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Items: 22


X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation.

Sankaran VG, Ulirsch JC, Tchaikovskii V, Ludwig LS, Wakabayashi A, Kadirvel S, Lindsley RC, Bejar R, Shi J, Lovitch SB, Bishop DF, Steensma DP.

J Clin Invest. 2020 Jan 2;130(1):552. doi: 10.1172/JCI132538. No abstract available.


Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses.

Clement RL, Daccache J, Mohammed MT, Diallo A, Blazar BR, Kuchroo VK, Lovitch SB, Sharpe AH, Sage PT.

Nat Immunol. 2019 Oct;20(10):1360-1371. doi: 10.1038/s41590-019-0472-4. Epub 2019 Sep 2.


Multicenter analysis of outcomes in blastic plasmacytoid dendritic cell neoplasm offers a pretargeted therapy benchmark.

Taylor J, Haddadin M, Upadhyay VA, Grussie E, Mehta-Shah N, Brunner AM, Louissaint A Jr, Lovitch SB, Dogan A, Fathi AT, Stone RM, Tallman MS, Rampal RK, Neuberg DS, Stevenson KE, Horwitz SM, Lane AA.

Blood. 2019 Aug 22;134(8):678-687. doi: 10.1182/blood.2019001144. Epub 2019 Jun 26.


MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma.

Rodig SJ, Gusenleitner D, Jackson DG, Gjini E, Giobbie-Hurder A, Jin C, Chang H, Lovitch SB, Horak C, Weber JS, Weirather JL, Wolchok JD, Postow MA, Pavlick AC, Chesney J, Hodi FS.

Sci Transl Med. 2018 Jul 18;10(450). pii: eaar3342. doi: 10.1126/scitranslmed.aar3342.


Repetitive ischemic injuries to the kidneys result in lymph node fibrosis and impaired healing.

Maarouf OH, Uehara M, Kasinath V, Solhjou Z, Banouni N, Bahmani B, Jiang L, Yilmam OA, Guleria I, Lovitch SB, Grogan JL, Fiorina P, Sage PT, Bromberg JS, McGrath MM, Abdi R.

JCI Insight. 2018 Jul 12;3(13). pii: 120546. doi: 10.1172/jci.insight.120546.


Histiocytic sarcoma: New insights into FNA cytomorphology and molecular characteristics.

Hung YP, Lovitch SB, Qian X.

Cancer Cytopathol. 2017 Aug;125(8):604-614. doi: 10.1002/cncy.21851. Epub 2017 Apr 24.


Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation.

Ron-Harel N, Santos D, Ghergurovich JM, Sage PT, Reddy A, Lovitch SB, Dephoure N, Satterstrom FK, Sheffer M, Spinelli JB, Gygi S, Rabinowitz JD, Sharpe AH, Haigis MC.

Cell Metab. 2016 Jul 12;24(1):104-17. doi: 10.1016/j.cmet.2016.06.007.


Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.

Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR.

J Clin Invest. 2016 Jul 1;126(7):2642-60. doi: 10.1172/JCI85796. Epub 2016 Jun 13.


The Role of Surgical Pathology in Guiding Cancer Immunotherapy.

Lovitch SB, Rodig SJ.

Annu Rev Pathol. 2016 May 23;11:313-41. doi: 10.1146/annurev-pathol-012615-044125. Review.


Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, Arancibia-Cárcamo CV, Sobel RA, Rudensky AY, Kuchroo VK, Freeman GJ, Sharpe AH.

J Exp Med. 2015 Sep 21;212(10):1603-21. doi: 10.1084/jem.20141030. Epub 2015 Sep 14.


A Man in His 40s With Headache, Lethargy, and Altered Mental Status.

McKee KE, Etherton MR, Lovitch SB, Gupta AS, Micalizzi DS, Tierney T, Wadleigh M, Vaitkevicus H.

JAMA Neurol. 2015 Sep;72(9):1061-5. doi: 10.1001/jamaneurol.2015.1375.


X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation.

Sankaran VG, Ulirsch JC, Tchaikovskii V, Ludwig LS, Wakabayashi A, Kadirvel S, Lindsley RC, Bejar R, Shi J, Lovitch SB, Bishop DF, Steensma DP.

J Clin Invest. 2015 Apr;125(4):1665-9. doi: 10.1172/JCI78619. Epub 2015 Feb 23. Erratum in: J Clin Invest. 2020 Jan 2;130(1):552.


The coinhibitory receptor CTLA-4 controls B cell responses by modulating T follicular helper, T follicular regulatory, and T regulatory cells.

Sage PT, Paterson AM, Lovitch SB, Sharpe AH.

Immunity. 2014 Dec 18;41(6):1026-39. doi: 10.1016/j.immuni.2014.12.005. Epub 2014 Dec 5.


SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.

Laurent G, German NJ, Saha AK, de Boer VC, Davies M, Koves TR, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch SB, Sharpe AH, Kurland IJ, Steegborn C, Gygi SP, Muoio DM, Ruderman NB, Haigis MC.

Mol Cell. 2013 Jun 6;50(5):686-98. doi: 10.1016/j.molcel.2013.05.012.


Activation of type B T cells after protein immunization reveals novel pathways of in vivo presentation of peptides.

Lovitch SB, Esparza TJ, Schweitzer G, Herzog J, Unanue ER.

J Immunol. 2007 Jan 1;178(1):122-33.


The wide diversity and complexity of peptides bound to class II MHC molecules.

Suri A, Lovitch SB, Unanue ER.

Curr Opin Immunol. 2006 Feb;18(1):70-7. Epub 2005 Nov 28. Review.


Conformational isomers of a peptide-class II major histocompatibility complex.

Lovitch SB, Unanue ER.

Immunol Rev. 2005 Oct;207:293-313. Review.


T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM.

Pu Z, Lovitch SB, Bikoff EK, Unanue ER.

Immunity. 2004 Apr;20(4):467-76.


APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells.

Lovitch SB, Walters JJ, Gross ML, Unanue ER.

J Immunol. 2003 Apr 15;170(8):4155-60.

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