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Different Patterns of Ecological Divergence Between Two Tetraploids and Their Diploid Counterpart in a Parapatric Linear Coastal Distribution Polyploid Complex.

Castro M, Loureiro J, Figueiredo A, Serrano M, Husband BC, Castro S.

Front Plant Sci. 2020 Mar 19;11:315. doi: 10.3389/fpls.2020.00315. eCollection 2020.


Hypoxia and Macrophages Act in Concert Towards a Beneficial Outcome in Colon Cancer.

Martins F, Oliveira R, Cavadas B, Pinto F, Cardoso AP, Castro F, Sousa B, Pinto ML, Silva AJ, Adão D, Loureiro JP, Pedro N, Reis RM, Pereira L, Oliveira MJ, Costa AM.

Cancers (Basel). 2020 Mar 28;12(4). pii: E818. doi: 10.3390/cancers12040818.


Correction to: Assessing genotype-phenotype associations in three dorsal colour morphs in the meadow spittlebug Philaenus spumarius (L.) (Hemiptera: Aphrophoridae) using genomic and transcriptomic resources.

Rodrigues ASB, Silva SE, Pina-Martins F, Loureiro J, Castro M, Gharbi K, Johnson KP, Dietrich CH, Borges PAV, Quartau JA, Jiggins CD, Paulo OS, Seabra SG.

BMC Genet. 2020 Mar 24;21(1):36. doi: 10.1186/s12863-020-00842-6.


Is selfing a reproductive assurance promoting polyploid establishment? Reduced fitness, leaky self-incompatibility and lower inbreeding depression in neotetraploids.

Siopa C, Dias MC, Castro M, Loureiro J, Castro S.

Am J Bot. 2020 Mar;107(3):526-538. doi: 10.1002/ajb2.1441. Epub 2020 Mar 6.


Modulation of amygdala reactivity following rapidly acting interventions for major depression.

Loureiro JRA, Leaver A, Vasavada M, Sahib AK, Kubicki A, Joshi S, Woods RP, Wade B, Congdon E, Espinoza R, Narr KL.

Hum Brain Mapp. 2020 May;41(7):1699-1710. doi: 10.1002/hbm.24895. Epub 2020 Mar 1.


Single and repeated ketamine treatment induces perfusion changes in sensory and limbic networks in major depressive disorder.

Sahib AK, Loureiro JRA, Vasavada MM, Kubicki A, Joshi SH, Wang K, Woods RP, Congdon E, Wang DJJ, Boucher ML, Espinoza R, Narr KL.

Eur Neuropsychopharmacol. 2020 Feb 12. pii: S0924-977X(20)30042-0. doi: 10.1016/j.euroneuro.2020.01.017. [Epub ahead of print]


Immuno-nanocarriers for brain delivery: limitations from in vitro to preclinical and clinical studies.

Loureiro JA, Ramalho MJ, Carmo Pereira MD.

Nanomedicine (Lond). 2020 Mar;15(6):543-545. doi: 10.2217/nnm-2019-0402. Epub 2020 Feb 14. No abstract available.


Passive antiamyloid immunotherapy for Alzheimer's disease.

Loureiro JC, Pais MV, Stella F, Radanovic M, Teixeira AL, Forlenza OV, de Souza LC.

Curr Opin Psychiatry. 2020 May;33(3):284-291. doi: 10.1097/YCO.0000000000000587.


Hippocampal subregions and networks linked with antidepressant response to electroconvulsive therapy.

Leaver AM, Vasavada M, Kubicki A, Wade B, Loureiro J, Hellemann G, Joshi SH, Woods RP, Espinoza R, Narr KL.

Mol Psychiatry. 2020 Feb 6. doi: 10.1038/s41380-020-0666-z. [Epub ahead of print]


Early diagnosis and treatment of Alzheimer's disease: new definitions and challenges.

Pais M, Martinez L, Ribeiro O, Loureiro J, Fernandez R, Valiengo L, Canineu P, Stella F, Talib L, Radanovic M, Forlenza OV.

Braz J Psychiatry. 2020 Jan 24. pii: S1516-44462020005001205. doi: 10.1590/1516-4446-2019-0735. [Epub ahead of print]


Ultra-High Field MRI in Alzheimer's Disease: Effective Transverse Relaxation Rate and Quantitative Susceptibility Mapping of Human Brain In Vivo and Ex Vivo compared to Histology.

Tuzzi E, Balla DZ, Loureiro JRA, Neumann M, Laske C, Pohmann R, Preische O, Scheffler K, Hagberg GE.

J Alzheimers Dis. 2020;73(4):1481-1499. doi: 10.3233/JAD-190424.


Corrigendum to "Conjugation of the T1 sequence from CCN1 to fibrin hydrogels for therapeutic vascularization" [Mater. Sci. & Eng. C. 104 (2019) 109847].

Loureiro J, Torres AL, Neto T, Aguiar P, Barrias CC, Pinto MT, Amaral IF.

Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:110514. doi: 10.1016/j.msec.2019.110514. Epub 2019 Dec 9. No abstract available.


BRCA1/P53: Two strengths in cancer chemoprevention.

Raimundo L, Ramos H, Loureiro JB, Calheiros J, Saraiva L.

Biochim Biophys Acta Rev Cancer. 2020 Jan;1873(1):188339. doi: 10.1016/j.bbcan.2020.188339. Epub 2020 Jan 7. Review.


Determinants of age at onset in a Portuguese cohort of autosomal dominant spastic paraplegia.

Rodrigues R, Silva R, Branco M, Brandão E, Alonso I, Ruano L, Loureiro JL.

J Neurol Sci. 2020 Mar 15;410:116646. doi: 10.1016/j.jns.2019.116646. Epub 2019 Dec 24.


Benchmarking network algorithms for contextualizing genes of interest.

Hill A, Gleim S, Kiefer F, Sigoillot F, Loureiro J, Jenkins J, Morris MK.

PLoS Comput Biol. 2019 Dec 20;15(12):e1007403. doi: 10.1371/journal.pcbi.1007403. eCollection 2019 Dec.


Nanotechnology to improve the Alzheimer's disease therapy with natural compounds.

Ramalho MJ, Andrade S, Loureiro JA, do Carmo Pereira M.

Drug Deliv Transl Res. 2020 Apr;10(2):380-402. doi: 10.1007/s13346-019-00694-3. Review.


Methods for the Measurement of Early Events in Toxoplasma gondii Immunity in Mouse Cells.

Alvarez C, Campos AC, Howard JC, Loureiro J, Müller UB, Rodrigues AL.

Methods Mol Biol. 2020;2071:371-409. doi: 10.1007/978-1-4939-9857-9_20.


Environmental differences are correlated with the distribution pattern of cytotypes in Veronica subsection Pentasepalae at a broad scale.

Rojas-Andrés BM, Padilla-García N, de Pedro M, López-González N, Delgado L, Albach DC, Castro M, Castro S, Loureiro J, Martínez-Ortega MM.

Ann Bot. 2020 Mar 9;125(3):471-484. doi: 10.1093/aob/mcz182.


Sustainable Fully Printed UV Sensors on Cork Using Zinc Oxide/Ethylcellulose Inks.

Figueira J, Gaspar C, Carvalho JT, Loureiro J, Fortunato E, Martins R, Pereira L.

Micromachines (Basel). 2019 Sep 12;10(9). pii: E601. doi: 10.3390/mi10090601.


SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations.

Gomes AS, Ramos H, Gomes S, Loureiro JB, Soares J, Barcherini V, Monti P, Fronza G, Oliveira C, Domingues L, Bastos M, Dourado DFAR, Carvalho AL, Romão MJ, Pinheiro B, Marcelo F, Carvalho A, Santos MMM, Saraiva L.

Biochim Biophys Acta Gen Subj. 2020 Jan;1864(1):129440. doi: 10.1016/j.bbagen.2019.129440. Epub 2019 Sep 16.


Conjugation of the T1 sequence from CCN1 to fibrin hydrogels for therapeutic vascularization.

Loureiro J, Torres AL, Neto T, Aguiar P, Barrias CC, Pinto MT, Amaral IF.

Mater Sci Eng C Mater Biol Appl. 2019 Nov;104:109847. doi: 10.1016/j.msec.2019.109847. Epub 2019 Jul 5. Erratum in: Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:110514.


SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma.

Gomes S, Bosco B, Loureiro JB, Ramos H, Raimundo L, Soares J, Nazareth N, Barcherini V, Domingues L, Oliveira C, Bisio A, Piazza S, Bauer MR, Brás JP, Almeida MI, Gomes C, Reis F, Fersht AR, Inga A, Santos MMM, Saraiva L.

Cancers (Basel). 2019 Aug 10;11(8). pii: E1151. doi: 10.3390/cancers11081151.


Factorial Design as a Tool for the Optimization of PLGA Nanoparticles for the Co-Delivery of Temozolomide and O6-Benzylguanine.

Ramalho MJ, Loureiro JA, Coelho MAN, Pereira MC.

Pharmaceutics. 2019 Aug 10;11(8). pii: E401. doi: 10.3390/pharmaceutics11080401.


Consumer-Driven Improvement of Maize Bread Formulations with Legume Fortification.

Cunha LM, Fonseca SC, Lima RC, Loureiro J, Pinto AS, Vaz Patto MC, Brites C.

Foods. 2019 Jun 29;8(7). pii: E235. doi: 10.3390/foods8070235.


Assistive technology based on client-centered for occupational performance in neuromuscular conditions.

Pousada García T, Loureiro JP, González BG, Nieto-Rivero L.

Medicine (Baltimore). 2019 Jun;98(25):e15983. doi: 10.1097/MD.0000000000015983.


Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents.

Lemos A, Gomes AS, Loureiro JB, Brandão P, Palmeira A, Pinto MMM, Saraiva L, Sousa ME.

Molecules. 2019 May 22;24(10). pii: E1975. doi: 10.3390/molecules24101975.


Elastic Registration of Single Subject Task Based fMRI Signals.

Lee DS, Loureiro J, Narr KL, Woods RP, Joshi SH.

Med Image Comput Comput Assist Interv. 2018 Sep;11072:154-162. doi: 10.1007/978-3-030-00931-1_18. Epub 2018 Sep 13.


Natural Compounds for Alzheimer's Disease Therapy: A Systematic Review of Preclinical and Clinical Studies.

Andrade S, Ramalho MJ, Loureiro JA, Pereira MDC.

Int J Mol Sci. 2019 May 10;20(9). pii: E2313. doi: 10.3390/ijms20092313.


Interaction of natural compounds with biomembrane models: A biophysical approach for the Alzheimer's disease therapy.

Andrade S, Ramalho MJ, Loureiro JA, Pereira MC.

Colloids Surf B Biointerfaces. 2019 Aug 1;180:83-92. doi: 10.1016/j.colsurfb.2019.04.019. Epub 2019 Apr 21.


A survey on the prevalence of apathy in elderly people referred to specialized memory centers.

Manera V, Fabre R, Stella F, Loureiro JC, Agüera-Ortiz L, López-Álvarez J, Hanon C, Hoertel N, Aalten P, Ramakers I, Zeghari R, Robert P.

Int J Geriatr Psychiatry. 2019 Oct;34(10):1369-1377. doi: 10.1002/gps.5125. Epub 2019 May 8.


Adaptations to a semiaquatic lifestyle in the external ear of southern pinnipeds (Otariidae and Phocidae, Carnivora): Morphological evidences.

Loza CM, Krmpotic CM, Galliari FC, Andrés Laube PF, Negrete J, Scarano AC, Loureiro J, Carlini AA, Barbeito CG.

Zoology (Jena). 2019 Apr;133:66-80. doi: 10.1016/j.zool.2019.02.006. Epub 2019 Feb 27. Review.


Solvatochromism as a new tool to distinguish structurally similar compounds.

Madeira PP, Loureiro JA, Freire MG, Coutinho JAP.

J Mol Liq. 2019 Jan 15;274:740-745. doi: 10.1016/j.molliq.2018.11.050.


Biosensor for direct bioelectrocatalysis detection of nitric oxide using nitric oxide reductase incorporated in carboxylated single-walled carbon nanotubes/lipidic 3 bilayer nanocomposite.

Gomes FO, Maia LB, Loureiro JA, Pereira MC, Delerue-Matos C, Moura I, Moura JJG, Morais S.

Bioelectrochemistry. 2019 Jun;127:76-86. doi: 10.1016/j.bioelechem.2019.01.010. Epub 2019 Feb 5.


Biophysical interaction of temozolomide and its active metabolite with biomembrane models: The relevance of drug-membrane interaction for Glioblastoma Multiforme therapy.

Ramalho MJ, Andrade S, Coelho MÁN, Loureiro JA, Pereira MC.

Eur J Pharm Biopharm. 2019 Mar;136:156-163. doi: 10.1016/j.ejpb.2019.01.015. Epub 2019 Jan 22.


New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma.

Gomes S, Raimundo L, Soares J, Loureiro JB, Leão M, Ramos H, Monteiro MN, Lemos A, Moreira J, Pinto M, Chlapek P, Veselska R, Sousa E, Saraiva L.

Cancer Lett. 2019 Apr 1;446:90-102. doi: 10.1016/j.canlet.2019.01.014. Epub 2019 Jan 19.


Variations in Hippocampal White Matter Diffusivity Differentiate Response to Electroconvulsive Therapy in Major Depression.

Kubicki A, Leaver AM, Vasavada M, Njau S, Wade B, Joshi SH, Loureiro J, Hellemann G, Woods RP, Espinoza R, Narr KL.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Mar;4(3):300-309. doi: 10.1016/j.bpsc.2018.11.003. Epub 2018 Nov 14.


Discovery of a ZIP7 inhibitor from a Notch pathway screen.

Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ.

Nat Chem Biol. 2019 Feb;15(2):179-188. doi: 10.1038/s41589-018-0200-7. Epub 2019 Jan 14.


Mutational mechanism for DAB1 (ATTTC)n insertion in SCA37: ATTTT repeat lengthening and nucleotide substitution.

Loureiro JR, Oliveira CL, Mota C, Castro AF, Costa C, Loureiro JL, Coutinho P, Martins S, Sequeiros J, Silveira I.

Hum Mutat. 2019 Apr;40(4):404-412. doi: 10.1002/humu.23704. Epub 2019 Jan 9.


Resveratrol Brain Delivery for Neurological Disorders Prevention and Treatment.

Andrade S, Ramalho MJ, Pereira MDC, Loureiro JA.

Front Pharmacol. 2018 Nov 20;9:1261. doi: 10.3389/fphar.2018.01261. eCollection 2018. Review.


Prevalence of vitamin D deficiency amongst soccer athletes and effects of 8 weeks supplementation.

Teixeira P, Santos AC, Casalta-Lopes J, Almeida M, Loureiro J, Ermida V, Caldas J, Fontes-Ribeiro C.

J Sports Med Phys Fitness. 2019 Apr;59(4):693-699. doi: 10.23736/S0022-4707.18.08551-1. Epub 2018 Oct 31.


mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level.

Zeng H, Lu B, Zamponi R, Yang Z, Wetzel K, Loureiro J, Mohammadi S, Beibel M, Bergling S, Reece-Hoyes J, Russ C, Roma G, Tchorz JS, Capodieci P, Cong F.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10362-E10369. doi: 10.1073/pnas.1808575115. Epub 2018 Oct 8.


Noninvasive brain stimulation for behavioural and psychological symptoms of dementia: A systematic review and meta-analysis.

Vacas SM, Stella F, Loureiro JC, Simões do Couto F, Oliveira-Maia AJ, Forlenza OV.

Int J Geriatr Psychiatry. 2019 Sep;34(9):1336-1345. doi: 10.1002/gps.5003. Epub 2018 Oct 17.


Synthesis of 28,28,28-trideutero-25-hydroxydihydrotachysterol2.

Sigüeiro R, Loureiro J, González-Berdullas P, Mouriño A, Maestro MA.

J Steroid Biochem Mol Biol. 2019 Jan;185:248-250. doi: 10.1016/j.jsbmb.2018.09.014. Epub 2018 Sep 19.


Risk factors for traumatic dental injuries in the Brazilian population: A critical review.

Soares TRC, Magno MB, Jural LA, Loureiro JM, Chianca TK, de Andrade Risso P, Maia LC.

Dent Traumatol. 2018 Dec;34(6):445-454. doi: 10.1111/edt.12439. Epub 2018 Oct 16. Review.


Improving anticancer activity towards colon cancer cells with a new p53-activating agent.

Raimundo L, Espadinha M, Soares J, Loureiro JB, Alves MG, Santos MMM, Saraiva L.

Br J Pharmacol. 2018 Oct;175(20):3947-3962. doi: 10.1111/bph.14468. Epub 2018 Sep 6.


Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity.

Brandão P, Loureiro JB, Carvalho S, Hamadou MH, Cravo S, Moreira J, Pereira D, Palmeira A, Pinto M, Saraiva L, Cidade H.

Eur J Med Chem. 2018 Aug 5;156:711-721. doi: 10.1016/j.ejmech.2018.07.037. Epub 2018 Jul 17.


Application of a micro-meso-structured reactor (NETmix) to promote photochemical UVC/H2O2 processes - oxidation of As(iii) to As(v).

Marinho BA, Martín de Vidales MJ, Mazur LP, Paulista L, Cristóvão RO, Mayer DA, Loureiro JM, Boaventura RAR, Dias MM, Lopes JCB, Vilar VJP.

Photochem Photobiol Sci. 2018 Sep 12;17(9):1179-1188. doi: 10.1039/c8pp00006a.


A repeat-primed PCR assay for pentanucleotide repeat alleles in spinocerebellar ataxia type 37.

Loureiro JR, Oliveira CL, Sequeiros J, Silveira I.

J Hum Genet. 2018 Sep;63(9):981-987. doi: 10.1038/s10038-018-0474-3. Epub 2018 Jun 11.


Polyploid lineages in the genus Porphyra.

Varela-Álvarez E, Loureiro J, Paulino C, Serrão EA.

Sci Rep. 2018 Jun 6;8(1):8696. doi: 10.1038/s41598-018-26796-5.


In-vivo quantitative structural imaging of the human midbrain and the superior colliculus at 9.4T.

Loureiro JR, Himmelbach M, Ethofer T, Pohmann R, Martin P, Bause J, Grodd W, Scheffler K, Hagberg GE.

Neuroimage. 2018 Aug 15;177:117-128. doi: 10.1016/j.neuroimage.2018.04.071. Epub 2018 May 2.


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