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Items: 1 to 50 of 91

1.

Moving proteins along in the cilium.

Petriman NA, Lorentzen E.

Elife. 2020 Feb 13;9. pii: e55254. doi: 10.7554/eLife.55254.

2.

Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor.

Lorentzen EM, Henriksen S, Kaur A, Kro GB, Hammarström C, Hirsch HH, Midtvedt K, Rinaldo CH.

Virol J. 2020 Jan 10;17(1):5. doi: 10.1186/s12985-019-1275-9.

3.

APOE ε4 is associated with younger age at ischemic stroke onset but not with stroke outcome.

Lagging C, Lorentzen E, Stanne TM, Pedersen A, Söderholm M, Cole JW, Jood K, Lemmens R, Phuah CL, Rost NS, Thijs V, Woo D, Maguire JM, Lindgren A, Jern C; Genetics of Ischaemic Stroke Functional Outcome (GISCOME) network and the International Stroke Genetics Consortium.

Neurology. 2019 Nov 5;93(19):849-853. doi: 10.1212/WNL.0000000000008459. Epub 2019 Oct 16. No abstract available.

4.

Homeostatic Chemokines and Prognosis in Patients With Acute Coronary Syndromes.

Caidahl K, Hartford M, Ravn-Fischer A, Lorentzen E, Yndestad A, Karlsson T, Aukrust P, Ueland T.

J Am Coll Cardiol. 2019 Aug 13;74(6):774-782. doi: 10.1016/j.jacc.2019.06.030.

PMID:
31395128
5.

Genetically Determined Risk of Depression and Functional Outcome After Ischemic Stroke.

Gill D, James NE, Monori G, Lorentzen E, Fernandez-Cadenas I, Lemmens R, Thijs V, Rost NS, Scott R, Hankey GJ, Lindgren A, Jern C, Maguire JM; International Stroke Genetics Consortium and the GISCOME Network.

Stroke. 2019 Aug;50(8):2219-2222. doi: 10.1161/STROKEAHA.119.026089. Epub 2019 Jun 26.

6.

Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.

Walia V, Cuenca A, Vetter M, Insinna C, Perera S, Lu Q, Ritt DA, Semler E, Specht S, Stauffer J, Morrison DK, Lorentzen E, Westlake CJ.

Dev Cell. 2019 Jul 22;50(2):229-246.e7. doi: 10.1016/j.devcel.2019.05.022. Epub 2019 Jun 13.

PMID:
31204173
7.

Big Data Approaches to Phenotyping Acute Ischemic Stroke Using Automated Lesion Segmentation of Multi-Center Magnetic Resonance Imaging Data.

Wu O, Winzeck S, Giese AK, Hancock BL, Etherton MR, Bouts MJRJ, Donahue K, Schirmer MD, Irie RE, Mocking SJT, McIntosh EC, Bezerra R, Kamnitsas K, Frid P, Wasselius J, Cole JW, Xu H, Holmegaard L, Jiménez-Conde J, Lemmens R, Lorentzen E, McArdle PF, Meschia JF, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Stanne TM, Thijs V, Vagal A, Woo D, Bevan S, Kittner SJ, Mitchell BD, Rosand J, Worrall BB, Jern C, Lindgren AG, Maguire J, Rost NS.

Stroke. 2019 Jul;50(7):1734-1741. doi: 10.1161/STROKEAHA.119.025373. Epub 2019 Jun 10.

PMID:
31177973
8.

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M.

Nat Genet. 2019 Jul;51(7):1192-1193. doi: 10.1038/s41588-019-0449-0.

9.

The ins and outs of the Arf4-based ciliary membrane-targeting complex.

Deretic D, Lorentzen E, Fresquez T.

Small GTPases. 2019 May 9:1-12. doi: 10.1080/21541248.2019.1616355. [Epub ahead of print]

PMID:
31068062
10.

Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion.

Dupont MA, Humbert C, Huber C, Siour Q, Guerrera IC, Jung V, Christensen A, Pouliet A, Garfa-Traoré M, Nitschké P, Injeyan M, Millar K, Chitayat D, Shannon P, Girisha KM, Shukla A, Mechler C, Lorentzen E, Benmerah A, Cormier-Daire V, Jeanpierre C, Saunier S, Delous M.

Hum Mol Genet. 2019 Aug 15;28(16):2720-2737. doi: 10.1093/hmg/ddz091.

PMID:
31042281
11.

Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly.

Wachter S, Jung J, Shafiq S, Basquin J, Fort C, Bastin P, Lorentzen E.

EMBO J. 2019 May 2;38(9). pii: e101251. doi: 10.15252/embj.2018101251. Epub 2019 Apr 2.

PMID:
30940671
12.

Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.

Bachmaier S, Volpato Santos Y, Kramer S, Githure GB, Klöckner T, Pepperl J, Baums C, Schenk R, Schwede F, Genieser HG, Dupuy JW, Forné I, Imhof A, Basquin J, Lorentzen E, Boshart M.

Nat Commun. 2019 Mar 29;10(1):1421. doi: 10.1038/s41467-019-09338-z.

13.

Genome-wide association meta-analysis of functional outcome after ischemic stroke.

Söderholm M, Pedersen A, Lorentzen E, Stanne TM, Bevan S, Olsson M, Cole JW, Fernandez-Cadenas I, Hankey GJ, Jimenez-Conde J, Jood K, Lee JM, Lemmens R, Levi C, Mitchell BD, Norrving B, Rannikmäe K, Rost NS, Rosand J, Rothwell PM, Scott R, Strbian D, Sturm JW, Sudlow C, Traylor M, Thijs V, Tatlisumak T, Woo D, Worrall BB, Maguire JM, Lindgren A, Jern C; International Stroke Genetics Consortium, the NINDS-SiGN Consortium, and the Genetics of Ischaemic Stroke Functional Outcome (GISCOME) Network.

Neurology. 2019 Mar 19;92(12):e1271-e1283. doi: 10.1212/WNL.0000000000007138. Epub 2019 Feb 22.

14.

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome.

Mola-Caminal M, Carrera C, Soriano-Tárraga C, Giralt-Steinhauer E, Díaz-Navarro RM, Tur S, Jiménez C, Medina-Dols A, Cullell N, Torres-Aguila NP, Muiño E, Rodríguez-Campello A, Ois A, Cuadrado-Godia E, Vivanco-Hidalgo RM, Hernandez-Guillamon M, Solé M, Delgado P, Bustamante A, García-Berrocoso T, Mendióroz M, Castellanos M, Serena J, Martí-Fàbregas J, Segura T, Serrano-Heras G, Obach V, Ribó M, Molina CA, Alvarez-Sabín J, Palomeras E, Freijo M, Font MA, Rosand J, Rost NS, Gallego-Fabrega C, Lee JM, Heitsch L, Ibanez L, Cruchaga C, Phuah CL, Lemmens R, Thijs V, Lindgren A, Maguire J, Rannikmae K, Sudlow CL, Jern C, Stanne TM, Lorentzen E, Muñoz-Narbona L, Dávalos A, López-Cancio E, Worrall BB, Woo D, Kittner SJ, Mitchell BD, Montaner J, Roquer J, Krupinski J, Estivill X, Rabionet R, Vives-Bauzá C, Fernández-Cadenas I, Jiménez-Conde J.

Circ Res. 2019 Jan 4;124(1):114-120. doi: 10.1161/CIRCRESAHA.118.313533.

15.

Membrane association and remodeling by intraflagellar transport protein IFT172.

Wang Q, Taschner M, Ganzinger KA, Kelley C, Villasenor A, Heymann M, Schwille P, Lorentzen E, Mizuno N.

Nat Commun. 2018 Nov 8;9(1):4684. doi: 10.1038/s41467-018-07037-9.

16.

Trafficking of ciliary membrane proteins by the intraflagellar transport/BBSome machinery.

Wingfield JL, Lechtreck KF, Lorentzen E.

Essays Biochem. 2018 Dec 7;62(6):753-763. doi: 10.1042/EBC20180030. Print 2018 Dec 7. Review.

17.

Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity.

Olsson M, Stanne TM, Pedersen A, Lorentzen E, Kara E, Martinez-Palacian A, Rønnow Sand NP, Jacobsen AF, Sandset PM, Sidelmann JJ, Engström G, Melander O, Kanse SM, Jern C.

J Thromb Haemost. 2018 Oct;16(10):2024-2034. doi: 10.1111/jth.14258. Epub 2018 Aug 24.

18.

Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis.

Taschner M, Lorentzen A, Mourão A, Collins T, Freke GM, Moulding D, Basquin J, Jenkins D, Lorentzen E.

Elife. 2018 Apr 16;7. pii: e33067. doi: 10.7554/eLife.33067.

19.

Serum neutrophil gelatinase-associated lipocalin (NGAL) concentration is independently associated with mortality in patients with acute coronary syndrome.

Nymo SH, Hartford M, Ueland T, Yndestad A, Lorentzen E, Truvé K, Karlsson T, Ravn-Fischer A, Aukrust P, Caidahl K.

Int J Cardiol. 2018 Jul 1;262:79-84. doi: 10.1016/j.ijcard.2018.03.028. Epub 2018 Mar 8.

PMID:
29622507
20.

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia.

Chen X, Gustafsson S, Whitington T, Borné Y, Lorentzen E, Sun J, Almgren P, Su J, Karlsson R, Song J, Lu Y, Zhan Y, Hägg S, Svensson P, Smedby KE, Slager SL, Ingelsson E, Lindgren CM, Morris AP, Melander O, Karlsson T, de Faire U, Caidahl K, Engström G, Lind L, Karlsson MCI, Pedersen NL, Frostegård J, Magnusson PKE.

Hum Mol Genet. 2018 May 15;27(10):1809-1818. doi: 10.1093/hmg/ddy094.

PMID:
29547969
21.

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M.

Nat Genet. 2018 Apr;50(4):524-537. doi: 10.1038/s41588-018-0058-3. Epub 2018 Mar 12. Erratum in: Nat Genet. 2019 Jul;51(7):1192-1193.

22.

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor.

Stanne TM, Olsson M, Lorentzen E, Pedersen A, Gummesson A, Gils A, Jood K, Engström G, Melander O, Declerck PJ, Jern C.

Thromb Haemost. 2018 Feb;118(2):298-308. doi: 10.1160/TH17-04-0249. Epub 2018 Jan 29.

23.

Crystal structure of tetrameric human Rabin8 GEF domain.

Vetter M, Boegholm N, Christensen A, Bhogaraju S, Andersen MB, Lorentzen A, Lorentzen E.

Proteins. 2018 Apr;86(4):405-413. doi: 10.1002/prot.25455. Epub 2018 Jan 29.

PMID:
29318657
24.

IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.

Taulet N, Vitre B, Anguille C, Douanier A, Rocancourt M, Taschner M, Lorentzen E, Echard A, Delaval B.

Nat Commun. 2017 Dec 4;8(1):1928. doi: 10.1038/s41467-017-01479-3.

25.

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

Steger M, Diez F, Dhekne HS, Lis P, Nirujogi RS, Karayel O, Tonelli F, Martinez TN, Lorentzen E, Pfeffer SR, Alessi DR, Mann M.

Elife. 2017 Nov 10;6. pii: e31012. doi: 10.7554/eLife.31012.

26.

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis.

Eriksson J, Haring R, Grarup N, Vandenput L, Wallaschofski H, Lorentzen E, Hansen T, Mellström D, Pedersen O, Nauck M, Lorentzon M, Nystrup Husemoen LL, Völzke H, Karlsson M, Baumeister SE, Linneberg A, Ohlsson C.

PLoS One. 2017 Apr 27;12(4):e0176277. doi: 10.1371/journal.pone.0176277. eCollection 2017.

27.

Intraflagellar transport protein IFT52 recruits IFT46 to the basal body and flagella.

Lv B, Wan L, Taschner M, Cheng X, Lorentzen E, Huang K.

J Cell Sci. 2017 May 1;130(9):1662-1674. doi: 10.1242/jcs.200758. Epub 2017 Mar 16.

28.

Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46.

Taschner M, Mourão A, Awasthi M, Basquin J, Lorentzen E.

J Biol Chem. 2017 May 5;292(18):7462-7473. doi: 10.1074/jbc.M117.780155. Epub 2017 Mar 15.

29.

Enhanced viral clearance and reduced leukocyte infiltration in experimental herpes encephalitis after intranasal infection of CXCR3-deficient mice.

Zimmermann J, Hafezi W, Dockhorn A, Lorentzen EU, Krauthausen M, Getts DR, Müller M, Kühn JE, King NJC.

J Neurovirol. 2017 Jun;23(3):394-403. doi: 10.1007/s13365-016-0508-6. Epub 2017 Jan 23.

PMID:
28116674
30.

Corrigendum to "The intraflagellar transport machinery in ciliary signaling" [Curr Opin Struct Biol 2016, 41:98-108].

Mourão A, Christensen ST, Lorentzen E.

Curr Opin Struct Biol. 2016 Dec;41:255. doi: 10.1016/j.sbi.2016.07.018. Epub 2016 Aug 18. No abstract available.

PMID:
27546002
31.

Recombinant Reconstitution and Purification of the IFT-B Core Complex from Chlamydomonas reinhardtii.

Taschner M, Lorentzen E.

Methods Mol Biol. 2016;1454:69-82. doi: 10.1007/978-1-4939-3789-9_5.

PMID:
27514916
32.

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Jakobsdottir J, Wassel C, Register TC, Oei L, Alonso N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L, Terry G, Cox AJ, Allison MA, Criqui MH, Bowden D, Ikram MA, Mellström D, Karlsson MK, Carr J, Budoff M, Phillips C, Cupples LA, Chou WC, Myers RH, Ralston SH, Gautvik KM, Cawthon PM, Cummings S, Karasik D, Rivadeneira F, Gudnason V, Orwoll ES, Harris TB, Ohlsson C, Kiel DP, Hsu YH.

J Bone Miner Res. 2016 Dec;31(12):2085-2097. doi: 10.1002/jbmr.2913. Epub 2016 Sep 6.

33.

Exome array analysis of ischaemic stroke: results from a southern Swedish study.

Söderholm M, Almgren P, Jood K, Stanne TM, Olsson M, Ilinca A, Lorentzen E, Norrving B, Engström G, Melander O, Jern C, Lindgren A.

Eur J Neurol. 2016 Dec;23(12):1722-1728. doi: 10.1111/ene.13086. Epub 2016 Jul 29.

PMID:
27469034
34.

The intraflagellar transport machinery in ciliary signaling.

Mourão A, Christensen ST, Lorentzen E.

Curr Opin Struct Biol. 2016 Dec;41:98-108. doi: 10.1016/j.sbi.2016.06.009. Epub 2016 Jul 6. Review. Erratum in: Curr Opin Struct Biol. 2016 Dec;41:255.

PMID:
27393972
35.

The Intraflagellar Transport Machinery.

Taschner M, Lorentzen E.

Cold Spring Harb Perspect Biol. 2016 Oct 3;8(10). pii: a028092. doi: 10.1101/cshperspect.a028092. Review.

36.

Complex Reconstitution from Individual Protein Modules.

Basquin J, Taschner M, Lorentzen E.

Adv Exp Med Biol. 2016;896:305-14. doi: 10.1007/978-3-319-27216-0_19. Review.

PMID:
27165333
37.

Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.

Taschner M, Weber K, Mourão A, Vetter M, Awasthi M, Stiegler M, Bhogaraju S, Lorentzen E.

EMBO J. 2016 Apr 1;35(7):773-90. doi: 10.15252/embj.201593164. Epub 2016 Feb 24.

38.

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

Steger M, Tonelli F, Ito G, Davies P, Trost M, Vetter M, Wachter S, Lorentzen E, Duddy G, Wilson S, Baptista MA, Fiske BK, Fell MJ, Morrow JA, Reith AD, Alessi DR, Mann M.

Elife. 2016 Jan 29;5. pii: e12813. doi: 10.7554/eLife.12813.

39.

Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.

Bizet AA, Becker-Heck A, Ryan R, Weber K, Filhol E, Krug P, Halbritter J, Delous M, Lasbennes MC, Linghu B, Oakeley EJ, Zarhrate M, Nitschké P, Garfa-Traore M, Serluca F, Yang F, Bouwmeester T, Pinson L, Cassuto E, Dubot P, Elshakhs NAS, Sahel JA, Salomon R, Drummond IA, Gubler MC, Antignac C, Chibout S, Szustakowski JD, Hildebrandt F, Lorentzen E, Sailer AW, Benmerah A, Saint-Mezard P, Saunier S.

Nat Commun. 2015 Oct 21;6:8666. doi: 10.1038/ncomms9666.

40.

Novel topography of the Rab11-effector interaction network within a ciliary membrane targeting complex.

Vetter M, Wang J, Lorentzen E, Deretic D.

Small GTPases. 2015 Oct 2;6(4):165-73. doi: 10.1080/21541248.2015.1091539. Epub 2015 Sep 23. Review.

41.

IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype.

Perrault I, Halbritter J, Porath JD, Gérard X, Braun DA, Gee HY, Fathy HM, Saunier S, Cormier-Daire V, Thomas S, Attié-Bitach T, Boddaert N, Taschner M, Schueler M, Lorentzen E, Lifton RP, Lawson JA, Garfa-Traore M, Otto EA, Bastin P, Caillaud C, Kaplan J, Rozet JM, Hildebrandt F.

J Med Genet. 2015 Oct;52(10):657-65. doi: 10.1136/jmedgenet-2014-102838. Epub 2015 Aug 14.

42.

Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11.

Vetter M, Stehle R, Basquin C, Lorentzen E.

Nat Struct Mol Biol. 2015 Sep;22(9):695-702. doi: 10.1038/nsmb.3065. Epub 2015 Aug 10.

PMID:
26258637
43.

Cutaneous RANK-RANKL Signaling Upregulates CD8-Mediated Antiviral Immunity during Herpes simplex Virus Infection by Preventing Virus-Induced Langerhans Cell Apoptosis.

Klenner L, Hafezi W, Clausen BE, Lorentzen EU, Luger TA, Beissert S, Kühn JE, Loser K.

J Invest Dermatol. 2015 Nov;135(11):2676-2687. doi: 10.1038/jid.2015.225. Epub 2015 Jun 15.

44.

Structural basis for membrane targeting of the BBSome by ARL6.

Mourão A, Nager AR, Nachury MV, Lorentzen E.

Nat Struct Mol Biol. 2014 Dec;21(12):1035-41. doi: 10.1038/nsmb.2920. Epub 2014 Nov 17.

45.

Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly.

Taschner M, Kotsis F, Braeuer P, Kuehn EW, Lorentzen E.

J Cell Biol. 2014 Oct 27;207(2):269-82. doi: 10.1083/jcb.201408002.

46.

Crystal structure of a Chlamydomonas reinhardtii flagellar RabGAP TBC-domain at 1.8 Å resolution.

Bhogaraju S, Lorentzen E.

Proteins. 2014 Sep;82(9):2282-7. doi: 10.1002/prot.24597. Epub 2014 May 17.

PMID:
24810373
47.

Getting tubulin to the tip of the cilium: one IFT train, many different tubulin cargo-binding sites?

Bhogaraju S, Weber K, Engel BD, Lechtreck KF, Lorentzen E.

Bioessays. 2014 May;36(5):463-7. doi: 10.1002/bies.201400007. Epub 2014 Mar 10.

PMID:
24616010
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Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.

Bhogaraju S, Cajanek L, Fort C, Blisnick T, Weber K, Taschner M, Mizuno N, Lamla S, Bastin P, Nigg EA, Lorentzen E.

Science. 2013 Aug 30;341(6149):1009-12. doi: 10.1126/science.1240985.

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Intraflagellar transport complex structure and cargo interactions.

Bhogaraju S, Engel BD, Lorentzen E.

Cilia. 2013 Aug 14;2(1):10. doi: 10.1186/2046-2530-2-10.

50.

Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 Å resolution.

Taschner M, Basquin J, Benda C, Lorentzen E.

Proteins. 2013 Aug;81(8):1473-8. doi: 10.1002/prot.24296. Epub 2013 Jun 1.

PMID:
23553965

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