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Items: 20


Quantitative Trait Locus and Integrative Genomics Revealed Candidate Modifier Genes for Ectopic Mineralization in Mouse Models of Pseudoxanthoma Elasticum.

Li Q, Philip VM, Stearns TM, Bubier JA, King BL, Low BE, Wiles MV, Saeidian AH, Sundberg BA, Uitto J, Sundberg JP.

J Invest Dermatol. 2019 Jun 14. pii: S0022-202X(19)31761-0. doi: 10.1016/j.jid.2019.04.023. [Epub ahead of print]


Towards large scale automated cage monitoring - Diurnal rhythm and impact of interventions on in-cage activity of C57BL/6J mice recorded 24/7 with a non-disrupting capacitive-based technique.

Pernold K, Iannello F, Low BE, Rigamonti M, Rosati G, Scavizzi F, Wang J, Raspa M, Wiles MV, Ulfhake B.

PLoS One. 2019 Feb 4;14(2):e0211063. doi: 10.1371/journal.pone.0211063. eCollection 2019.


Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression.

Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD.

FASEB J. 2019 Mar;33(3):3137-3151. doi: 10.1096/fj.201800636R. Epub 2018 Nov 1.


Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3, Is Dependent on the Crb1rd8 Allele.

Chang B, FitzMaurice B, Wang J, Low BE, Wiles MV, Nishina PM.

Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):5127-5139. doi: 10.1167/iovs.18-25046.


RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?

Hosur V, Farley ML, Low BE, Burzenski LM, Shultz LD, Wiles MV.

Front Genet. 2018 Jul 4;9:233. doi: 10.3389/fgene.2018.00233. eCollection 2018.


Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.

Winer BY, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low BE, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais MA, Frankel AS, Chiriboga L, Cullen J, Nahass RG, Lutgehetmann M, Toettcher JE, Wiles MV, Schwartz RE, Ploss A.

Sci Transl Med. 2018 Jun 27;10(447). pii: eaap9328. doi: 10.1126/scitranslmed.aap9328.


Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates.

Li F, Xu R, Low BE, Lin CL, Garcia-Barros M, Schrandt J, Mileva I, Snider A, Luo CK, Jiang XC, Li MS, Hannun YA, Obeid LM, Wiles MV, Mao C.

FASEB J. 2018 Jun;32(6):3058-3069. doi: 10.1096/fj.201700445RR. Epub 2018 Jan 22.


Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice.

Johnson KR, Gagnon LH, Tian C, Longo-Guess CM, Low BE, Wiles MV, Kiernan AE.

Genetics. 2018 Mar;208(3):1165-1179. doi: 10.1534/genetics.117.300447. Epub 2018 Jan 3.


Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.

Hosur V, Low BE, Shultz LD, Wiles MV.

Biol Open. 2017 Aug 15;6(8):1174-1179. doi: 10.1242/bio.026260.


Development of Humanized Mice in the Age of Genome Editing.

Hosur V, Low BE, Avery C, Shultz LD, Wiles MV.

J Cell Biochem. 2017 Oct;118(10):3043-3048. doi: 10.1002/jcb.26002. Epub 2017 May 15.


Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection.

Winer BY, Huang T, Low BE, Avery C, Pais MA, Hrebikova G, Siu E, Chiriboga L, Wiles MV, Ploss A.

Virology. 2017 Feb;502:63-72. doi: 10.1016/j.virol.2016.12.017. Epub 2016 Dec 19.


A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics.

Low BE, Wiles MV.

Methods Mol Biol. 2016;1438:115-22. doi: 10.1007/978-1-4939-3661-8_7. Review.


Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice.

Low BE, Taft RA, Wiles MV.

Methods Mol Biol. 2016;1438:55-66. doi: 10.1007/978-1-4939-3661-8_3.


Simple, Efficient CRISPR-Cas9-Mediated Gene Editing in Mice: Strategies and Methods.

Low BE, Kutny PM, Wiles MV.

Methods Mol Biol. 2016;1438:19-53. doi: 10.1007/978-1-4939-3661-8_2. Review.


Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs.

Roopenian DC, Low BE, Christianson GJ, Proetzel G, Sproule TJ, Wiles MV.

MAbs. 2015;7(2):344-51. doi: 10.1080/19420862.2015.1008345.


Epigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity.

Chow KH, Shin DM, Jenkins MH, Miller EE, Shih DJ, Choi S, Low BE, Philip V, Rybinski B, Bronson RT, Taylor MD, Yun K.

Cancer Res. 2014 Sep 1;74(17):4864-74. doi: 10.1158/0008-5472.CAN-13-3293. Epub 2014 Aug 18.


Correction of the Crb1rd8 allele and retinal phenotype in C57BL/6N mice via TALEN-mediated homology-directed repair.

Low BE, Krebs MP, Joung JK, Tsai SQ, Nishina PM, Wiles MV.

Invest Ophthalmol Vis Sci. 2014 Jan 20;55(1):387-95. doi: 10.1167/iovs.13-13278.


The perfect host: a mouse host embryo facilitating more efficient germ line transmission of genetically modified embryonic stem cells.

Taft RA, Low BE, Byers SL, Murray SA, Kutny P, Wiles MV.

PLoS One. 2013 Jul 2;8(7):e67826. doi: 10.1371/journal.pone.0067826. Print 2013.


Treating depressed and anxious smokers in smoking cessation programs.

Richards CS, Cohen LM, Morrell HE, Watson NL, Low BE.

J Consult Clin Psychol. 2013 Apr;81(2):263-73. doi: 10.1037/a0027793. Epub 2012 Mar 19. Review.


Cancer stem cells are enriched in the side population cells in a mouse model of glioma.

Harris MA, Yang H, Low BE, Mukherjee J, Guha A, Bronson RT, Shultz LD, Israel MA, Yun K.

Cancer Res. 2008 Dec 15;68(24):10051-9. doi: 10.1158/0008-5472.CAN-08-0786. Erratum in: Cancer Res. 2009 Jul 15;69(14):6005. Mukherje, Joydeep [corrected to Mukherjee, Joydeep].

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