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Items: 1 to 50 of 114


The Nature and Severity of Workplace Injuries in Construction: Engendering Operational Benchmarking.

Love PED, Teo P, Smith J, Ackermann F, Zhou Y.

Ergonomics. 2019 Jul 15:1-32. doi: 10.1080/00140139.2019.1644379. [Epub ahead of print]


Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification.

Magli A, Baik J, Pota P, Cordero CO, Kwak IY, Garry DJ, Love PE, Dynlacht BD, Perlingeiro RCR.

Nat Commun. 2019 May 24;10(1):2316. doi: 10.1038/s41467-019-10318-6.


Regulatory mechanisms in T cell receptor signalling.

Gaud G, Lesourne R, Love PE.

Nat Rev Immunol. 2018 Aug;18(8):485-497. doi: 10.1038/s41577-018-0020-8. Review.


Putting into practice error management theory: Unlearning and learning to manage action errors in construction.

Love PED, Smith J, Teo P.

Appl Ergon. 2018 May;69:104-111. doi: 10.1016/j.apergo.2018.01.007. Epub 2018 Feb 1.


THEMIS: Two Models, Different Thresholds.

Choi S, Cornall R, Lesourne R, Love PE.

Trends Immunol. 2017 Sep;38(9):622-632. doi: 10.1016/ Epub 2017 Jul 8. Review.


Erratum: THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.

Choi S, Warzecha C, Zvezdova E, Lee J, Argenty J, Lesourne R, Aravind L, Love PE.

Nat Immunol. 2017 May 18;18(6):705. doi: 10.1038/ni0617-705c. No abstract available.


THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.

Choi S, Warzecha C, Zvezdova E, Lee J, Argenty J, Lesourne R, Aravind L, Love PE.

Nat Immunol. 2017 Apr;18(4):433-441. doi: 10.1038/ni.3692. Epub 2017 Feb 27. Erratum in: Nat Immunol. 2017 May 18;18(6):705.


Chromosome choice for initiation of V-(D)-J recombination is not governed by genomic imprinting.

Gebert C, Correia L, Li Z, Petrie HT, Love PE, Pfeifer K.

Immunol Cell Biol. 2017 May;95(5):473-477. doi: 10.1038/icb.2017.1. Epub 2017 Feb 28.


Themis2 lowers the threshold for B cell activation during positive selection.

Cheng D, Deobagkar-Lele M, Zvezdova E, Choi S, Uehara S, Baup D, Bennett SC, Bull KR, Crockford TL, Ferry H, Warzecha C, Marcellin M, de Peredo AG, Lesourne R, Anzilotti C, Love PE, Cornall RJ.

Nat Immunol. 2017 Feb;18(2):205-213. doi: 10.1038/ni.3642. Epub 2016 Dec 19.


Systems thinking in workplace safety and health in construction: Bridging the gap between theory and practice.

Love PED, Ding L, Luo H.

Accid Anal Prev. 2016 Aug;93:227-229. doi: 10.1016/j.aap.2016.05.026. No abstract available.


CD5-mediated inhibition of TCR signaling proceeds normally in the absence of SHP-1.

Dong B, Somani AK, Love PE, Zheng X, Chen X, Zhang J.

Int J Mol Med. 2016 Jul;38(1):45-56. doi: 10.3892/ijmm.2016.2592. Epub 2016 May 17.


Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability.

Zvezdova E, Mikolajczak J, Garreau A, Marcellin M, Rigal L, Lee J, Choi S, Blaize G, Argenty J, Familiades J, Li L, Gonzalez de Peredo A, Burlet-Schiltz O, Love PE, Lesourne R.

Sci Signal. 2016 May 17;9(428):ra51. doi: 10.1126/scisignal.aad1576.


Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.

Triplett TA, Cardenas KT, Lancaster JN, Hu Z, Selden HJ, Jasso GJ, Balasubramanyam S, Chan K, Li L, Chen X, Marcogliese AN, Davé UP, Love PE, Ehrlich LI.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1016-25. doi: 10.1073/pnas.1520245113. Epub 2016 Feb 9.


A case study of machinery maintenance protocols and procedures within the UK utilities sector.

Edwards DJ, Love PED.

Accid Anal Prev. 2016 Aug;93:319-329. doi: 10.1016/j.aap.2015.10.031. Epub 2015 Nov 4.


Assessment of T Cell Development by Flow Cytometry.

Lee JY, Love PE.

Methods Mol Biol. 2016;1323:47-64. doi: 10.1007/978-1-4939-2809-5_4.


LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.

Choi YS, Gullicksrud JA, Xing S, Zeng Z, Shan Q, Li F, Love PE, Peng W, Xue HH, Crotty S.

Nat Immunol. 2015 Sep;16(9):980-90. doi: 10.1038/ni.3226. Epub 2015 Jul 27.


TCR ITAM multiplicity is required for the generation of follicular helper T-cells.

Hwang S, Palin AC, Li L, Song KD, Lee J, Herz J, Tubo N, Chu H, Pepper M, Lesourne R, Zvezdova E, Pinkhasov J, Jenkins MK, McGavern D, Love PE.

Nat Commun. 2015 May 11;6:6982. doi: 10.1038/ncomms7982.


Sociotechnical attributes of safe and unsafe work systems.

Kleiner BM, Hettinger LJ, DeJoy DM, Huang YH, Love PE.

Ergonomics. 2015;58(4):635-49. doi: 10.1080/00140139.2015.1009175.


CD5 helps aspiring regulatory T cells ward off unwelcome cytokine advances.

Palin AC, Love PE.

Immunity. 2015 Mar 17;42(3):395-6. doi: 10.1016/j.immuni.2015.02.018.


Abrogation of CC chemokine receptor 9 ameliorates collagen-induced arthritis of mice.

Yokoyama W, Kohsaka H, Kaneko K, Walters M, Takayasu A, Fukuda S, Miyabe C, Miyabe Y, Love PE, Nakamoto N, Kanai T, Watanabe-Imai K, Charvat TT, Penfold ME, Jaen J, Schall TJ, Harigai M, Miyasaka N, Nanki T.

Arthritis Res Ther. 2014 Sep 24;16(5):445. doi: 10.1186/s13075-014-0445-9.


A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.

Vacchio MS, Wang L, Bouladoux N, Carpenter AC, Xiong Y, Williams LC, Wohlfert E, Song KD, Belkaid Y, Love PE, Bosselut R.

Nat Immunol. 2014 Oct;15(10):947-56. doi: 10.1038/ni.2960. Epub 2014 Aug 17.


In vivo functional mapping of the conserved protein domains within murine Themis1.

Zvezdova E, Lee J, El-Khoury D, Barr V, Akpan I, Samelson L, Love PE.

Immunol Cell Biol. 2014 Sep;92(8):721-8. doi: 10.1038/icb.2014.43. Epub 2014 Jun 17.


Ldb1 complexes: the new master regulators of erythroid gene transcription.

Love PE, Warzecha C, Li L.

Trends Genet. 2014 Jan;30(1):1-9. doi: 10.1016/j.tig.2013.10.001. Epub 2013 Nov 27. Review.


Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation.

Li L, Freudenberg J, Cui K, Dale R, Song SH, Dean A, Zhao K, Jothi R, Love PE.

Blood. 2013 May 30;121(22):4575-85. doi: 10.1182/blood-2013-01-479451. Epub 2013 Apr 22.


Thpok-independent repression of Runx3 by Gata3 during CD4+ T-cell differentiation in the thymus.

Xiong Y, Castro E, Yagi R, Zhu J, Lesourne R, Love PE, Feigenbaum L, Bosselut R.

Eur J Immunol. 2013 Apr;43(4):918-28. doi: 10.1002/eji.201242944. Epub 2013 Feb 12.


Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease.

Hwang S, Song KD, Lesourne R, Lee J, Pinkhasov J, Li L, El-Khoury D, Love PE.

J Exp Med. 2012 Sep 24;209(10):1781-95. Epub 2012 Sep 3.


Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.

Lesourne R, Zvezdova E, Song KD, El-Khoury D, Uehara S, Barr VA, Samelson LE, Love PE.

J Immunol. 2012 Aug 1;189(3):1154-61. doi: 10.4049/jimmunol.1200123. Epub 2012 Jun 25.


Dynamics of safety performance and culture: a group model building approach.

Goh YM, Love PE, Stagbouer G, Annesley C.

Accid Anal Prev. 2012 Sep;48:118-25. doi: 10.1016/j.aap.2011.05.010. Epub 2011 Jul 2.


Error begat error: design error analysis and prevention in social infrastructure projects.

Love PE, Lopez R, Edwards DJ, Goh YM.

Accid Anal Prev. 2012 Sep;48:100-10. doi: 10.1016/j.aap.2011.02.027. Epub 2011 Mar 27.


Editorial. Construction and engineering projects.

Love PE, Goh YM, Smallwood J.

Accid Anal Prev. 2012 Sep;48:97-9. doi: 10.1016/j.aap.2011.07.002. Epub 2011 Jul 30. No abstract available.


Deconstructing Ras signaling in the thymus.

Kortum RL, Sommers CL, Pinski JM, Alexander CP, Merrill RK, Li W, Love PE, Samelson LE.

Mol Cell Biol. 2012 Jul;32(14):2748-59. doi: 10.1128/MCB.00317-12. Epub 2012 May 14.


CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.

Nakamoto N, Ebinuma H, Kanai T, Chu PS, Ono Y, Mikami Y, Ojiro K, Lipp M, Love PE, Saito H, Hibi T.

Gastroenterology. 2012 Feb;142(2):366-76. doi: 10.1053/j.gastro.2011.10.039. Epub 2011 Nov 10.


Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice.

Cassani B, Villablanca EJ, Quintana FJ, Love PE, Lacy-Hulbert A, Blaner WS, Sparwasser T, Snapper SB, Weiner HL, Mora JR.

Gastroenterology. 2011 Dec;141(6):2109-18. doi: 10.1053/j.gastro.2011.09.015. Epub 2011 Sep 16.


Targeted Sos1 deletion reveals its critical role in early T-cell development.

Kortum RL, Sommers CL, Alexander CP, Pinski JM, Li W, Grinberg A, Lee J, Love PE, Samelson LE.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12407-12. doi: 10.1073/pnas.1104295108. Epub 2011 Jul 11.


Signal integration and crosstalk during thymocyte migration and emigration.

Love PE, Bhandoola A.

Nat Rev Immunol. 2011 Jun 24;11(7):469-77. doi: 10.1038/nri2989. Review.


Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells.

Li L, Jothi R, Cui K, Lee JY, Cohen T, Gorivodsky M, Tzchori I, Zhao Y, Hayes SM, Bresnick EH, Zhao K, Westphal H, Love PE.

Nat Immunol. 2011 Feb;12(2):129-36. doi: 10.1038/ni.1978. Epub 2010 Dec 26.


A requirement for Lim domain binding protein 1 in erythropoiesis.

Li L, Lee JY, Gross J, Song SH, Dean A, Love PE.

J Exp Med. 2010 Nov 22;207(12):2543-50. doi: 10.1084/jem.20100504. Epub 2010 Nov 1.


ITAM-mediated signaling by the T-cell antigen receptor.

Love PE, Hayes SM.

Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a002485. doi: 10.1101/cshperspect.a002485. Epub 2010 Apr 28. Review.


Beyond alphabeta/gammadelta lineage commitment: TCR signal strength regulates gammadelta T cell maturation and effector fate.

Hayes SM, Laird RM, Love PE.

Semin Immunol. 2010 Aug;22(4):247-51. doi: 10.1016/j.smim.2010.04.006. Epub 2010 May 8. Review.


Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine.

Wang C, Kang SG, HogenEsch H, Love PE, Kim CH.

J Immunol. 2010 May 15;184(10):5519-26. doi: 10.4049/jimmunol.0903942. Epub 2010 Apr 16.


CCR6 is required for IL-23-induced psoriasis-like inflammation in mice.

Hedrick MN, Lonsdorf AS, Shirakawa AK, Richard Lee CC, Liao F, Singh SP, Zhang HH, Grinberg A, Love PE, Hwang ST, Farber JM.

J Clin Invest. 2009 Aug;119(8):2317-29.


Themis, a T cell-specific protein important for late thymocyte development.

Lesourne R, Uehara S, Lee J, Song KD, Li L, Pinkhasov J, Zhang Y, Weng NP, Wildt KF, Wang L, Bosselut R, Love PE.

Nat Immunol. 2009 Aug;10(8):840-7. doi: 10.1038/ni.1768. Epub 2009 Jul 13. Erratum in: Nat Immunol. 2010 Jan;11(1):97.


The cytoplasmic tail of the T cell receptor CD3 epsilon subunit contains a phospholipid-binding motif that regulates T cell functions.

Deford-Watts LM, Tassin TC, Becker AM, Medeiros JJ, Albanesi JP, Love PE, Wülfing C, van Oers NS.

J Immunol. 2009 Jul 15;183(2):1055-64. doi: 10.4049/jimmunol.0900404. Epub 2009 Jun 19.


LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth.

Tzchori I, Day TF, Carolan PJ, Zhao Y, Wassif CA, Li L, Lewandoski M, Gorivodsky M, Love PE, Porter FD, Westphal H, Yang Y.

Development. 2009 Apr;136(8):1375-85. doi: 10.1242/dev.026476.


Bam32: a novel mediator of Erk activation in T cells.

Sommers CL, Gurson JM, Surana R, Barda-Saad M, Lee J, Kishor A, Li W, Gasser AJ, Barr VA, Miyaji M, Love PE, Samelson LE.

Int Immunol. 2008 Jul;20(7):811-8. doi: 10.1093/intimm/dxn039. Epub 2008 Apr 29.


Tyrosine phosphorylation controls nuclear localization and transcriptional activity of Ssdp1 in mammalian cells.

Dey-Guha I, Malik N, Lesourne R, Love PE, Westphal H.

J Cell Biochem. 2008 Apr 15;103(6):1856-65.


A retrospective on the requirements for gammadelta T-cell development.

Hayes SM, Love PE.

Immunol Rev. 2007 Feb;215:8-14. Review.


Selective thymus settling regulated by cytokine and chemokine receptors.

Schwarz BA, Sambandam A, Maillard I, Harman BC, Love PE, Bhandoola A.

J Immunol. 2007 Feb 15;178(4):2008-17.


Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.

Erman B, Alag AS, Dahle O, van Laethem F, Sarafova SD, Guinter TI, Sharrow SO, Grinberg A, Love PE, Singer A.

J Immunol. 2006 Nov 15;177(10):6613-25.

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