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Items: 1 to 50 of 258

1.

Time to diagnosis in Cushing's syndrome: A meta-analysis based on 5367 patients.

Rubinstein G, Osswald A, Hoster E, Losa M, Elenkova A, Zacharieva S, Machado MC, Hanzu FA, Zopp S, Ritzel K, Riester A, Braun LT, Kreitschmann-Andermahr I, Storr HL, Bansal P, Barahona MJ, Cosaro E, Dogansen SC, Johnston PC, Santos de Oliveira R, Raftopoulos C, Scaroni C, Valassi E, van der Werff SJA, Schopohl J, Beuschlein F, Reincke M.

J Clin Endocrinol Metab. 2019 Oct 29. pii: dgz136. doi: 10.1210/clinem/dgz136. [Epub ahead of print]

PMID:
31665382
2.

A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update.

Giustina A, Barkan A, Beckers A, Biermasz N, Biller BMK, Boguszewski C, Bolanowski M, Bonert V, Bronstein MD, Casanueva FF, Clemmons D, Colao A, Ferone D, Fleseriu M, Frara S, Gadelha MR, Ghigo E, Gurnell M, Heaney AP, Ho K, Ioachimescu A, Katznelson L, Kelestimur F, Kopchick J, Krsek M, Lamberts S, Losa M, Luger A, Maffei P, Marazuela M, Mazziotti G, Mercado M, Mortini P, Neggers S, Pereira AM, Petersenn S, Puig-Domingo M, Salvatori R, Shimon I, Strasburger C, Tsagarakis S, van der Lely AJ, Wass J, Zatelli MC, Melmed S.

J Clin Endocrinol Metab. 2019 Oct 13. pii: dgz096. doi: 10.1210/clinem/dgz096. [Epub ahead of print]

PMID:
31606735
3.

Primary sellar melanocytoma: report of two cases treated at the same institution and their long-term outcome.

Albano L, Losa M, Spatola G, Panni P, Terreni MR, Barzaghi LR, Mortini P.

Br J Neurosurg. 2019 Sep 20:1-5. doi: 10.1080/02688697.2019.1667485. [Epub ahead of print]

PMID:
31538490
4.

Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer.

Di Mitri D, Mirenda M, Vasilevska J, Calcinotto A, Delaleu N, Revandkar A, Gil V, Boysen G, Losa M, Mosole S, Pasquini E, D'Antuono R, Masetti M, Zagato E, Chiorino G, Ostano P, Rinaldi A, Gnetti L, Graupera M, Martins Figueiredo Fonseca AR, Pereira Mestre R, Waugh D, Barry S, De Bono J, Alimonti A.

Cell Rep. 2019 Aug 20;28(8):2156-2168.e5. doi: 10.1016/j.celrep.2019.07.068.

5.

USP8 MUTANT CORTICOTROPE ADENOMAS PRESENT UNIQUE SECRETORY AND MOLECULAR FEATURES AND SHED LIGHT ON THE ROLE OF UBIQUITYLATION ON ACTH PROCESSING.

Sesta A, Cassarino MF, Terreni M, Ambrogio AG, Libera L, Bardelli D, Lasio G, Losa M, Pecori Giraldi F.

Neuroendocrinology. 2019 Jul 4. doi: 10.1159/000500688. [Epub ahead of print] No abstract available.

6.

Short-term evaluation of cardiac morphology, function, metabolism and structure following diagnosis of adult-onset growth hormone deficiency.

De Cobelli F, Rossini A, Esposito A, Canu T, Manzoni G, Del Maschio A, Rubinacci A, Sirtori M, Losa M, Lanzi R, Perseghin G.

Growth Horm IGF Res. 2019 Jun - Aug;46-47:50-54. doi: 10.1016/j.ghir.2019.06.003. Epub 2019 Jun 25.

PMID:
31276905
7.

Pituitary adenomas in elderly patients: clinical and surgical outcome analysis in a large series.

Spina A, Losa M, Mortini P.

Endocrine. 2019 Sep;65(3):637-645. doi: 10.1007/s12020-019-01959-0. Epub 2019 Jun 17.

PMID:
31209675
8.

Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer.

Civenni G, Bosotti R, Timpanaro A, Vàzquez R, Merulla J, Pandit S, Rossi S, Albino D, Allegrini S, Mitra A, Mapelli SN, Vierling L, Giurdanella M, Marchetti M, Paganoni A, Rinaldi A, Losa M, Mira-Catò E, D'Antuono R, Morone D, Rezai K, D'Ambrosio G, Ouafik L, Mackenzie S, Riveiro ME, Cvitkovic E, Carbone GM, Catapano CV.

Cell Metab. 2019 Aug 6;30(2):303-318.e6. doi: 10.1016/j.cmet.2019.05.004. Epub 2019 May 23.

PMID:
31130467
9.

Pretreatment with somatostatin analogs does not affect the anesthesiologic management of patients with acromegaly.

Losa M, Donofrio CA, Gemma M, Barzaghi LR, Mortini P.

Pituitary. 2019 Apr;22(2):187-194. doi: 10.1007/s11102-019-00952-0.

PMID:
30826981
10.

Safety and efficacy of multisession gamma knife radiosurgery for residual or recurrent pituitary adenomas.

Albano L, Losa M, Nadin F, Barzaghi LR, Parisi V, Del Vecchio A, Bolognesi A, Mortini P.

Endocrine. 2019 Jun;64(3):639-647. doi: 10.1007/s12020-019-01876-2. Epub 2019 Feb 23.

PMID:
30798432
11.

Bilateral inferior petrosal sinus sampling in adrenocorticotropin-dependent hypercortisolism: always, never, or sometimes?

Losa M, Allora A, Panni P, Righi C, Mortini P.

J Endocrinol Invest. 2019 Aug;42(8):997-1000. doi: 10.1007/s40618-019-1006-5. Epub 2019 Jan 11. No abstract available.

PMID:
30635826
12.

Sublabial transsphenoidal microsurgical technique to treat congenital transsphenoidal encephalocele: a technical note.

Albano L, Parisi V, Acerno S, Barzaghi LR, Losa M, Mortini P.

Neurosurg Rev. 2019 Jun;42(2):571-575. doi: 10.1007/s10143-018-01075-z. Epub 2019 Jan 4.

PMID:
30607614
13.

An Infratentorial Tumor in a 44-Year-Old Female Patient.

Losa M, Carta MC, Frontzek K, Krayenbühl N, Wichmann W, Rushing EJ.

Brain Pathol. 2019 Jan;29(1):145-146. doi: 10.1111/bpa.12684. No abstract available.

PMID:
30600598
14.

Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy.

Rumping L, Büttner B, Maier O, Rehmann H, Lequin M, Schlump JU, Schmitt B, Schiebergen-Bronkhorst B, Prinsen HCMT, Losa M, Fingerhut R, Lemke JR, Zwartkruis FJT, Houwen RHJ, Jans JJM, Verhoeven-Duif NM, van Hasselt PM, Jamra R.

JAMA Neurol. 2019 Mar 1;76(3):342-350. doi: 10.1001/jamaneurol.2018.2941.

PMID:
30575854
15.

Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas.

Losa M, Mortini P, Pagnano A, Detomas M, Cassarino MF, Pecori Giraldi F.

Endocrine. 2019 Feb;63(2):240-246. doi: 10.1007/s12020-018-1776-0. Epub 2018 Oct 12.

PMID:
30315484
16.

Paradoxical GH Increase During OGTT Is Associated With First-Generation Somatostatin Analog Responsiveness in Acromegaly.

Scaroni C, Albiger N, Daniele A, Dassie F, Romualdi C, Vazza G, Regazzo D, Ferraù F, Barresi V, Maffeis V, Gardiman MP, Cannavò S, Maffei P, Ceccato F, Losa M, Occhi G.

J Clin Endocrinol Metab. 2019 Mar 1;104(3):856-862. doi: 10.1210/jc.2018-01360.

PMID:
30285115
17.

High Prevalence of Radiological Vertebral Fractures in Patients With TSH-Secreting Pituitary Adenoma.

Frara S, Losa M, Doga M, Formenti AM, Mortini P, Mazziotti G, Giustina A.

J Endocr Soc. 2018 Jul 27;2(9):1089-1099. doi: 10.1210/js.2018-00091. eCollection 2018 Sep 1. Erratum in: J Endocr Soc. 2018 Dec 28;3(2):358.

18.

Publisher Correction: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.

Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, de Bono J, Carracedo A, Alimonti A.

Nat Genet. 2018 Sep;50(9):1343. doi: 10.1038/s41588-018-0181-1.

PMID:
30089860
19.

Single fraction and multisession Gamma Knife radiosurgery for craniopharyngioma.

Losa M, Pieri V, Bailo M, Gagliardi F, Barzaghi LR, Gioia L, Del Vecchio A, Bolognesi A, Mortini P.

Pituitary. 2018 Oct;21(5):499-506. doi: 10.1007/s11102-018-0903-5.

PMID:
30043097
20.

IL-23 secreted by myeloid cells drives castration-resistant prostate cancer.

Calcinotto A, Spataro C, Zagato E, Di Mitri D, Gil V, Crespo M, De Bernardis G, Losa M, Mirenda M, Pasquini E, Rinaldi A, Sumanasuriya S, Lambros MB, Neeb A, Lucianò R, Bravi CA, Nava-Rodrigues D, Dolling D, Prayer-Galetti T, Ferreira A, Briganti A, Esposito A, Barry S, Yuan W, Sharp A, de Bono J, Alimonti A.

Nature. 2018 Jul;559(7714):363-369. doi: 10.1038/s41586-018-0266-0. Epub 2018 Jun 27.

21.

Gene expression profiling in human corticotroph tumours reveals distinct, neuroendocrine profiles.

Cassarino MF, Ambrogio AG, Cassarino A, Terreni MR, Gentilini D, Sesta A, Cavagnini F, Losa M, Pecori Giraldi F.

J Neuroendocrinol. 2018 Sep;30(9):e12628. doi: 10.1111/jne.12628. Epub 2018 Aug 7.

22.

PET Evaluation of Late Cerebral Effect in Advanced Radiation Therapy Techniques for Cranial Base Tumors.

Alongi P, Iaccarino L, Losa M, Del Vecchio A, Gerevini S, Plebani V, Di Muzio N, Mortini P, Gianolli L, Perani D.

Curr Radiopharm. 2018;11(2):86-91. doi: 10.2174/1874471011666180525134301.

PMID:
29804540
23.

Pediatric Pituitary Adenomas: Early and Long-Term Surgical Outcome in a Series of 85 Consecutive Patients.

Barzaghi LR, Losa M, Capitanio JF, Albano L, Weber G, Mortini P.

Neurosurgery. 2019 Jul 1;85(1):65-74. doi: 10.1093/neuros/nyy204.

PMID:
29790934
24.

Analysis of characteristics and outcomes by growth hormone treatment duration in adult patients in the Italian cohort of the Hypopituitary Control and Complications Study (HypoCCS).

Rochira V, Mossetto G, Jia N, Cannavo S, Beck-Peccoz P, Aimaretti G, Ambrosio MR, Di Somma C, Losa M, Ferone D, Lubrano C, Scaroni C, Giampietro A, Corsello SM, Poggi M.

J Endocrinol Invest. 2018 Nov;41(11):1259-1266. doi: 10.1007/s40618-018-0860-x. Epub 2018 Mar 13.

25.

Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion.

Losa M, Risolino M, Li B, Hart J, Quintana L, Grishina I, Yang H, Choi IF, Lewicki P, Khan S, Aho R, Feenstra J, Vincent CT, Brown AMC, Ferretti E, Williams T, Selleri L.

Development. 2018 Mar 1;145(5). pii: dev157628. doi: 10.1242/dev.157628.

26.

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.

Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, Bono J, Carracedo A, Alimonti A.

Nat Genet. 2018 Feb;50(2):219-228. doi: 10.1038/s41588-017-0026-3. Epub 2018 Jan 15. Erratum in: Nat Genet. 2018 Sep;50(9):1343.

27.

Expression of SRY-related HMG Box Transcription Factors (Sox) 2 and 9 in Craniopharyngioma Subtypes and Surrounding Brain Tissue.

Thimsen V, John N, Buchfelder M, Flitsch J, Fahlbusch R, Stefanits H, Knosp E, Losa M, Buslei R, Hölsken A.

Sci Rep. 2017 Nov 20;7(1):15856. doi: 10.1038/s41598-017-15977-3.

28.

Microsurgical therapy of pituitary adenomas.

Mortini P, Barzaghi LR, Albano L, Panni P, Losa M.

Endocrine. 2018 Jan;59(1):72-81. doi: 10.1007/s12020-017-1458-3. Epub 2017 Oct 24.

PMID:
29067608
29.

De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.

Slavotinek A, Risolino M, Losa M, Cho MT, Monaghan KG, Schneidman-Duhovny D, Parisotto S, Herkert JC, Stegmann APA, Miller K, Shur N, Chui J, Muller E, DeBrosse S, Szot JO, Chapman G, Pachter NS, Winlaw DS, Mendelsohn BA, Dalton J, Sarafoglou K, Karachunski PI, Lewis JM, Pedro H, Dunwoodie SL, Selleri L, Shieh J.

Hum Mol Genet. 2017 Dec 15;26(24):4849-4860. doi: 10.1093/hmg/ddx363.

30.

Treatment of empty sella associated with visual impairment: a systematic review of chiasmapexy techniques.

Barzaghi LR, Donofrio CA, Panni P, Losa M, Mortini P.

Pituitary. 2018 Feb;21(1):98-106. doi: 10.1007/s11102-017-0842-6. Review.

PMID:
29027644
31.

A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree.

Losa M, Latorre V, Andrabi M, Ladam F, Sagerström C, Novoa A, Zarrineh P, Bridoux L, Hanley NA, Mallo M, Bobola N.

Elife. 2017 Sep 27;6. pii: e31362. doi: 10.7554/eLife.31362.

32.

Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.

Janouskova H, El Tekle G, Bellini E, Udeshi ND, Rinaldi A, Ulbricht A, Bernasocchi T, Civenni G, Losa M, Svinkina T, Bielski CM, Kryukov GV, Cascione L, Napoli S, Enchev RI, Mutch DG, Carney ME, Berchuck A, Winterhoff BJN, Broaddus RR, Schraml P, Moch H, Bertoni F, Catapano CV, Peter M, Carr SA, Garraway LA, Wild PJ, Theurillat JP.

Nat Med. 2017 Sep;23(9):1046-1054. doi: 10.1038/nm.4372. Epub 2017 Aug 14.

33.

Acromegaly is associated with increased cancer risk: a survey in Italy.

Terzolo M, Reimondo G, Berchialla P, Ferrante E, Malchiodi E, De Marinis L, Pivonello R, Grottoli S, Losa M, Cannavo S, Ferone D, Montini M, Bondanelli M, De Menis E, Martini C, Puxeddu E, Velardo A, Peri A, Faustini-Fustini M, Tita P, Pigliaru F, Peraga G, Borretta G, Scaroni C, Bazzoni N, Bianchi A, Berton A, Serban AL, Baldelli R, Fatti LM, Colao A, Arosio M; Italian Study Group of Acromegaly.

Endocr Relat Cancer. 2017 Sep;24(9):495-504. doi: 10.1530/ERC-16-0553. Epub 2017 Jul 14.

34.

Ovarian hyperstimulation syndrome due to follicle-stimulating hormone-secreting pituitary adenomas.

Caretto A, Lanzi R, Piani C, Molgora M, Mortini P, Losa M.

Pituitary. 2017 Oct;20(5):553-560. doi: 10.1007/s11102-017-0817-7.

PMID:
28676954
35.

Establishment of a protocol to extend the lifespan of human hormone-secreting pituitary adenoma cells.

Aiello A, Cassarino MF, Nanni S, Sesta A, Ferraú F, Grassi C, Losa M, Trimarchi F, Pontecorvi A, Cannavò S, Pecori Giraldi F, Farsetti A.

Endocrine. 2018 Jan;59(1):102-108. doi: 10.1007/s12020-017-1305-6. Epub 2017 Apr 26.

PMID:
28447256
36.

Human papillomavirus and Chlamydia trachomatis infection in gyneco-obstetric outpatients from a mexican hospital.

Conde-Ferráez L, Martíez JR, Ayora-Talavera G, Losa MD.

Indian J Med Microbiol. 2017 Jan-Mar;35(1):74-79. doi: 10.4103/ijmm.IJMM_15_450.

37.

The GIP/GIPR axis is functionally linked to GH-secretion increase in a significant proportion of gsp- somatotropinomas.

Regazzo D, Losa M, Albiger NM, Terreni MR, Vazza G, Ceccato F, Emanuelli E, Denaro L, Scaroni C, Occhi G.

Eur J Endocrinol. 2017 May;176(5):543-553. doi: 10.1530/EJE-16-0831. Epub 2017 Feb 8.

PMID:
28179449
38.
39.

Safety of transsphenoidal microsurgical approach in patients with an ACTH-secreting pituitary adenoma.

Donofrio CA, Losa M, Gemma M, Giudice L, Barzaghi LR, Mortini P.

Endocrine. 2017 Nov;58(2):303-311. doi: 10.1007/s12020-016-1214-0. Epub 2016 Dec 22.

PMID:
28005257
40.

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence.

Revandkar A, Perciato ML, Toso A, Alajati A, Chen J, Gerber H, Dimitrov M, Rinaldi A, Delaleu N, Pasquini E, D'Antuono R, Pinton S, Losa M, Gnetti L, Arribas A, Fraering P, Bertoni F, Nepveu A, Alimonti A.

Nat Commun. 2016 Dec 12;7:13719. doi: 10.1038/ncomms13719.

41.

MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression.

Dallavalle C, Albino D, Civenni G, Merulla J, Ostano P, Mello-Grand M, Rossi S, Losa M, D'Ambrosio G, Sessa F, Thalmann GN, Garcia-Escudero R, Zitella A, Chiorino G, Catapano CV, Carbone GM.

J Clin Invest. 2016 Dec 1;126(12):4585-4602. doi: 10.1172/JCI86505. Epub 2016 Nov 7.

42.

Asymptomatic internal carotid artery occlusion after gamma knife radiosurgery for pituitary adenoma: Report of two cases and review of the literature.

Spatola G, Frosio L, Losa M, Del Vecchio A, Piloni M, Mortini P.

Rep Pract Oncol Radiother. 2016 Nov-Dec;21(6):555-559. Epub 2016 Sep 28.

43.

Frequency, pattern, and outcome of recurrences after gamma knife radiosurgery for pituitary adenomas.

Losa M, Spatola G, Albano L, Gandolfi A, Del Vecchio A, Bolognesi A, Mortini P.

Endocrine. 2017 Jun;56(3):595-602. doi: 10.1007/s12020-016-1081-8. Epub 2016 Sep 29.

PMID:
27688011
44.

Resection of tumors of the third ventricle involving the hypothalamus: effects on body mass index using a dedicated surgical approach.

Mortini P, Gagliardi F, Bailo M, Boari N, Castellano A, Falini A, Losa M.

Endocrine. 2017 Jul;57(1):138-147. doi: 10.1007/s12020-016-1102-7. Epub 2016 Sep 29.

PMID:
27688008
45.

EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke's cleft cysts.

Thimsen V, Hölsken A, Buchfelder M, Flitsch J, Fahlbusch R, Stefanits H, Losa M, Jones DT, Buslei R.

Sci Rep. 2016 Jul 19;6:29731. doi: 10.1038/srep29731.

46.

Proopiomelanocortin, glucocorticoid, and CRH receptor expression in human ACTH-secreting pituitary adenomas.

Cassarino MF, Sesta A, Pagliardini L, Losa M, Lasio G, Cavagnini F, Pecori Giraldi F.

Endocrine. 2017 Mar;55(3):853-860. doi: 10.1007/s12020-016-0990-x. Epub 2016 May 24.

47.

In Vivo Bone Formation Within Engineered Hydroxyapatite Scaffolds in a Sheep Model.

Lovati AB, Lopa S, Recordati C, Talò G, Turrisi C, Bottagisio M, Losa M, Scanziani E, Moretti M.

Calcif Tissue Int. 2016 Aug;99(2):209-23. doi: 10.1007/s00223-016-0140-8. Epub 2016 Apr 13.

PMID:
27075029
48.

Pros and cons in endocrine practice: pre-surgical treatment with somatostatin analogues in acromegaly.

Losa M, Bollerslev J.

Endocrine. 2016 Jun;52(3):451-7. doi: 10.1007/s12020-015-0853-x. Epub 2016 Jan 19.

PMID:
26785848
49.

Suprasellar granular cell tumor of the neurohypophysis: surgical outcome of a very rare tumor.

Gagliardi F, Spina A, Barzaghi LR, Bailo M, Losa M, Terreni MR, Mortini P.

Pituitary. 2016 Jun;19(3):277-85. doi: 10.1007/s11102-016-0704-7.

PMID:
26753850
50.

Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas.

Losa M, Bogazzi F, Cannavo S, Ceccato F, Curtò L, De Marinis L, Iacovazzo D, Lombardi G, Mantovani G, Mazza E, Minniti G, Nizzoli M, Reni M, Scaroni C.

J Neurooncol. 2016 Feb;126(3):519-25. doi: 10.1007/s11060-015-1991-y. Epub 2015 Nov 27.

PMID:
26614517

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