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Items: 46

1.

Antifungal Activity of the Enterococcus faecalis Peptide EntV Requires Protease Cleavage and Disulfide Bond Formation.

Brown AO, Graham CE, Cruz MR, Singh KV, Murray BE, Lorenz MC, Garsin DA.

MBio. 2019 Jul 2;10(4). pii: e01334-19. doi: 10.1128/mBio.01334-19.

2.

N-Acetylglucosamine Metabolism Promotes Survival of Candida albicans in the Phagosome.

Vesely EM, Williams RB, Konopka JB, Lorenz MC.

mSphere. 2017 Sep 6;2(5). pii: e00357-17. doi: 10.1128/mSphere.00357-17. eCollection 2017 Sep-Oct.

3.

Enterococcus faecalis bacteriocin EntV inhibits hyphal morphogenesis, biofilm formation, and virulence of Candida albicans.

Graham CE, Cruz MR, Garsin DA, Lorenz MC.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4507-4512. doi: 10.1073/pnas.1620432114. Epub 2017 Apr 10.

4.

A feast for Candida: Metabolic plasticity confers an edge for virulence.

Miramón P, Lorenz MC.

PLoS Pathog. 2017 Feb 9;13(2):e1006144. doi: 10.1371/journal.ppat.1006144. eCollection 2017 Feb. Review. No abstract available.

5.

Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids.

Danhof HA, Vylkova S, Vesely EM, Ford AE, Gonzalez-Garay M, Lorenz MC.

MBio. 2016 Nov 15;7(6). pii: e01646-16. doi: 10.1128/mBio.01646-16.

6.

Phagosomal Neutralization by the Fungal Pathogen Candida albicans Induces Macrophage Pyroptosis.

Vylkova S, Lorenz MC.

Infect Immun. 2017 Jan 26;85(2). pii: e00832-16. doi: 10.1128/IAI.00832-16. Print 2017 Feb.

7.

The SPS amino acid sensor mediates nutrient acquisition and immune evasion in Candida albicans.

Miramón P, Lorenz MC.

Cell Microbiol. 2016 Nov;18(11):1611-1624. doi: 10.1111/cmi.12600. Epub 2016 May 27.

8.

The Candida albicans ATO Gene Family Promotes Neutralization of the Macrophage Phagolysosome.

Danhof HA, Lorenz MC.

Infect Immun. 2015 Nov;83(11):4416-26. doi: 10.1128/IAI.00984-15. Epub 2015 Sep 8.

9.

Characterization of Virulence-Related Phenotypes in Candida Species of the CUG Clade.

Priest SJ, Lorenz MC.

Eukaryot Cell. 2015 Sep;14(9):931-40. doi: 10.1128/EC.00062-15. Epub 2015 Jul 6.

10.

Candida albicans suppresses nitric oxide generation from macrophages via a secreted molecule.

Collette JR, Zhou H, Lorenz MC.

PLoS One. 2014 Apr 22;9(4):e96203. doi: 10.1371/journal.pone.0096203. eCollection 2014.

11.

Modulation of phagosomal pH by Candida albicans promotes hyphal morphogenesis and requires Stp2p, a regulator of amino acid transport.

Vylkova S, Lorenz MC.

PLoS Pathog. 2014 Mar 13;10(3):e1003995. doi: 10.1371/journal.ppat.1003995. eCollection 2014 Mar.

12.

Fungal immune evasion in a model host-pathogen interaction: Candida albicans versus macrophages.

Jiménez-López C, Lorenz MC.

PLoS Pathog. 2013;9(11):e1003741. doi: 10.1371/journal.ppat.1003741. Epub 2013 Nov 21. Review. No abstract available.

13.

Candida albicans and Enterococcus faecalis in the gut: synergy in commensalism?

Garsin DA, Lorenz MC.

Gut Microbes. 2013 Sep-Oct;4(5):409-15. doi: 10.4161/gmic.26040. Epub 2013 Aug 14.

14.

Alternative splicing and subfunctionalization generates functional diversity in fungal proteomes.

Marshall AN, Montealegre MC, Jiménez-López C, Lorenz MC, van Hoof A.

PLoS Genet. 2013;9(3):e1003376. doi: 10.1371/journal.pgen.1003376. Epub 2013 Mar 14.

15.

Carbon catabolite control in Candida albicans: new wrinkles in metabolism.

Lorenz MC.

MBio. 2013 Feb 5;4(1):e00034-13. doi: 10.1128/mBio.00034-13.

16.

The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection.

Jain C, Pastor K, Gonzalez AY, Lorenz MC, Rao RP.

Virulence. 2013 Jan 1;4(1):67-76. doi: 10.4161/viru.22700.

17.

Candida albicans induces arginine biosynthetic genes in response to host-derived reactive oxygen species.

Jiménez-López C, Collette JR, Brothers KM, Shepardson KM, Cramer RA, Wheeler RT, Lorenz MC.

Eukaryot Cell. 2013 Jan;12(1):91-100. doi: 10.1128/EC.00290-12. Epub 2012 Nov 9.

18.

Enterococcus faecalis inhibits hyphal morphogenesis and virulence of Candida albicans.

Cruz MR, Graham CE, Gagliano BC, Lorenz MC, Garsin DA.

Infect Immun. 2013 Jan;81(1):189-200. doi: 10.1128/IAI.00914-12. Epub 2012 Oct 31.

19.

A potent plant-derived antifungal acetylenic acid mediates its activity by interfering with fatty acid homeostasis.

Xu T, Tripathi SK, Feng Q, Lorenz MC, Wright MA, Jacob MR, Mask MM, Baerson SR, Li XC, Clark AM, Agarwal AK.

Antimicrob Agents Chemother. 2012 Jun;56(6):2894-907. doi: 10.1128/AAC.05663-11. Epub 2012 Mar 19.

20.

The bZIP transcription factor Rca1p is a central regulator of a novel CO₂ sensing pathway in yeast.

Cottier F, Raymond M, Kurzai O, Bolstad M, Leewattanapasuk W, Jiménez-López C, Lorenz MC, Sanglard D, Váchová L, Pavelka N, Palková Z, Mühlschlegel FA.

PLoS Pathog. 2012 Jan;8(1):e1002485. doi: 10.1371/journal.ppat.1002485. Epub 2012 Jan 12.

21.

Mechanisms of immune evasion in fungal pathogens.

Collette JR, Lorenz MC.

Curr Opin Microbiol. 2011 Dec;14(6):668-75. doi: 10.1016/j.mib.2011.09.007. Epub 2011 Sep 28. Review.

PMID:
21955887
22.

The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH.

Vylkova S, Carman AJ, Danhof HA, Collette JR, Zhou H, Lorenz MC.

MBio. 2011 May 17;2(3):e00055-11. doi: 10.1128/mBio.00055-11. Print 2011.

23.

Host-microbe interactions: fungi.

Lorenz MC.

Curr Opin Microbiol. 2010 Aug;13(4):389-91. doi: 10.1016/j.mib.2010.05.010. Epub 2010 Jun 16. No abstract available.

24.

The transcription factor homolog CTF1 regulates {beta}-oxidation in Candida albicans.

Ramírez MA, Lorenz MC.

Eukaryot Cell. 2009 Oct;8(10):1604-14. doi: 10.1128/EC.00206-09. Epub 2009 Aug 21.

25.

Morphogenic and genetic differences between Candida albicans strains are associated with keratomycosis virulence.

Hua X, Yuan X, Mitchell BM, Lorenz MC, O'Day DM, Wilhelmus KR.

Mol Vis. 2009 Jul 30;15:1476-84.

26.

Evolution of pathogenicity and sexual reproduction in eight Candida genomes.

Butler G, Rasmussen MD, Lin MF, Santos MA, Sakthikumar S, Munro CA, Rheinbay E, Grabherr M, Forche A, Reedy JL, Agrafioti I, Arnaud MB, Bates S, Brown AJ, Brunke S, Costanzo MC, Fitzpatrick DA, de Groot PW, Harris D, Hoyer LL, Hube B, Klis FM, Kodira C, Lennard N, Logue ME, Martin R, Neiman AM, Nikolaou E, Quail MA, Quinn J, Santos MC, Schmitzberger FF, Sherlock G, Shah P, Silverstein KA, Skrzypek MS, Soll D, Staggs R, Stansfield I, Stumpf MP, Sudbery PE, Srikantha T, Zeng Q, Berman J, Berriman M, Heitman J, Gow NA, Lorenz MC, Birren BW, Kellis M, Cuomo CA.

Nature. 2009 Jun 4;459(7247):657-62. doi: 10.1038/nature08064.

27.

Role of acetyl coenzyme A synthesis and breakdown in alternative carbon source utilization in Candida albicans.

Carman AJ, Vylkova S, Lorenz MC.

Eukaryot Cell. 2008 Oct;7(10):1733-41. doi: 10.1128/EC.00253-08. Epub 2008 Aug 8.

28.

Carnitine acetyltransferases are required for growth on non-fermentable carbon sources but not for pathogenesis in Candida albicans.

Zhou H, Lorenz MC.

Microbiology. 2008 Feb;154(Pt 2):500-9. doi: 10.1099/mic.0.2007/014555-0.

PMID:
18227254
29.

Role of heme in the antifungal activity of the azaoxoaporphine alkaloid sampangine.

Agarwal AK, Xu T, Jacob MR, Feng Q, Lorenz MC, Walker LA, Clark AM.

Eukaryot Cell. 2008 Feb;7(2):387-400. Epub 2007 Dec 21.

30.

CTA4 transcription factor mediates induction of nitrosative stress response in Candida albicans.

Chiranand W, McLeod I, Zhou H, Lynn JJ, Vega LA, Myers H, Yates JR 3rd, Lorenz MC, Gustin MC.

Eukaryot Cell. 2008 Feb;7(2):268-78. Epub 2007 Dec 14.

31.

Cerebrovascular responses to incremental exercise during hypobaric hypoxia: effect of oxygenation on maximal performance.

Subudhi AW, Lorenz MC, Fulco CS, Roach RC.

Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H164-71. Epub 2007 Nov 21.

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34.

Transcriptional response of Candida albicans upon internalization by macrophages.

Lorenz MC, Bender JA, Fink GR.

Eukaryot Cell. 2004 Oct;3(5):1076-87.

35.

Life and death in a macrophage: role of the glyoxylate cycle in virulence.

Lorenz MC, Fink GR.

Eukaryot Cell. 2002 Oct;1(5):657-62. Review. No abstract available.

36.

Genomic approaches to fungal pathogenicity.

Lorenz MC.

Curr Opin Microbiol. 2002 Aug;5(4):372-8. Review.

PMID:
12160855
37.

The glyoxylate cycle is required for fungal virulence.

Lorenz MC, Fink GR.

Nature. 2001 Jul 5;412(6842):83-6.

PMID:
11452311
38.
39.

The G protein-coupled receptor gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae.

Lorenz MC, Pan X, Harashima T, Cardenas ME, Xue Y, Hirsch JP, Heitman J.

Genetics. 2000 Feb;154(2):609-22.

40.

Characterization of alcohol-induced filamentous growth in Saccharomyces cerevisiae.

Lorenz MC, Cutler NS, Heitman J.

Mol Biol Cell. 2000 Jan;11(1):183-99.

41.

The TOR signaling cascade regulates gene expression in response to nutrients.

Cardenas ME, Cutler NS, Lorenz MC, Di Como CJ, Heitman J.

Genes Dev. 1999 Dec 15;13(24):3271-9.

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46.

Gene disruption with PCR products in Saccharomyces cerevisiae.

Lorenz MC, Muir RS, Lim E, McElver J, Weber SC, Heitman J.

Gene. 1995 May 26;158(1):113-7.

PMID:
7789793

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