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Items: 15


Cancer-Associated Long Noncoding RNA SMRT-2 Controls Epidermal Differentiation.

Lee CS, Mah A, Aros CJ, Lopez-Pajares V, Bhaduri A, Webster DE, Kretz M, Khavari PA.

J Invest Dermatol. 2018 Jun;138(6):1445-1449. doi: 10.1016/j.jid.2018.01.003. Epub 2018 Jan 31. No abstract available.


Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.

Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, Snyder M, Chang HY, Fraser P, Khavari PA.

Nat Genet. 2017 Oct;49(10):1522-1528. doi: 10.1038/ng.3935. Epub 2017 Aug 14.


Epidermal differentiation gene regulatory networks controlled by MAF and MAFB.

Labott AT, Lopez-Pajares V.

Cell Cycle. 2016 Jun 2;15(11):1405-9. doi: 10.1080/15384101.2016.1172148. Epub 2016 Apr 20.


Long non-coding RNA regulation of gene expression during differentiation.

Lopez-Pajares V.

Pflugers Arch. 2016 Jun;468(6):971-81. doi: 10.1007/s00424-016-1809-6. Epub 2016 Mar 21. Review.


Network Analysis Identifies Mitochondrial Regulation of Epidermal Differentiation by MPZL3 and FDXR.

Bhaduri A, Ungewickell A, Boxer LD, Lopez-Pajares V, Zarnegar BJ, Khavari PA.

Dev Cell. 2015 Nov 23;35(4):444-57. doi: 10.1016/j.devcel.2015.10.023.


CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation.

Sun BK, Boxer LD, Ransohoff JD, Siprashvili Z, Qu K, Lopez-Pajares V, Hollmig ST, Khavari PA.

Genes Dev. 2015 Nov 1;29(21):2225-30. doi: 10.1101/gad.267708.115.


A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation.

Lopez-Pajares V, Qu K, Zhang J, Webster DE, Barajas BC, Siprashvili Z, Zarnegar BJ, Boxer LD, Rios EJ, Tao S, Kretz M, Khavari PA.

Dev Cell. 2015 Mar 23;32(6):693-706. doi: 10.1016/j.devcel.2015.01.028.


ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4.

Bao X, Tang J, Lopez-Pajares V, Tao S, Qu K, Crabtree GR, Khavari PA.

Cell Stem Cell. 2013 Feb 7;12(2):193-203. doi: 10.1016/j.stem.2012.12.014.


Genetic pathways in disorders of epidermal differentiation.

Lopez-Pajares V, Yan K, Zarnegar BJ, Jameson KL, Khavari PA.

Trends Genet. 2013 Jan;29(1):31-40. doi: 10.1016/j.tig.2012.10.005. Epub 2012 Nov 8. Review.


MDM2 and MDMX: Alone and together in regulation of p53.

Shadfan M, Lopez-Pajares V, Yuan ZM.

Transl Cancer Res. 2012 Aug;1(2):88-89.


Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63.

Zarnegar BJ, Webster DE, Lopez-Pajares V, Vander Stoep Hunt B, Qu K, Yan KJ, Berk DR, Sen GL, Khavari PA.

Am J Hum Genet. 2012 Sep 7;91(3):435-43. doi: 10.1016/j.ajhg.2012.07.007. Epub 2012 Aug 23.


Suppression of progenitor differentiation requires the long noncoding RNA ANCR.

Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA.

Genes Dev. 2012 Feb 15;26(4):338-43. doi: 10.1101/gad.182121.111. Epub 2012 Feb 2.


Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation.

Huang Y, Zhang J, McHenry KT, Kim MM, Zeng W, Lopez-Pajares V, Dibble CC, Mizgerd JP, Yuan ZM.

Cancer Res. 2008 Nov 15;68(22):9131-6. doi: 10.1158/0008-5472.CAN-08-3025.


Phosphorylation of MDMX mediated by Akt leads to stabilization and induces 14-3-3 binding.

Lopez-Pajares V, Kim MM, Yuan ZM.

J Biol Chem. 2008 May 16;283(20):13707-13. doi: 10.1074/jbc.M710030200. Epub 2008 Mar 20.


RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity.

Kawai H, Lopez-Pajares V, Kim MM, Wiederschain D, Yuan ZM.

Cancer Res. 2007 Jul 1;67(13):6026-30.

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