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Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis.

Ramos-Ibeas P, Sang F, Zhu Q, Tang WWC, Withey S, Klisch D, Wood L, Loose M, Surani MA, Alberio R.

Nat Commun. 2019 Jan 30;10(1):500. doi: 10.1038/s41467-019-08387-8.


Reply to 'Errors in long-read assemblies can critically affect protein prediction'.

Koren S, Phillippy AM, Simpson JT, Loman NJ, Loose M.

Nat Biotechnol. 2019 Feb;37(2):127-128. doi: 10.1038/s41587-018-0005-y. No abstract available.


Examining diabetic heel ulcers through an ecological lens: microbial community dynamics associated with healing and infection.

Sloan TJ, Turton JC, Tyson J, Musgrove A, Fleming VM, Lister MM, Loose MW, Sockett RE, Diggle M, Game FL, Jeffcoate W.

J Med Microbiol. 2019 Feb;68(2):230-240. doi: 10.1099/jmm.0.000907. Epub 2019 Jan 9.


Selection of egg peptide biomarkers in processed food products by high resolution mass spectrometry.

Gavage M, Van Vlierberghe K, Van Poucke C, De Loose M, Gevaert K, Dieu M, Renard P, Arnould T, Gillard N.

J Chromatogr A. 2019 Jan 11;1584:115-125. doi: 10.1016/j.chroma.2018.11.036. Epub 2018 Nov 20.


BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files.

Payne A, Holmes N, Rakyan V, Loose M.

Bioinformatics. 2018 Nov 20. doi: 10.1093/bioinformatics/bty841. [Epub ahead of print]



Alejandro JI, Gilliland M, Loose M.

Nursing. 2018 Dec;48(12):8. doi: 10.1097/01.NURSE.0000547730.07729.a9. No abstract available.


Serum bactericidal activity of colistin and azidothymidine combinations against mcr-1-positive colistin-resistant Escherichia coli.

Loose M, Naber KG, Hu Y, Coates A, Wagenlehner FME.

Int J Antimicrob Agents. 2018 Dec;52(6):783-789. doi: 10.1016/j.ijantimicag.2018.08.010. Epub 2018 Aug 21.


Inulin chain length modification using a transgenic approach opening new perspectives for chicory.

Maroufi A, Karimi M, Mehdikhanlou K, De Loose M.

3 Biotech. 2018 Aug;8(8):349. doi: 10.1007/s13205-018-1377-x. Epub 2018 Jul 31.


Cognitive phenotypes of sequential staging in amyotrophic lateral sclerosis.

Lulé D, Böhm S, Müller HP, Aho-Özhan H, Keller J, Gorges M, Loose M, Weishaupt JH, Uttner I, Pinkhardt E, Kassubek J, Del Tredici K, Braak H, Abrahams S, Ludolph AC.

Cortex. 2018 Apr;101:163-171. doi: 10.1016/j.cortex.2018.01.004. Epub 2018 Jan 31.


Nanopore sequencing and assembly of a human genome with ultra-long reads.

Jain M, Koren S, Miga KH, Quick J, Rand AC, Sasani TA, Tyson JR, Beggs AD, Dilthey AT, Fiddes IT, Malla S, Marriott H, Nieto T, O'Grady J, Olsen HE, Pedersen BS, Rhie A, Richardson H, Quinlan AR, Snutch TP, Tee L, Paten B, Phillippy AM, Simpson JT, Loman NJ, Loose M.

Nat Biotechnol. 2018 Apr;36(4):338-345. doi: 10.1038/nbt.4060. Epub 2018 Jan 29.


Development and validation of a standardized double-blind, placebo-controlled food challenge matrix for raw hazelnuts.

Vandekerckhove M, Van Droogenbroeck B, De Loose M, Coudijzer K, Coppens M, Gevaert P, Lapeere H.

Clin Transl Allergy. 2018 Jan 26;8:3. doi: 10.1186/s13601-017-0181-8. eCollection 2018.


Virtual Genome Walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence.

Evans T, Johnson AD, Loose M.

Sci Rep. 2018 Jan 12;8(1):618. doi: 10.1038/s41598-017-19128-6. Erratum in: Sci Rep. 2018 Apr 13;8(1):6148.


Urinary concentrations and antimicrobial activity of tobramycin in healthy volunteers receiving a single oral dose of a novel formulation for improved absorption.

Loose M, Naber KG, Shields P, Reinhart H, Wagenlehner FME.

Int J Antimicrob Agents. 2018 Mar;51(3):422-426. doi: 10.1016/j.ijantimicag.2017.11.004. Epub 2017 Nov 20.


The potential impact of nanopore sequencing on human genetics.

Loose MW.

Hum Mol Genet. 2017 Oct 1;26(R2):R202-R207. doi: 10.1093/hmg/ddx287. Review.


MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry.

Jain M, Tyson JR, Loose M, Ip CLC, Eccles DA, O'Grady J, Malla S, Leggett RM, Wallerman O, Jansen HJ, Zalunin V, Birney E, Brown BL, Snutch TP, Olsen HE; MinION Analysis and Reference Consortium.

F1000Res. 2017 May 31;6:760. doi: 10.12688/f1000research.11354.1. eCollection 2017.


Development of an LC-MS/MS method for the detection of traces of peanut allergens in chili pepper.

Vandekerckhove M, Van Droogenbroeck B, De Loose M, Taverniers I, Daeseleire E, Gevaert P, Lapeere H, Van Poucke C.

Anal Bioanal Chem. 2017 Sep;409(22):5201-5207. doi: 10.1007/s00216-017-0506-4. Epub 2017 Jul 26.


Cell Polarity in Cerebral Cortex Development-Cellular Architecture Shaped by Biochemical Networks.

Hansen AH, Duellberg C, Mieck C, Loose M, Hippenmeyer S.

Front Cell Neurosci. 2017 Jun 28;11:176. doi: 10.3389/fncel.2017.00176. eCollection 2017. Review.


Functional reorganization during cognitive function tasks in patients with amyotrophic lateral sclerosis.

Keller J, Böhm S, Aho-Özhan HEA, Loose M, Gorges M, Kassubek J, Uttner I, Abrahams S, Ludolph AC, Lulé D.

Brain Imaging Behav. 2018 Jun;12(3):771-784. doi: 10.1007/s11682-017-9738-3.


Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.

Quick J, Grubaugh ND, Pullan ST, Claro IM, Smith AD, Gangavarapu K, Oliveira G, Robles-Sikisaka R, Rogers TF, Beutler NA, Burton DR, Lewis-Ximenez LL, de Jesus JG, Giovanetti M, Hill SC, Black A, Bedford T, Carroll MW, Nunes M, Alcantara LC Jr, Sabino EC, Baylis SA, Faria NR, Loose M, Simpson JT, Pybus OG, Andersen KG, Loman NJ.

Nat Protoc. 2017 Jun;12(6):1261-1276. doi: 10.1038/nprot.2017.066. Epub 2017 May 24.


Establishment and cryptic transmission of Zika virus in Brazil and the Americas.

Faria NR, Quick J, Claro IM, Thézé J, de Jesus JG, Giovanetti M, Kraemer MUG, Hill SC, Black A, da Costa AC, Franco LC, Silva SP, Wu CH, Raghwani J, Cauchemez S, du Plessis L, Verotti MP, de Oliveira WK, Carmo EH, Coelho GE, Santelli ACFS, Vinhal LC, Henriques CM, Simpson JT, Loose M, Andersen KG, Grubaugh ND, Somasekar S, Chiu CY, Muñoz-Medina JE, Gonzalez-Bonilla CR, Arias CF, Lewis-Ximenez LL, Baylis SA, Chieppe AO, Aguiar SF, Fernandes CA, Lemos PS, Nascimento BLS, Monteiro HAO, Siqueira IC, de Queiroz MG, de Souza TR, Bezerra JF, Lemos MR, Pereira GF, Loudal D, Moura LC, Dhalia R, França RF, Magalhães T, Marques ET Jr, Jaenisch T, Wallau GL, de Lima MC, Nascimento V, de Cerqueira EM, de Lima MM, Mascarenhas DL, Neto JPM, Levin AS, Tozetto-Mendoza TR, Fonseca SN, Mendes-Correa MC, Milagres FP, Segurado A, Holmes EC, Rambaut A, Bedford T, Nunes MRT, Sabino EC, Alcantara LCJ, Loman NJ, Pybus OG.

Nature. 2017 Jun 15;546(7658):406-410. doi: 10.1038/nature22401. Epub 2017 May 24.


Reconstitution of Protein Dynamics Involved in Bacterial Cell Division.

Loose M, Zieske K, Schwille P.

Subcell Biochem. 2017;84:419-444. doi: 10.1007/978-3-319-53047-5_15.


An integrated strategy combining DNA walking and NGS to detect GMOs.

Fraiture MA, Herman P, Papazova N, De Loose M, Deforce D, Ruttink T, Roosens NH.

Food Chem. 2017 Oct 1;232:351-358. doi: 10.1016/j.foodchem.2017.03.067. Epub 2017 Mar 18.


How Can We Better Detect Unauthorized GMOs in Food and Feed Chains?

Fraiture MA, Herman P, De Loose M, Debode F, Roosens NH.

Trends Biotechnol. 2017 Jun;35(6):508-517. doi: 10.1016/j.tibtech.2017.03.002. Epub 2017 Mar 24. Review.


Same-Day Diagnostic and Surveillance Data for Tuberculosis via Whole-Genome Sequencing of Direct Respiratory Samples.

Votintseva AA, Bradley P, Pankhurst L, Del Ojo Elias C, Loose M, Nilgiriwala K, Chatterjee A, Smith EG, Sanderson N, Walker TM, Morgan MR, Wyllie DH, Walker AS, Peto TEA, Crook DW, Iqbal Z.

J Clin Microbiol. 2017 May;55(5):1285-1298. doi: 10.1128/JCM.02483-16. Epub 2017 Mar 8.


Single-molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers.

Baranova N, Loose M.

Methods Cell Biol. 2017;137:355-370. doi: 10.1016/bs.mcb.2016.03.036. Epub 2016 Jul 11.


Application of highly portable MinION nanopore sequencing technology for the monitoring of nosocomial tuberculosis infection.

Bates M, Polepole P, Kapata N, Loose M, O'Grady J.

Int J Mycobacteriol. 2016 Dec;5 Suppl 1:S24. doi: 10.1016/j.ijmyco.2016.10.035. Epub 2016 Nov 23.


The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit.

Lucas R, Yue Q, Alli A, Duke BJ, Al-Khalili O, Thai TL, Hamacher J, Sridhar S, Lebedyeva I, Su H, Tzotzos S, Fischer B, Gameiro AF, Loose M, Chakraborty T, Shabbir W, Aufy M, Lemmens-Gruber R, Eaton DC, Czikora I.

J Biol Chem. 2016 Nov 4;291(45):23440-23451. Epub 2016 Sep 19.


Real-time selective sequencing using nanopore technology.

Loose M, Malla S, Stout M.

Nat Methods. 2016 Sep;13(9):751-4. doi: 10.1038/nmeth.3930. Epub 2016 Jul 25.


Age and education-matched cut-off scores for the revised German/Swiss-German version of ECAS.

Loose M, Burkhardt C, Aho-Özhan H, Keller J, Abdulla S, Böhm S, Kollewe K, Uttner I, Abrahams S, Petri S, Weber M, Ludolph AC, Lulé D.

Amyotroph Lateral Scler Frontotemporal Degener. 2016 Jul-Aug;17(5-6):374-6. doi: 10.3109/21678421.2016.1162814. Epub 2016 Mar 30.


Multicellular Mathematical Modelling of Mesendoderm Formation in Amphibians.

Brown LE, Middleton AM, King JR, Loose M.

Bull Math Biol. 2016 Mar;78(3):436-67. doi: 10.1007/s11538-016-0150-8. Epub 2016 Mar 2.


Diverse roles of endoplasmic reticulum stress sensors in bacterial infection.

Pillich H, Loose M, Zimmer KP, Chakraborty T.

Mol Cell Pediatr. 2016 Dec;3(1):9. doi: 10.1186/s40348-016-0037-7. Epub 2016 Feb 16.


MinION Analysis and Reference Consortium: Phase 1 data release and analysis.

Ip CLC, Loose M, Tyson JR, de Cesare M, Brown BL, Jain M, Leggett RM, Eccles DA, Zalunin V, Urban JM, Piazza P, Bowden RJ, Paten B, Mwaigwisya S, Batty EM, Simpson JT, Snutch TP, Birney E, Buck D, Goodwin S, Jansen HJ, O'Grady J, Olsen HE; MinION Analysis and Reference Consortium.

F1000Res. 2015 Oct 15;4:1075. doi: 10.12688/f1000research.7201.1. eCollection 2015.


AlignWise: a tool for identifying protein-coding sequence and correcting frame-shifts.

Evans T, Loose M.

BMC Bioinformatics. 2015 Nov 9;16:376. doi: 10.1186/s12859-015-0813-8.


Current and new approaches in GMO detection: challenges and solutions.

Fraiture MA, Herman P, Taverniers I, De Loose M, Deforce D, Roosens NH.

Biomed Res Int. 2015;2015:392872. doi: 10.1155/2015/392872. Epub 2015 Oct 15. Review.


Fisetin Protects Against Listeria monocytogenes Infection by Reducing the Production of Listeriolysin O.

Loose M, Pillich H, Chakraborty T.

J Infect Dis. 2016 Feb 15;213(4):684-5. doi: 10.1093/infdis/jiv437. Epub 2015 Sep 7. No abstract available.


Statistical framework for detection of genetically modified organisms based on Next Generation Sequencing.

Willems S, Fraiture MA, Deforce D, De Keersmaecker SC, De Loose M, Ruttink T, Herman P, Van Nieuwerburgh F, Roosens N.

Food Chem. 2016 Feb 1;192:788-98. doi: 10.1016/j.foodchem.2015.07.074. Epub 2015 Jul 21.


Integrated DNA walking system to characterize a broad spectrum of GMOs in food/feed matrices.

Fraiture MA, Herman P, Lefèvre L, Taverniers I, De Loose M, Deforce D, Roosens NH.

BMC Biotechnol. 2015 Aug 14;15:76. doi: 10.1186/s12896-015-0191-3.


Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins.

Nguyen PA, Field CM, Groen AC, Mitchison TJ, Loose M.

Methods Cell Biol. 2015;128:223-241. doi: 10.1016/bs.mcb.2015.01.007. Epub 2015 Apr 8.


[Incidence of puerperal diseases during the first 10 days after foaling in the mare].

Hussein HA, Loose M, Wehrend A.

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2015;43(3):150-3. doi: 10.15653/TPG-141001. Epub 2015 May 11. German.


A disruptive sequencer meets disruptive publishing.

Loman N, Goodwin S, Jansen H, Loose M.

F1000Res. 2015 Oct 15;4:1074. doi: 10.12688/f1000research.7229.1. eCollection 2015.


Validation of a sensitive DNA walking strategy to characterise unauthorised GMOs using model food matrices mimicking common rice products.

Fraiture MA, Herman P, Taverniers I, De Loose M, Van Nieuwerburgh F, Deforce D, Roosens NH.

Food Chem. 2015 Apr 15;173:1259-65. doi: 10.1016/j.foodchem.2014.09.148. Epub 2014 Oct 5.


A comparative study between spiral-filter press and belt press implemented in a cloudy apple juice production process.

De Paepe D, Coudijzer K, Noten B, Valkenborg D, Servaes K, De Loose M, Diels L, Voorspoels S, Van Droogenbroeck B.

Food Chem. 2015 Apr 15;173:986-96. doi: 10.1016/j.foodchem.2014.10.019. Epub 2014 Oct 12.


Pilot-scale production of cloudy juice from low-quality pear fruit under low-oxygen conditions.

De Paepe D, Coudijzer K, Noten B, Valkenborg D, Servaes K, De Loose M, Diels L, Voorspoels S, Van Droogenbroeck B.

Food Chem. 2015 Apr 15;173:827-37. doi: 10.1016/j.foodchem.2014.10.018. Epub 2014 Oct 12.


Spatial organization of cytokinesis signaling reconstituted in a cell-free system.

Nguyen PA, Groen AC, Loose M, Ishihara K, Wühr M, Field CM, Mitchison TJ.

Science. 2014 Oct 10;346(6206):244-7. doi: 10.1126/science.1256773.


Pneumococcal hydrogen peroxide-induced stress signaling regulates inflammatory genes.

Loose M, Hudel M, Zimmer KP, Garcia E, Hammerschmidt S, Lucas R, Chakraborty T, Pillich H.

J Infect Dis. 2015 Jan 15;211(2):306-16. doi: 10.1093/infdis/jiu428. Epub 2014 Sep 2.


Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos.

Chatfield J, O'Reilly MA, Bachvarova RF, Ferjentsik Z, Redwood C, Walmsley M, Patient R, Loose M, Johnson AD.

Development. 2014 Jun;141(12):2429-40. doi: 10.1242/dev.105346.


Transient accumulation of 5-carboxylcytosine indicates involvement of active demethylation in lineage specification of neural stem cells.

Wheldon LM, Abakir A, Ferjentsik Z, Dudnakova T, Strohbuecker S, Christie D, Dai N, Guan S, Foster JM, Corrêa IR Jr, Loose M, Dixon JE, Sottile V, Johnson AD, Ruzov A.

Cell Rep. 2014 Jun 12;7(5):1353-1361. doi: 10.1016/j.celrep.2014.05.003. Epub 2014 May 29.


Thermal degradation of cloudy apple juice phenolic constituents.

De Paepe D, Valkenborg D, Coudijzer K, Noten B, Servaes K, De Loose M, Voorspoels S, Diels L, Van Droogenbroeck B.

Food Chem. 2014 Nov 1;162:176-85. doi: 10.1016/j.foodchem.2014.04.005. Epub 2014 Apr 13.


Acquisition of germ plasm accelerates vertebrate evolution.

Evans T, Wade CM, Chapman FA, Johnson AD, Loose M.

Science. 2014 Apr 11;344(6180):200-3. doi: 10.1126/science.1249325.

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