Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 87

1.

Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect.

Sharma S, Xue Y, Xing Z, Yassin MA, Sun Y, Lorens JB, Finne-Wistrand A, Sapkota D, Mustafa K.

Bone Rep. 2019 Apr 11;10:100205. doi: 10.1016/j.bonr.2019.100205. eCollection 2019 Jun.

2.

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.

Røsland GV, Dyrstad SE, Tusubira D, Helwa R, Tan TZ, Lotsberg ML, Pettersen IKN, Berg A, Kindt C, Hoel F, Jacobsen K, Arason AJ, Engelsen AST, Ditzel HJ, Lønning PE, Krakstad C, Thiery JP, Lorens JB, Knappskog S, Tronstad KJ.

Cancer Metab. 2019 Jun 1;7:6. doi: 10.1186/s40170-019-0197-8. eCollection 2019.

3.

AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction.

Landolt L, Furriol J, Babickova J, Ahmed L, Eikrem Ø, Skogstrand T, Scherer A, Suliman S, Leh S, Lorens JB, Gausdal G, Marti HP, Osman T.

Physiol Rep. 2019 May;7(10):e14091. doi: 10.14814/phy2.14091.

4.

Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT-β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2.

Poirier M, Awale M, Roelli MA, Giuffredi GT, Ruddigkeit L, Evensen L, Stooss A, Calarco S, Lorens JB, Charles RP, Reymond JL.

ChemMedChem. 2019 Jan 22;14(2):224-236. doi: 10.1002/cmdc.201800554. Epub 2018 Dec 6.

PMID:
30520265
5.

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.

Bozickovic O, Skartveit L, Engelsen AST, Helland T, Jonsdottir K, Flågeng MH, Fenne IS, Janssen E, Lorens JB, Bjørkhaug L, Sagen JV, Mellgren G.

J Steroid Biochem Mol Biol. 2019 Jan;185:57-70. doi: 10.1016/j.jsbmb.2018.07.011. Epub 2018 Jul 23.

PMID:
30048685
6.

Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance.

Jokela TA, Engelsen AST, Rybicka A, Pelissier Vatter FA, Garbe JC, Miyano M, Tiron C, Ferariu D, Akslen LA, Stampfer MR, Lorens JB, LaBarge MA.

Front Cell Dev Biol. 2018 Apr 17;6:41. doi: 10.3389/fcell.2018.00041. eCollection 2018.

7.

High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia.

Pelissier Vatter FA, Schapiro D, Chang H, Borowsky AD, Lee JK, Parvin B, Stampfer MR, LaBarge MA, Bodenmiller B, Lorens JB.

Cell Rep. 2018 Apr 24;23(4):1205-1219. doi: 10.1016/j.celrep.2018.03.114.

8.

Lower Cancer Incidence-Warfarin Effect or Immortal Time Bias?-Reply.

Haaland GS, Falk RS, Lorens JB.

JAMA Intern Med. 2018 Apr 1;178(4):585-586. doi: 10.1001/jamainternmed.2018.0364. No abstract available.

PMID:
29610893
9.

Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.

Ludwig KF, Du W, Sorrelle NB, Wnuk-Lipinska K, Topalovski M, Toombs JE, Cruz VH, Yabuuchi S, Rajeshkumar NV, Maitra A, Lorens JB, Brekken RA.

Cancer Res. 2018 Jan 1;78(1):246-255. doi: 10.1158/0008-5472.CAN-17-1973. Epub 2017 Nov 27.

10.

Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years.

Haaland GS, Falk RS, Straume O, Lorens JB.

JAMA Intern Med. 2017 Dec 1;177(12):1774-1780. doi: 10.1001/jamainternmed.2017.5512.

11.

Clear Cell Renal Cell Carcinoma is linked to Epithelial-to-Mesenchymal Transition and to Fibrosis.

Landolt L, Eikrem Ø, Strauss P, Scherer A, Lovett DH, Beisland C, Finne K, Osman T, Ibrahim MM, Gausdal G, Ahmed L, Lorens JB, Thiery JP, Tan TZ, Sekulic M, Marti HP.

Physiol Rep. 2017 Jun;5(11). pii: e13305. doi: 10.14814/phy2.13305. Erratum in: Physiol Rep. 2018 Apr;6(8):e13671.

12.

Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity.

Terry S, Buart S, Tan TZ, Gros G, Noman MZ, Lorens JB, Mami-Chouaib F, Thiery JP, Chouaib S.

Oncoimmunology. 2017 Jan 17;6(2):e1271858. doi: 10.1080/2162402X.2016.1271858. eCollection 2017.

13.

Microsphere cytometry to interrogate microenvironment-dependent cell signaling.

Ertsås HC, Nolan GP, LaBarge MA, Lorens JB.

Integr Biol (Camb). 2017 Feb 20;9(2):123-134. doi: 10.1039/c6ib00207b.

PMID:
28102399
14.

Antiviral Screening of Multiple Compounds against Ebola Virus.

Dowall SD, Bewley K, Watson RJ, Vasan SS, Ghosh C, Konai MM, Gausdal G, Lorens JB, Long J, Barclay W, Garcia-Dorival I, Hiscox J, Bosworth A, Taylor I, Easterbrook L, Pitman J, Summers S, Chan-Pensley J, Funnell S, Vipond J, Charlton S, Haldar J, Hewson R, Carroll MW.

Viruses. 2016 Oct 27;8(11). pii: E277.

15.

Adaptive mechanisms of resistance to anti-neoplastic agents.

Ferreira BI, Lie MK, Engelsen AST, Machado S, Link W, Lorens JB.

Medchemcomm. 2016 Oct 21;8(1):53-66. doi: 10.1039/c6md00394j. eCollection 2017 Jan 1. Review.

16.

A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.

Ocal O, Pashkov V, Kollipara RK, Zolghadri Y, Cruz VH, Hale MA, Heath BR, Artyukhin AB, Christie AL, Tsoulfas P, Lorens JB, Swift GH, Brekken RA, Wilkie TM.

Dis Model Mech. 2015 Oct 1;8(10):1201-11. doi: 10.1242/dmm.020933.

17.

Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis.

Kirane A, Ludwig KF, Sorrelle N, Haaland G, Sandal T, Ranaweera R, Toombs JE, Wang M, Dineen SP, Micklem D, Dellinger MT, Lorens JB, Brekken RA.

Cancer Res. 2015 Sep 15;75(18):3699-705. doi: 10.1158/0008-5472.CAN-14-2887-T. Epub 2015 Jul 23.

18.

Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis.

Hellesøy M, Lorens JB.

Mol Biol Cell. 2015 Jul 15;26(14):2698-711. doi: 10.1091/mbc.E14-09-1378. Epub 2015 May 28.

19.

Vimentin-ERK Signaling Uncouples Slug Gene Regulatory Function.

Virtakoivu R, Mai A, Mattila E, De Franceschi N, Imanishi SY, Corthals G, Kaukonen R, Saari M, Cheng F, Torvaldson E, Kosma VM, Mannermaa A, Muharram G, Gilles C, Eriksson J, Soini Y, Lorens JB, Ivaska J.

Cancer Res. 2015 Jun 1;75(11):2349-62. doi: 10.1158/0008-5472.CAN-14-2842. Epub 2015 Apr 8.

20.

The immortality two-step.

Lorens JB.

Cell Cycle. 2015;14(6):798. doi: 10.1080/15384101.2015.1006560. No abstract available.

21.

Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties.

Nikolaisen J, Nilsson LI, Pettersen IK, Willems PH, Lorens JB, Koopman WJ, Tronstad KJ.

PLoS One. 2014 Jul 2;9(7):e101365. doi: 10.1371/journal.pone.0101365. eCollection 2014.

22.

Akt1 activity regulates vessel maturation in a tissue engineering model of angiogenesis.

Hellesøy M, Blois AL, Tiron CE, Mannelqvist M, Akslen LA, Lorens JB.

Tissue Eng Part A. 2014 Oct;20(19-20):2590-603. doi: 10.1089/ten.TEA.2013.0399. Epub 2014 Aug 21.

PMID:
24957363
23.

Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets.

Micklem DR, Blø M, Bergström P, Hodneland E, Tiron C, Høiby T, Gjerdrum C, Hammarsten O, Lorens JB.

BMC Biotechnol. 2014 Jun 21;14:57. doi: 10.1186/1472-6750-14-57.

24.

Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors.

Pelissier FA, Garbe JC, Ananthanarayanan B, Miyano M, Lin C, Jokela T, Kumar S, Stampfer MR, Lorens JB, LaBarge MA.

Cell Rep. 2014 Jun 26;7(6):1926-39. doi: 10.1016/j.celrep.2014.05.021. Epub 2014 Jun 5.

25.

Molecular deconstruction, detection, and computational prediction of microenvironment-modulated cellular responses to cancer therapeutics.

Labarge MA, Parvin B, Lorens JB.

Adv Drug Deliv Rev. 2014 Apr;69-70:123-31. doi: 10.1016/j.addr.2014.02.009. Epub 2014 Feb 26. Review.

26.

Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation.

Pedersen TO, Blois AL, Xue Y, Xing Z, Sun Y, Finne-Wistrand A, Lorens JB, Fristad I, Leknes KN, Mustafa K.

Stem Cell Res Ther. 2014 Feb 17;5(1):23. doi: 10.1186/scrt412.

28.

Contextual compound screening for improved therapeutic discovery.

Evensen L, Odlo K, Micklem DR, Littlewood-Evans A, Wood J, Kuzniewski C, Altmann KH, Hansen TV, Lorens JB.

Chembiochem. 2013 Dec 16;14(18):2512-8. doi: 10.1002/cbic.201300409. Epub 2013 Nov 12.

PMID:
24222525
29.

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma.

Ben-Batalla I, Schultze A, Wroblewski M, Erdmann R, Heuser M, Waizenegger JS, Riecken K, Binder M, Schewe D, Sawall S, Witzke V, Cubas-Cordova M, Janning M, Wellbrock J, Fehse B, Hagel C, Krauter J, Ganser A, Lorens JB, Fiedler W, Carmeliet P, Pantel K, Bokemeyer C, Loges S.

Blood. 2013 Oct 3;122(14):2443-52. doi: 10.1182/blood-2013-03-491431. Epub 2013 Aug 27.

30.
31.

Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs.

Pedersen TO, Blois AL, Xing Z, Xue Y, Sun Y, Finne-Wistrand A, Akslen LA, Lorens JB, Leknes KN, Fristad I, Mustafa K.

Stem Cell Res Ther. 2013 May 17;4(3):52. doi: 10.1186/scrt202.

32.

p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model.

Olsen JR, Oyan AM, Rostad K, Hellem MR, Liu J, Li L, Micklem DR, Haugen H, Lorens JB, Rotter V, Ke XS, Lin B, Kalland KH.

PLoS One. 2013 May 1;8(5):e62547. doi: 10.1371/journal.pone.0062547. Print 2013.

33.

Domains I and IV of annexin A2 affect the formation and integrity of in vitro capillary-like networks.

Raddum AM, Evensen L, Hollås H, Grindheim AK, Lorens JB, Vedeler A.

PLoS One. 2013;8(3):e60281. doi: 10.1371/journal.pone.0060281. Epub 2013 Mar 29. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/c39f6c86-6829-4bd5-9841-19b8882ea421.

34.

Nitroreductase, a near-infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer.

McCormack E, Silden E, West RM, Pavlin T, Micklem DR, Lorens JB, Haug BE, Cooper ME, Gjertsen BT.

Cancer Res. 2013 Feb 15;73(4):1276-86. doi: 10.1158/0008-5472.CAN-12-2649. Epub 2012 Dec 10.

35.

Camptothecin-7-yl-methanthiole: semisynthesis and biological evaluation.

Christodoulou MS, Zunino F, Zuco V, Borrelli S, Comi D, Fontana G, Martinelli M, Lorens JB, Evensen L, Sironi M, Pieraccini S, Dalla Via L, Gia OM, Passarella D.

ChemMedChem. 2012 Dec;7(12):2134-43. doi: 10.1002/cmdc.201200322. Epub 2012 Oct 19.

PMID:
23086693
36.

Soluble mediators released by acute myeloid leukemia cells increase capillary-like networks.

Hatfield KJ, Evensen L, Reikvam H, Lorens JB, Bruserud Ø.

Eur J Haematol. 2012 Dec;89(6):478-90. doi: 10.1111/ejh.12016. Epub 2012 Oct 26.

PMID:
23046151
37.

Image-based high-throughput screening for inhibitors of angiogenesis.

Evensen L, Link W, Lorens JB.

Methods Mol Biol. 2013;931:139-51. doi: 10.1007/978-1-62703-056-4_8.

PMID:
23027002
38.

A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.

Radi M, Evensen L, Dreassi E, Zamperini C, Caporicci M, Falchi F, Musumeci F, Schenone S, Lorens JB, Botta M.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5579-83. doi: 10.1016/j.bmcl.2012.07.014. Epub 2012 Jul 13.

PMID:
22853993
39.

Osteogenic stimulatory conditions enhance growth and maturation of endothelial cell microvascular networks in culture with mesenchymal stem cells.

Pedersen TO, Blois AL, Xue Y, Xing Z, Cottler-Fox M, Fristad I, Leknes KN, Lorens JB, Mustafa K.

J Tissue Eng. 2012;3(1):2041731412443236. doi: 10.1177/2041731412443236. Epub 2012 Apr 4.

40.

Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines.

Oveland E, Wergeland L, Hovland R, Lorens JB, Gjertsen BT, Fladmark KE.

Cell Biol Toxicol. 2012 Aug;28(4):201-12. doi: 10.1007/s10565-012-9216-z. Epub 2012 Mar 16.

PMID:
22422053
41.

Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.

McCormack E, Haaland I, Venås G, Forthun RB, Huseby S, Gausdal G, Knappskog S, Micklem DR, Lorens JB, Bruserud O, Gjertsen BT.

Leukemia. 2012 May;26(5):910-7. doi: 10.1038/leu.2011.315. Epub 2011 Nov 8.

PMID:
22064349
42.

S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest.

Sapkota D, Costea DE, Blø M, Bruland O, Lorens JB, Vasstrand EN, Ibrahim SO.

Oral Oncol. 2012 Mar;48(3):219-25. doi: 10.1016/j.oraloncology.2011.10.001. Epub 2011 Oct 26.

PMID:
22032898
43.

Isosteric replacement of the Z-enone with haloethyl ketone and E-enone in a resorcylic acid lactone series and biological evaluation.

Napolitano C, Natoni A, Santocanale C, Evensen L, Lorens JB, Murphy PV.

Bioorg Med Chem Lett. 2011 Feb 15;21(4):1167-70. doi: 10.1016/j.bmcl.2010.12.100. Epub 2010 Dec 24.

PMID:
21273066
44.

Imaged-based high-throughput screening for anti-angiogenic drug discovery.

Evensen L, Link W, Lorens JB.

Curr Pharm Des. 2010;16(35):3958-63. Review.

PMID:
21158729
45.

Synthesis and biological evaluation of new camptothecin derivatives obtained by modification of position 20.

Riva E, Comi D, Borrelli S, Colombo F, Danieli B, Borlak J, Evensen L, Lorens JB, Fontana G, Gia OM, Via LD, Passarella D.

Bioorg Med Chem. 2010 Dec 15;18(24):8660-8. doi: 10.1016/j.bmc.2010.09.069. Epub 2010 Oct 7.

PMID:
21071230
46.

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer.

Vuoriluoto K, Haugen H, Kiviluoto S, Mpindi JP, Nevo J, Gjerdrum C, Tiron C, Lorens JB, Ivaska J.

Oncogene. 2011 Mar 24;30(12):1436-48. doi: 10.1038/onc.2010.509. Epub 2010 Nov 8.

PMID:
21057535
47.

Efficient in vivo vascularization of tissue-engineering scaffolds.

Hegen A, Blois A, Tiron CE, Hellesøy M, Micklem DR, Nör JE, Akslen LA, Lorens JB.

J Tissue Eng Regen Med. 2011 Apr;5(4):e52-62. doi: 10.1002/term.336. Epub 2010 Sep 23.

48.

A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients.

Wang J, Daphu I, Pedersen PH, Miletic H, Hovland R, Mørk S, Bjerkvig R, Tiron C, McCormack E, Micklem D, Lorens JB, Immervoll H, Thorsen F.

Neuropathol Appl Neurobiol. 2011 Feb;37(2):189-205. doi: 10.1111/j.1365-2990.2010.01119.x.

PMID:
20819169
49.

High content screening: seeing is believing.

Zanella F, Lorens JB, Link W.

Trends Biotechnol. 2010 May;28(5):237-45. doi: 10.1016/j.tibtech.2010.02.005. Epub 2010 Mar 24. Review.

PMID:
20346526
50.

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.

Gjerdrum C, Tiron C, Høiby T, Stefansson I, Haugen H, Sandal T, Collett K, Li S, McCormack E, Gjertsen BT, Micklem DR, Akslen LA, Glackin C, Lorens JB.

Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1124-9. doi: 10.1073/pnas.0909333107. Epub 2009 Dec 28.

Supplemental Content

Loading ...
Support Center