016 May;123:5-12. doi: 10.1016/j.brainresbull.2015.10.007. Epub 2015 Oct 28.


Congestive Heart Failure Leads to Prolongation of the PR Interval and Atrioventricular Junction Enlargement and Ion Channel Remodelling in the Rabbit.

Nikolaidou T, Cai XJ, Stephenson RS, Yanni J, Lowe T, Atkinson AJ, Jones CB, Sardar R, Corno AF, Dobrzynski H, Withers PJ, Jarvis JC, Hart G, Boyett MR.

PLoS One. 2015 Oct 28;10(10):e0141452. doi: 10.1371/journal.pone.0141452. eCollection 2015.


Development and validation of sensitive LC/MS/MS method for quantitative bioanalysis of levonorgestrel in rat plasma and application to pharmacokinetics study.

Ananthula S, Janagam DR, Jamalapuram S, Johnson JR, Mandrell TD, Lowe TL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:47-53. doi: 10.1016/j.jchromb.2015.09.006. Epub 2015 Sep 11.


Stochastic predictors from the DXA scans of human lumbar vertebrae are correlated with the microarchitecture parameters of trabecular bone.

Dong XN, Pinninti R, Tvinnereim A, Lowe T, Di Paolo D, Shirvaikar M.

J Biomech. 2015 Sep 18;48(12):2968-75. doi: 10.1016/j.jbiomech.2015.07.041. Epub 2015 Aug 12.


C/D box sRNA-guided 2'-O-methylation patterns of archaeal rRNA molecules.

Dennis PP, Tripp V, Lui L, Lowe T, Randau L.

BMC Genomics. 2015 Aug 22;16:632. doi: 10.1186/s12864-015-1839-z.


Draft De Novo Transcriptome of the Rat Kangaroo Potorous tridactylus as a Tool for Cell Biology.

Udy DB, Voorhies M, Chan PP, Lowe TM, Dumont S.

PLoS One. 2015 Aug 7;10(8):e0134738. doi: 10.1371/journal.pone.0134738. eCollection 2015.

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