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Autism spectrum disorder symptoms from ages 2 to 19 years: Implications for diagnosing adolescents and young adults.

Bal VH, Kim SH, Fok M, Lord C.

Autism Res. 2018 Aug 12. doi: 10.1002/aur.2004. [Epub ahead of print]


Autism spectrum disorder.

Lord C, Elsabbagh M, Baird G, Veenstra-Vanderweele J.

Lancet. 2018 Aug 2. pii: S0140-6736(18)31129-2. doi: 10.1016/S0140-6736(18)31129-2. [Epub ahead of print] Review.


Determinants of parent-delivered therapy interventions in children with cerebral palsy: A qualitative synthesis and checklist.

Lord C, Rapley T, Marcroft C, Pearse J, Basu A.

Child Care Health Dev. 2018 Jul 23. doi: 10.1111/cch.12592. [Epub ahead of print] Review.


Greater loss of horizontal force after a repeated-sprint test in footballers with a previous hamstring injury.

Lord C, Blazevich AJ, Drinkwater EJ, Ma'ayah F.

J Sci Med Sport. 2018 Jun 20. pii: S1440-2440(18)30259-7. doi: 10.1016/j.jsams.2018.06.008. [Epub ahead of print]


The shieldin complex mediates 53BP1-dependent DNA repair.

Noordermeer SM, Adam S, Setiaputra D, Barazas M, Pettitt SJ, Ling AK, Olivieri M, Álvarez-Quilón A, Moatti N, Zimmermann M, Annunziato S, Krastev DB, Song F, Brandsma I, Frankum J, Brough R, Sherker A, Landry S, Szilard RK, Munro MM, McEwan A, Goullet de Rugy T, Lin ZY, Hart T, Moffat J, Gingras AC, Martin A, van Attikum H, Jonkers J, Lord CJ, Rottenberg S, Durocher D.

Nature. 2018 Aug;560(7716):117-121. doi: 10.1038/s41586-018-0340-7. Epub 2018 Jul 18.


Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.

Holme H, Gulati A, Brough R, Fleuren EDG, Bajrami I, Campbell J, Chong IY, Costa-Cabral S, Elliott R, Fenton T, Frankum J, Jones SE, Menon M, Miller R, Pemberton HN, Postel-Vinay S, Rafiq R, Selfe JL, von Kriegsheim A, Munoz AG, Rodriguez J, Shipley J, van der Graaf WTA, Williamson CT, Ryan CJ, Pettitt S, Ashworth A, Strauss SJ, Lord CJ.

Sci Rep. 2018 Jul 13;8(1):10614. doi: 10.1038/s41598-018-29043-z.


CD177-mediated nanoparticle targeting of human and mouse neutrophils.

Miettinen HM, Gripentrog JM, Lord CI, Nagy JO.

PLoS One. 2018 Jul 10;13(7):e0200444. doi: 10.1371/journal.pone.0200444. eCollection 2018.


Wild pigs as sentinels for hard ticks: A case study from south-central Florida.

Merrill MM, Boughton RK, Lord CC, Sayler KA, Wight B, Anderson WM, Wisely SM.

Int J Parasitol Parasites Wildl. 2018 Apr 30;7(2):161-170. doi: 10.1016/j.ijppaw.2018.04.003. eCollection 2018 Aug.


Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

Vinci M, Burford A, Molinari V, Kessler K, Popov S, Clarke M, Taylor KR, Pemberton HN, Lord CJ, Gutteridge A, Forshew T, Carvalho D, Marshall LV, Qin EY, Ingram WJ, Moore AS, Ng HK, Trabelsi S, H'mida-Ben Brahim D, Entz-Werle N, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Sunol M, Mora J, de Torres C, Cruz O, Carcaboso AM, Monje M, Mackay A, Jones C.

Nat Med. 2018 Aug;24(8):1204-1215. doi: 10.1038/s41591-018-0086-7. Epub 2018 Jul 2.


Synthetic lethal therapies for cancer: what's next after PARP inhibitors?

Ashworth A, Lord CJ.

Nat Rev Clin Oncol. 2018 Jun 28. doi: 10.1038/s41571-018-0055-6. [Epub ahead of print] Review.


Whole exome sequencing in the rat.

Foley JF, Phadke DP, Hardy O, Hardy S, Miller V, Madan A, Howard K, Kruse K, Lord C, Ramaiahgari S, Solomon GG, Shah RR, Pandiri AR, Herbert RA, Sills RC, Alex Merrick B.

BMC Genomics. 2018 Jun 20;19(1):487. doi: 10.1186/s12864-018-4858-8.


Identification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer.

Brough R, Gulati A, Haider S, Kumar R, Campbell J, Knudsen E, Pettitt SJ, Ryan CJ, Lord CJ.

Oncogene. 2018 Jun 18. doi: 10.1038/s41388-018-0368-z. [Epub ahead of print]


Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease.

Jia L, Chang X, Qian S, Liu C, Lord CC, Ahmed N, Lee CE, Lee S, Gautron L, Mitchell MC, Horton JD, Scherer PE, Elmquist JK.

Mol Metab. 2018 May 23. pii: S2212-8778(18)30014-0. doi: 10.1016/j.molmet.2018.05.015. [Epub ahead of print]


Statistical Learning is Associated with Autism Symptoms and Verbal Abilities in Young Children with Autism.

Jones RM, Tarpey T, Hamo A, Carberry C, Brouwer G, Lord C.

J Autism Dev Disord. 2018 May 31. doi: 10.1007/s10803-018-3625-7. [Epub ahead of print]


Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets.

Krastev DB, Pettitt SJ, Campbell J, Song F, Tanos BE, Stoynov SS, Ashworth A, Lord CJ.

Nat Commun. 2018 May 22;9(1):2016. doi: 10.1038/s41467-018-04466-4.


The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

Barazas M, Annunziato S, Pettitt SJ, de Krijger I, Ghezraoui H, Roobol SJ, Lutz C, Frankum J, Song FF, Brough R, Evers B, Gogola E, Bhin J, van de Ven M, van Gent DC, Jacobs JJL, Chapman R, Lord CJ, Jonkers J, Rottenberg S.

Cell Rep. 2018 May 15;23(7):2107-2118. doi: 10.1016/j.celrep.2018.04.046.


Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.

Pettitt SJ, Krastev DB, Brandsma I, Dréan A, Song F, Aleksandrov R, Harrell MI, Menon M, Brough R, Campbell J, Frankum J, Ranes M, Pemberton HN, Rafiq R, Fenwick K, Swain A, Guettler S, Lee JM, Swisher EM, Stoynov S, Yusa K, Ashworth A, Lord CJ.

Nat Commun. 2018 May 10;9(1):1849. doi: 10.1038/s41467-018-03917-2.


Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.

Khalique S, Naidoo K, Attygalle AD, Kriplani D, Daley F, Lowe A, Campbell J, Jones T, Hubank M, Fenwick K, Matthews N, Rust AG, Lord CJ, Banerjee S, Natrajan R.

J Pathol Clin Res. 2018 Jul;4(3):154-166. doi: 10.1002/cjp2.103. Epub 2018 Jul 20.


E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer.

Bajrami I, Marlow R, van de Ven M, Brough R, Pemberton HN, Frankum J, Song F, Rafiq R, Konde A, Krastev DB, Menon M, Campbell J, Gulati A, Kumar R, Pettitt SJ, Gurden MD, Cardenosa ML, Chong I, Gazinska P, Wallberg F, Sawyer EJ, Martin LA, Dowsett M, Linardopoulos S, Natrajan R, Ryan CJ, Derksen PWB, Jonkers J, Tutt ANJ, Ashworth A, Lord CJ.

Cancer Discov. 2018 Apr;8(4):498-515. doi: 10.1158/2159-8290.CD-17-0603.


POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels.

Caron A, Dungan Lemko HM, Castorena CM, Fujikawa T, Lee S, Lord CC, Ahmed N, Lee CE, Holland WL, Liu C, Elmquist JK.

Elife. 2018 Mar 12;7. pii: e33710. doi: 10.7554/eLife.33710.


Post-operative arterio-venous fistula blood flow influences primary and secondary patency following access surgery.

Benaragama KS, Barwell J, Lord C, John BJ, Babber A, Sandoval S, Lindsey B, Fernando B.

J Ren Care. 2018 Mar 9. doi: 10.1111/jorc.12238. [Epub ahead of print]


Driver Oncogenes but Not as We Know Them: Targetable Fusion Genes in Breast Cancer.

Natrajan R, Tutt ANJ, Lord CJ.

Cancer Discov. 2018 Mar;8(3):272-275. doi: 10.1158/2159-8290.CD-18-0091.


DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.

Touat M, Sourisseau T, Dorvault N, Chabanon RM, Garrido M, Morel D, Krastev DB, Bigot L, Adam J, Frankum JR, Durand S, Pontoizeau C, Souquère S, Kuo MS, Sauvaigo S, Mardakheh F, Sarasin A, Olaussen KA, Friboulet L, Bouillaud F, Pierron G, Ashworth A, Lombès A, Lord CJ, Soria JC, Postel-Vinay S.

J Clin Invest. 2018 Apr 2;128(4):1671-1687. doi: 10.1172/JCI90277. Epub 2018 Mar 19.


Damaging de novo mutations diminish motor skills in children on the autism spectrum.

Buja A, Volfovsky N, Krieger AM, Lord C, Lash AE, Wigler M, Iossifov I.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1859-E1866. doi: 10.1073/pnas.1715427115. Epub 2018 Feb 6.


Promoting Interprofessional Collaborative Practice Through Simulation.

Alfes CM, Rutherford-Hemming T, Schroeder-Jenkinson CM, Lord CB, Zimmermann E.

Nurs Educ Perspect. 2018 Sep/Oct;39(5):322-323. doi: 10.1097/01.NEP.0000000000000285.


Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer.

Witkiewicz AK, Chung S, Brough R, Vail P, Franco J, Lord CJ, Knudsen ES.

Cell Rep. 2018 Jan 30;22(5):1185-1199. doi: 10.1016/j.celrep.2018.01.022.


Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels.

Campbell J, Ryan CJ, Lord CJ.

Methods Mol Biol. 2018;1711:83-99. doi: 10.1007/978-1-4939-7493-1_5.


An open resource for transdiagnostic research in pediatric mental health and learning disorders.

Alexander LM, Escalera J, Ai L, Andreotti C, Febre K, Mangone A, Vega-Potler N, Langer N, Alexander A, Kovacs M, Litke S, O'Hagan B, Andersen J, Bronstein B, Bui A, Bushey M, Butler H, Castagna V, Camacho N, Chan E, Citera D, Clucas J, Cohen S, Dufek S, Eaves M, Fradera B, Gardner J, Grant-Villegas N, Green G, Gregory C, Hart E, Harris S, Horton M, Kahn D, Kabotyanski K, Karmel B, Kelly SP, Kleinman K, Koo B, Kramer E, Lennon E, Lord C, Mantello G, Margolis A, Merikangas KR, Milham J, Minniti G, Neuhaus R, Levine A, Osman Y, Parra LC, Pugh KR, Racanello A, Restrepo A, Saltzman T, Septimus B, Tobe R, Waltz R, Williams A, Yeo A, Castellanos FX, Klein A, Paus T, Leventhal BL, Craddock RC, Koplewicz HS, Milham MP.

Sci Data. 2017 Dec 19;4:170181. doi: 10.1038/sdata.2017.181.


Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer.

Naidoo K, Wai PT, Maguire SL, Daley F, Haider S, Kriplani D, Campbell J, Mirza H, Grigoriadis A, Tutt A, Moseley PM, Abdel-Fatah TMA, Chan SYT, Madhusudan S, Rhaka EA, Ellis IO, Lord CJ, Yuan Y, Green AR, Natrajan R.

Mol Cancer Ther. 2018 Jan;17(1):306-315. doi: 10.1158/1535-7163.MCT-17-0760. Epub 2017 Nov 13.


Change in knee flexor torque after fatiguing exercise identifies previous hamstring injury in football players.

Lord C, Ma'ayah F, Blazevich AJ.

Scand J Med Sci Sports. 2018 Mar;28(3):1235-1243. doi: 10.1111/sms.13007. Epub 2018 Jan 8.


Distribution and host associations of ixodid ticks collected from wildlife in Florida, USA.

Hertz JC, Ferree Clemons BC, Lord CC, Allan SA, Kaufman PE.

Exp Appl Acarol. 2017 Oct;73(2):223-236. doi: 10.1007/s10493-017-0183-1. Epub 2017 Nov 6.


ATR Is a Therapeutic Target in Synovial Sarcoma.

Jones SE, Fleuren EDG, Frankum J, Konde A, Williamson CT, Krastev DB, Pemberton HN, Campbell J, Gulati A, Elliott R, Menon M, Selfe JL, Brough R, Pettitt SJ, Niedzwiedz W, van der Graaf WTA, Shipley J, Ashworth A, Lord CJ.

Cancer Res. 2017 Dec 15;77(24):7014-7026. doi: 10.1158/0008-5472.CAN-17-2056. Epub 2017 Oct 16.


A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events.

Ryan CJ, Kennedy S, Bajrami I, Matallanas D, Lord CJ.

Cell Syst. 2017 Oct 25;5(4):399-409.e5. doi: 10.1016/j.cels.2017.09.011. Epub 2017 Oct 11.


Directing the use of DDR kinase inhibitors in cancer treatment.

Brandsma I, Fleuren EDG, Williamson CT, Lord CJ.

Expert Opin Investig Drugs. 2017 Dec;26(12):1341-1355. doi: 10.1080/13543784.2017.1389895. Epub 2017 Oct 14. Review.


Serotonergic Control of Metabolic Homeostasis.

Wyler SC, Lord CC, Lee S, Elmquist JK, Liu C.

Front Cell Neurosci. 2017 Sep 20;11:277. doi: 10.3389/fncel.2017.00277. eCollection 2017. Review.


Simple, Transparent, and Flexible Automated Quality Assessment Procedures for Ambulatory Electrodermal Activity Data.

Kleckner IR, Jones RM, Wilder-Smith O, Wormwood JB, Akcakaya M, Quigley KS, Lord C, Goodwin MS, Kleckner IR, Jones RM, Wilder-Smith O, Wormwood JB, Akcakaya M, Quigley KS, Lord C, Goodwin MS, Lord C, Jones RM, Wormwood JB, Quigley KS, Goodwin MS, Akcakaya M, Wilder-Smith O, Kleckner IR.

IEEE Trans Biomed Eng. 2018 Jul;65(7):1460-1467. doi: 10.1109/TBME.2017.2758643. Epub 2017 Oct 2.


Longitudinal follow-up of academic achievement in children with autism from age 2 to 18.

Kim SH, Bal VH, Lord C.

J Child Psychol Psychiatry. 2018 Mar;59(3):258-267. doi: 10.1111/jcpp.12808. Epub 2017 Sep 26.


Environmental Drivers of Seasonal Patterns of Host Utilization by Culiseta melanura (Diptera: Culicidae) in Florida.

Blosser EM, Lord CC, Stenn T, Acevedo C, Hassan HK, Reeves LE, Unnasch TR, Burkett-Cadena ND.

J Med Entomol. 2017 Sep 1;54(5):1365-1374. doi: 10.1093/jme/tjx140.


Children with autism spectrum disorder who improve with fever: Insights from the Simons Simplex Collection.

Grzadzinski R, Lord C, Sanders SJ, Werling D, Bal VH.

Autism Res. 2018 Jan;11(1):175-184. doi: 10.1002/aur.1856. Epub 2017 Aug 31.


Hypercalcaemia secondary to ectopic parathyroid hormone expression in an adolescent with metastatic alveolar rhabdomyosarcoma.

Brooks R, Lord C, Davies JH, Gray JC.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26778. Epub 2017 Aug 26.


Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer.

Chong IY, Aronson L, Bryant H, Gulati A, Campbell J, Elliott R, Pettitt S, Wilkerson P, Lambros MB, Reis-Filho JS, Ramessur A, Davidson M, Chau I, Cunningham D, Ashworth A, Lord CJ.

Gut. 2017 Aug 22. pii: gutjnl-2017-314408. doi: 10.1136/gutjnl-2017-314408. [Epub ahead of print]


The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C.

Lord CC, Wyler SC, Wan R, Castorena CM, Ahmed N, Mathew D, Lee S, Liu C, Elmquist JK.

J Clin Invest. 2017 Sep 1;127(9):3402-3406. doi: 10.1172/JCI93362. Epub 2017 Aug 14.


Sex differences in age-related changes in the sleep-wake cycle.

Carrier J, Semba K, Deurveilher S, Drogos L, Cyr-Cronier J, Lord C, Sekerovick Z.

Front Neuroendocrinol. 2017 Oct;47:66-85. doi: 10.1016/j.yfrne.2017.07.004. Epub 2017 Jul 27. Review.


Transmission risk of two chikungunya lineages by invasive mosquito vectors from Florida and the Dominican Republic.

Alto BW, Wiggins K, Eastmond B, Velez D, Lounibos LP, Lord CC.

PLoS Negl Trop Dis. 2017 Jul 27;11(7):e0005724. doi: 10.1371/journal.pntd.0005724. eCollection 2017 Jul.


CancerGD: A Resource for Identifying and Interpreting Genetic Dependencies in Cancer.

Bridgett S, Campbell J, Lord CJ, Ryan CJ.

Cell Syst. 2017 Jul 26;5(1):82-86.e3. doi: 10.1016/j.cels.2017.06.002. Epub 2017 Jul 12.


Structural basis for recruitment of BRCA2 by PALB2.

Oliver AW, Swift S, Lord CJ, Ashworth A, Pearl LH.

EMBO Rep. 2017 Jul;18(7):1264. doi: 10.15252/embr.201744508. No abstract available.


Dr. Havdahl et al. reply.

Havdahl KA, Bal VH, Huerta M, Pickles A, Øyen AS, Stoltenberg C, Lord C, Bishop SL.

J Am Acad Child Adolesc Psychiatry. 2017 Jul;56(7):619-620. doi: 10.1016/j.jaac.2017.05.010. Epub 2017 Jun 21. No abstract available.


Functionally Null RAD51D Missense Mutation Associates Strongly with Ovarian Carcinoma.

Rivera B, Di Iorio M, Frankum J, Nadaf J, Fahiminiya S, Arcand SL, Burk DL, Grapton D, Tomiak E, Hastings V, Hamel N, Wagener R, Aleynikova O, Giroux S, Hamdan FF, Dionne-Laporte A, Zogopoulos G, Rousseau F, Berghuis AM, Provencher D, Rouleau GA, Michaud JL, Mes-Masson AM, Majewski J, Bens S, Siebert R, Narod SA, Akbari MR, Lord CJ, Tonin PN, Orthwein A, Foulkes WD.

Cancer Res. 2017 Aug 15;77(16):4517-4529. doi: 10.1158/0008-5472.CAN-17-0190. Epub 2017 Jun 23.


The influence of parental concern on the utility of autism diagnostic instruments.

Havdahl KA, Bishop SL, Surén P, Øyen AS, Lord C, Pickles A, von Tetzchner S, Schjølberg S, Gunnes N, Hornig M, Lipkin WI, Susser E, Bresnahan M, Magnus P, Stenberg N, Reichborn-Kjennerud T, Stoltenberg C.

Autism Res. 2017 Oct;10(10):1672-1686. doi: 10.1002/aur.1817. Epub 2017 Jun 22.


Evaluating the quality of peer interactions in children and adolescents with autism with the Penn Interactive Peer Play Scale (PIPPS).

Jones RM, Pickles A, Lord C.

Mol Autism. 2017 Jun 17;8:28. doi: 10.1186/s13229-017-0144-x. eCollection 2017.

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