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Items: 1 to 50 of 244

1.

Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas.

Losa M, Mortini P, Pagnano A, Detomas M, Cassarino MF, Pecori Giraldi F.

Endocrine. 2018 Oct 12. doi: 10.1007/s12020-018-1776-0. [Epub ahead of print]

PMID:
30315484
2.

Paradoxical GH increase during OGTT is associated to first-generation somatostatin analogs responsiveness in acromegaly.

Scaroni C, Albiger N, Daniele A, Dassie F, Romualdi C, Vazza G, Regazzo D, Ferraù F, Barresi V, Maffeis V, Gardiman MP, Cannavò S, Maffei P, Ceccato F, Losa M, Occhi G.

J Clin Endocrinol Metab. 2018 Oct 3. doi: 10.1210/jc.2018-01360. [Epub ahead of print]

PMID:
30285115
3.

High Prevalence of Radiological Vertebral Fractures in Patients With TSH-Secreting Pituitary Adenoma.

Frara S, Losa M, Doga M, Formenti AM, Mortini P, Mazziotti G, Giustina A.

J Endocr Soc. 2018 Jul 27;2(9):1089-1099. doi: 10.1210/js.2018-00091. eCollection 2018 Sep 1.

4.

Publisher Correction: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.

Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, de Bono J, Carracedo A, Alimonti A.

Nat Genet. 2018 Sep;50(9):1343. doi: 10.1038/s41588-018-0181-1.

PMID:
30089860
5.

Single fraction and multisession Gamma Knife radiosurgery for craniopharyngioma.

Losa M, Pieri V, Bailo M, Gagliardi F, Barzaghi LR, Gioia L, Del Vecchio A, Bolognesi A, Mortini P.

Pituitary. 2018 Oct;21(5):499-506. doi: 10.1007/s11102-018-0903-5.

PMID:
30043097
6.

IL-23 secreted by myeloid cells drives castration-resistant prostate cancer.

Calcinotto A, Spataro C, Zagato E, Di Mitri D, Gil V, Crespo M, De Bernardis G, Losa M, Mirenda M, Pasquini E, Rinaldi A, Sumanasuriya S, Lambros MB, Neeb A, Lucianò R, Bravi CA, Nava-Rodrigues D, Dolling D, Prayer-Galetti T, Ferreira A, Briganti A, Esposito A, Barry S, Yuan W, Sharp A, de Bono J, Alimonti A.

Nature. 2018 Jul;559(7714):363-369. doi: 10.1038/s41586-018-0266-0. Epub 2018 Jun 27.

PMID:
29950727
7.

Gene expression profiling in human corticotroph tumours reveals distinct, neuroendocrine profiles.

Cassarino MF, Ambrogio AG, Cassarino A, Terreni MR, Gentilini D, Sesta A, Cavagnini F, Losa M, Pecori Giraldi F.

J Neuroendocrinol. 2018 Sep;30(9):e12628. doi: 10.1111/jne.12628. Epub 2018 Aug 7.

8.

PET Evaluation of Late Cerebral Effect in Advanced Radiation Therapy Techniques for Cranial Base Tumors.

Alongi P, Iaccarino L, Losa M, Del Vecchio A, Gerevini S, Plebani V, Di Muzio N, Mortini P, Gianolli L, Perani D.

Curr Radiopharm. 2018;11(2):86-91. doi: 10.2174/1874471011666180525134301.

PMID:
29804540
9.

Pediatric Pituitary Adenomas: Early and Long-Term Surgical Outcome in a Series of 85 Consecutive Patients.

Barzaghi LR, Losa M, Capitanio JF, Albano L, Weber G, Mortini P.

Neurosurgery. 2018 May 22. doi: 10.1093/neuros/nyy204. [Epub ahead of print]

PMID:
29790934
10.

Analysis of characteristics and outcomes by growth hormone treatment duration in adult patients in the Italian cohort of the Hypopituitary Control and Complications Study (HypoCCS).

Rochira V, Mossetto G, Jia N, Cannavo S, Beck-Peccoz P, Aimaretti G, Ambrosio MR, Di Somma C, Losa M, Ferone D, Lubrano C, Scaroni C, Giampietro A, Corsello SM, Poggi M.

J Endocrinol Invest. 2018 Nov;41(11):1259-1266. doi: 10.1007/s40618-018-0860-x. Epub 2018 Mar 13.

11.

Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion.

Losa M, Risolino M, Li B, Hart J, Quintana L, Grishina I, Yang H, Choi IF, Lewicki P, Khan S, Aho R, Feenstra J, Vincent CT, Brown AMC, Ferretti E, Williams T, Selleri L.

Development. 2018 Mar 1;145(5). pii: dev157628. doi: 10.1242/dev.157628.

12.

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.

Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, Bono J, Carracedo A, Alimonti A.

Nat Genet. 2018 Feb;50(2):219-228. doi: 10.1038/s41588-017-0026-3. Epub 2018 Jan 15. Erratum in: Nat Genet. 2018 Sep;50(9):1343.

13.

Expression of SRY-related HMG Box Transcription Factors (Sox) 2 and 9 in Craniopharyngioma Subtypes and Surrounding Brain Tissue.

Thimsen V, John N, Buchfelder M, Flitsch J, Fahlbusch R, Stefanits H, Knosp E, Losa M, Buslei R, Hölsken A.

Sci Rep. 2017 Nov 20;7(1):15856. doi: 10.1038/s41598-017-15977-3.

14.

Microsurgical therapy of pituitary adenomas.

Mortini P, Barzaghi LR, Albano L, Panni P, Losa M.

Endocrine. 2018 Jan;59(1):72-81. doi: 10.1007/s12020-017-1458-3. Epub 2017 Oct 24.

PMID:
29067608
15.

De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.

Slavotinek A, Risolino M, Losa M, Cho MT, Monaghan KG, Schneidman-Duhovny D, Parisotto S, Herkert JC, Stegmann APA, Miller K, Shur N, Chui J, Muller E, DeBrosse S, Szot JO, Chapman G, Pachter NS, Winlaw DS, Mendelsohn BA, Dalton J, Sarafoglou K, Karachunski PI, Lewis JM, Pedro H, Dunwoodie SL, Selleri L, Shieh J.

Hum Mol Genet. 2017 Dec 15;26(24):4849-4860. doi: 10.1093/hmg/ddx363.

PMID:
29036646
16.

Treatment of empty sella associated with visual impairment: a systematic review of chiasmapexy techniques.

Barzaghi LR, Donofrio CA, Panni P, Losa M, Mortini P.

Pituitary. 2018 Feb;21(1):98-106. doi: 10.1007/s11102-017-0842-6. Review.

PMID:
29027644
17.

A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree.

Losa M, Latorre V, Andrabi M, Ladam F, Sagerström C, Novoa A, Zarrineh P, Bridoux L, Hanley NA, Mallo M, Bobola N.

Elife. 2017 Sep 27;6. pii: e31362. doi: 10.7554/eLife.31362.

18.

Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.

Janouskova H, El Tekle G, Bellini E, Udeshi ND, Rinaldi A, Ulbricht A, Bernasocchi T, Civenni G, Losa M, Svinkina T, Bielski CM, Kryukov GV, Cascione L, Napoli S, Enchev RI, Mutch DG, Carney ME, Berchuck A, Winterhoff BJN, Broaddus RR, Schraml P, Moch H, Bertoni F, Catapano CV, Peter M, Carr SA, Garraway LA, Wild PJ, Theurillat JP.

Nat Med. 2017 Sep;23(9):1046-1054. doi: 10.1038/nm.4372. Epub 2017 Aug 14.

19.

Acromegaly is associated with increased cancer risk: a survey in Italy.

Terzolo M, Reimondo G, Berchialla P, Ferrante E, Malchiodi E, De Marinis L, Pivonello R, Grottoli S, Losa M, Cannavo S, Ferone D, Montini M, Bondanelli M, De Menis E, Martini C, Puxeddu E, Velardo A, Peri A, Faustini-Fustini M, Tita P, Pigliaru F, Peraga G, Borretta G, Scaroni C, Bazzoni N, Bianchi A, Berton A, Serban AL, Baldelli R, Fatti LM, Colao A, Arosio M; Italian Study Group of Acromegaly.

Endocr Relat Cancer. 2017 Sep;24(9):495-504. doi: 10.1530/ERC-16-0553. Epub 2017 Jul 14.

20.

Ovarian hyperstimulation syndrome due to follicle-stimulating hormone-secreting pituitary adenomas.

Caretto A, Lanzi R, Piani C, Molgora M, Mortini P, Losa M.

Pituitary. 2017 Oct;20(5):553-560. doi: 10.1007/s11102-017-0817-7.

PMID:
28676954
21.

Establishment of a protocol to extend the lifespan of human hormone-secreting pituitary adenoma cells.

Aiello A, Cassarino MF, Nanni S, Sesta A, Ferraú F, Grassi C, Losa M, Trimarchi F, Pontecorvi A, Cannavò S, Pecori Giraldi F, Farsetti A.

Endocrine. 2018 Jan;59(1):102-108. doi: 10.1007/s12020-017-1305-6. Epub 2017 Apr 26.

PMID:
28447256
22.

Human papillomavirus and Chlamydia trachomatis infection in gyneco-obstetric outpatients from a mexican hospital.

Conde-Ferráez L, Martíez JR, Ayora-Talavera G, Losa MD.

Indian J Med Microbiol. 2017 Jan-Mar;35(1):74-79. doi: 10.4103/ijmm.IJMM_15_450.

23.

The GIP/GIPR axis is functionally linked to GH-secretion increase in a significant proportion of gsp- somatotropinomas.

Regazzo D, Losa M, Albiger NM, Terreni MR, Vazza G, Ceccato F, Emanuelli E, Denaro L, Scaroni C, Occhi G.

Eur J Endocrinol. 2017 May;176(5):543-553. doi: 10.1530/EJE-16-0831. Epub 2017 Feb 8.

PMID:
28179449
24.
25.

Safety of transsphenoidal microsurgical approach in patients with an ACTH-secreting pituitary adenoma.

Donofrio CA, Losa M, Gemma M, Giudice L, Barzaghi LR, Mortini P.

Endocrine. 2017 Nov;58(2):303-311. doi: 10.1007/s12020-016-1214-0. Epub 2016 Dec 22.

PMID:
28005257
26.

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence.

Revandkar A, Perciato ML, Toso A, Alajati A, Chen J, Gerber H, Dimitrov M, Rinaldi A, Delaleu N, Pasquini E, D'Antuono R, Pinton S, Losa M, Gnetti L, Arribas A, Fraering P, Bertoni F, Nepveu A, Alimonti A.

Nat Commun. 2016 Dec 12;7:13719. doi: 10.1038/ncomms13719.

27.

MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression.

Dallavalle C, Albino D, Civenni G, Merulla J, Ostano P, Mello-Grand M, Rossi S, Losa M, D'Ambrosio G, Sessa F, Thalmann GN, Garcia-Escudero R, Zitella A, Chiorino G, Catapano CV, Carbone GM.

J Clin Invest. 2016 Dec 1;126(12):4585-4602. doi: 10.1172/JCI86505. Epub 2016 Nov 7.

28.

Asymptomatic internal carotid artery occlusion after gamma knife radiosurgery for pituitary adenoma: Report of two cases and review of the literature.

Spatola G, Frosio L, Losa M, Del Vecchio A, Piloni M, Mortini P.

Rep Pract Oncol Radiother. 2016 Nov-Dec;21(6):555-559. Epub 2016 Sep 28.

29.

Frequency, pattern, and outcome of recurrences after gamma knife radiosurgery for pituitary adenomas.

Losa M, Spatola G, Albano L, Gandolfi A, Del Vecchio A, Bolognesi A, Mortini P.

Endocrine. 2017 Jun;56(3):595-602. doi: 10.1007/s12020-016-1081-8. Epub 2016 Sep 29.

PMID:
27688011
30.

Resection of tumors of the third ventricle involving the hypothalamus: effects on body mass index using a dedicated surgical approach.

Mortini P, Gagliardi F, Bailo M, Boari N, Castellano A, Falini A, Losa M.

Endocrine. 2017 Jul;57(1):138-147. doi: 10.1007/s12020-016-1102-7. Epub 2016 Sep 29.

PMID:
27688008
31.

EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke's cleft cysts.

Thimsen V, Hölsken A, Buchfelder M, Flitsch J, Fahlbusch R, Stefanits H, Losa M, Jones DT, Buslei R.

Sci Rep. 2016 Jul 19;6:29731. doi: 10.1038/srep29731.

32.

Proopiomelanocortin, glucocorticoid, and CRH receptor expression in human ACTH-secreting pituitary adenomas.

Cassarino MF, Sesta A, Pagliardini L, Losa M, Lasio G, Cavagnini F, Pecori Giraldi F.

Endocrine. 2017 Mar;55(3):853-860. doi: 10.1007/s12020-016-0990-x. Epub 2016 May 24.

33.

In Vivo Bone Formation Within Engineered Hydroxyapatite Scaffolds in a Sheep Model.

Lovati AB, Lopa S, Recordati C, Talò G, Turrisi C, Bottagisio M, Losa M, Scanziani E, Moretti M.

Calcif Tissue Int. 2016 Aug;99(2):209-23. doi: 10.1007/s00223-016-0140-8. Epub 2016 Apr 13.

PMID:
27075029
34.

Pros and cons in endocrine practice: pre-surgical treatment with somatostatin analogues in acromegaly.

Losa M, Bollerslev J.

Endocrine. 2016 Jun;52(3):451-7. doi: 10.1007/s12020-015-0853-x. Epub 2016 Jan 19.

PMID:
26785848
35.

Suprasellar granular cell tumor of the neurohypophysis: surgical outcome of a very rare tumor.

Gagliardi F, Spina A, Barzaghi LR, Bailo M, Losa M, Terreni MR, Mortini P.

Pituitary. 2016 Jun;19(3):277-85. doi: 10.1007/s11102-016-0704-7.

PMID:
26753850
36.

Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas.

Losa M, Bogazzi F, Cannavo S, Ceccato F, Curtò L, De Marinis L, Iacovazzo D, Lombardi G, Mantovani G, Mazza E, Minniti G, Nizzoli M, Reni M, Scaroni C.

J Neurooncol. 2016 Feb;126(3):519-25. doi: 10.1007/s11060-015-1991-y. Epub 2015 Nov 27.

PMID:
26614517
37.

Magnetic resonance imaging as predictor of functional outcome in craniopharyngiomas.

Mortini P, Gagliardi F, Bailo M, Spina A, Parlangeli A, Falini A, Losa M.

Endocrine. 2016 Jan;51(1):148-62. doi: 10.1007/s12020-015-0683-x. Epub 2015 Jul 16.

PMID:
26179178
38.

Characteristics and outcomes of Italian patients from the observational, multicentre, hypopituitary control and complications study (HypoCCS) according to tertiles of growth hormone peak concentration following stimulation testing at study entry.

Losa M, Beck-Peccoz P, Aimaretti G, Di Somma C, Ambrosio MR, Ferone D, Giampietro A, Corsello SM, Poggi M, Scaroni C, Jia N, Mossetto G, Cannavò S, Rochira V.

Clin Endocrinol (Oxf). 2015 Oct;83(4):527-35. doi: 10.1111/cen.12839. Epub 2015 Jul 31.

PMID:
26119712
39.

Is the incidence of differentiated thyroid cancer increased in patients with thyrotropin-secreting adenomas? Report of three cases from a large consecutive series.

Perticone F, Pigliaru F, Mariotti S, Deiana L, Furlani L, Mortini P, Losa M.

Thyroid. 2015 Apr;25(4):417-24. doi: 10.1089/thy.2014.0222. Epub 2015 Mar 9.

PMID:
25647054
40.

Hoxa2 selectively enhances Meis binding to change a branchial arch ground state.

Amin S, Donaldson IJ, Zannino DA, Hensman J, Rattray M, Losa M, Spitz F, Ladam F, Sagerström C, Bobola N.

Dev Cell. 2015 Feb 9;32(3):265-77. doi: 10.1016/j.devcel.2014.12.024. Epub 2015 Jan 29.

41.

Elevated serum creatine kinase after neurosurgeries in lateral position with intraoperative neurophysiological monitoring is associated with OP duration, BMI and age.

Neidert MC, Losa M, Regli L, Sarnthein J.

Clin Neurophysiol. 2015 Oct;126(10):2026-32. doi: 10.1016/j.clinph.2014.12.019. Epub 2015 Jan 14.

PMID:
25631613
42.

Thyrotropin-secreting pituitary adenomas: outcome of pituitary surgery and irradiation.

Malchiodi E, Profka E, Ferrante E, Sala E, Verrua E, Campi I, Lania AG, Arosio M, Locatelli M, Mortini P, Losa M, Motti E, Beck-Peccoz P, Spada A, Mantovani G.

J Clin Endocrinol Metab. 2014 Jun;99(6):2069-76. doi: 10.1210/jc.2013-4376. Epub 2014 Feb 19.

PMID:
24552222
43.

Food intake regulating hormones in adult craniopharyngioma patients.

Roemmler-Zehrer J, Geigenberger V, Störmann S, Losa M, Crippa V, Otto B, Bidlingmaier M, Dimopoulou C, Stalla GK, Schopohl J.

Eur J Endocrinol. 2014 Mar 13;170(4):627-35. doi: 10.1530/EJE-13-0832. Print 2014 Apr.

PMID:
24474740
44.

AZA-deoxycytidine stimulates proopiomelanocortin gene expression and ACTH secretion in human pituitary ACTH-secreting tumors.

Cassarino MF, Sesta A, Pagliardini L, Losa M, Lasio G, Cavagnini F, Pecori Giraldi F.

Pituitary. 2014 Oct;17(5):464-9. doi: 10.1007/s11102-013-0527-8.

PMID:
24085685
45.

Presentation and surgical results of incidentally discovered nonfunctioning pituitary adenomas: evidence for a better outcome independently of other patients' characteristics.

Losa M, Donofrio CA, Barzaghi R, Mortini P.

Eur J Endocrinol. 2013 Oct 21;169(6):735-42. doi: 10.1530/EJE-13-0515. Print 2013 Dec.

PMID:
23999643
46.

Solitary clival plasmocytomas: Misleading clinical and radiological features of a rare pathology with a specific biological behaviour.

Gagliardi F, Losa M, Boari N, Spina A, Reni M, Terreni MR, Mortini P.

Acta Neurochir (Wien). 2013 Oct;155(10):1849-56. doi: 10.1007/s00701-013-1845-3. Epub 2013 Aug 24.

PMID:
23975648
47.

Surgical strategies and modern therapeutic options in the treatment of craniopharyngiomas.

Mortini P, Gagliardi F, Boari N, Losa M.

Crit Rev Oncol Hematol. 2013 Dec;88(3):514-29. doi: 10.1016/j.critrevonc.2013.07.013. Epub 2013 Aug 7. Review.

PMID:
23932582
48.

The Polo-Like Kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia.

Casolaro A, Golay J, Albanese C, Ceruti R, Patton V, Cribioli S, Pezzoni A, Losa M, Texido G, Giussani U, Marchesi F, Amboldi N, Valsasina B, Bungaro S, Cazzaniga G, Rambaldi A, Introna M, Pesenti E, Alzani R.

PLoS One. 2013;8(3):e58424. doi: 10.1371/journal.pone.0058424. Epub 2013 Mar 8.

49.

Suprasellar granular cell tumor of the neurohypophysis in a child: unusual presentation in pediatric age of a rare tumor.

Gagliardi F, Losa M, Boari N, Franzin A, Pozzobon G, Weber G, Mortini P.

Childs Nerv Syst. 2013 Jun;29(6):1031-4. doi: 10.1007/s00381-013-2062-3.

PMID:
23463129
50.

Effects of AMPK activation and combined treatment with AMPK activators and somatostatin on hormone secretion and cell growth in cultured GH-secreting pituitary tumor cells.

Tulipano G, Faggi L, Losa M, Mortini P, Spinello M, Sibilia V, Pagani F, Cocchi D, Giustina A.

Mol Cell Endocrinol. 2013 Jan 30;365(2):197-206. doi: 10.1016/j.mce.2012.10.017. Epub 2012 Oct 29.

PMID:
23116772

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