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Items: 1 to 50 of 87

1.

Recurrent optic neuritis - Different patterns in multiple sclerosis, neuromyelitis optica spectrum disorders and MOG-antibody disease.

Lotan I, Hellmann MA, Benninger F, Stiebel-Kalish H, Steiner I.

J Neuroimmunol. 2018 Nov 15;324:115-118. doi: 10.1016/j.jneuroim.2018.09.010. Epub 2018 Sep 22.

PMID:
30267996
2.

Myelin oligodendrocyte glycoprotein-positive optic neuritis masquerading as pseudotumor cerebri at presentation.

Lotan I, Brody J, Hellmann MA, Bialer O, Ganelin-Cohen E, Michaeli N, Marignier R, Stiebel-Kalish H.

J Neurol. 2018 Sep;265(9):1985-1988. doi: 10.1007/s00415-018-8956-y. Epub 2018 Jun 25.

PMID:
29938337
3.

The Dual Function of the Polybasic Juxtamembrane Region of Syntaxin 1A in Clamping Spontaneous Release and Stimulating Ca2+-Triggered Release in Neuroendocrine Cells.

Singer-Lahat D, Barak-Broner N, Sheinin A, Greitzer-Antes D, Michaelevski I, Lotan I.

J Neurosci. 2018 Jan 3;38(1):220-231. doi: 10.1523/JNEUROSCI.1541-17.2017. Epub 2017 Nov 13.

4.

Giant cell arteritis following varicella zoster vaccination.

Lotan I, Steiner I.

J Neurol Sci. 2017 Apr 15;375:158-159. doi: 10.1016/j.jns.2017.01.053. Epub 2017 Jan 18.

PMID:
28320119
5.

Retinal Nerve Fiber Layer May Be Better Preserved in MOG-IgG versus AQP4-IgG Optic Neuritis: A Cohort Study.

Stiebel-Kalish H, Lotan I, Brody J, Chodick G, Bialer O, Marignier R, Bach M, Hellmann MA.

PLoS One. 2017 Jan 26;12(1):e0170847. doi: 10.1371/journal.pone.0170847. eCollection 2017.

6.

Neuromyelitis Optica Spectrum Disorder: Disease Course and Long-Term Visual Outcome.

Brody J, Hellmann MA, Marignier R, Lotan I, Stiebel-Kalish H.

J Neuroophthalmol. 2016 Dec;36(4):356-362.

PMID:
27348750
7.

Psychiatric side effects of acute high-dose corticosteroid therapy in neurological conditions.

Lotan I, Fireman L, Benninger F, Weizman A, Steiner I.

Int Clin Psychopharmacol. 2016 Jul;31(4):224-31. doi: 10.1097/YIC.0000000000000122.

PMID:
26938038
8.

Prior damage to lower motor neuron triggering myasthenia gravis.

Steiner I, Goldstein L, Hellmann MA, Lotan I.

Muscle Nerve. 2016 Jun;54(1):167-9. doi: 10.1002/mus.25026. No abstract available.

PMID:
26789735
9.

Atypical case of Morvan's syndrome.

Lotan I, Djaldetti R, Hellman MA, Benninger F.

J Clin Neurosci. 2016 Mar;25:132-4. doi: 10.1016/j.jocn.2015.06.025. Epub 2015 Nov 6.

PMID:
26549678
10.

Regulation of the neuronal KCNQ2 channel by Src--a dual rearrangement of the cytosolic termini underlies bidirectional regulation of gating.

Siloni S, Singer-Lahat D, Esa M, Tsemakhovich V, Chikvashvili D, Lotan I.

J Cell Sci. 2015 Sep 15;128(18):3489-501. doi: 10.1242/jcs.173922. Epub 2015 Aug 14.

11.

GABAB receptor deficiency causes failure of neuronal homeostasis in hippocampal networks.

Vertkin I, Styr B, Slomowitz E, Ofir N, Shapira I, Berner D, Fedorova T, Laviv T, Barak-Broner N, Greitzer-Antes D, Gassmann M, Bettler B, Lotan I, Slutsky I.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3291-9. doi: 10.1073/pnas.1424810112. Epub 2015 Jun 8.

12.

DJ-1 knockout augments disease severity and shortens survival in a mouse model of ALS.

Lev N, Barhum Y, Lotan I, Steiner I, Offen D.

PLoS One. 2015 Mar 30;10(3):e0117190. doi: 10.1371/journal.pone.0117190. eCollection 2015.

13.

Diagnostic criteria of chronic inflammatory demyelinating polyneuropathy in diabetes mellitus.

Lotan I, Hellman MA, Steiner I.

Acta Neurol Scand. 2015 Oct;132(4):278-83. doi: 10.1111/ane.12394. Epub 2015 Mar 25.

PMID:
25819084
14.

A 66-year-old patient with progressive left hemiparesis: question.

Lotan I, Djaldetti R, Luckman J, Siegal T, Steiner I.

J Clin Neurosci. 2014 Nov;21(11):1966, 2031. No abstract available.

PMID:
25587611
15.

Tumefactive demyelination and a malignant course in an MS patient during and following fingolimod therapy.

Hellmann MA, Lev N, Lotan I, Mosberg-Galili R, Inbar E, Luckman J, Fichman-Horn S, Yakimov M, Steiner I.

J Neurol Sci. 2014 Sep 15;344(1-2):193-7. doi: 10.1016/j.jns.2014.06.013. Epub 2014 Jun 17.

PMID:
25001515
16.

Syntaxin-binding domain of Kv2.1 is essential for the expression of apoptotic K+ currents.

McCord MC, Kullmann PH, He K, Hartnett KA, Horn JP, Lotan I, Aizenman E.

J Physiol. 2014 Aug 15;592(16):3511-21. doi: 10.1113/jphysiol.2014.276964. Epub 2014 Jun 13.

17.

Cannabis (medical marijuana) treatment for motor and non-motor symptoms of Parkinson disease: an open-label observational study.

Lotan I, Treves TA, Roditi Y, Djaldetti R.

Clin Neuropharmacol. 2014 Mar-Apr;37(2):41-4. doi: 10.1097/WNF.0000000000000016.

PMID:
24614667
18.

Maintenance IVIg therapy in myasthenia gravis does not affect disease activity.

Hellmann MA, Mosberg-Galili R, Lotan I, Steiner I.

J Neurol Sci. 2014 Mar 15;338(1-2):39-42. doi: 10.1016/j.jns.2013.10.043. Epub 2013 Nov 6.

PMID:
24267740
19.

Tracking Ca2+-dependent and Ca2+-independent conformational transitions in syntaxin 1A during exocytosis in neuroendocrine cells.

Greitzer-Antes D, Barak-Broner N, Berlin S, Oron Y, Chikvashvili D, Lotan I.

J Cell Sci. 2013 Jul 1;126(Pt 13):2914-23. doi: 10.1242/jcs.124743. Epub 2013 May 2.

20.

The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.

Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AM, Gaisano HY, Lotan I, Macdonald PE.

Diabetologia. 2012 Jun;55(6):1709-20. doi: 10.1007/s00125-012-2512-6. Epub 2012 Mar 13.

PMID:
22411134
21.

Primary brain T-cell lymphoma in an HTLV-1 serologically positive male.

Lotan I, Khlebtovsky A, Inbar E, Strenov J, Djaldetti R, Steiner I.

J Neurol Sci. 2012 Mar 15;314(1-2):163-5. doi: 10.1016/j.jns.2011.10.024. Epub 2011 Nov 26.

PMID:
22118868
22.

Regulation of neuronal M-channel gating in an isoform-specific manner: functional interplay between calmodulin and syntaxin 1A.

Etzioni A, Siloni S, Chikvashvilli D, Strulovich R, Sachyani D, Regev N, Greitzer-Antes D, Hirsch JA, Lotan I.

J Neurosci. 2011 Oct 5;31(40):14158-71. doi: 10.1523/JNEUROSCI.2666-11.2011.

23.

Role of neuronal potassium M-channels in sympathetic regulation of cardiac function.

Michaelevski I, Lotan I.

J Physiol. 2011 Jun 1;589(Pt 11):2659-60. doi: 10.1113/jphysiol.2011.210161. No abstract available.

24.

Non-conducting function of the Kv2.1 channel enables it to recruit vesicles for release in neuroendocrine and nerve cells.

Feinshreiber L, Singer-Lahat D, Friedrich R, Matti U, Sheinin A, Yizhar O, Nachman R, Chikvashvili D, Rettig J, Ashery U, Lotan I.

J Cell Sci. 2010 Jun 1;123(Pt 11):1940-7. doi: 10.1242/jcs.063719.

25.

Rearrangements in the relative orientation of cytoplasmic domains induced by a membrane-anchored protein mediate modulations in Kv channel gating.

Lvov A, Greitzer D, Berlin S, Chikvashvili D, Tsuk S, Lotan I, Michaelevski I.

J Biol Chem. 2009 Oct 9;284(41):28276-91. doi: 10.1074/jbc.M109.028761. Epub 2009 Aug 18.

26.

Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity.

Regev N, Degani-Katzav N, Korngreen A, Etzioni A, Siloni S, Alaimo A, Chikvashvili D, Villarroel A, Attali B, Lotan I.

PLoS One. 2009 Aug 13;4(8):e6586. doi: 10.1371/journal.pone.0006586.

27.

Syntaxin modulates Kv1.1 through dual action on channel surface expression and conductance.

Feinshreiber L, Chikvashvili D, Michaelevski I, Lotan I.

Biochemistry. 2009 May 19;48(19):4109-14. doi: 10.1021/bi9002088.

PMID:
19331362
28.

Voltage-gated potassium channel as a facilitator of exocytosis.

Feinshreiber L, Singer-Lahat D, Ashery U, Lotan I.

Ann N Y Acad Sci. 2009 Jan;1152:87-92. doi: 10.1111/j.1749-6632.2008.03997.x. Review.

PMID:
19161379
29.

Formation of the full SNARE complex eliminates interactions of its individual protein components with the Kv2.1 channel.

Tsuk S, Lvov A, Michaelevski I, Chikvashvili D, Lotan I.

Biochemistry. 2008 Aug 12;47(32):8342-9. doi: 10.1021/bi800512p. Epub 2008 Jul 18.

PMID:
18636750
30.

VAMP2 interacts directly with the N terminus of Kv2.1 to enhance channel inactivation.

Lvov A, Chikvashvili D, Michaelevski I, Lotan I.

Pflugers Arch. 2008 Sep;456(6):1121-36. doi: 10.1007/s00424-008-0468-7. Epub 2008 Jun 10.

PMID:
18542995
31.

Direct interaction of endogenous Kv channels with syntaxin enhances exocytosis by neuroendocrine cells.

Singer-Lahat D, Chikvashvili D, Lotan I.

PLoS One. 2008 Jan 2;3(1):e1381. doi: 10.1371/journal.pone.0001381.

32.

Interaction of syntaxin with a single Kv1.1 channel: a possible mechanism for modulating neuronal excitability.

Michaelevski I, Korngreen A, Lotan I.

Pflugers Arch. 2007 Jun;454(3):477-94. Epub 2007 Mar 31.

PMID:
17401576
33.

K+ channel facilitation of exocytosis by dynamic interaction with syntaxin.

Singer-Lahat D, Sheinin A, Chikvashvili D, Tsuk S, Greitzer D, Friedrich R, Feinshreiber L, Ashery U, Benveniste M, Levitan ES, Lotan I.

J Neurosci. 2007 Feb 14;27(7):1651-8.

34.

Phosphorylation of SPICK2, an AKT2 channel homologue from Samanea motor cells.

Yu L, Becker D, Levi H, Moshelion M, Hedrich R, Lotan I, Moran A, Pick U, Naveh L, Libal Y, Moran N.

J Exp Bot. 2006;57(14):3583-94. Epub 2006 Sep 12.

PMID:
16968880
35.

Advances in methods and algorithms in a modern quantum chemistry program package.

Shao Y, Molnar LF, Jung Y, Kussmann J, Ochsenfeld C, Brown ST, Gilbert AT, Slipchenko LV, Levchenko SV, O'Neill DP, DiStasio RA Jr, Lochan RC, Wang T, Beran GJ, Besley NA, Herbert JM, Lin CY, Van Voorhis T, Chien SH, Sodt A, Steele RP, Rassolov VA, Maslen PE, Korambath PP, Adamson RD, Austin B, Baker J, Byrd EF, Dachsel H, Doerksen RJ, Dreuw A, Dunietz BD, Dutoi AD, Furlani TR, Gwaltney SR, Heyden A, Hirata S, Hsu CP, Kedziora G, Khalliulin RZ, Klunzinger P, Lee AM, Lee MS, Liang W, Lotan I, Nair N, Peters B, Proynov EI, Pieniazek PA, Rhee YM, Ritchie J, Rosta E, Sherrill CD, Simmonett AC, Subotnik JE, Woodcock HL 3rd, Zhang W, Bell AT, Chakraborty AK, Chipman DM, Keil FJ, Warshel A, Hehre WJ, Schaefer HF 3rd, Kong J, Krylov AI, Gill PM, Head-Gordon M.

Phys Chem Chem Phys. 2006 Jul 21;8(27):3172-91. Epub 2006 Jun 12. Review.

PMID:
16902710
36.
37.

An Analytical Electrostatic Model for Salt Screened Interactions between Multiple Proteins.

Lotan I, Head-Gordon T.

J Chem Theory Comput. 2006 May;2(3):541-55. doi: 10.1021/ct050263p.

PMID:
26626662
38.

Algorithm and data structures for efficient energy maintenance during Monte Carlo simulation of proteins.

Lotan I, Schwarzer F, Halperin D, Latombe JC.

J Comput Biol. 2004;11(5):902-32.

PMID:
15700409
39.

Real-space protein-model completion: an inverse-kinematics approach.

van den Bedem H, Lotan I, Latombe JC, Deacon AM.

Acta Crystallogr D Biol Crystallogr. 2005 Jan;61(Pt 1):2-13. Epub 2004 Dec 17.

PMID:
15608370
40.
41.

Approximation of protein structure for fast similarity measures.

Lotan I, Schwarzer F.

J Comput Biol. 2004;11(2-3):299-317.

PMID:
15285894
42.

Direct interaction of target SNAREs with the Kv2.1 channel. Modal regulation of channel activation and inactivation gating.

Michaelevski I, Chikvashvili D, Tsuk S, Singer-Lahat D, Kang Y, Linial M, Gaisano HY, Fili O, Lotan I.

J Biol Chem. 2003 Sep 5;278(36):34320-30. Epub 2003 Jun 13.

43.

Syntaxin 1A binds to the cytoplasmic C terminus of Kv2.1 to regulate channel gating and trafficking.

Leung YM, Kang Y, Gao X, Xia F, Xie H, Sheu L, Tsuk S, Lotan I, Tsushima RG, Gaisano HY.

J Biol Chem. 2003 May 9;278(19):17532-8. Epub 2003 Mar 5.

44.

Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus.

MacDonald PE, Wang G, Tsuk S, Dodo C, Kang Y, Tang L, Wheeler MB, Cattral MS, Lakey JR, Salapatek AM, Lotan I, Gaisano HY.

Mol Endocrinol. 2002 Nov;16(11):2452-61.

PMID:
12403834
45.

Modulation of a brain voltage-gated K+ channel by syntaxin 1A requires the physical interaction of Gbetagamma with the channel.

Michaelevski I, Chikvashvili D, Tsuk S, Fili O, Lohse MJ, Singer-Lahat D, Lotan I.

J Biol Chem. 2002 Sep 20;277(38):34909-17. Epub 2002 Jul 11.

46.

Domain 2 of Drosophila para voltage-gated sodium channel confers insect properties to a rat brain channel.

Shichor I, Zlotkin E, Ilan N, Chikashvili D, Stuhmer W, Gordon D, Lotan I.

J Neurosci. 2002 Jun 1;22(11):4364-71.

47.

The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells.

Ji J, Tsuk S, Salapatek AM, Huang X, Chikvashvili D, Pasyk EA, Kang Y, Sheu L, Tsushima R, Diamant N, Trimble WS, Lotan I, Gaisano HY.

J Biol Chem. 2002 Jun 7;277(23):20195-204. Epub 2002 Mar 29.

48.

Direct interaction of a brain voltage-gated K+ channel with syntaxin 1A: functional impact on channel gating.

Fili O, Michaelevski I, Bledi Y, Chikvashvili D, Singer-Lahat D, Boshwitz H, Linial M, Lotan I.

J Neurosci. 2001 Mar 15;21(6):1964-74.

49.

Imaging plasma membrane proteins in large membrane patches of Xenopus oocytes.

Singer-Lahat D, Dascal N, Mittelman L, Peleg S, Lotan I.

Pflugers Arch. 2000 Aug;440(4):627-33.

PMID:
10958347
50.

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