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Items: 15

1.

Herpesviruses induce aggregation and selective autophagy of host signalling proteins NEMO and RIPK1 as an immune-evasion mechanism.

Muscolino E, Schmitz R, Loroch S, Caragliano E, Schneider C, Rizzato M, Kim YH, Krause E, Juranić Lisnić V, Sickmann A, Reimer R, Ostermann E, Brune W.

Nat Microbiol. 2020 Feb;5(2):331-342. doi: 10.1038/s41564-019-0624-1. Epub 2019 Dec 16.

PMID:
31844296
2.

A sensitive and simple targeted proteomics approach to quantify transcription factor and membrane proteins of the unfolded protein response pathway in glioblastoma cells.

Nguyen CDL, Malchow S, Reich S, Steltgens S, Shuvaev KV, Loroch S, Lorenz C, Sickmann A, Knobbe-Thomsen CB, Tews B, Medenbach J, Ahrends R.

Sci Rep. 2019 Jun 20;9(1):8836. doi: 10.1038/s41598-019-45237-5.

3.

Cannabinoid synthases and osmoprotective metabolites accumulate in the exudates of Cannabis sativa L. glandular trichomes.

Rodziewicz P, Loroch S, Marczak Ł, Sickmann A, Kayser O.

Plant Sci. 2019 Jul;284:108-116. doi: 10.1016/j.plantsci.2019.04.008. Epub 2019 Apr 12.

PMID:
31084863
4.

Activation of E2F-dependent transcription by the mouse cytomegalovirus M117 protein affects the viral host range.

Ostermann E, Loroch S, Qian Z, Sickmann A, Wiebusch L, Brune W.

PLoS Pathog. 2018 Dec 10;14(12):e1007481. doi: 10.1371/journal.ppat.1007481. eCollection 2018 Dec.

5.

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.

Bruning U, Morales-Rodriguez F, Kalucka J, Goveia J, Taverna F, Queiroz KCS, Dubois C, Cantelmo AR, Chen R, Loroch S, Timmerman E, Caixeta V, Bloch K, Conradi LC, Treps L, Staes A, Gevaert K, Tee A, Dewerchin M, Semenkovich CF, Impens F, Schilling B, Verdin E, Swinnen JV, Meier JL, Kulkarni RA, Sickmann A, Ghesquière B, Schoonjans L, Li X, Mazzone M, Carmeliet P.

Cell Metab. 2018 Dec 4;28(6):866-880.e15. doi: 10.1016/j.cmet.2018.07.019. Epub 2018 Aug 23.

6.

Simple, scalable, and ultrasensitive tip-based identification of protease substrates.

Shema G, Nguyen MTN, Solari FA, Loroch S, Venne AS, Kollipara L, Sickmann A, Verhelst SHL, Zahedi RP.

Mol Cell Proteomics. 2018 Apr;17(4):826-834. doi: 10.1074/mcp.TIR117.000302. Epub 2018 Jan 22.

7.

Quantifying Missing (Phospho)Proteome Regions with the Broad-Specificity Protease Subtilisin.

Gonczarowska-Jorge H, Loroch S, Dell'Aica M, Sickmann A, Roos A, Zahedi RP.

Anal Chem. 2017 Dec 19;89(24):13137-13145. doi: 10.1021/acs.analchem.7b02395. Epub 2017 Nov 28.

PMID:
29136377
8.

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.

Di Conza G, Trusso Cafarello S, Loroch S, Mennerich D, Deschoemaeker S, Di Matteo M, Ehling M, Gevaert K, Prenen H, Zahedi RP, Sickmann A, Kietzmann T, Moretti F, Mazzone M.

Cell Rep. 2017 Feb 14;18(7):1699-1712. doi: 10.1016/j.celrep.2017.01.051.

9.

Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B.

Loroch S, Trabold K, Gambaryan S, Reiß C, Schwierczek K, Fleming I, Sickmann A, Behnisch W, Zieger B, Zahedi RP, Walter U, Jurk K.

Thromb Haemost. 2017 Feb 28;117(3):556-569. doi: 10.1160/TH16-07-0515. Epub 2017 Jan 12.

PMID:
28078347
10.

Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition.

Beck F, Geiger J, Gambaryan S, Solari FA, Dell'Aica M, Loroch S, Mattheij NJ, Mindukshev I, Pötz O, Jurk K, Burkhart JM, Fufezan C, Heemskerk JW, Walter U, Zahedi RP, Sickmann A.

Blood. 2017 Jan 12;129(2):e1-e12. doi: 10.1182/blood-2016-05-714048. Epub 2016 Nov 9.

11.

Functional Dissection of an Alternatively Spliced Herpesvirus Gene by Splice Site Mutagenesis.

Schommartz T, Loroch S, Alawi M, Grundhoff A, Sickmann A, Brune W.

J Virol. 2016 Apr 14;90(9):4626-4636. doi: 10.1128/JVI.02987-15. Print 2016 May.

12.

Current strategies and findings in clinically relevant post-translational modification-specific proteomics.

Pagel O, Loroch S, Sickmann A, Zahedi RP.

Expert Rev Proteomics. 2015 Jun;12(3):235-53. doi: 10.1586/14789450.2015.1042867. Epub 2015 May 8. Review.

13.

Multidimensional electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) for quantitative analysis of the proteome and phosphoproteome in clinical and biomedical research.

Loroch S, Schommartz T, Brune W, Zahedi RP, Sickmann A.

Biochim Biophys Acta. 2015 May;1854(5):460-8. doi: 10.1016/j.bbapap.2015.01.006. Epub 2015 Jan 22.

PMID:
25619855
14.

Highly sensitive phosphoproteomics by tailoring solid-phase extraction to electrostatic repulsion-hydrophilic interaction chromatography.

Loroch S, Zahedi RP, Sickmann A.

Anal Chem. 2015 Feb 3;87(3):1596-604. doi: 10.1021/ac502708m. Epub 2015 Jan 13.

PMID:
25405705
15.

Phosphoproteomics--more than meets the eye.

Loroch S, Dickhut C, Zahedi RP, Sickmann A.

Electrophoresis. 2013 Jun;34(11):1483-92. doi: 10.1002/elps.201200710. Epub 2013 May 14. Review.

PMID:
23576030

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