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Items: 1 to 50 of 129

1.

The Infant Injury Database: A Tool for the Study of Injury Patterns in Medicolegal Investigations of Child Abuse.

Soto Martinez ME, Love JC, Pinto DC, Wiersema JM, Derrick SM, Bachim A, Greeley C, Donaruma-Kwoh M, Truong VTT, Gao S, Crowder CM.

J Forensic Sci. 2019 Jul 2. doi: 10.1111/1556-4029.14120. [Epub ahead of print]

PMID:
31265140
2.

A combined screening and in silico strategy for the rapid design of integrated downstream processes for process and product-related impurity removal.

Vecchiarello N, Timmick SM, Goodwine C, Crowell LE, Love KR, Love JC, Cramer SM.

Biotechnol Bioeng. 2019 Sep;116(9):2178-2190. doi: 10.1002/bit.27018. Epub 2019 Jun 29.

PMID:
31081177
3.

Sharp force trauma analysis in bone and cartilage: A literature review.

Love JC.

Forensic Sci Int. 2019 Jun;299:119-127. doi: 10.1016/j.forsciint.2019.03.035. Epub 2019 Mar 26. Review.

PMID:
30991210
4.

Challenging the workhorse: Comparative analysis of eukaryotic micro-organisms for expressing monoclonal antibodies.

Jiang H, Horwitz AA, Wright C, Tai A, Znameroski EA, Tsegaye Y, Warbington H, Bower BS, Alves C, Co C, Jonnalagadda K, Platt D, Walter JM, Natarajan V, Ubersax JA, Cherry JR, Love JC.

Biotechnol Bioeng. 2019 Jun;116(6):1449-1462. doi: 10.1002/bit.26951. Epub 2019 Mar 7.

PMID:
30739333
5.

Cell and fluid sampling microneedle patches for monitoring skin-resident immunity.

Mandal A, Boopathy AV, Lam LKW, Moynihan KD, Welch ME, Bennett NR, Turvey ME, Thai N, Van JH, Love JC, Hammond PT, Irvine DJ.

Sci Transl Med. 2018 Nov 14;10(467). pii: eaar2227. doi: 10.1126/scitranslmed.aar2227.

PMID:
30429353
6.

Tumor fraction in cell-free DNA as a biomarker in prostate cancer.

Choudhury AD, Werner L, Francini E, Wei XX, Ha G, Freeman SS, Rhoades J, Reed SC, Gydush G, Rotem D, Lo C, Taplin ME, Harshman LC, Zhang Z, O'Connor EP, Stover DG, Parsons HA, Getz G, Meyerson M, Love JC, Hahn WC, Adalsteinsson VA.

JCI Insight. 2018 Nov 2;3(21). pii: 122109. doi: 10.1172/jci.insight.122109.

7.

Intentional Fracture of Bioprosthetic Valve Frames in Patients Undergoing Valve-in-Valve Transcatheter Pulmonary Valve Replacement.

Shahanavaz S, Asnes JD, Grohmann J, Qureshi AM, Rome JJ, Tanase D, Crystal MA, Latson LA, Morray BH, Hellenbrand W, Balzer DT, Gewillig M, Love JC, Berdjis F, Gillespie MJ, McElhinney DB.

Circ Cardiovasc Interv. 2018 Aug;11(8):e006453. doi: 10.1161/CIRCINTERVENTIONS.118.006453.

PMID:
30354783
8.

On-demand manufacturing of clinical-quality biopharmaceuticals.

Crowell LE, Lu AE, Love KR, Stockdale A, Timmick SM, Wu D, Wang YA, Doherty W, Bonnyman A, Vecchiarello N, Goodwine C, Bradbury L, Brady JR, Clark JJ, Colant NA, Cvetkovic A, Dalvie NC, Liu D, Liu Y, Mascarenhas CA, Matthews CB, Mozdzierz NJ, Shah KA, Wu SL, Hancock WS, Braatz RD, Cramer SM, Love JC.

Nat Biotechnol. 2018 Oct 1. doi: 10.1038/nbt.4262. [Epub ahead of print]

9.

Two Vaccines for Staphylococcus aureus Induce a B-Cell-Mediated Immune Response.

Dupont CD, Scully IL, Zimnisky RM, Monian B, Rossitto CP, O'Connell EB, Jansen KU, Anderson AS, Love JC.

mSphere. 2018 Aug 22;3(4). pii: e00217-18. doi: 10.1128/mSphere.00217-18.

10.

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing.

Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D; PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M.

Cell. 2018 Jul 12;174(2):433-447.e19. doi: 10.1016/j.cell.2018.05.036. Epub 2018 Jun 18.

11.

Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma.

Manier S, Park J, Capelletti M, Bustoros M, Freeman SS, Ha G, Rhoades J, Liu CJ, Huynh D, Reed SC, Gydush G, Salem KZ, Rotem D, Freymond C, Yosef A, Perilla-Glen A, Garderet L, Van Allen EM, Kumar S, Love JC, Getz G, Adalsteinsson VA, Ghobrial IM.

Nat Commun. 2018 Apr 27;9(1):1691. doi: 10.1038/s41467-018-04001-5.

12.

An impurity characterization based approach for the rapid development of integrated downstream purification processes.

Timmick SM, Vecchiarello N, Goodwine C, Crowell LE, Love KR, Love JC, Cramer SM.

Biotechnol Bioeng. 2018 Aug;115(8):2048-2060. doi: 10.1002/bit.26718. Epub 2018 May 4.

PMID:
29679482
13.

Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.

Stover DG, Parsons HA, Ha G, Freeman SS, Barry WT, Guo H, Choudhury AD, Gydush G, Reed SC, Rhoades J, Rotem D, Hughes ME, Dillon DA, Partridge AH, Wagle N, Krop IE, Getz G, Golub TR, Love JC, Winer EP, Tolaney SM, Lin NU, Adalsteinsson VA.

J Clin Oncol. 2018 Feb 20;36(6):543-553. doi: 10.1200/JCO.2017.76.0033. Epub 2018 Jan 3.

14.

The yeast stands alone: the future of protein biologic production.

Love KR, Dalvie NC, Love JC.

Curr Opin Biotechnol. 2018 Oct;53:50-58. doi: 10.1016/j.copbio.2017.12.010. Epub 2017 Dec 22. Review.

PMID:
29277062
15.

Erythrocyte efferocytosis modulates macrophages towards recovery after intracerebral hemorrhage.

Chang CF, Goods BA, Askenase MH, Hammond MD, Renfroe SC, Steinschneider AF, Landreneau MJ, Ai Y, Beatty HE, da Costa LHA, Mack M, Sheth KN, Greer DM, Huttner A, Coman D, Hyder F, Ghosh S, Rothlin CV, Love JC, Sansing LH.

J Clin Invest. 2018 Feb 1;128(2):607-624. doi: 10.1172/JCI95612. Epub 2017 Dec 18.

16.

Cover Image, Volume 115, Number 1, January 2018.

Matthews CB, Kuo A, Love KR, Love JC.

Biotechnol Bioeng. 2018 Jan;115(1):i. doi: 10.1002/bit.26409.

PMID:
29165792
17.

Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.

Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV 2nd, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL.

Stem Cell Reports. 2017 Dec 12;9(6):1868-1884. doi: 10.1016/j.stemcr.2017.10.015. Epub 2017 Nov 16.

18.

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ, Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC, Tolaney SM, Van Allen EM, Winer EP, Lin NU, Nakabayashi M, Taplin ME, Johannessen CM, Garraway LA, Golub TR, Boehm JS, Wagle N, Getz G, Love JC, Meyerson M.

Nat Commun. 2017 Nov 6;8(1):1324. doi: 10.1038/s41467-017-00965-y.

19.

Integrated Bottom-Up and Top-Down Liquid Chromatography-Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products.

Wang YA, Wu D, Auclair JR, Salisbury JP, Sarin R, Tang Y, Mozdzierz NJ, Shah K, Zhang AF, Wu SL, Agar JN, Love JC, Love KR, Hancock WS.

Anal Chem. 2017 Dec 5;89(23):12771-12777. doi: 10.1021/acs.analchem.7b03026. Epub 2017 Nov 21.

PMID:
29096433
20.

Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires.

Jia B, McNeil LK, Dupont CD, Tsioris K, Barry RM, Scully IL, Ogunniyi AO, Gonzalez C, Pride MW, Gierahn TM, Liberator PA, Jansen KU, Love JC.

PLoS One. 2017 Sep 14;12(9):e0183738. doi: 10.1371/journal.pone.0183738. eCollection 2017.

21.

Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme.

Goods BA, Hernandez AL, Lowther DE, Lucca LE, Lerner BA, Gunel M, Raddassi K, Coric V, Hafler DA, Love JC.

PLoS One. 2017 Sep 7;12(9):e0181538. doi: 10.1371/journal.pone.0181538. eCollection 2017.

22.

Development of a general defined medium for Pichia pastoris.

Matthews CB, Kuo A, Love KR, Love JC.

Biotechnol Bioeng. 2018 Jan;115(1):103-113. doi: 10.1002/bit.26440. Epub 2017 Oct 6.

PMID:
28865117
23.

Opportunities and challenges of real-time release testing in biopharmaceutical manufacturing.

Jiang M, Severson KA, Love JC, Madden H, Swann P, Zang L, Braatz RD.

Biotechnol Bioeng. 2017 Nov;114(11):2445-2456. doi: 10.1002/bit.26383. Epub 2017 Aug 29. Review.

PMID:
28710854
24.

Reexamining opportunities for therapeutic protein production in eukaryotic microorganisms.

Matthews CB, Wright C, Kuo A, Colant N, Westoby M, Love JC.

Biotechnol Bioeng. 2017 Nov;114(11):2432-2444. doi: 10.1002/bit.26378. Epub 2017 Aug 17. Review.

PMID:
28688187
25.

A method for learning a sparse classifier in the presence of missing data for high-dimensional biological datasets.

Severson KA, Monian B, Love JC, Braatz RD.

Bioinformatics. 2017 Sep 15;33(18):2897-2905. doi: 10.1093/bioinformatics/btx224.

PMID:
28431087
26.

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.

Gierahn TM, Wadsworth MH 2nd, Hughes TK, Bryson BD, Butler A, Satija R, Fortune S, Love JC, Shalek AK.

Nat Methods. 2017 Apr;14(4):395-398. doi: 10.1038/nmeth.4179. Epub 2017 Feb 13.

27.

Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects.

Huang Y, Ferrari G, Alter G, Forthal DN, Kappes JC, Lewis GK, Love JC, Borate B, Harris L, Greene K, Gao H, Phan TB, Landucci G, Goods BA, Dowell KG, Cheng HD, Bailey-Kellogg C, Montefiori DC, Ackerman ME.

J Immunol. 2016 Dec 15;197(12):4603-4612. Epub 2016 Nov 9.

28.

TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.

Taylor RA, Chang CF, Goods BA, Hammond MD, Mac Grory B, Ai Y, Steinschneider AF, Renfroe SC, Askenase MH, McCullough LD, Kasner SE, Mullen MT, Hafler DA, Love JC, Sansing LH.

J Clin Invest. 2017 Jan 3;127(1):280-292. doi: 10.1172/JCI88647. Epub 2016 Nov 28.

29.

Single-cell analysis at the threshold.

Chen X, Love JC, Navin NE, Pachter L, Stubbington MJ, Svensson V, Sweedler JV, Teichmann SA.

Nat Biotechnol. 2016 Nov 8;34(11):1111-1118. doi: 10.1038/nbt.3721. No abstract available.

PMID:
27824834
30.

Erratum to: Comparative genomics and transcriptomics of Pichia pastoris.

Love KR, Shah KA, Whittaker CA, Wu J, Bartlett MC, Ma D, Leeson RL, Priest M, Borowsky J, Young SK, Love JC.

BMC Genomics. 2016 Sep 28;17(1):762. No abstract available.

31.

A Size-Selective Intracellular Delivery Platform.

Saung MT, Sharei A, Adalsteinsson VA, Cho N, Kamath T, Ruiz C, Kirkpatrick J, Patel N, Mino-Kenudson M, Thayer SP, Langer R, Jensen KF, Liss AS, Love JC.

Small. 2016 Nov;12(42):5873-5881. doi: 10.1002/smll.201601155. Epub 2016 Sep 4.

32.

The Value of Anthropology in Medicolegal Death Investigation of Pediatric Nonaccidental Injury.

Love JC.

Acad Forensic Pathol. 2016 Sep;6(3):478-485. doi: 10.23907/2016.048. Epub 2016 Sep 1. Review.

33.

Skeletal Trauma: An Anthropological Review.

Love JC, Wiersema JM.

Acad Forensic Pathol. 2016 Sep;6(3):463-477. doi: 10.23907/2016.047. Epub 2016 Sep 1. Review.

34.

The Utility of Forensic Anthropology in the Medical Examiner's Office.

Crowder CM, Wiersema JM, Adams BJ, Austin DE, Love JC.

Acad Forensic Pathol. 2016 Sep;6(3):349-360. doi: 10.23907/2016.037. Epub 2016 Sep 1. Review.

35.

Comparative genomics and transcriptomics of Pichia pastoris.

Love KR, Shah KA, Whittaker CA, Wu J, Bartlett MC, Ma D, Leeson RL, Priest M, Borowsky J, Young SK, Love JC.

BMC Genomics. 2016 Aug 5;17:550. doi: 10.1186/s12864-016-2876-y. Erratum in: BMC Genomics. 2016 Sep 28;17(1):762.

36.

Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.

Donius LR, Cheng Y, Choi J, Sun ZY, Hanson M, Zhang M, Gierahn TM, Marquez S, Uduman M, Kleinstein SH, Irvine D, Love JC, Reinherz EL, Kim M.

J Virol. 2016 Sep 12;90(19):8875-90. doi: 10.1128/JVI.01089-16. Print 2016 Oct 1.

37.

PD-1 marks dysfunctional regulatory T cells in malignant gliomas.

Lowther DE, Goods BA, Lucca LE, Lerner BA, Raddassi K, van Dijk D, Hernandez AL, Duan X, Gunel M, Coric V, Krishnaswamy S, Love JC, Hafler DA.

JCI Insight. 2016 Apr 21;1(5). pii: e85935.

38.

Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes.

Liao MC, Muratore CR, Gierahn TM, Sullivan SE, Srikanth P, De Jager PL, Love JC, Young-Pearse TL.

J Neurosci. 2016 Feb 3;36(5):1730-46. doi: 10.1523/JNEUROSCI.2735-15.2016.

39.

Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing.

Tsioris K, Gupta NT, Ogunniyi AO, Zimnisky RM, Qian F, Yao Y, Wang X, Stern JN, Chari R, Briggs AW, Clouser CR, Vigneault F, Church GM, Garcia MN, Murray KO, Montgomery RR, Kleinstein SH, Love JC.

Integr Biol (Camb). 2015 Dec;7(12):1587-97. doi: 10.1039/c5ib00169b. Epub 2015 Oct 20.

40.

A Novel Method for Removing a Spinal Cord with Attached Cervical Ganglia from a Pediatric Decedent.

Peterson JE, Love JC, Pinto DC, Wolf DA, Sandberg G.

J Forensic Sci. 2016 Jan;61(1):241-4. doi: 10.1111/1556-4029.12925. Epub 2015 Aug 21.

PMID:
26296423
41.

The value and availability of forensic anthropological consultation in medicolegal death investigations.

Christensen AM, Passalacqua NV, Schmunk GA, Fudenberg J, Hartnett K, Mitchell RA Jr, Love JC, deJong J, Petaros A.

Forensic Sci Med Pathol. 2015 Sep;11(3):438-41. doi: 10.1007/s12024-015-9687-3. Epub 2015 Jul 1. No abstract available.

PMID:
26130173
42.

Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning.

Ozkumur AY, Goods BA, Love JC.

Small. 2015 Sep;11(36):4643-50. doi: 10.1002/smll.201500674. Epub 2015 Jun 29.

43.

A perfusion-capable microfluidic bioreactor for assessing microbial heterologous protein production.

Mozdzierz NJ, Love KR, Lee KS, Lee HL, Shah KA, Ram RJ, Love JC.

Lab Chip. 2015 Jul 21;15(14):2918-22. doi: 10.1039/c5lc00443h.

44.

Automated pipeline for rapid production and screening of HIV-specific monoclonal antibodies using pichia pastoris.

Shah KA, Clark JJ, Goods BA, Politano TJ, Mozdzierz NJ, Zimnisky RM, Leeson RL, Love JC, Love KR.

Biotechnol Bioeng. 2015 Dec;112(12):2624-9. doi: 10.1002/bit.25663. Epub 2015 Jul 31.

45.

Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects.

Patil SU, Ogunniyi AO, Calatroni A, Tadigotla VR, Ruiter B, Ma A, Moon J, Love JC, Shreffler WG.

J Allergy Clin Immunol. 2015 Jul;136(1):125-134.e12. doi: 10.1016/j.jaci.2015.03.026. Epub 2015 May 16.

46.

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis.

Cao Y, Goods BA, Raddassi K, Nepom GT, Kwok WW, Love JC, Hafler DA.

Sci Transl Med. 2015 May 13;7(287):287ra74. doi: 10.1126/scitranslmed.aaa8038.

47.

Calibrating genomic and allelic coverage bias in single-cell sequencing.

Zhang CZ, Adalsteinsson VA, Francis J, Cornils H, Jung J, Maire C, Ligon KL, Meyerson M, Love JC.

Nat Commun. 2015 Apr 16;6:6822. doi: 10.1038/ncomms7822.

48.

Microscopic saw mark analysis: an empirical approach.

Love JC, Derrick SM, Wiersema JM, Peters C.

J Forensic Sci. 2015 Jan;60 Suppl 1:S21-6. doi: 10.1111/1556-4029.12650. Epub 2014 Nov 14. Erratum in: J Forensic Sci. 2015 Jul;60(4):1113.

PMID:
25399533
49.

A proposed scheme for classifying pediatric rib head fractures using case examples.

Pinto DC, Love JC, Derrick SM, Wiersema JM, Donaruma-Kwoh M, Greeley CS.

J Forensic Sci. 2015 Jan;60(1):112-7. doi: 10.1111/1556-4029.12590. Epub 2014 Nov 12.

PMID:
25388901
50.

Nanowell-based immunoassays for measuring single-cell secretion: characterization of transport and surface binding.

Torres AJ, Hill AS, Love JC.

Anal Chem. 2014 Dec 2;86(23):11562-9. doi: 10.1021/ac4030297. Epub 2014 Nov 17.

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