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Items: 1 to 50 of 52

1.

Pleiotropic effects of laminar flow and statins depend on the Krüppel-like factor-induced lncRNA MANTIS.

Leisegang MS, Bibli SI, Günther S, Pflüger-Müller B, Oo JA, Höper C, Seredinski S, Yekelchyk M, Schmitz-Rixen T, Schürmann C, Hu J, Looso M, Sigala F, Boon RA, Fleming I, Brandes RP.

Eur Heart J. 2019 Aug 7;40(30):2523-2533. doi: 10.1093/eurheartj/ehz393.

PMID:
31222221
2.

A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Helker CSM, Mullapudi ST, Mueller LM, Preussner J, Tunaru S, Skog O, Kwon HB, Kreuder F, Lancman JJ, Bonnavion R, Dong PDS, Looso M, Offermanns S, Korsgren O, Spagnoli FM, Stainier DYR.

Development. 2019 Jul 24;146(14). pii: dev172569. doi: 10.1242/dev.172569.

PMID:
31142539
3.

Connect-four: genomic analyses of regenerating stem cells identifies zygotic Dux factors as tumor initiators.

Preussner J, Zhong J, Looso M, Braun T, Kim J.

Mol Cell Oncol. 2019 Feb 8;6(2):1565469. doi: 10.1080/23723556.2019.1565469. eCollection 2019.

PMID:
31131298
4.

MARMoSET - Extracting Publication-ready Mass Spectrometry Metadata from RAW Files.

Kiweler M, Looso M, Graumann J.

Mol Cell Proteomics. 2019 Aug;18(8):1700-1702. doi: 10.1074/mcp.TIR119.001505. Epub 2019 May 16.

5.

Next-generation sequencing for hypothesis-free genomic detection of invasive tropical infections in poly-microbially contaminated, formalin-fixed, paraffin-embedded tissue samples - a proof-of-principle assessment.

Frickmann H, Künne C, Hagen RM, Podbielski A, Normann J, Poppert S, Looso M, Kreikemeyer B.

BMC Microbiol. 2019 Apr 8;19(1):75. doi: 10.1186/s12866-019-1448-0.

6.

Author Correction: Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system.

Kaur H, Carvalho J, Looso M, Singh P, Chennupati R, Preussner J, Günther S, Albarrán-Juárez J, Tischner D, Classen S, Offermanns S, Wettschureck N.

Nat Commun. 2019 Mar 28;10(1):1448. doi: 10.1038/s41467-019-09334-3.

7.

The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.

Leisegang MS, Gu L, Preussner J, Günther S, Hitzel J, Ratiu C, Weigert A, Chen W, Schwarz EC, Looso M, Fork C, Brandes RP.

FEBS Lett. 2019 Mar;593(5):487-498. doi: 10.1002/1873-3468.13337. Epub 2019 Feb 27.

PMID:
30758047
8.

aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability.

Riddell M, Nakayama A, Hikita T, Mirzapourshafiyi F, Kawamura T, Pasha A, Li M, Masuzawa M, Looso M, Steinbacher T, Ebnet K, Potente M, Hirose T, Ohno S, Fleming I, Gattenlöhner S, Aung PP, Phung T, Yamasaki O, Yanagi T, Umemura H, Nakayama M.

Nat Commun. 2018 Dec 17;9(1):5357. doi: 10.1038/s41467-018-07739-0.

9.

WIlsON: Web-based Interactive Omics VisualizatioN.

Schultheis H, Kuenne C, Preussner J, Wiegandt R, Fust A, Bentsen M, Looso M.

Bioinformatics. 2019 Mar 15;35(6):1055-1057. doi: 10.1093/bioinformatics/bty711.

10.

Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement.

Jia G, Preussner J, Chen X, Guenther S, Yuan X, Yekelchyk M, Kuenne C, Looso M, Zhou Y, Teichmann S, Braun T.

Nat Commun. 2018 Nov 19;9(1):4877. doi: 10.1038/s41467-018-07307-6.

11.

Oncogenic Amplification of Zygotic Dux Factors in Regenerating p53-Deficient Muscle Stem Cells Defines a Molecular Cancer Subtype.

Preussner J, Zhong J, Sreenivasan K, Günther S, Engleitner T, Künne C, Glatzel M, Rad R, Looso M, Braun T, Kim J.

Cell Stem Cell. 2018 Dec 6;23(6):794-805.e4. doi: 10.1016/j.stem.2018.10.011. Epub 2018 Nov 15.

PMID:
30449715
12.

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR.

Nat Commun. 2018 Nov 2;9(1):4600. doi: 10.1038/s41467-018-06833-7.

13.

The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis.

Yin W, Kim HT, Wang S, Gunawan F, Wang L, Kishimoto K, Zhong H, Roman D, Preussner J, Guenther S, Graef V, Buettner C, Grohmann B, Looso M, Morimoto M, Mardon G, Offermanns S, Stainier DYR.

Nat Commun. 2018 Jul 19;9(1):2815. doi: 10.1038/s41467-018-05043-5.

14.

Long noncoding RNA LISPR1 is required for S1P signaling and endothelial cell function.

Josipovic I, Pflüger B, Fork C, Vasconez AE, Oo JA, Hitzel J, Seredinski S, Gamen E, Heringdorf DMZ, Chen W, Looso M, Pullamsetti SS, Brandes RP, Leisegang MS.

J Mol Cell Cardiol. 2018 Mar;116:57-68. doi: 10.1016/j.yjmcc.2018.01.015. Epub 2018 Feb 3.

PMID:
29408197
15.

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice.

Rezende F, Moll F, Walter M, Helfinger V, Hahner F, Janetzko P, Ringel C, Weigert A, Fleming I, Weissmann N, Kuenne C, Looso M, Rieger MA, Nawroth P, Fleming T, Brandes RP, Schröder K.

Redox Biol. 2018 May;15:12-21. doi: 10.1016/j.redox.2017.11.014. Epub 2017 Nov 22.

16.

Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment.

Worzfeld T, Finkernagel F, Reinartz S, Konzer A, Adhikary T, Nist A, Stiewe T, Wagner U, Looso M, Graumann J, Müller R.

Mol Cell Proteomics. 2018 Feb;17(2):270-289. doi: 10.1074/mcp.RA117.000400. Epub 2017 Nov 15.

17.

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension.

Hautefort A, Chesné J, Preussner J, Pullamsetti SS, Tost J, Looso M, Antigny F, Girerd B, Riou M, Eddahibi S, Deleuze JF, Seeger W, Fadel E, Simonneau G, Montani D, Humbert M, Perros F.

Oncotarget. 2017 May 19;8(32):52995-53016. doi: 10.18632/oncotarget.18031. eCollection 2017 Aug 8.

18.

Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.

Tischner D, Grimm M, Kaur H, Staudenraus D, Carvalho J, Looso M, Günther S, Wanke F, Moos S, Siller N, Breuer J, Schwab N, Zipp F, Waisman A, Kurschus FC, Offermanns S, Wettschureck N.

JCI Insight. 2017 Aug 3;2(15). pii: 95063. doi: 10.1172/jci.insight.95063. eCollection 2017 Aug 3.

19.

Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration.

Lai SL, Marín-Juez R, Moura PL, Kuenne C, Lai JKH, Tsedeke AT, Guenther S, Looso M, Stainier DY.

Elife. 2017 Jun 20;6. pii: e25605. doi: 10.7554/eLife.25605.

20.

Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system.

Kaur H, Carvalho J, Looso M, Singh P, Chennupati R, Preussner J, Günther S, Albarrán-Juárez J, Tischner D, Classen S, Offermanns S, Wettschureck N.

Nat Commun. 2017 Jun 16;8:15700. doi: 10.1038/ncomms15700. Erratum in: Nat Commun. 2019 Mar 28;10(1):1448.

21.

UROPA: a tool for Universal RObust Peak Annotation.

Kondili M, Fust A, Preussner J, Kuenne C, Braun T, Looso M.

Sci Rep. 2017 Jun 1;7(1):2593. doi: 10.1038/s41598-017-02464-y.

22.

Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells.

Rauschert I, Aldunate F, Preussner J, Arocena-Sutz M, Peraza V, Looso M, Benech JC, Agrelo R.

PLoS One. 2017 Apr 19;12(4):e0175953. doi: 10.1371/journal.pone.0175953. eCollection 2017.

23.

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.

Leisegang MS, Fork C, Josipovic I, Richter FM, Preussner J, Hu J, Miller MJ, Epah J, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ Jr, Brandes RP.

Circulation. 2017 Jul 4;136(1):65-79. doi: 10.1161/CIRCULATIONAHA.116.026991. Epub 2017 Mar 28.

24.

A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.

Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, Krasel C, Heil D, Krishnan RK, Santoni MJ, Borg JP, Bünemann M, Offermanns S, Swiercz JM, Worzfeld T.

J Cell Biol. 2017 Jan 2;216(1):199-215. doi: 10.1083/jcb.201602002. Epub 2016 Dec 22.

25.

LimiTT: link miRNAs to targets.

Bayer J, Kuenne C, Preussner J, Looso M.

BMC Bioinformatics. 2016 May 11;17(1):210. doi: 10.1186/s12859-016-1070-1.

26.

Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice.

Kaur H, Takefuji M, Ngai CY, Carvalho J, Bayer J, Wietelmann A, Poetsch A, Hoelper S, Conway SJ, Möllmann H, Looso M, Troidl C, Offermanns S, Wettschureck N.

Circ Res. 2016 Jun 10;118(12):1906-17. doi: 10.1161/CIRCRESAHA.116.308643. Epub 2016 May 2. Erratum in: Circ Res. 2016 Sep 16;119(7):e109.

PMID:
27140435
27.

PAFAH1B1 and the lncRNA NONHSAT073641 maintain an angiogenic phenotype in human endothelial cells.

Josipovic I, Fork C, Preussner J, Prior KK, Iloska D, Vasconez AE, Labocha S, Angioni C, Thomas D, Ferreirós N, Looso M, Pullamsetti SS, Geisslinger G, Steinhilber D, Brandes RP, Leisegang MS.

Acta Physiol (Oxf). 2016 Sep;218(1):13-27. doi: 10.1111/apha.12700. Epub 2016 May 20.

PMID:
27124368
28.

The Histone Demethylase PHF8 Is Essential for Endothelial Cell Migration.

Gu L, Hitzel J, Moll F, Kruse C, Malik RA, Preussner J, Looso M, Leisegang MS, Steinhilber D, Brandes RP, Fork C.

PLoS One. 2016 Jan 11;11(1):e0146645. doi: 10.1371/journal.pone.0146645. eCollection 2016.

29.

ADMIRE: analysis and visualization of differential methylation in genomic regions using the Infinium HumanMethylation450 Assay.

Preussner J, Bayer J, Kuenne C, Looso M.

Epigenetics Chromatin. 2015 Dec 1;8:51. doi: 10.1186/s13072-015-0045-1. eCollection 2015.

30.

RNA-Seq analysis of isolated satellite cells in Prmt5 deficient mice.

Kuenne C, Guenther S, Looso M, Zhang T, Krueger M, Zhou Y, Braun T, Kim J.

Genom Data. 2015 Jun 3;5:122-5. doi: 10.1016/j.gdata.2015.05.013. eCollection 2015 Sep.

31.

The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.

Caputo L, Witzel HR, Kolovos P, Cheedipudi S, Looso M, Mylona A, van IJcken WF, Laugwitz KL, Evans SM, Braun T, Soler E, Grosveld F, Dobreva G.

Cell Stem Cell. 2015 Sep 3;17(3):287-99. doi: 10.1016/j.stem.2015.08.007. Epub 2015 Aug 27.

32.

High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX.

Singh I, Ozturk N, Cordero J, Mehta A, Hasan D, Cosentino C, Sebastian C, Krüger M, Looso M, Carraro G, Bellusci S, Seeger W, Braun T, Mostoslavsky R, Barreto G.

Cell Res. 2015 Jul;25(7):837-50. doi: 10.1038/cr.2015.67. Epub 2015 Jun 5.

33.

Prmt5 is a regulator of muscle stem cell expansion in adult mice.

Zhang T, Günther S, Looso M, Künne C, Krüger M, Kim J, Zhou Y, Braun T.

Nat Commun. 2015 Jun 1;6:7140. doi: 10.1038/ncomms8140.

34.

Identification of the orphan gene Prod 1 in basal and other salamander families.

Geng J, Gates PB, Kumar A, Guenther S, Garza-Garcia A, Kuenne C, Zhang P, Looso M, Brockes JP.

Evodevo. 2015 Apr 11;6:9. doi: 10.1186/s13227-015-0006-6. eCollection 2015.

35.

Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate.

Krishnan RK, Nolte H, Sun T, Kaur H, Sreenivasan K, Looso M, Offermanns S, Krüger M, Swiercz JM.

Nat Commun. 2015 Apr 7;6:6658. doi: 10.1038/ncomms7658.

36.

A Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration.

Petersen HO, Höger SK, Looso M, Lengfeld T, Kuhn A, Warnken U, Nishimiya-Fujisawa C, Schnölzer M, Krüger M, Özbek S, Simakov O, Holstein TW.

Mol Biol Evol. 2015 Aug;32(8):1928-47. doi: 10.1093/molbev/msv079. Epub 2015 Apr 3.

37.

Data mining in newt-omics, the repository for omics data from the newt.

Looso M, Braun T.

Methods Mol Biol. 2015;1290:337-51. doi: 10.1007/978-1-4939-2495-0_26.

PMID:
25740498
38.

Molecular signatures that correlate with induction of lens regeneration in newts: lessons from proteomic analysis.

Sousounis K, Bhavsar R, Looso M, Krüger M, Beebe J, Braun T, Tsonis PA.

Hum Genomics. 2014 Dec 11;8:22. doi: 10.1186/s40246-014-0022-y.

39.

RBM24 is a major regulator of muscle-specific alternative splicing.

Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T.

Dev Cell. 2014 Oct 13;31(1):87-99. doi: 10.1016/j.devcel.2014.08.025.

40.

MIRPIPE: quantification of microRNAs in niche model organisms.

Kuenne C, Preussner J, Herzog M, Braun T, Looso M.

Bioinformatics. 2014 Dec 1;30(23):3412-3. doi: 10.1093/bioinformatics/btu573. Epub 2014 Aug 26.

42.

Integrative "omics"-approach discovers dynamic and regulatory features of bacterial stress responses.

Berghoff BA, Konzer A, Mank NN, Looso M, Rische T, Förstner KU, Krüger M, Klug G.

PLoS Genet. 2013 Jun;9(6):e1003576. doi: 10.1371/journal.pgen.1003576. Epub 2013 Jun 20.

43.

Transcriptome analysis of newt lens regeneration reveals distinct gradients in gene expression patterns.

Sousounis K, Looso M, Maki N, Ivester CJ, Braun T, Tsonis PA.

PLoS One. 2013 Apr 16;8(4):e61445. doi: 10.1371/journal.pone.0061445. Print 2013.

44.

A de novo assembly of the newt transcriptome combined with proteomic validation identifies new protein families expressed during tissue regeneration.

Looso M, Preussner J, Sousounis K, Bruckskotten M, Michel CS, Lignelli E, Reinhardt R, Höffner S, Krüger M, Tsonis PA, Borchardt T, Braun T.

Genome Biol. 2013 Feb 20;14(2):R16. doi: 10.1186/gb-2013-14-2-r16.

45.

A microarray analysis of gene expression patterns during early phases of newt lens regeneration.

Sousounis K, Michel CS, Bruckskotten M, Maki N, Borchardt T, Braun T, Looso M, Tsonis PA.

Mol Vis. 2013;19:135-45. Epub 2013 Jan 28.

46.

Spiked-in pulsed in vivo labeling identifies a new member of the CCN family in regenerating newt hearts.

Looso M, Michel CS, Konzer A, Bruckskotten M, Borchardt T, Krüger M, Braun T.

J Proteome Res. 2012 Sep 7;11(9):4693-704. doi: 10.1021/pr300521p. Epub 2012 Aug 27.

PMID:
22891955
47.

ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis.

Worzfeld T, Swiercz JM, Looso M, Straub BK, Sivaraj KK, Offermanns S.

J Clin Invest. 2012 Apr;122(4):1296-305. doi: 10.1172/JCI60568. Epub 2012 Mar 1.

48.

On marathons and Sprints: an integrated quantitative proteomics and transcriptomics analysis of differences between slow and fast muscle fibers.

Drexler HC, Ruhs A, Konzer A, Mendler L, Bruckskotten M, Looso M, Günther S, Boettger T, Krüger M, Braun T.

Mol Cell Proteomics. 2012 Jun;11(6):M111.010801. doi: 10.1074/mcp.M111.010801. Epub 2011 Dec 30.

49.

Newt-omics: a comprehensive repository for omics data from the newt Notophthalmus viridescens.

Bruckskotten M, Looso M, Reinhardt R, Braun T, Borchardt T.

Nucleic Acids Res. 2012 Jan;40(Database issue):D895-900. doi: 10.1093/nar/gkr873. Epub 2011 Oct 27.

50.

PCA2GO: a new multivariate statistics based method to identify highly expressed GO-Terms.

Bruckskotten M, Looso M, Cemiĉ F, Konzer A, Hemberger J, Krüger M, Braun T.

BMC Bioinformatics. 2010 Jun 21;11:336. doi: 10.1186/1471-2105-11-336.

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