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Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum).

Fei JF, Lou WP, Knapp D, Murawala P, Gerber T, Taniguchi Y, Nowoshilow S, Khattak S, Tanaka EM.

Nat Protoc. 2018 Nov 14. doi: 10.1038/s41596-018-0071-0. [Epub ahead of print]


Identification of chemoresistance-associated miRNAs in breast cancer.

Lou W, Liu J, Ding B, Xu L, Fan W.

Cancer Manag Res. 2018 Oct 23;10:4747-4757. doi: 10.2147/CMAR.S172722. eCollection 2018.


CD25 and TGF-β blockade based on predictive integrated immune ratio inhibits tumor growth in pancreatic cancer.

Pu N, Zhao G, Yin H, Li JA, Nuerxiati A, Wang D, Xu X, Kuang T, Jin D, Lou W, Wu W.

J Transl Med. 2018 Oct 25;16(1):294. doi: 10.1186/s12967-018-1673-6.


Development of predictive prognostic nomogram for NECs of rectum on population-based exploration.

Lv Y, Pu N, Mao W, Chen W, Wang H, Han X, Ji Y, Zhang L, Jin D, Lou W, Xu X.

Endocr Connect. 2018 Sep 1. pii: /journals/ec/aop/ec-18-0353.xml. doi: 10.1530/EC-18-0353. [Epub ahead of print]


Joint distraction for knee osteoarthritis: protocol for a systematic review and meta-analysis.

Goh EL, Lou WCN, Chidambaram S, Ma S.

Syst Rev. 2018 Oct 15;7(1):162. doi: 10.1186/s13643-018-0837-z.


Identification of invasion-metastasis-associated microRNAs in hepatocellular carcinoma based on bioinformatic analysis and experimental validation.

Lou W, Chen J, Ding B, Chen D, Zheng H, Jiang D, Xu L, Bao C, Cao G, Fan W.

J Transl Med. 2018 Sep 29;16(1):266. doi: 10.1186/s12967-018-1639-8.


Loss of miR-16 contributes to tumor progression by activation of tousled-like kinase 1 in oral squamous cell carcinoma.

Hu S, Wang H, Yan D, Lu W, Gao P, Lou W, Kong X.

Cell Cycle. 2018;17(18):2284-2295. doi: 10.1080/15384101.2018.1526601. Epub 2018 Oct 9.


Frequency-specific age-related decreased brain network diversity in cognitively healthy elderly: A whole-brain data-driven analysis.

Lou W, Wang D, Wong A, Chu WCW, Mok VCT, Shi L.

Hum Brain Mapp. 2018 Sep 21. doi: 10.1002/hbm.24376. [Epub ahead of print]


Associations of sirtuins with clinicopathological parameters and prognosis in non-small cell lung cancer.

Gong J, Wang H, Lou W, Wang G, Tao H, Wen H, Liu Y, Xie Q.

Cancer Manag Res. 2018 Sep 10;10:3341-3356. doi: 10.2147/CMAR.S166946. eCollection 2018.


Postnatal exposure to household disinfectants, infant gut microbiota and subsequent risk of overweight in children.

Tun MH, Tun HM, Mahoney JJ, Konya TB, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Brook JR, Lou W, Takaro TK, Scott JA, Kozyrskyj AL; CHILD Study Investigators.

CMAJ. 2018 Sep 17;190(37):E1097-E1107. doi: 10.1503/cmaj.170809. Erratum in: CMAJ. 2018 Nov 12;190(45):E1341.


Non-coding RNA in drug resistance of hepatocellular carcinoma.

Ding B, Lou W, Xu L, Fan W.

Biosci Rep. 2018 Oct 9;38(5). pii: BSR20180915. doi: 10.1042/BSR20180915. Print 2018 Oct 31. Review.


Quantum Hall Effect in Electron-Doped Black Phosphorus Field-Effect Transistors.

Yang F, Zhang Z, Wang NZ, Ye GJ, Lou W, Zhou X, Watanabe K, Taniguchi T, Chang K, Chen XH, Zhang Y.

Nano Lett. 2018 Oct 10;18(10):6611-6616. doi: 10.1021/acs.nanolett.8b03267. Epub 2018 Sep 20.


Depleting the carboxy-terminus of human Wnt5a attenuates collagen-induced arthritis in DBA/1 mice.

Cao W, Niu M, Tong Y, Du Y, Lou W, Mao Y, Dou Y, Yuan H, Zhao W.

Biochem Biophys Res Commun. 2018 Oct 12;504(4):679-685. doi: 10.1016/j.bbrc.2018.09.030. Epub 2018 Sep 11.


Hfq, a RNA Chaperone, Contributes to Virulence by Regulating Plant Cell Wall-Degrading Enzyme Production, Type VI Secretion System Expression, Bacterial Competition, and Suppressing Host Defense Response in Pectobacterium carotovorum.

Wang C, Pu T, Lou W, Wang Y, Gao Z, Hu B, Fan J.

Mol Plant Microbe Interact. 2018 Nov;31(11):1166-1178. doi: 10.1094/MPMI-12-17-0303-R. Epub 2018 Sep 10.


Antioxidant and α-amylase inhibitory activities of tannic acid.

Lou W, Chen Y, Ma H, Liang G, Liu B.

J Food Sci Technol. 2018 Sep;55(9):3640-3646. doi: 10.1007/s13197-018-3292-x. Epub 2018 Jul 11.


MicroRNA regulation of liver cancer stem cells.

Lou W, Liu J, Gao Y, Zhong G, Ding B, Xu L, Fan W.

Am J Cancer Res. 2018 Jul 1;8(7):1126-1141. eCollection 2018. Review.


Outer Membrane Iron Uptake Pathways in the Model Cyanobacterium Synechocystis sp. Strain PCC 6803.

Qiu GW, Lou WJ, Sun CY, Yang N, Li ZK, Li DL, Zang SS, Fu FX, Hutchins DA, Jiang HB, Qiu BS.

Appl Environ Microbiol. 2018 Sep 17;84(19). pii: e01512-18. doi: 10.1128/AEM.01512-18. Print 2018 Oct 1.


Risk for Maternal Depressive Symptoms and Perceived Stress by Ethnicities in Canada: From Pregnancy Through the Preschool Years.

Dharma C, Lefebvre DL, Lu Z, Lou WYW, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Azad MB, Chen E, Elliott SJ, Kozyrskyj AL, Sears MR, Subbarao P.

Can J Psychiatry. 2018 Aug 1:706743718792190. doi: 10.1177/0706743718792190. [Epub ahead of print]


Antimicrobial polymers as therapeutics for treatment of multidrug-resistant Klebsiella pneumoniae lung infection.

Lou W, Venkataraman S, Zhong G, Ding B, Tan JPK, Xu L, Fan W, Yang YY.

Acta Biomater. 2018 Sep 15;78:78-88. doi: 10.1016/j.actbio.2018.07.038. Epub 2018 Jul 20.


A Specific Single Nucleotide Polymorphism in the ATP Synthase Gene Significantly Improves Environmental Stress Tolerance of Synechococcus elongatus PCC 7942.

Lou W, Tan X, Song K, Zhang S, Luan G, Li C, Lu X.

Appl Environ Microbiol. 2018 Aug 31;84(18). pii: e01222-18. doi: 10.1128/AEM.01222-18. Print 2018 Sep 15.


Automatic Segmentation of Acute Ischemic Stroke From DWI Using 3-D Fully Convolutional DenseNets.

Zhang R, Zhao L, Lou W, Abrigo JM, Mok VCT, Chu WCW, Wang D, Shi L.

IEEE Trans Med Imaging. 2018 Sep;37(9):2149-2160. doi: 10.1109/TMI.2018.2821244. Epub 2018 Mar 30.


Efficacy and Safety of Sunitinib in Patients with Well-Differentiated Pancreatic Neuroendocrine Tumours.

Raymond E, Kulke MH, Qin S, Yu X, Schenker M, Cubillo A, Lou W, Tomasek J, Thiis-Evensen E, Xu JM, Croitoru AE, Khasraw M, Sedlackova E, Borbath I, Ruff P, Oberstein PE, Ito T, Jia L, Hammel P, Shen L, Shrikhande SV, Shen Y, Sufliarsky J, Khan GN, Morizane C, Galdy S, Khosravan R, Fernandez KC, Rosbrook B, Fazio N.

Neuroendocrinology. 2018;107(3):237-245. doi: 10.1159/000491999. Epub 2018 Jul 10.


A Review of Recent Advances in Ultrasound, Placed in the Context of Pain Diagnosis and Treatment.

Bobola MS, Chen L, Ezeokeke CK, Kuznetsova K, Lahti AC, Lou W, Myroniv AN, Schimek NW, Selby ML, Mourad PD.

Curr Pain Headache Rep. 2018 Jul 10;22(9):60. doi: 10.1007/s11916-018-0711-7. Review.


Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation.

Lou W, Ting HC, Reynolds CA, Tyurina YY, Tyurin VA, Li Y, Ji J, Yu W, Liang Z, Stoyanovsky DA, Anthonymuthu TS, Frasso MA, Wipf P, Greenberger JS, Bayır H, Kagan VE, Greenberg ML.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1354-1368. doi: 10.1016/j.bbalip.2018.06.016. Epub 2018 Jun 20.


Impact of smartphone-assisted prenatal home visits on women's use of facility delivery: Results from a cluster-randomized trial in rural Tanzania.

Hackett K, Lafleur C, Nyella P, Ginsburg O, Lou W, Sellen D.

PLoS One. 2018 Jun 18;13(6):e0199400. doi: 10.1371/journal.pone.0199400. eCollection 2018.


IP-10 Promotes Blood-Brain Barrier Damage by Inducing Tumor Necrosis Factor Alpha Production in Japanese Encephalitis.

Wang K, Wang H, Lou W, Ma L, Li Y, Zhang N, Wang C, Li F, Awais M, Cao S, She R, Fu ZF, Cui M.

Front Immunol. 2018 May 30;9:1148. doi: 10.3389/fimmu.2018.01148. eCollection 2018.


Ventilation inhomogeneity in infants with recurrent wheezing.

Lu Z, Foong RE, Kowalik K, Moraes TJ, Boyce A, Dubeau A, Balkovec S, Gustafsson PM, Becker AB, Mandhane PJ, Turvey SE, Lou W, Ratjen F, Sears M, Subbarao P.

Thorax. 2018 Oct;73(10):936-941. doi: 10.1136/thoraxjnl-2017-211351. Epub 2018 Jun 15.


Detection of CTCs in portal vein was associated with intrahepatic metastases and prognosis in patients with advanced pancreatic cancer.

Liu X, Li C, Li J, Yu T, Zhou G, Cheng J, Li G, Zhou Y, Lou W, Wang X, Gong G, Liu L, Chen Y.

J Cancer. 2018 May 22;9(11):2038-2045. doi: 10.7150/jca.23989. eCollection 2018.


The application of deep eutectic solvent on the extraction and in vitro antioxidant activity of rutin from Sophora japonica bud.

Peng F, Xu P, Zhao BY, Zong MH, Lou WY.

J Food Sci Technol. 2018 Jun;55(6):2326-2333. doi: 10.1007/s13197-018-3151-9. Epub 2018 Apr 27.


Intra versus Inter Cross-resistance Determines Treatment Sequence between Taxane and AR-Targeting Therapies in Advanced Prostate Cancer.

Lombard AP, Liu L, Cucchiara V, Liu C, Armstrong CM, Zhao R, Yang JC, Lou W, Evans CP, Gao AC.

Mol Cancer Ther. 2018 Oct;17(10):2197-2205. doi: 10.1158/1535-7163.MCT-17-1269. Epub 2018 Jun 11.


Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex.

Chan TE, Grossman YS, Bloss EB, Janssen WG, Lou W, McEwen BS, Dumitriu D, Morrison JH.

Front Aging Neurosci. 2018 May 23;10:146. doi: 10.3389/fnagi.2018.00146. eCollection 2018.


Application of a novel embeddedness-like pancreaticojejunostomy anastomosis technique used in pancreaticoduodenectomy.

Xu X, Lv Y, Zhang L, Xin B, Li JA, Wang D, Kuang T, Lou W, Jin D.

Oncol Lett. 2018 May;15(5):8067-8071. doi: 10.3892/ol.2018.8334. Epub 2018 Mar 23.


Lactic dehydrogenase to albumin ratio in prediction of unresectable pancreatic cancer with intervention chemotherapy.

Gao S, Wu M, Chen Y, Lou W, Zhou G, Li J, Yu T, Zhou Y, Liu L, Wang X.

Future Oncol. 2018 Jun;14(14):1377-1386. doi: 10.2217/fon-2017-0556. Epub 2018 May 31.


Permanent maxillary central incisor and first molar rotations in the mixed dentition in repaired complete unilateral cleft lip and palate and their relationship with absence of teeth in their vicinity.

Suri S, Disthaporn S, Ross B, Tompson B, Baena D, Fisher D, Lou W.

Angle Orthod. 2018 Sep;88(5):567-574. doi: 10.2319/121117-856.1. Epub 2018 May 25.


Reference equations for the interpretation of forced expiratory and plethysmographic measurements in infants.

Lu Z, Foong RE, Kowalik K, Moraes TJ, Dubeau A, Lefebvre D, Davis SD, Balkovec S, Becker A, Mandhane P, Turvey SE, Lou W, Sears MR, Ratjen F, Subbarao P.

Pediatr Pulmonol. 2018 Jul;53(7):907-916. doi: 10.1002/ppul.24063. Epub 2018 May 23.


[Prognostic analysis and clinicopathological features of 20 patients with appendiceal neuroendocrine neoplasms].

Mao W, Lyu Y, Pu N, Li J, Xin B, Chen W, Jin D, Lou W, Xu X.

Zhonghua Wei Chang Wai Ke Za Zhi. 2018 May 25;21(5):564-568. Chinese.


The latest exploration of staging and prognostic classification for pancreatic neuroendocrine tumors: a large population-based study.

Gao S, Pu N, Liu L, Li C, Xu X, Wang X, Lou W.

J Cancer. 2018 Apr 19;9(9):1698-1706. doi: 10.7150/jca.24178. eCollection 2018.


Extraction, purification and antioxidant activity of novel polysaccharides from Dendrobium officinale by deep eutectic solvents.

Liang J, Zeng Y, Wang H, Lou W.

Nat Prod Res. 2018 May 4:1-6. doi: 10.1080/14786419.2018.1471480. [Epub ahead of print]


Efficacy and safety comparison of nabpaclitaxel plus S-1 and gemcitabine plus S-1 as first-line chemotherapy for metastatic pancreatic cancer.

Xu Y, Guo X, Fan Y, Wang D, Wu W, Wu L, Liu T, Xu B, Feng Y, Wang Y, Lou W, Zhou Y.

Jpn J Clin Oncol. 2018 Jun 1;48(6):535-541. doi: 10.1093/jjco/hyy063.


Loss of tafazzin results in decreased myoblast differentiation in C2C12 cells: A myoblast model of Barth syndrome and cardiolipin deficiency.

Lou W, Reynolds CA, Li Y, Liu J, Hüttemann M, Schlame M, Stevenson D, Strathdee D, Greenberg ML.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug;1863(8):857-865. doi: 10.1016/j.bbalip.2018.04.015. Epub 2018 Apr 22.


[Effects of inorganic carbon supplies and light on photosynthetic functions of Pyropia haitanensis.]

Jiang H, Zou DH, Lou WY.

Ying Yong Sheng Tai Xue Bao. 2018 Feb;29(2):515-521. doi: 10.13287/j.1001-9332.201802.010. Chinese.


Atrophic inferior vena cava is a marker of chronicity of intra-filter and inferior vena cava thrombosis: based on CT findings.

Chen L, Shi W, Gu J, He X, Lou W.

BMC Cardiovasc Disord. 2018 Apr 11;18(1):64. doi: 10.1186/s12872-018-0799-z.


Prevention of upper gastrointestinal bleeding in critically ill Chinese patients: a randomized, double-blind study evaluating esomeprazole and cimetidine.

Lou W, Xia Y, Xiang P, Zhang L, Yu X, Lim S, Xu M, Zhao L, Rydholm H, Traxler B, Qin X.

Curr Med Res Opin. 2018 Aug;34(8):1449-1455. doi: 10.1080/03007995.2018.1464132. Epub 2018 Apr 20.


A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset.

Chin W, Zhong G, Pu Q, Yang C, Lou W, De Sessions PF, Periaswamy B, Lee A, Liang ZC, Ding X, Gao S, Chu CW, Bianco S, Bao C, Tong YW, Fan W, Wu M, Hedrick JL, Yang YY.

Nat Commun. 2018 Mar 2;9(1):917. doi: 10.1038/s41467-018-03325-6.


Clinicopathological Characteristics of the primary and metastatic Hepatic Neuroendocrine Tumors and the relevant Prognosis-Related Factors: A Retrospective Study of 81 Cases in a Single Chinese Center.

Lv Y, Huang C, Xu H, Han X, Zhang L, Mao W, Ji Y, Jin D, Lou W, Xu X.

J Cancer. 2018 Jan 1;9(3):479-487. doi: 10.7150/jca.22157. eCollection 2018.


Clinical relevance of different WHO grade 3 pancreatic neuroendocrine neoplasms based on morphology.

Han X, Xu X, Ma H, Ji Y, Wang D, Kuang T, Wu W, Song B, Li G, Jin G, Lou W.

Endocr Connect. 2018 Feb;7(2):355-363. doi: 10.1530/EC-17-0388.


Comparison of prognostic prediction between nomogram based on lymph node ratio and AJCC 8th staging system for patients with resected pancreatic head carcinoma: a SEER analysis.

Pu N, Li J, Xu Y, Lee W, Fang Y, Han X, Zhao G, Zhang L, Nuerxiati A, Yin H, Wu W, Lou W.

Cancer Manag Res. 2018 Feb 5;10:227-238. doi: 10.2147/CMAR.S157940. eCollection 2018.


A new panel of pancreatic cancer biomarkers discovered using a mass spectrometry-based pipeline.

Liu X, Zheng W, Wang W, Shen H, Liu L, Lou W, Wang X, Yang P.

Br J Cancer. 2018 Mar 20;118(6):e15. doi: 10.1038/bjc.2018.5. Epub 2018 Feb 13.


miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells.

Chen D, Si W, Shen J, Du C, Lou W, Bao C, Zheng H, Pan J, Zhong G, Xu L, Fu P, Fan W.

Cell Death Dis. 2018 Feb 7;9(2):188. doi: 10.1038/s41419-017-0211-4.

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