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Items: 1 to 50 of 88

1.

Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release.

Thompson EA, Darrah PA, Foulds KE, Hoffer E, Caffrey-Carr A, Norenstedt S, Perbeck L, Seder RA, Kedl RM, Loré K.

Cell Rep. 2019 Jul 30;28(5):1127-1135.e4. doi: 10.1016/j.celrep.2019.06.087.

2.

Recurrent Herpes Zoster Ophthalmicus in a Patient With a Novel Toll-Like Receptor 3 Variant Linked to Compromised Activation Capacity in Fibroblasts.

Liang F, Glans H, Enoksson SL, Kolios AGA, Loré K, Nilsson J.

J Infect Dis. 2019 Jul 2. pii: jiz229. doi: 10.1093/infdis/jiz229. [Epub ahead of print]

PMID:
31268141
3.

Comparative analysis of the germinal center response by flow cytometry and immunohistology.

Lindgren G, Ols S, Thompson EA, Loré K.

J Immunol Methods. 2019 Sep;472:16-24. doi: 10.1016/j.jim.2019.06.010. Epub 2019 Jun 10.

PMID:
31194971
4.

Imaging the early fate of mRNA vaccines.

Ols S, Loré K.

Nat Biomed Eng. 2019 May;3(5):331-332. doi: 10.1038/s41551-019-0399-y. No abstract available.

PMID:
31073175
5.

Corrigendum: Induction of Robust B Cell Responses After Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells.

Lindgren G, Ols S, Liang F, Thompson EA, Lin A, Hellgren F, Bahl K, John S, Yuzhakov O, Hassett KJ, Brito LA, Salter H, Ciaramella G, Loré K.

Front Immunol. 2019 Apr 2;10:614. doi: 10.3389/fimmu.2019.00614. eCollection 2019.

6.

Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus.

Marcandalli J, Fiala B, Ols S, Perotti M, de van der Schueren W, Snijder J, Hodge E, Benhaim M, Ravichandran R, Carter L, Sheffler W, Brunner L, Lawrenz M, Dubois P, Lanzavecchia A, Sallusto F, Lee KK, Veesler D, Correnti CE, Stewart LJ, Baker D, Loré K, Perez L, King NP.

Cell. 2019 Mar 7;176(6):1420-1431.e17. doi: 10.1016/j.cell.2019.01.046.

7.

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates.

Cassetta L, Baekkevold ES, Brandau S, Bujko A, Cassatella MA, Dorhoi A, Krieg C, Lin A, Loré K, Marini O, Pollard JW, Roussel M, Scapini P, Umansky V, Adema GJ.

Cancer Immunol Immunother. 2019 Apr;68(4):687-697. doi: 10.1007/s00262-019-02302-2. Epub 2019 Jan 25. Review.

8.

TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.

Thompson EA, Ols S, Miura K, Rausch K, Narum DL, Spångberg M, Juraska M, Wille-Reece U, Weiner A, Howard RF, Long CA, Duffy PE, Johnston L, O'Neil CP, Loré K.

JCI Insight. 2018 May 17;3(10). pii: 120692. doi: 10.1172/jci.insight.120692. eCollection 2018 May 17.

9.

Granulocytes: New Members of the Antigen-Presenting Cell Family.

Lin A, Loré K.

Front Immunol. 2017 Dec 11;8:1781. doi: 10.3389/fimmu.2017.01781. eCollection 2017. Review.

10.

A deep learning framework for causal shape transformation.

Lore KG, Stoecklein D, Davies M, Ganapathysubramanian B, Sarkar S.

Neural Netw. 2018 Feb;98:305-317. doi: 10.1016/j.neunet.2017.12.003. Epub 2017 Dec 18.

PMID:
29301111
11.

Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells.

Lindgren G, Ols S, Liang F, Thompson EA, Lin A, Hellgren F, Bahl K, John S, Yuzhakov O, Hassett KJ, Brito LA, Salter H, Ciaramella G, Loré K.

Front Immunol. 2017 Nov 13;8:1539. doi: 10.3389/fimmu.2017.01539. eCollection 2017. Erratum in: Front Immunol. 2019 Apr 02;10:614.

12.

Rhesus Macaque Myeloid-Derived Suppressor Cells Demonstrate T Cell Inhibitory Functions and Are Transiently Increased after Vaccination.

Lin A, Liang F, Thompson EA, Vono M, Ols S, Lindgren G, Hassett K, Salter H, Ciaramella G, Loré K.

J Immunol. 2018 Jan 1;200(1):286-294. doi: 10.4049/jimmunol.1701005. Epub 2017 Nov 27.

13.

Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques.

Liang F, Lindgren G, Lin A, Thompson EA, Ols S, Röhss J, John S, Hassett K, Yuzhakov O, Bahl K, Brito LA, Salter H, Ciaramella G, Loré K.

Mol Ther. 2017 Dec 6;25(12):2635-2647. doi: 10.1016/j.ymthe.2017.08.006. Epub 2017 Aug 12.

14.

Non-human primates as a model for understanding the mechanism of action of toll-like receptor-based vaccine adjuvants.

Thompson EA, Loré K.

Curr Opin Immunol. 2017 Aug;47:1-7. doi: 10.1016/j.coi.2017.06.006. Epub 2017 Jul 15. Review.

PMID:
28715767
15.

Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake.

Liang F, Lindgren G, Sandgren KJ, Thompson EA, Francica JR, Seubert A, De Gregorio E, Barnett S, O'Hagan DT, Sullivan NJ, Koup RA, Seder RA, Loré K.

Sci Transl Med. 2017 Jun 7;9(393). pii: eaal2094. doi: 10.1126/scitranslmed.aal2094.

PMID:
28592561
16.

Prospects for induction of CD8 T cell-mediated immunity to Zika virus infection by yellow fever virus vaccination.

Blom K, Sandberg JT, Loré K, Ljunggren HG.

J Intern Med. 2017 Sep;282(3):206-208. doi: 10.1111/joim.12638. Epub 2017 Jul 13. No abstract available.

17.

Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach.

Martinez-Murillo P, Tran K, Guenaga J, Lindgren G, Àdori M, Feng Y, Phad GE, Vázquez Bernat N, Bale S, Ingale J, Dubrovskaya V, O'Dell S, Pramanik L, Spångberg M, Corcoran M, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB.

Immunity. 2017 May 16;46(5):804-817.e7. doi: 10.1016/j.immuni.2017.04.021.

18.

Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data.

Stoecklein D, Lore KG, Davies M, Sarkar S, Ganapathysubramanian B.

Sci Rep. 2017 Apr 12;7:46368. doi: 10.1038/srep46368.

19.

Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo.

Vono M, Lin A, Norrby-Teglund A, Koup RA, Liang F, Loré K.

Blood. 2017 Apr 6;129(14):1991-2001. doi: 10.1182/blood-2016-10-744441. Epub 2017 Jan 31.

20.

Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.

Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, Ackerman ME, Vargas-Inchaustegui DA, Whitney S, Doster MN, Binello N, Pegu P, Montefiori DC, Foulds K, Quinn DS, Donaldson M, Liang F, Loré K, Roederer M, Koup RA, McDermott A, Ma ZM, Miller CJ, Phan TB, Forthal DN, Blackburn M, Caccuri F, Bissa M, Ferrari G, Kalyanaraman V, Ferrari MG, Thompson D, Robert-Guroff M, Ratto-Kim S, Kim JH, Michael NL, Phogat S, Barnett SW, Tartaglia J, Venzon D, Stablein DM, Alter G, Sekaly RP, Franchini G.

Nat Med. 2016 Oct 6;22(10):1192. doi: 10.1038/nm1016-1192a. No abstract available.

PMID:
27711066
21.

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.

Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, Ackerman ME, Vargas-Inchaustegui DA, Whitney S, Doster MN, Binello N, Pegu P, Montefiori DC, Foulds K, Quinn DS, Donaldson M, Liang F, Loré K, Roederer M, Koup RA, McDermott A, Ma ZM, Miller CJ, Phan TB, Forthal DN, Blackburn M, Caccuri F, Bissa M, Ferrari G, Kalyanaraman V, Ferrari MG, Thompson D, Robert-Guroff M, Ratto-Kim S, Kim JH, Michael NL, Phogat S, Barnett SW, Tartaglia J, Venzon D, Stablein DM, Alter G, Sekaly RP, Franchini G.

Nat Med. 2016 Jul;22(7):762-70. doi: 10.1038/nm.4105. Epub 2016 May 30. Erratum in: Nat Med. 2016 Oct 6;22(10 ):1192.

22.

Local innate immune responses in the vaccine adjuvant-injected muscle.

Liang F, Loré K.

Clin Transl Immunology. 2016 Apr 29;5(4):e74. doi: 10.1038/cti.2016.19. eCollection 2016 Apr. Review.

23.

Design and evaluation of surface and adjuvant modified PLGA microspheres for uptake by dendritic cells to improve vaccine responses.

Salvador A, Sandgren KJ, Liang F, Thompson EA, Koup RA, Pedraz JL, Hernandez RM, Loré K, Igartua M.

Int J Pharm. 2015 Dec 30;496(2):371-81. doi: 10.1016/j.ijpharm.2015.10.037. Epub 2015 Oct 22.

PMID:
26475970
24.

Correction: Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates.

Thompson EA, Liang F, Lindgren G, Sandgren KJ, Quinn KM, Darrah PA, Koup RA, Seder RA, Kedl RM, Loré K.

J Immunol. 2015 Oct 1;195(7):3497-8. doi: 10.4049/jimmunol.1501682. No abstract available.

25.

Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates.

Thompson EA, Liang F, Lindgren G, Sandgren KJ, Quinn KM, Darrah PA, Koup RA, Seder RA, Kedl RM, Loré K.

J Immunol. 2015 Aug 1;195(3):1015-24. doi: 10.4049/jimmunol.1500078. Epub 2015 Jun 29. Erratum in: J Immunol. 2015 Oct 1;195(7):3497-8.

26.

Dissociation of skeletal muscle for flow cytometric characterization of immune cells in macaques.

Liang F, Ploquin A, Hernández JD, Fausther-Bovendo H, Lindgren G, Stanley D, Martinez AS, Brenchley JM, Koup RA, Loré K, Sullivan NJ.

J Immunol Methods. 2015 Oct;425:69-78. doi: 10.1016/j.jim.2015.06.011. Epub 2015 Jun 20.

27.

Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells.

Calantone N, Wu F, Klase Z, Deleage C, Perkins M, Matsuda K, Thompson EA, Ortiz AM, Vinton CL, Ourmanov I, Loré K, Douek DC, Estes JD, Hirsch VM, Brenchley JM.

Immunity. 2014 Sep 18;41(3):493-502. doi: 10.1016/j.immuni.2014.08.014.

28.

Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells.

Wu C, Li B, Lu R, Koelle SJ, Yang Y, Jares A, Krouse AE, Metzger M, Liang F, Loré K, Wu CO, Donahue RE, Chen ISY, Weissman I, Dunbar CE.

Cell Stem Cell. 2014 Apr 3;14(4):486-499. doi: 10.1016/j.stem.2014.01.020.

29.

Type I interferon-dependent activation of NK cells by rAd28 or rAd35, but not rAd5, leads to loss of vector-insert expression.

Johnson MJ, Björkström NK, Petrovas C, Liang F, Gall JG, Loré K, Koup RA.

Vaccine. 2014 Feb 3;32(6):717-24. doi: 10.1016/j.vaccine.2013.11.055. Epub 2013 Dec 8.

30.

Coadministration of polyinosinic:polycytidylic acid and immunostimulatory complexes modifies antigen processing in dendritic cell subsets and enhances HIV gag-specific T cell immunity.

Quinn KM, Yamamoto A, Costa A, Darrah PA, Lindsay RW, Hegde ST, Johnson TR, Flynn BJ, Loré K, Seder RA.

J Immunol. 2013 Nov 15;191(10):5085-96. doi: 10.4049/jimmunol.1301730. Epub 2013 Oct 2.

31.

Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants.

Feng Y, Forsell MN, Flynn B, Adams W, Loré K, Seder R, Wyatt RT, Karlsson Hedestam GB.

Virology. 2013 Nov;446(1-2):56-65. doi: 10.1016/j.virol.2013.07.028. Epub 2013 Aug 15.

32.

Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation.

Sandgren KJ, Smed-Sörensen A, Forsell MN, Soldemo M, Adams WC, Liang F, Perbeck L, Koup RA, Wyatt RT, Karlsson Hedestam GB, Loré K.

J Immunol. 2013 Jul 1;191(1):60-9. doi: 10.4049/jimmunol.1202489. Epub 2013 May 31.

33.

Dendritic cell recruitment in response to skin antigen tests in HIV-1-infected individuals correlates with the level of T-cell infiltration.

Liang F, Bond E, Sandgren KJ, Smed-Sörensen A, Rangaka MX, Lange C, Koup RA, McComsey GA, Lederman MM, Wilkinson RJ, Andersson J, Loré K.

AIDS. 2013 Apr 24;27(7):1071-80. doi: 10.1097/QAD.0b013e32835ecaca.

34.

AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment.

Lindmark E, Chen Y, Georgoudaki AM, Dudziak D, Lindh E, Adams WC, Loré K, Winqvist O, Chambers BJ, Karlsson MC.

J Autoimmun. 2013 May;42:62-70. doi: 10.1016/j.jaut.2012.11.004. Epub 2012 Dec 21.

PMID:
23265639
35.

Targeting dendritic cells for improved HIV-1 vaccines.

Smed-Sörensen A, Loré K.

Adv Exp Med Biol. 2013;762:263-88. doi: 10.1007/978-1-4614-4433-6_10. Review.

PMID:
22975879
36.

Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity.

Johnson MJ, Petrovas C, Yamamoto T, Lindsay RW, Loré K, Gall JG, Gostick E, Lefebvre F, Cameron MJ, Price DA, Haddad E, Sekaly RP, Seder RA, Koup RA.

J Immunol. 2012 Jun 15;188(12):6109-18. doi: 10.4049/jimmunol.1103717. Epub 2012 May 14.

37.

Attenuation of CD4+ T-cell function by human adenovirus type 35 is mediated by the knob protein.

Adams WC, Berenson RJ, Karlsson Hedestam GB, Lieber A, Koup RA, Loré K.

J Gen Virol. 2012 Jun;93(Pt 6):1339-44. doi: 10.1099/vir.0.039222-0. Epub 2012 Feb 22.

PMID:
22357750
38.

In vitro stimulation and detection of IFNα production in human plasmacytoid dendritic cells.

Adams WC, Loré K.

Methods Mol Biol. 2012;820:215-30. doi: 10.1007/978-1-61779-439-1_13.

PMID:
22131034
39.

Human and rhesus plasmacytoid dendritic cell and B-cell responses to Toll-like receptor stimulation.

Gujer C, Sundling C, Seder RA, Karlsson Hedestam GB, Loré K.

Immunology. 2011 Nov;134(3):257-69. doi: 10.1111/j.1365-2567.2011.03484.x.

40.

Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations.

Bond E, Liang F, Sandgren KJ, Smed-Sörensen A, Bergman P, Brighenti S, Adams WC, Betemariam SA, Rangaka MX, Lange C, Wilkinson RJ, Andersson J, Loré K.

J Invest Dermatol. 2012 Jan;132(1):114-23. doi: 10.1038/jid.2011.246. Epub 2011 Aug 18.

41.

Dendritic cells at the interface of innate and adaptive immunity to HIV-1.

Smed-Sörensen A, Loré K.

Curr Opin HIV AIDS. 2011 Sep;6(5):405-10. doi: 10.1097/COH.0b013e328349b06b. Review.

PMID:
21743321
42.

Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation.

Adams WC, Gujer C, McInerney G, Gall JG, Petrovas C, Karlsson Hedestam GB, Koup RA, Loré K.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7499-504. doi: 10.1073/pnas.1017146108. Epub 2011 Apr 18.

43.

IFN-α produced by human plasmacytoid dendritic cells enhances T cell-dependent naïve B cell differentiation.

Gujer C, Sandgren KJ, Douagi I, Adams WC, Sundling C, Smed-Sörensen A, Seder RA, Karlsson Hedestam GB, Loré K.

J Leukoc Biol. 2011 Jun;89(6):811-21. doi: 10.1189/jlb.0810460. Epub 2011 Jan 13.

44.

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.

Sundling C, Forsell MN, O'Dell S, Feng Y, Chakrabarti B, Rao SS, Loré K, Mascola JR, Wyatt RT, Douagi I, Karlsson Hedestam GB.

J Exp Med. 2010 Aug 30;207(9):2003-17. doi: 10.1084/jem.20100025. Epub 2010 Aug 2. Erratum in: J Exp Med. 2010 Sep 27;207(10):2283.

45.

Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus.

Sundling C, O'Dell S, Douagi I, Forsell MN, Mörner A, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB.

J Virol. 2010 Sep;84(18):9086-95. doi: 10.1128/JVI.01015-10. Epub 2010 Jul 7.

46.

Novel adjuvants for B cell immune responses.

Loré K, Karlsson Hedestam GB.

Curr Opin HIV AIDS. 2009 Sep;4(5):441-6. doi: 10.1097/COH.0b013e32832da082. Review.

PMID:
20048709
47.

Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates.

Douagi I, Forsell MN, Sundling C, O'Dell S, Feng Y, Dosenovic P, Li Y, Seder R, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB.

J Virol. 2010 Feb;84(4):1683-95. doi: 10.1128/JVI.01896-09. Epub 2009 Dec 2.

48.

Neutrophil-derived hyperresistinemia in severe acute streptococcal infections.

Johansson L, Linnér A, Sundén-Cullberg J, Haggar A, Herwald H, Loré K, Treutiger CJ, Norrby-Teglund A.

J Immunol. 2009 Sep 15;183(6):4047-54. doi: 10.4049/jimmunol.0901541. Epub 2009 Aug 28.

49.

Techniques for time-efficient isolation of human skin dendritic cell subsets and assessment of their antigen uptake capacity.

Bond E, Adams WC, Smed-Sörensen A, Sandgren KJ, Perbeck L, Hofmann A, Andersson J, Loré K.

J Immunol Methods. 2009 Aug 31;348(1-2):42-56. doi: 10.1016/j.jim.2009.06.012. Epub 2009 Jul 2.

PMID:
19576898
50.

Abundant and superficial expression of C-type lectin receptors in ectocervix of women at risk of HIV infection.

Hirbod T, Kaldensjö T, Lopalco L, Klareskog E, Andersson S, Uberti-Foppa C, Ferrari D, Manghi M, Andersson J, Loré K, Broliden K.

J Acquir Immune Defic Syndr. 2009 Jul 1;51(3):239-47. doi: 10.1097/QAI.0b013e3181a74f89.

PMID:
19363450

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