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Items: 1 to 50 of 281

1.

Predictors of modern contraceptive use among women and men in Uganda: a population-level analysis.

Namasivayam A, Lovell S, Namutamba S, Schluter PJ.

BMJ Open. 2020 Feb 28;10(2):e034675. doi: 10.1136/bmjopen-2019-034675.

2.

Variability in Gene Expression is Associated with Incomplete Penetrance in Inherited Eye Disorders.

Green DJ, Sallah SR, Ellingford JM, Lovell SC, Sergouniotis PI.

Genes (Basel). 2020 Feb 9;11(2). pii: E179. doi: 10.3390/genes11020179.

3.

Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2.

Duncan CJA, Thompson BJ, Chen R, Rice GI, Gothe F, Young DF, Lovell SC, Shuttleworth VG, Brocklebank V, Corner B, Skelton AJ, Bondet V, Coxhead J, Duffy D, Fourrage C, Livingston JH, Pavaine J, Cheesman E, Bitetti S, Grainger A, Acres M, Innes BA, Mikulasova A, Sun R, Hussain R, Wright R, Wynn R, Zarhrate M, Zeef LAH, Wood K, Hughes SM, Harris CL, Engelhardt KR, Crow YJ, Randall RE, Kavanagh D, Hambleton S, Briggs TA.

Sci Immunol. 2019 Dec 13;4(42). pii: eaav7501. doi: 10.1126/sciimmunol.aav7501.

PMID:
31836668
4.

Faecal neutrophil elastase-antiprotease balance reflects colitis severity.

Barry R, Ruano-Gallego D, Radhakrishnan ST, Lovell S, Yu L, Kotik O, Glegola-Madejska I, Tate EW, Choudhary JS, Williams HRT, Frankel G.

Mucosal Immunol. 2020 Mar;13(2):322-333. doi: 10.1038/s41385-019-0235-4. Epub 2019 Nov 26.

5.

Consistent condom use and its predictors among female sexual Partners of People who Inject Drugs in Klang Valley, Malaysia.

Abdul Manaf R, Dickson N, Lovell S, Ibrahim F.

BMC Public Health. 2019 Nov 7;19(1):1473. doi: 10.1186/s12889-019-7855-1.

6.

Glecaprevir/pibrentasvir for 8 weeks in treatment-naïve patients with chronic HCV genotypes 1-6 and compensated cirrhosis: The EXPEDITION-8 trial.

Brown RS Jr, Buti M, Rodrigues L, Chulanov V, Chuang WL, Aguilar H, Horváth G, Zuckerman E, Carrion BR, Rodriguez-Perez F, Urbánek P, Abergel A, Cohen E, Lovell SS, Schnell G, Lin CW, Zha J, Wang S, Trinh R, Mensa FJ, Burroughs M, Felizarta F.

J Hepatol. 2020 Mar;72(3):441-449. doi: 10.1016/j.jhep.2019.10.020. Epub 2019 Nov 2.

7.

Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulation.

Soules KR, Dmitriev A, LaBrie SD, Dimond ZE, May BH, Johnson DK, Zhang Y, Battaile KP, Lovell S, Hefty PS.

Mol Microbiol. 2020 Jan;113(1):68-88. doi: 10.1111/mmi.14401. Epub 2019 Nov 7.

PMID:
31637787
8.

Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia.

Vaz FM, McDermott JH, Alders M, Wortmann SB, Kölker S, Pras-Raves ML, Vervaart MAT, van Lenthe H, Luyf ACM, Elfrink HL, Metcalfe K, Cuvertino S, Clayton PE, Yarwood R, Lowe MP, Lovell S, Rogers RC; Deciphering Developmental Disorders Study, van Kampen AHC, Ruiter JPN, Wanders RJA, Ferdinandusse S, van Weeghel M, Engelen M, Banka S.

Brain. 2019 Nov 1;142(11):3382-3397. doi: 10.1093/brain/awz291.

9.

The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.

Kryza T, Bock N, Lovell S, Rockstroh A, Lehman ML, Lesner A, Panchadsaram J, Silva LM, Srinivasan S, Snell CE, Williams ED, Fazli L, Gleave M, Batra J, Nelson C, Tate EW, Harris J, Hooper JD, Clements JA.

Mol Oncol. 2020 Jan;14(1):105-128. doi: 10.1002/1878-0261.12587. Epub 2019 Nov 28.

10.

A Zika Reference Panel for Molecular-Based Diagnostic Devices as a US Food and Drug Administration Response Tool to a Public Health Emergency.

García M, Fares-Gusmao R, Sapsford K, Chancey C, Grinev A, Lovell S, Scherf U, Rios M.

J Mol Diagn. 2019 Nov;21(6):1025-1033. doi: 10.1016/j.jmoldx.2019.06.004. Epub 2019 Oct 15.

11.

Reliable Generation of Native-Like Decoys Limits Predictive Ability in Fragment-Based Protein Structure Prediction.

Kandathil SM, Garza-Fabre M, Handl J, Lovell SC.

Biomolecules. 2019 Oct 15;9(10). pii: E612. doi: 10.3390/biom9100612.

12.

Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.

Lan L, Xing M, Kashipathy M, Douglas J, Gao P, Battaile K, Hanzlik R, Lovell S, Xu L.

Proteins. 2020 Apr;88(4):573-583. doi: 10.1002/prot.25836. Epub 2019 Oct 29.

13.

FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science.

Sichtig H, Minogue T, Yan Y, Stefan C, Hall A, Tallon L, Sadzewicz L, Nadendla S, Klimke W, Hatcher E, Shumway M, Aldea DL, Allen J, Koehler J, Slezak T, Lovell S, Schoepp R, Scherf U.

Nat Commun. 2019 Jul 25;10(1):3313. doi: 10.1038/s41467-019-11306-6.

14.

Improved contraceptive use among women and men in Uganda between 1995-2016: A repeated cross-sectional population study.

Namasivayam A, Lovell S, Namutamba S, Schluter PJ.

PLoS One. 2019 Jul 18;14(7):e0219963. doi: 10.1371/journal.pone.0219963. eCollection 2019.

15.

Crystal structures of the naturally fused CS and cytochrome b5 reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+ nicotinamide ring.

Benson DR, Lovell S, Mehzabeen N, Galeva N, Cooper A, Gao P, Battaile KP, Zhu H.

Acta Crystallogr D Struct Biol. 2019 Jul 1;75(Pt 7):628-638. doi: 10.1107/S205979831900754X. Epub 2019 Jun 26.

PMID:
31282472
16.

Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Adolescents With Chronic Hepatitis C Virus: Part 1 of the DORA Study.

Jonas MM, Squires RH, Rhee SM, Lin CW, Bessho K, Feiterna-Sperling C, Hierro L, Kelly D, Ling SC, Strokova T, Del Valle-Segarra A, Lovell S, Liu W, Ng TI, Porcalla A, Gonzalez YS, Burroughs M, Sokal E.

Hepatology. 2020 Feb;71(2):456-462. doi: 10.1002/hep.30840. Epub 2019 Aug 13.

17.

Gallbladder leiomyoma treated by laparoscopic cholecystectomy in a dog.

Lovell S, Singh A, Zur Linden A, Hagen C, Cuq B.

J Am Vet Med Assoc. 2019 Jul 1;255(1):85-89. doi: 10.2460/javma.255.1.85.

PMID:
31194662
18.

Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity.

Punchi Hewage AND, Yao H, Nammalwar B, Gnanasekaran KK, Lovell S, Bunce RA, Eshelman K, Phaniraj SM, Lee MM, Peterson BR, Battaile KP, Reitz AB, Rivera M.

J Am Chem Soc. 2019 May 22;141(20):8171-8184. doi: 10.1021/jacs.9b00394. Epub 2019 May 9.

19.

Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection.

Molinaro AL, Kashipathy MM, Lovell S, Battaile KP, Coussens NP, Shen M, Daines DA.

J Bacteriol. 2019 May 22;201(12). pii: e00026-19. doi: 10.1128/JB.00026-19. Print 2019 Jun 15.

20.

Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease.

Galasiti Kankanamalage AC, Weerawarna PM, Rathnayake AD, Kim Y, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC.

Proteins. 2019 Jul;87(7):579-587. doi: 10.1002/prot.25682. Epub 2019 Apr 1.

PMID:
30883881
21.

Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors.

Chang KO, Kim Y, Lovell S, Rathnayake AD, Groutas WC.

Viruses. 2019 Feb 25;11(2). pii: E197. doi: 10.3390/v11020197. Review.

22.

Landscape and local site variables differentially influence pollinators and pollination services in urban agricultural sites.

Bennett AB, Lovell S.

PLoS One. 2019 Feb 13;14(2):e0212034. doi: 10.1371/journal.pone.0212034. eCollection 2019.

23.

Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors.

Jendroszek A, Madsen JB, Chana-Muñoz A, Dupont DM, Christensen A, Panitz F, Füchtbauer EM, Lovell SC, Jensen JK.

J Biol Chem. 2019 Mar 8;294(10):3794-3805. doi: 10.1074/jbc.RA118.005419. Epub 2019 Jan 16.

24.

Glecaprevir/pibrentasvir for the treatment of chronic hepatitis C virus infection.

Mensa FJ, Lovell S, Pilot-Matias T, Liu W.

Future Microbiol. 2019 Jan;14:89-110. doi: 10.2217/fmb-2018-0233. Epub 2018 Nov 30. Review.

PMID:
30499343
25.

Glecaprevir/Pibrentasvir in patients with chronic HCV genotype 3 infection: An integrated phase 2/3 analysis.

Flamm S, Mutimer D, Asatryan A, Wang S, Rockstroh J, Horsmans Y, Kwo PY, Weiland O, Villa E, Heo J, Gane E, Ryder SD, Welzel TM, Ruane PJ, Agarwal K, Ng TI, Xue Z, Lovell SS, Krishnan P, Kopecky-Bromberg S, Trinh R, Mensa FJ, Wyles DL.

J Viral Hepat. 2019 Mar;26(3):337-349. doi: 10.1111/jvh.13038. Epub 2018 Dec 11.

PMID:
30421537
26.

Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.

De Vita E, Schüler P, Lovell S, Lohbeck J, Kullmann S, Rabinovich E, Sananes A, Heßling B, Hamon V, Papo N, Hess J, Tate EW, Gunkel N, Miller AK.

J Med Chem. 2018 Oct 11;61(19):8859-8874. doi: 10.1021/acs.jmedchem.8b01106. Epub 2018 Sep 28.

PMID:
30212625
27.

Improved fragment-based protein structure prediction by redesign of search heuristics.

Kandathil SM, Garza-Fabre M, Handl J, Lovell SC.

Sci Rep. 2018 Sep 12;8(1):13694. doi: 10.1038/s41598-018-31891-8.

28.

Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site.

Wijerathne H, Yao H, Wang Y, Lovell S, Battaile KP, Rivera M.

Biochemistry. 2018 Sep 25;57(38):5533-5543. doi: 10.1021/acs.biochem.8b00823. Epub 2018 Sep 13.

29.

Resistance Analysis of a 3-Day Monotherapy Study with Glecaprevir or Pibrentasvir in Patients with Chronic Hepatitis C Virus Genotype 1 Infection.

Ng TI, Pilot-Matias T, Tripathi R, Schnell G, Krishnan P, Reisch T, Beyer J, Dekhtyar T, Irvin M, Lu L, Asatryan A, Campbell A, Yao B, Lovell S, Mensa F, Lawitz EJ, Kort J, Collins C.

Viruses. 2018 Aug 28;10(9). pii: E462. doi: 10.3390/v10090462.

30.

Erratum: EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.

Paredes R, Schneider M, Stevens A, White DJ, K Williamson AJ, Muter J, Pearson S, Kelly JR, Connors K, Wiseman DH, Chadwick JA, Löffler H, Teng HY, Lovell S, Unwin R, van de Vrugt HJ, Smith H, Kustikova O, Schambach A, P Somervaille TC, Pierce A, Whetton AD, Meyer S.

Nucleic Acids Res. 2018 Sep 19;46(16):8663. doi: 10.1093/nar/gky711. No abstract available.

31.

Efficacy and Pharmacokinetics of Glecaprevir and Pibrentasvir With Concurrent Use of Acid-Reducing Agents in Patients With Chronic HCV Infection.

Flamm S, Reddy KR, Zadeikis N, Hassanein T, Bacon BR, Maieron A, Zeuzem S, Bourliere M, Calleja JL, Kosloski MP, Oberoi RK, Lin CW, Yu Y, Lovell S, Semizarov D, Mensa FJ.

Clin Gastroenterol Hepatol. 2019 Feb;17(3):527-535.e6. doi: 10.1016/j.cgh.2018.07.003. Epub 2018 Sep 10.

32.

EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.

Paredes R, Schneider M, Stevens A, White DJ, Williamson AJK, Muter J, Pearson S, Kelly JR, Connors K, Wiseman DH, Chadwick JA, Löffler H, Teng HY, Lovell S, Unwin R, van de Vrugt HJ, Smith H, Kustikova O, Schambach A, Somervaille TCP, Pierce A, Whetton AD, Meyer S.

Nucleic Acids Res. 2018 Sep 6;46(15):7662-7674. doi: 10.1093/nar/gky536. Erratum in: Nucleic Acids Res. 2018 Sep 19;46(16):8663.

33.

Using disruptive insertional mutagenesis to identify the in situ structure-function landscape of the Shigella translocator protein IpaB.

Barta ML, Tachiyama S, Muthuramalingam M, Arizmendi O, Villanueva CE, Ramyar KX, Geisbrecht BV, Lovell S, Battaile KP, Picking WL, Picking WD.

Protein Sci. 2018 Aug;27(8):1392-1406. doi: 10.1002/pro.3428. Epub 2018 May 3.

34.

High SVR12 with 8-week and 12-week glecaprevir/pibrentasvir therapy: An integrated analysis of HCV genotype 1-6 patients without cirrhosis.

Puoti M, Foster GR, Wang S, Mutimer D, Gane E, Moreno C, Chang TT, Lee SS, Marinho R, Dufour JF, Pol S, Hezode C, Gordon SC, Strasser SI, Thuluvath PJ, Zhang Z, Lovell S, Pilot-Matias T, Mensa FJ.

J Hepatol. 2018 Aug;69(2):293-300. doi: 10.1016/j.jhep.2018.03.007. Epub 2018 Mar 16.

35.

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element.

Galasiti Kankanamalage AC, Kim Y, Damalanka VC, Rathnayake AD, Fehr AR, Mehzabeen N, Battaile KP, Lovell S, Lushington GH, Perlman S, Chang KO, Groutas WC.

Eur J Med Chem. 2018 Apr 25;150:334-346. doi: 10.1016/j.ejmech.2018.03.004. Epub 2018 Mar 6.

36.

Awareness and use of family planning methods among iTaukei women in Fiji and New Zealand.

Cammock R, Priest P, Lovell S, Herbison P.

Aust N Z J Public Health. 2018 Aug;42(4):365-371. doi: 10.1111/1753-6405.12761. Epub 2018 Jan 31.

PMID:
29384239
37.

Place, health, and community attachment: Is community capacity associated with self-rated health at the individual level?

Lovell SA, Gray AR, Boucher SE.

SSM Popul Health. 2016 Dec 7;3:153-161. doi: 10.1016/j.ssmph.2016.12.002. eCollection 2017 Dec.

38.

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.

Damalanka VC, Kim Y, Galasiti Kankanamalage AC, Rathnayake AD, Mehzabeen N, Battaile KP, Lovell S, Nguyen HN, Lushington GH, Chang KO, Groutas WC.

Eur J Med Chem. 2018 Jan 1;143:881-890. doi: 10.1016/j.ejmech.2017.12.014. Epub 2017 Dec 6.

39.

Frontiers in alley cropping: Transformative solutions for temperate agriculture.

Wolz KJ, Lovell ST, Branham BE, Eddy WC, Keeley K, Revord RS, Wander MM, Yang WH, DeLucia EH.

Glob Chang Biol. 2018 Mar;24(3):883-894. doi: 10.1111/gcb.13986. Epub 2017 Dec 8.

PMID:
29218801
40.

Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development.

Ridge LA, Mitchell K, Al-Anbaki A, Shaikh Qureshi WM, Stephen LA, Tenin G, Lu Y, Lupu IE, Clowes C, Robertson A, Barnes E, Wright JA, Keavney B, Ehler E, Lovell SC, Kadler KE, Hentges KE.

PLoS Genet. 2017 Oct 30;13(10):e1007068. doi: 10.1371/journal.pgen.1007068. eCollection 2017 Oct.

41.

MolProbity: More and better reference data for improved all-atom structure validation.

Williams CJ, Headd JJ, Moriarty NW, Prisant MG, Videau LL, Deis LN, Verma V, Keedy DA, Hintze BJ, Chen VB, Jain S, Lewis SM, Arendall WB 3rd, Snoeyink J, Adams PD, Lovell SC, Richardson JS, Richardson DC.

Protein Sci. 2018 Jan;27(1):293-315. doi: 10.1002/pro.3330. Epub 2017 Nov 27.

42.

Structural characterization of the Man5 glycoform of human IgG3 Fc.

Shah IS, Lovell S, Mehzabeen N, Battaile KP, Tolbert TJ.

Mol Immunol. 2017 Dec;92:28-37. doi: 10.1016/j.molimm.2017.10.001. Epub 2017 Oct 12.

43.

Family planning unmet need and access among iTaukei women in New Zealand and Fiji.

Cammock R, Herbison P, Lovell S, Priest P.

N Z Med J. 2017 Sep 22;130(1462):46-53.

PMID:
28934767
44.

Glecaprevir/pibrentasvir for hepatitis C virus genotype 3 patients with cirrhosis and/or prior treatment experience: A partially randomized phase 3 clinical trial.

Wyles D, Poordad F, Wang S, Alric L, Felizarta F, Kwo PY, Maliakkal B, Agarwal K, Hassanein T, Weilert F, Lee SS, Kort J, Lovell SS, Liu R, Lin CW, Pilot-Matias T, Krishnan P, Mensa FJ.

Hepatology. 2018 Feb;67(2):514-523. doi: 10.1002/hep.29541. Epub 2018 Jan 4.

45.

Adaptive HIV-1 evolutionary trajectories are constrained by protein stability.

Olabode AS, Kandathil SM, Lovell SC, Robertson DL.

Virus Evol. 2017 Aug 1;3(2):vex019. doi: 10.1093/ve/vex019. eCollection 2017 Jul.

46.

Single-domain antibodies pinpoint potential targets within Shigella invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion.

Barta ML, Shearer JP, Arizmendi O, Tremblay JM, Mehzabeen N, Zheng Q, Battaile KP, Lovell S, Tzipori S, Picking WD, Shoemaker CB, Picking WL.

J Biol Chem. 2017 Oct 6;292(40):16677-16687. doi: 10.1074/jbc.M117.802231. Epub 2017 Aug 25.

47.

Rapid functional and evolutionary changes follow gene duplication in yeast.

Naseeb S, Ames RM, Delneri D, Lovell SC.

Proc Biol Sci. 2017 Aug 30;284(1861). pii: 20171393. doi: 10.1098/rspb.2017.1393.

48.

Canine intrathoracic sarcoma with ultrastructural characteristics of human synovial sarcoma - case report.

Lovell S, Burchell RK, Roady PJ, Fredrickson RL, Gal A.

BMC Vet Res. 2017 Aug 16;13(1):247. doi: 10.1186/s12917-017-1181-6.

49.

Glecaprevir and pibrentasvir yield high response rates in patients with HCV genotype 1-6 without cirrhosis.

Kwo PY, Poordad F, Asatryan A, Wang S, Wyles DL, Hassanein T, Felizarta F, Sulkowski MS, Gane E, Maliakkal B, Overcash JS, Gordon SC, Muir AJ, Aguilar H, Agarwal K, Dore GJ, Lin CW, Liu R, Lovell SS, Ng TI, Kort J, Mensa FJ.

J Hepatol. 2017 Aug;67(2):263-271. doi: 10.1016/j.jhep.2017.03.039. Epub 2017 Apr 13.

PMID:
28412293
50.

Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.

Yu H, Dranchak P, Li Z, MacArthur R, Munson MS, Mehzabeen N, Baird NJ, Battalie KP, Ross D, Lovell S, Carlow CK, Suga H, Inglese J.

Nat Commun. 2017 Apr 3;8:14932. doi: 10.1038/ncomms14932.

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