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Items: 12


Isolation and characterization of camelid single-domain antibodies against HER2.

Hussack G, Raphael S, Lowden MJ, Henry KA.

BMC Res Notes. 2018 Dec 5;11(1):866. doi: 10.1186/s13104-018-3955-8.


Oxford nanopore sequencing enables rapid discovery of single-domain antibodies from phage display libraries.

Lowden MJ, Henry KA.

Biotechniques. 2018 Dec;65(6):351-356. doi: 10.2144/btn-2018-0123.


Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human VH/VL Single-Domain Antibodies from In Vitro Display Libraries.

Henry KA, Kim DY, Kandalaft H, Lowden MJ, Yang Q, Schrag JD, Hussack G, MacKenzie CR, Tanha J.

Front Immunol. 2017 Dec 12;8:1759. doi: 10.3389/fimmu.2017.01759. eCollection 2017.


A disulfide-stabilized human VL single-domain antibody library is a source of soluble and highly thermostable binders.

Henry KA, Kandalaft H, Lowden MJ, Rossotti MA, van Faassen H, Hussack G, Durocher Y, Kim DY, Tanha J.

Mol Immunol. 2017 Oct;90:190-196. doi: 10.1016/j.molimm.2017.07.006. Epub 2017 Aug 15.


A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections.

Ferreira RB, Valdez Y, Coombes BK, Sad S, Gouw JW, Brown EM, Li Y, Grassl GA, Antunes LC, Gill N, Truong M, Scholz R, Reynolds LA, Krishnan L, Zafer AA, Sal-Man N, Lowden MJ, Auweter SD, Foster LJ, Finlay BB.

mBio. 2015 Sep 22;6(5):e01421-15. doi: 10.1128/mBio.01421-15.


Functional and structural diversity in GH62 α-L-arabinofuranosidases from the thermophilic fungus Scytalidium thermophilum.

Kaur AP, Nocek BP, Xu X, Lowden MJ, Leyva JF, Stogios PJ, Cui H, Di Leo R, Powlowski J, Tsang A, Savchenko A.

Microb Biotechnol. 2015 May;8(3):419-33. doi: 10.1111/1751-7915.12168. Epub 2014 Sep 29.


Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partners.

Auweter SD, Bhavsar AP, de Hoog CL, Li Y, Chan YA, van der Heijden J, Lowden MJ, Coombes BK, Rogers LD, Stoynov N, Foster LJ, Finlay BB.

J Biol Chem. 2011 Jul 8;286(27):24023-35. doi: 10.1074/jbc.M111.224600. Epub 2011 May 12.


Salmonella phage ST64B encodes a member of the SseK/NleB effector family.

Brown NF, Coombes BK, Bishop JL, Wickham ME, Lowden MJ, Gal-Mor O, Goode DL, Boyle EC, Sanderson KL, Finlay BB.

PLoS One. 2011 Mar 18;6(3):e17824. doi: 10.1371/journal.pone.0017824.


Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes.

Lowden MJ, Skorupski K, Pellegrini M, Chiorazzo MG, Taylor RK, Kull FJ.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2860-5. doi: 10.1073/pnas.0915021107. Epub 2010 Feb 1.


Pathogenic adaptation of intracellular bacteria by rewiring a cis-regulatory input function.

Osborne SE, Walthers D, Tomljenovic AM, Mulder DT, Silphaduang U, Duong N, Lowden MJ, Wickham ME, Waller RF, Kenney LJ, Coombes BK.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3982-7. doi: 10.1073/pnas.0811669106. Epub 2009 Feb 20.


SseL is a salmonella-specific translocated effector integrated into the SsrB-controlled salmonella pathogenicity island 2 type III secretion system.

Coombes BK, Lowden MJ, Bishop JL, Wickham ME, Brown NF, Duong N, Osborne S, Gal-Mor O, Finlay BB.

Infect Immun. 2007 Feb;75(2):574-80. Epub 2006 Dec 11.


Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid.

Coombes BK, Wickham ME, Lowden MJ, Brown NF, Finlay BB.

Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17460-5. Epub 2005 Nov 21.

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