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Items: 22

1.

Ocular pharmacokinetics of mapracorat, a novel, selective glucocorticoid receptor agonist, in rabbits and monkeys.

Proksch JW, Lowe ER, Ward KW.

Drug Metab Dispos. 2011 Jul;39(7):1181-7. doi: 10.1124/dmd.111.039099. Epub 2011 Mar 25.

PMID:
21441467
2.

In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol.

Zhang F, Lowe ER, Rick DL, Qiu X, Leibold E, Cruzan G, Bartels MJ.

Xenobiotica. 2011 Jan;41(1):6-23. doi: 10.3109/00498254.2010.523735. Epub 2010 Oct 7.

PMID:
20925585
3.

The effect of plasma lipids on the pharmacokinetics of chlorpyrifos and the impact on interpretation of blood biomonitoring data.

Lowe ER, Poet TS, Rick DL, Marty MS, Mattsson JL, Timchalk C, Bartels MJ.

Toxicol Sci. 2009 Apr;108(2):258-72. doi: 10.1093/toxsci/kfp034. Epub 2009 Feb 17.

PMID:
19223661
4.

Dynamic changes in lipids and proteins of maternal, fetal, and pup blood and milk during perinatal development in CD and Wistar rats.

McMullin TS, Lowe ER, Bartels MJ, Marty MS.

Toxicol Sci. 2008 Oct;105(2):260-74. doi: 10.1093/toxsci/kfn124. Epub 2008 Jun 30.

PMID:
18593729
5.

Investigations of oxidative stress, antioxidant response, and protein binding in chlorpyrifos exposed rat neuronal PC12 cells.

Geter DR, Kan HL, Lowe ER, Rick DL, Charles GD, Gollapudi BB, Mattsson JL.

Toxicol Mech Methods. 2008;18(1):17-23. doi: 10.1080/15376510701389530.

PMID:
20020887
6.

Pharmacokinetics and bioavailability of diisopropanolamine (DIPA) in rats following intravenous or dermal application.

Saghir SA, Frantz SW, Spence MW, Nolan RJ, Lowe ER, Rick DL, Bartels MJ.

Food Chem Toxicol. 2007 Oct;45(10):2047-56. Epub 2007 May 18.

PMID:
17583405
7.
8.

Naturally occurring neuronal NO-synthase inactivators found in Nicotiana tabacum (Solanaceae) and other plants.

Lowe ER, Everett AC, Lau M, Dunbar AY, Michener D, Osawa Y.

Phytomedicine. 2007 May;14(5):344-52. Epub 2006 Nov 3.

PMID:
17084601
9.

Tetrahydrobiopterin protects against guanabenz-mediated inhibition of neuronal nitric-oxide synthase in vitro and in vivo.

Dunbar AY, Jenkins GJ, Jianmongkol S, Nakatsuka M, Lowe ER, Lau M, Osawa Y.

Drug Metab Dispos. 2006 Sep;34(9):1448-56. Epub 2006 May 31.

PMID:
16738031
10.

Tetrahydrobiopterin depletion and ubiquitylation of neuronal nitric oxide synthase.

Kamada Y, Jenkins GJ, Lau M, Dunbar AY, Lowe ER, Osawa Y.

Brain Res Mol Brain Res. 2005 Dec 7;142(1):19-27. Epub 2005 Oct 10.

PMID:
16216381
11.

Indirect detection of substituted phenols and cannabis based on the electrochemical adaptation of the Gibbs reaction.

Lowe ER, Banks CE, Compton RG.

Anal Bioanal Chem. 2005 Oct;383(3):523-31. Epub 2005 Oct 19.

PMID:
16136302
12.

Voltammetric sizing of inert particles.

Davies TJ, Lowe ER, Wilkins SJ, Compton RG.

Chemphyschem. 2005 Jul 11;6(7):1340-7.

PMID:
15942972
13.

Gas sensing using edge-plane pyrolytic-graphite electrodes: electrochemical reduction of chlorine.

Lowe ER, Banks CE, Compton RG.

Anal Bioanal Chem. 2005 Jun;382(4):1169-74. Epub 2005 May 10.

PMID:
15883786
14.

Time-dependent inhibition and tetrahydrobiopterin depletion of endothelial nitric-oxide synthase caused by cigarettes.

Lowe ER, Everett AC, Lee AJ, Lau M, Dunbar AY, Berka V, Tsai AL, Osawa Y.

Drug Metab Dispos. 2005 Jan;33(1):131-8. Epub 2004 Oct 6.

PMID:
15470159
15.

Ubiquitination and degradation of neuronal nitric-oxide synthase in vitro: dimer stabilization protects the enzyme from proteolysis.

Dunbar AY, Kamada Y, Jenkins GJ, Lowe ER, Billecke SS, Osawa Y.

Mol Pharmacol. 2004 Oct;66(4):964-9. Epub 2004 Jul 2.

PMID:
15235101
16.

The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex.

Morishima Y, Kanelakis KC, Murphy PJ, Lowe ER, Jenkins GJ, Osawa Y, Sunahara RK, Pratt WB.

J Biol Chem. 2003 Dec 5;278(49):48754-63. Epub 2003 Sep 24.

17.

Metabolism-based inactivation of neuronal nitric-oxide synthase by components of cigarette and cigarette smoke.

Demady DR, Lowe ER, Everett AC, Billecke SS, Kamada Y, Dunbar AY, Osawa Y.

Drug Metab Dispos. 2003 Jul;31(7):932-7.

PMID:
12814971
18.

Proteolytic degradation of nitric oxide synthase: effect of inhibitors and role of hsp90-based chaperones.

Osawa Y, Lowe ER, Everett AC, Dunbar AY, Billecke SS.

J Pharmacol Exp Ther. 2003 Feb;304(2):493-7. Review.

PMID:
12538799
19.

Alteration of the heme prosthetic group of neuronal nitric-oxide synthase during inactivation by N(G)-amino-L-arginine in vitro and in vivo.

Vuletich JL, Lowe ER, Jianmongkol S, Kamada Y, Kent UM, Bender AT, Demady DR, Hollenberg PF, Osawa Y.

Mol Pharmacol. 2002 Jul;62(1):110-8.

PMID:
12065761
20.

hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any action of hsp90.

Billecke SS, Bender AT, Kanelakis KC, Murphy PJ, Lowe ER, Kamada Y, Pratt WB, Osawa Y.

J Biol Chem. 2002 Jun 7;277(23):20504-9. Epub 2002 Mar 28.

21.

Effects of azimilide and d,l-sotalol on the heart rate and blood pressure response to isoproterenol in anesthetized rats.

Mittelstadt SW, Maynard AE, Benn DR, Lowe ER, Kostreva DR.

Cardiovasc Drugs Ther. 1997 Sep;11(4):591-8.

PMID:
9358964
22.

Influence of histaminase inhibitors on certain pharmacological effects of histamine.

ANGELAKOS ET, LOWE ER.

Arch Int Pharmacodyn Ther. 1958 Nov-Dec;117(3-4):277-83. No abstract available.

PMID:
13606937

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