Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 210

1.

Reduced Stability and pH-Dependent Activity of a Common Obesity-Linked PCSK1 Polymorphism, N221D.

Jarvela TS, Shakya M, Bachor T, White A, Low MJ, Lindberg I.

Endocrinology. 2019 Nov 1;160(11):2630-2645. doi: 10.1210/en.2019-00418.

PMID:
31504391
2.

Cross-sectional study of perceptions of qualities of a good medical teacher among medical students from first year to final year.

Low MJW, Khoo KSM, Kuan WS, Ooi SBS.

Singapore Med J. 2019 Aug 16. doi: 10.11622/smedj.2019097. [Epub ahead of print]

3.

Nuclear transcriptional changes in hypothalamus of Pomc enhancer knockout mice after excessive alcohol drinking.

Zhou Y, Liang Y, Low MJ, Kreek MJ.

Genes Brain Behav. 2019 Nov;18(8):e12600. doi: 10.1111/gbb.12600. Epub 2019 Aug 8.

PMID:
31339663
4.

Analysis of Motor Function in the Tg4-42 Mouse Model of Alzheimer's Disease.

Wagner JM, Sichler ME, Schleicher EM, Franke TN, Irwin C, Löw MJ, Beindorff N, Bouter C, Bayer TA, Bouter Y.

Front Behav Neurosci. 2019 May 17;13:107. doi: 10.3389/fnbeh.2019.00107. eCollection 2019.

5.

Prolonged Cannabidiol Treatment Lacks on Detrimental Effects on Memory, Motor Performance and Anxiety in C57BL/6J Mice.

Schleicher EM, Ott FW, Müller M, Silcher B, Sichler ME, Löw MJ, Wagner JM, Bouter Y.

Front Behav Neurosci. 2019 May 7;13:94. doi: 10.3389/fnbeh.2019.00094. eCollection 2019.

6.

Sex differences in the effect of bupropion and naltrexone combination on alcohol drinking in mice.

Zhou Y, Leri F, Low MJ, Kreek MJ.

Pharmacol Biochem Behav. 2019 Jun;181:28-36. doi: 10.1016/j.pbb.2019.04.004. Epub 2019 Apr 13.

PMID:
30991059
7.

Selective Restoration of Pomc Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network.

Jones GL, Wittmann G, Yokosawa EB, Yu H, Mercer AJ, Lechan RM, Low MJ.

eNeuro. 2019 Apr 1;6(2). pii: ENEURO.0400-18.2019. doi: 10.1523/ENEURO.0400-18.2019. eCollection 2019 Mar-Apr.

8.

Pre- and Apnoeic high flow oxygenation for RApid sequence intubation in The Emergency department (Pre-AeRATE): study protocol for a multicentre, randomised controlled trial.

Chua MT, Khan FA, Ng WM, Lu Q, Low MJW, Yau YW, Punyadasa A, Kuan WS.

Trials. 2019 Apr 4;20(1):195. doi: 10.1186/s13063-019-3305-8.

9.

The Homeodomain Transcription Factor NKX2.1 Is Essential for the Early Specification of Melanocortin Neuron Identity and Activates Pomc Expression in the Developing Hypothalamus.

Orquera DP, Tavella MB, de Souza FSJ, Nasif S, Low MJ, Rubinstein M.

J Neurosci. 2019 May 22;39(21):4023-4035. doi: 10.1523/JNEUROSCI.2924-18.2019. Epub 2019 Mar 18.

PMID:
30886014
10.

Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice.

Tooke BP, Yu H, Adams JM, Jones GL, Sutton-Kennedy T, Mundada L, Qi NR, Low MJ, Chhabra KH.

Mol Metab. 2019 Feb;20:194-204. doi: 10.1016/j.molmet.2018.11.004. Epub 2018 Nov 20.

11.

Ruboxistaurin Reduces Cocaine-Stimulated Increases in Extracellular Dopamine by Modifying Dopamine-Autoreceptor Activity.

Zestos AG, Carpenter C, Kim Y, Low MJ, Kennedy RT, Gnegy ME.

ACS Chem Neurosci. 2019 Apr 17;10(4):1960-1969. doi: 10.1021/acschemneuro.8b00259. Epub 2018 Nov 8.

PMID:
30384585
12.

Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.

Kim GH, Shi G, Somlo DR, Haataja L, Song S, Long Q, Nillni EA, Low MJ, Arvan P, Myers MG Jr, Qi L.

J Clin Invest. 2018 Mar 1;128(3):1125-1140. doi: 10.1172/JCI96420. Epub 2018 Feb 19.

13.

17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior.

Steyn FJ, Ngo ST, Chen VP, Bailey-Downs LC, Xie TY, Ghadami M, Brimijoin S, Freeman WM, Rubinstein M, Low MJ, Stout MB.

Aging Cell. 2018 Feb;17(1). doi: 10.1111/acel.12703. Epub 2017 Nov 23.

14.

V1b Receptor Antagonist SSR149415 and Naltrexone Synergistically Decrease Excessive Alcohol Drinking in Male and Female Mice.

Zhou Y, Rubinstein M, Low MJ, Kreek MJ.

Alcohol Clin Exp Res. 2018 Jan;42(1):195-205. doi: 10.1111/acer.13544. Epub 2017 Nov 28.

15.

Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice.

Chhabra KH, Morgan DA, Tooke BP, Adams JM, Rahmouni K, Low MJ.

Mol Metab. 2017 Oct;6(10):1274-1285. doi: 10.1016/j.molmet.2017.07.005. Epub 2017 Jul 17.

16.

Lorcaserin improves glycemic control via a melanocortin neurocircuit.

Burke LK, Ogunnowo-Bada E, Georgescu T, Cristiano C, de Morentin PBM, Valencia Torres L, D'Agostino G, Riches C, Heeley N, Ruan Y, Rubinstein M, Low MJ, Myers MG, Rochford JJ, Evans ML, Heisler LK.

Mol Metab. 2017 Oct;6(10):1092-1102. doi: 10.1016/j.molmet.2017.07.004. Epub 2017 Jul 21.

17.

Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.

Sundaresan S, Meininger CA, Kang AJ, Photenhauer AL, Hayes MM, Sahoo N, Grembecka J, Cierpicki T, Ding L, Giordano TJ, Else T, Madrigal DJ, Low MJ, Campbell F, Baker AM, Xu H, Wright NA, Merchant JL.

Gastroenterology. 2017 Dec;153(6):1555-1567.e15. doi: 10.1053/j.gastro.2017.08.038. Epub 2017 Aug 30.

18.

Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity.

Rubinstein M, Low MJ.

FEBS Lett. 2017 Sep;591(17):2593-2606. doi: 10.1002/1873-3468.12776. Epub 2017 Aug 20. Review.

19.

Not All Mice Are the Same: Standardization of Animal Research Data Presentation.

Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM Jr, Turner JR.

Cell Mol Gastroenterol Hepatol. 2016 May 6;2(4):391-393. doi: 10.1016/j.jcmgh.2016.04.001. eCollection 2016 Jul. No abstract available.

20.

Hypothalamic-specific proopiomelanocortin deficiency reduces alcohol drinking in male and female mice.

Zhou Y, Rubinstein M, Low MJ, Kreek MJ.

Genes Brain Behav. 2017 Apr;16(4):449-461. doi: 10.1111/gbb.12362. Epub 2017 Jan 17.

21.

Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity.

Chhabra KH, Adams JM, Jones GL, Yamashita M, Schlapschy M, Skerra A, Rubinstein M, Low MJ.

Mol Metab. 2016 Aug 5;5(10):869-881. doi: 10.1016/j.molmet.2016.07.012. eCollection 2016 Oct.

22.

Neuroendocrinology: New hormone treatment for obesity caused by POMC-deficiency.

Low MJ.

Nat Rev Endocrinol. 2016 Nov;12(11):627-628. doi: 10.1038/nrendo.2016.156. Epub 2016 Sep 23. No abstract available.

PMID:
27658726
23.

Essential function of the transcription factor Rax in the early patterning of the mammalian hypothalamus.

Orquera DP, Nasif S, Low MJ, Rubinstein M, de Souza FSJ.

Dev Biol. 2016 Aug 1;416(1):212-224. doi: 10.1016/j.ydbio.2016.05.021. Epub 2016 May 19.

24.

Not all mice are the same: Standardization of animal research data presentation.

Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM Jr, Turner JR.

Hepatology. 2016 Jun;63(6):1752-4. doi: 10.1002/hep.28608. No abstract available.

PMID:
27205897
25.

Somatostatin triggers rhythmic electrical firing in hypothalamic GHRH neurons.

Osterstock G, Mitutsova V, Barre A, Granier M, Fontanaud P, Chazalon M, Carmignac D, Robinson IC, Low MJ, Plesnila N, Hodson DJ, Mollard P, Méry PF.

Sci Rep. 2016 Apr 13;6:24394. doi: 10.1038/srep24394.

26.

Not All Mice Are the Same: Standardization of Animal Research Data Presentation.

Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM Jr, Turner JR.

Gastroenterology. 2016 Jun;150(7):1503-1504. doi: 10.1053/j.gastro.2016.03.034. Epub 2016 Apr 8. No abstract available.

PMID:
27063865
27.

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons.

Burke LK, Doslikova B, D'Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, Low MJ, Rochford JJ, Myers MG, Evans ML, Heisler LK.

Mol Metab. 2016 Jan 22;5(3):245-252. doi: 10.1016/j.molmet.2016.01.005. eCollection 2016 Mar.

28.

Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria.

Chhabra KH, Adams JM, Fagel B, Lam DD, Qi N, Rubinstein M, Low MJ.

Diabetes. 2016 Mar;65(3):660-72. doi: 10.2337/db15-0804. Epub 2015 Oct 14.

29.

Rapid Glucocorticoid Feedback Inhibition of ACTH Secretion Involves Ligand-Dependent Membrane Association of Glucocorticoid Receptors.

Deng Q, Riquelme D, Trinh L, Low MJ, Tomić M, Stojilkovic S, Aguilera G.

Endocrinology. 2015 Sep;156(9):3215-27. doi: 10.1210/EN.2015-1265. Epub 2015 Jun 29.

31.

Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood.

Nasif S, de Souza FS, González LE, Yamashita M, Orquera DP, Low MJ, Rubinstein M.

Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):E1861-70. doi: 10.1073/pnas.1500672112. Epub 2015 Mar 30.

32.

Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold.

Lam DD, de Souza FS, Nasif S, Yamashita M, López-Leal R, Otero-Corchon V, Meece K, Sampath H, Mercer AJ, Wardlaw SL, Rubinstein M, Low MJ.

PLoS Genet. 2015 Feb 11;11(2):e1004935. doi: 10.1371/journal.pgen.1004935. eCollection 2015 Feb. Erratum in: PLoS Genet. 2015 Apr;11(4):e1005133.

33.

Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism.

Lam DD, Attard CA, Mercer AJ, Myers MG Jr, Rubinstein M, Low MJ.

Endocrinology. 2015 Apr;156(4):1292-302. doi: 10.1210/en.2014-1373. Epub 2015 Jan 16.

34.

Somatostatin is essential for the sexual dimorphism of GH secretion, corticosteroid-binding globulin production, and corticosterone levels in mice.

Adams JM, Otero-Corchon V, Hammond GL, Veldhuis JD, Qi N, Low MJ.

Endocrinology. 2015 Mar;156(3):1052-65. doi: 10.1210/en.2014-1429. Epub 2014 Dec 31.

35.

Glucose rapidly induces different forms of excitatory synaptic plasticity in hypothalamic POMC neurons.

Hu J, Jiang L, Low MJ, Rui L.

PLoS One. 2014 Aug 15;9(8):e105080. doi: 10.1371/journal.pone.0105080. eCollection 2014.

36.

5-HT obesity medication efficacy via POMC activation is maintained during aging.

Burke LK, Doslikova B, D'Agostino G, Garfield AS, Farooq G, Burdakov D, Low MJ, Rubinstein M, Evans ML, Billups B, Heisler LK.

Endocrinology. 2014 Oct;155(10):3732-8. doi: 10.1210/en.2014-1223. Epub 2014 Jul 22.

37.

Adolescent growth: genes, hormones and the peer group. Proceedings of the 20th Aschauer Soiree, held at Glücksburg castle, Germany, 15th to 17th November 2013.

Hermanussen M, Meitinger T, Veldhuis JD, Low MJ, Pfäffle R, Staub K, Panczak R, Groth D, Brabec M, von Salisch M, Loh CP, Tassenaar V, Scheffler C, Mumm R, Godina E, Lehmann A, Tutkuviene J, Gervickaite S, Nierop AF, Holmgren A, Assmann C, van Buuren S, Koziel S, Zadzińska E, Varela-Silva I, Vignerová J, Salama E, El-Shabrawi M, Huiji A, Satake T, Bogin B.

Pediatr Endocrinol Rev. 2014 Mar;11(3):341-53.

PMID:
24716402
38.

Temporal changes in nutritional state affect hypothalamic POMC peptide levels independently of leptin in adult male mice.

Mercer AJ, Stuart RC, Attard CA, Otero-Corchon V, Nillni EA, Low MJ.

Am J Physiol Endocrinol Metab. 2014 Apr 15;306(8):E904-15. doi: 10.1152/ajpendo.00540.2013. Epub 2014 Feb 11.

39.

Enhancer turnover and conserved regulatory function in vertebrate evolution.

Domené S, Bumaschny VF, de Souza FS, Franchini LF, Nasif S, Low MJ, Rubinstein M.

Philos Trans R Soc Lond B Biol Sci. 2013 Nov 11;368(1632):20130027. doi: 10.1098/rstb.2013.0027. Print 2013 Dec 19.

40.

Central dopamine D2 receptors regulate growth-hormone-dependent body growth and pheromone signaling to conspecific males.

Noaín D, Pérez-Millán MI, Bello EP, Luque GM, Casas Cordero R, Gelman DM, Peper M, Tornadu IG, Low MJ, Becú-Villalobos D, Rubinstein M.

J Neurosci. 2013 Mar 27;33(13):5834-42. doi: 10.1523/JNEUROSCI.5673-12.2013.

41.

Unraveling the central proopiomelanocortin neural circuits.

Mercer AJ, Hentges ST, Meshul CK, Low MJ.

Front Neurosci. 2013 Feb 22;7:19. doi: 10.3389/fnins.2013.00019. eCollection 2013.

42.

Constitutive TLR4 signalling in intestinal epithelium reduces tumor load by increasing apoptosis in APC(Min/+) mice.

Li Y, Teo WL, Low MJ, Meijer L, Sanderson I, Pettersson S, Greicius G.

Oncogene. 2014 Jan 16;33(3):369-77. doi: 10.1038/onc.2012.581. Epub 2013 Jan 14.

PMID:
23318418
43.

Obesity-programmed mice are rescued by early genetic intervention.

Bumaschny VF, Yamashita M, Casas-Cordero R, Otero-Corchón V, de Souza FS, Rubinstein M, Low MJ.

J Clin Invest. 2012 Nov;122(11):4203-12. doi: 10.1172/JCI62543. Epub 2012 Oct 24.

44.

Mouse models in gastroenterology research.

Low MJ.

Gastroenterology. 2012 Dec;143(6):1410-2. doi: 10.1053/j.gastro.2012.10.011. Epub 2012 Oct 16. No abstract available.

PMID:
23078986
45.

Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can't beat them, join them.

Franchini LF, de Souza FS, Low MJ, Rubinstein M.

Mob Genet Elements. 2012 Mar 1;2(2):106-109.

46.

Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression.

Reilly PT, Teo WL, Low MJ, Amoyo-Brion AA, Dominguez-Brauer C, Elia AJ, Berger T, Greicius G, Pettersson S, Mak TW.

Oncogene. 2013 Mar 7;32(10):1233-9. doi: 10.1038/onc.2012.159. Epub 2012 May 21.

47.

Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons.

Franchini LF, López-Leal R, Nasif S, Beati P, Gelman DM, Low MJ, de Souza FJ, Rubinstein M.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15270-5. doi: 10.1073/pnas.1104997108. Epub 2011 Aug 29. Erratum in: Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20850.

48.

The smoking gun in nicotine-induced anorexia.

Rubinstein M, Low MJ.

Cell Metab. 2011 Aug 3;14(2):145-7. doi: 10.1016/j.cmet.2011.07.006.

49.

Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors.

Bello EP, Mateo Y, Gelman DM, Noaín D, Shin JH, Low MJ, Alvarez VA, Lovinger DM, Rubinstein M.

Nat Neurosci. 2011 Jul 10;14(8):1033-8. doi: 10.1038/nn.2862.

50.

Agnostic about in vivo inverse agonism of agouti-related peptide.

Low MJ.

Endocrinology. 2011 May;152(5):1731-3. doi: 10.1210/en.2011-0232. No abstract available.

Supplemental Content

Support Center