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Items: 9


Disease Heritability Inferred from Familial Relationships Reported in Medical Records.

Polubriaginof FCG, Vanguri R, Quinnies K, Belbin GM, Yahi A, Salmasian H, Lorberbaum T, Nwankwo V, Li L, Shervey MM, Glowe P, Ionita-Laza I, Simmerling M, Hripcsak G, Bakken S, Goldstein D, Kiryluk K, Kenny EE, Dudley J, Vawdrey DK, Tatonetti NP.

Cell. 2018 Jun 14;173(7):1692-1704.e11. doi: 10.1016/j.cell.2018.04.032. Epub 2018 May 17.


Reply: Combination Therapy With Ceftriaxone and Lansoprazole, Acquired Long QT Syndrome and Torsades de Pointes Risk.

Lorberbaum T, Tatonetti NP.

J Am Coll Cardiol. 2017 Apr 11;69(14):1877-1878. doi: 10.1016/j.jacc.2016.12.042. No abstract available.


Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation.

Lorberbaum T, Sampson KJ, Chang JB, Iyer V, Woosley RL, Kass RS, Tatonetti NP.

J Am Coll Cardiol. 2016 Oct 18;68(16):1756-1764. doi: 10.1016/j.jacc.2016.07.761.


A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.

Gayvert KM, Dardenne E, Cheung C, Boland MR, Lorberbaum T, Wanjala J, Chen Y, Rubin MA, Tatonetti NP, Rickman DS, Elemento O.

Cell Rep. 2016 Jun 14;15(11):2348-56. doi: 10.1016/j.celrep.2016.05.037. Epub 2016 Jun 2.


An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval.

Lorberbaum T, Sampson KJ, Woosley RL, Kass RS, Tatonetti NP.

Drug Saf. 2016 May;39(5):433-41. doi: 10.1007/s40264-016-0393-1.


Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms.

Boland MR, Jacunski A, Lorberbaum T, Romano JD, Moskovitch R, Tatonetti NP.

Wiley Interdiscip Rev Syst Biol Med. 2016 Mar-Apr;8(2):104-22. doi: 10.1002/wsbm.1323. Epub 2015 Nov 12. Review.


Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling.

Vilar S, Lorberbaum T, Hripcsak G, Tatonetti NP.

PLoS One. 2015 Jun 12;10(6):e0129974. doi: 10.1371/journal.pone.0129974. eCollection 2015.


Systems pharmacology augments drug safety surveillance.

Lorberbaum T, Nasir M, Keiser MJ, Vilar S, Hripcsak G, Tatonetti NP.

Clin Pharmacol Ther. 2015 Feb;97(2):151-8. doi: 10.1002/cpt.2. Epub 2014 Dec 20.


Similarity-based modeling in large-scale prediction of drug-drug interactions.

Vilar S, Uriarte E, Santana L, Lorberbaum T, Hripcsak G, Friedman C, Tatonetti NP.

Nat Protoc. 2014 Sep;9(9):2147-63. doi: 10.1038/nprot.2014.151. Epub 2014 Aug 14.

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