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Stochastic activation and bistability in a Rab GTPase regulatory network.

Bezeljak U, Loya H, Kaczmarek B, Saunders TE, Loose M.

Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6540-6549. doi: 10.1073/pnas.1921027117. Epub 2020 Mar 11.


Effect of Different Media on the Bactericidal Activity of Colistin and on the Synergistic Combination With Azidothymidine Against mcr-1-Positive Colistin-Resistant Escherichia coli.

Loose M, Naber KG, Coates A, Wagenlehner FME, Hu Y.

Front Microbiol. 2020 Jan 29;11:54. doi: 10.3389/fmicb.2020.00054. eCollection 2020.


Diffusion and capture permits dynamic coupling between treadmilling FtsZ filaments and cell division proteins.

Baranova N, Radler P, Hernández-Rocamora VM, Alfonso C, López-Pelegrín M, Rivas G, Vollmer W, Loose M.

Nat Microbiol. 2020 Mar;5(3):407-417. doi: 10.1038/s41564-019-0657-5. Epub 2020 Jan 20.


Critical review on proteotypic peptide marker tracing for six allergenic ingredients in incurred foods by mass spectrometry.

Pilolli R, Nitride C, Gillard N, Huet AC, van Poucke C, de Loose M, Tranquet O, Larré C, Adel-Patient K, Bernard H, Mills ENC, Monaci L.

Food Res Int. 2020 Feb;128:108747. doi: 10.1016/j.foodres.2019.108747. Epub 2019 Nov 13. Review.


Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA.

Caldas P, López-Pelegrín M, Pearce DJG, Budanur NB, Brugués J, Loose M.

Nat Commun. 2019 Dec 17;10(1):5744. doi: 10.1038/s41467-019-13702-4.


Author Correction: Nanopore native RNA sequencing of a human poly(A) transcriptome.

Workman RE, Tang AD, Tang PS, Jain M, Tyson JR, Razaghi R, Zuzarte PC, Gilpatrick T, Payne A, Quick J, Sadowski N, Holmes N, de Jesus JG, Jones KL, Soulette CM, Snutch TP, Loman N, Paten B, Loose M, Simpson JT, Olsen HE, Brooks AN, Akeson M, Timp W.

Nat Methods. 2020 Jan;17(1):114. doi: 10.1038/s41592-019-0697-z.


[Retained placenta in mares - an analysis of 121 cases].

Schürmann C, Loose M, Failing K, Wehrend A.

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2019 Dec;47(6):373-379. doi: 10.1055/a-1019-7345. Epub 2019 Dec 6. German.


Nanopore native RNA sequencing of a human poly(A) transcriptome.

Workman RE, Tang AD, Tang PS, Jain M, Tyson JR, Razaghi R, Zuzarte PC, Gilpatrick T, Payne A, Quick J, Sadowski N, Holmes N, de Jesus JG, Jones KL, Soulette CM, Snutch TP, Loman N, Paten B, Loose M, Simpson JT, Olsen HE, Brooks AN, Akeson M, Timp W.

Nat Methods. 2019 Dec;16(12):1297-1305. doi: 10.1038/s41592-019-0617-2. Epub 2019 Nov 18. Erratum in: Nat Methods. 2020 Jan;17(1):114.


Selection of universal peptide biomarkers for the detection of the allergen hazelnut in food trough a comprehensive, high resolution mass spectrometric (HRMS) based approach.

Van Vlierberghe K, Gavage M, Dieu M, Renard P, Arnould T, Gillard N, Coudijzer K, De Loose M, Gevaert K, Van Poucke C.

Food Chem. 2020 Mar 30;309:125679. doi: 10.1016/j.foodchem.2019.125679. Epub 2019 Oct 19.


Carbapenem-Containing Combination Antibiotic Therapy against Carbapenem-Resistant Uropathogenic Enterobacteriaceae.

Loose M, Link I, Naber KG, Wagenlehner FME.

Antimicrob Agents Chemother. 2019 Dec 20;64(1). pii: e01839-19. doi: 10.1128/AAC.01839-19. Print 2019 Dec 20.


Strained-layer-superlattice-based compact thermal imager for the International Space Station.

Jhabvala M, Jennings D, Tucker C, La A, Keer B, Timmons E, Stone R, Flatley T, Cepollina F, Babu S, Lunsford A, Cassidy J, Parker D, Sundaram M, Bundas J, Squicciarini W, Finneran P, Orlowski I, Fetter C, Loose M.

Appl Opt. 2019 Jul 10;58(20):5432-5442. doi: 10.1364/AO.58.005432.


High-resolution mass spectrometry-based selection of peanut peptide biomarkers considering food processing and market type variation.

Gavage M, Van Vlierberghe K, Van Poucke C, De Loose M, Gevaert K, Dieu M, Renard P, Arnould T, Gillard N.

Food Chem. 2020 Jan 30;304:125428. doi: 10.1016/j.foodchem.2019.125428. Epub 2019 Aug 26.


An observational study on quality of life and preferences to sustain life in locked-in state.

Kuzma-Kozakiewicz M, Andersen PM, Ciecwierska K, Vázquez C, Helczyk O, Loose M, Uttner I, Ludolph AC, Lulé D.

Neurology. 2019 Sep 3;93(10):e938-e945. doi: 10.1212/WNL.0000000000008064. Epub 2019 Aug 7.


Urinary bactericidal activity of colistin and azidothymidine combinations against mcr-1-positive colistin-resistant Escherichia coli.

Loose M, Naber KG, Hu Y, Coates A, Wagenlehner FME.

Int J Antimicrob Agents. 2019 Jul;54(1):55-61. doi: 10.1016/j.ijantimicag.2019.04.011. Epub 2019 Apr 26.


Finding the Needle: Targeted Nanopore Sequencing and CRISPR-Cas9.

Loose M.

CRISPR J. 2018 Aug;1:265-267. doi: 10.1089/crispr.2018.29028.mlo. No abstract available.


Detection and Quantification of Allergens in Foods and Minimum Eliciting Doses in Food-Allergic Individuals (ThRAll).

Mills ENC, Adel-Patient K, Bernard H, De Loose M, Gillard N, Huet AC, Larré C, Nitride C, Pilolli R, Tranquet O, Pouke CV, Monaci L.

J AOAC Int. 2019 Sep 1;102(5):1346-1353. doi: 10.5740/jaoacint.19-0063. Epub 2019 Apr 2. Review.


Optimizing the Use of Zebrafish Feeding Trials for the Safety Evaluation of Genetically Modified Crops.

Gabriëls IJ, Vergauwen L, De Boevre M, Van Dongen S, Blust R, De Saeger S, Eeckhout M, De Loose M, Knapen D.

Int J Mol Sci. 2019 Mar 23;20(6). pii: E1472. doi: 10.3390/ijms20061472.


A Novel Double-Blind, Placebo-Controlled Food Challenge Matrix for Milk and Raw Egg.

Vandekerckhove M, Van Droogenbroeck B, De Loose M, Coudijzer K, Van Winckel M, Gevaert P, Lapeere H.

Int Arch Allergy Immunol. 2019;179(1):1-9. doi: 10.1159/000494622. Epub 2019 Mar 20.


Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis.

Ramos-Ibeas P, Sang F, Zhu Q, Tang WWC, Withey S, Klisch D, Wood L, Loose M, Surani MA, Alberio R.

Nat Commun. 2019 Jan 30;10(1):500. doi: 10.1038/s41467-019-08387-8.


Reply to 'Errors in long-read assemblies can critically affect protein prediction'.

Koren S, Phillippy AM, Simpson JT, Loman NJ, Loose M.

Nat Biotechnol. 2019 Feb;37(2):127-128. doi: 10.1038/s41587-018-0005-y. No abstract available.


Examining diabetic heel ulcers through an ecological lens: microbial community dynamics associated with healing and infection.

Sloan TJ, Turton JC, Tyson J, Musgrove A, Fleming VM, Lister MM, Loose MW, Sockett RE, Diggle M, Game FL, Jeffcoate W.

J Med Microbiol. 2019 Feb;68(2):230-240. doi: 10.1099/jmm.0.000907. Epub 2019 Jan 9.


Selection of egg peptide biomarkers in processed food products by high resolution mass spectrometry.

Gavage M, Van Vlierberghe K, Van Poucke C, De Loose M, Gevaert K, Dieu M, Renard P, Arnould T, Gillard N.

J Chromatogr A. 2019 Jan 11;1584:115-125. doi: 10.1016/j.chroma.2018.11.036. Epub 2018 Nov 20.


BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files.

Payne A, Holmes N, Rakyan V, Loose M.

Bioinformatics. 2019 Jul 1;35(13):2193-2198. doi: 10.1093/bioinformatics/bty841.



Alejandro JI, Gilliland M, Loose M.

Nursing. 2018 Dec;48(12):8. doi: 10.1097/01.NURSE.0000547730.07729.a9. No abstract available.


Serum bactericidal activity of colistin and azidothymidine combinations against mcr-1-positive colistin-resistant Escherichia coli.

Loose M, Naber KG, Hu Y, Coates A, Wagenlehner FME.

Int J Antimicrob Agents. 2018 Dec;52(6):783-789. doi: 10.1016/j.ijantimicag.2018.08.010. Epub 2018 Aug 21.


Inulin chain length modification using a transgenic approach opening new perspectives for chicory.

Maroufi A, Karimi M, Mehdikhanlou K, De Loose M.

3 Biotech. 2018 Aug;8(8):349. doi: 10.1007/s13205-018-1377-x. Epub 2018 Jul 31.


Cognitive phenotypes of sequential staging in amyotrophic lateral sclerosis.

Lulé D, Böhm S, Müller HP, Aho-Özhan H, Keller J, Gorges M, Loose M, Weishaupt JH, Uttner I, Pinkhardt E, Kassubek J, Del Tredici K, Braak H, Abrahams S, Ludolph AC.

Cortex. 2018 Apr;101:163-171. doi: 10.1016/j.cortex.2018.01.004. Epub 2018 Jan 31.


Nanopore sequencing and assembly of a human genome with ultra-long reads.

Jain M, Koren S, Miga KH, Quick J, Rand AC, Sasani TA, Tyson JR, Beggs AD, Dilthey AT, Fiddes IT, Malla S, Marriott H, Nieto T, O'Grady J, Olsen HE, Pedersen BS, Rhie A, Richardson H, Quinlan AR, Snutch TP, Tee L, Paten B, Phillippy AM, Simpson JT, Loman NJ, Loose M.

Nat Biotechnol. 2018 Apr;36(4):338-345. doi: 10.1038/nbt.4060. Epub 2018 Jan 29.


Development and validation of a standardized double-blind, placebo-controlled food challenge matrix for raw hazelnuts.

Vandekerckhove M, Van Droogenbroeck B, De Loose M, Coudijzer K, Coppens M, Gevaert P, Lapeere H.

Clin Transl Allergy. 2018 Jan 26;8:3. doi: 10.1186/s13601-017-0181-8. eCollection 2018.


Virtual Genome Walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence.

Evans T, Johnson AD, Loose M.

Sci Rep. 2018 Jan 12;8(1):618. doi: 10.1038/s41598-017-19128-6. Erratum in: Sci Rep. 2018 Apr 13;8(1):6148.


Urinary concentrations and antimicrobial activity of tobramycin in healthy volunteers receiving a single oral dose of a novel formulation for improved absorption.

Loose M, Naber KG, Shields P, Reinhart H, Wagenlehner FME.

Int J Antimicrob Agents. 2018 Mar;51(3):422-426. doi: 10.1016/j.ijantimicag.2017.11.004. Epub 2017 Nov 20.


The potential impact of nanopore sequencing on human genetics.

Loose MW.

Hum Mol Genet. 2017 Oct 1;26(R2):R202-R207. doi: 10.1093/hmg/ddx287. Review.


MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry.

Jain M, Tyson JR, Loose M, Ip CLC, Eccles DA, O'Grady J, Malla S, Leggett RM, Wallerman O, Jansen HJ, Zalunin V, Birney E, Brown BL, Snutch TP, Olsen HE; MinION Analysis and Reference Consortium.

F1000Res. 2017 May 31;6:760. doi: 10.12688/f1000research.11354.1. eCollection 2017.


Development of an LC-MS/MS method for the detection of traces of peanut allergens in chili pepper.

Vandekerckhove M, Van Droogenbroeck B, De Loose M, Taverniers I, Daeseleire E, Gevaert P, Lapeere H, Van Poucke C.

Anal Bioanal Chem. 2017 Sep;409(22):5201-5207. doi: 10.1007/s00216-017-0506-4. Epub 2017 Jul 26.


Cell Polarity in Cerebral Cortex Development-Cellular Architecture Shaped by Biochemical Networks.

Hansen AH, Duellberg C, Mieck C, Loose M, Hippenmeyer S.

Front Cell Neurosci. 2017 Jun 28;11:176. doi: 10.3389/fncel.2017.00176. eCollection 2017. Review.


Functional reorganization during cognitive function tasks in patients with amyotrophic lateral sclerosis.

Keller J, Böhm S, Aho-Özhan HEA, Loose M, Gorges M, Kassubek J, Uttner I, Abrahams S, Ludolph AC, Lulé D.

Brain Imaging Behav. 2018 Jun;12(3):771-784. doi: 10.1007/s11682-017-9738-3.


Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.

Quick J, Grubaugh ND, Pullan ST, Claro IM, Smith AD, Gangavarapu K, Oliveira G, Robles-Sikisaka R, Rogers TF, Beutler NA, Burton DR, Lewis-Ximenez LL, de Jesus JG, Giovanetti M, Hill SC, Black A, Bedford T, Carroll MW, Nunes M, Alcantara LC Jr, Sabino EC, Baylis SA, Faria NR, Loose M, Simpson JT, Pybus OG, Andersen KG, Loman NJ.

Nat Protoc. 2017 Jun;12(6):1261-1276. doi: 10.1038/nprot.2017.066. Epub 2017 May 24.


Establishment and cryptic transmission of Zika virus in Brazil and the Americas.

Faria NR, Quick J, Claro IM, Thézé J, de Jesus JG, Giovanetti M, Kraemer MUG, Hill SC, Black A, da Costa AC, Franco LC, Silva SP, Wu CH, Raghwani J, Cauchemez S, du Plessis L, Verotti MP, de Oliveira WK, Carmo EH, Coelho GE, Santelli ACFS, Vinhal LC, Henriques CM, Simpson JT, Loose M, Andersen KG, Grubaugh ND, Somasekar S, Chiu CY, Muñoz-Medina JE, Gonzalez-Bonilla CR, Arias CF, Lewis-Ximenez LL, Baylis SA, Chieppe AO, Aguiar SF, Fernandes CA, Lemos PS, Nascimento BLS, Monteiro HAO, Siqueira IC, de Queiroz MG, de Souza TR, Bezerra JF, Lemos MR, Pereira GF, Loudal D, Moura LC, Dhalia R, França RF, Magalhães T, Marques ET Jr, Jaenisch T, Wallau GL, de Lima MC, Nascimento V, de Cerqueira EM, de Lima MM, Mascarenhas DL, Neto JPM, Levin AS, Tozetto-Mendoza TR, Fonseca SN, Mendes-Correa MC, Milagres FP, Segurado A, Holmes EC, Rambaut A, Bedford T, Nunes MRT, Sabino EC, Alcantara LCJ, Loman NJ, Pybus OG.

Nature. 2017 Jun 15;546(7658):406-410. doi: 10.1038/nature22401. Epub 2017 May 24.


Reconstitution of Protein Dynamics Involved in Bacterial Cell Division.

Loose M, Zieske K, Schwille P.

Subcell Biochem. 2017;84:419-444. doi: 10.1007/978-3-319-53047-5_15. Review.


An integrated strategy combining DNA walking and NGS to detect GMOs.

Fraiture MA, Herman P, Papazova N, De Loose M, Deforce D, Ruttink T, Roosens NH.

Food Chem. 2017 Oct 1;232:351-358. doi: 10.1016/j.foodchem.2017.03.067. Epub 2017 Mar 18.


How Can We Better Detect Unauthorized GMOs in Food and Feed Chains?

Fraiture MA, Herman P, De Loose M, Debode F, Roosens NH.

Trends Biotechnol. 2017 Jun;35(6):508-517. doi: 10.1016/j.tibtech.2017.03.002. Epub 2017 Mar 24. Review.


Same-Day Diagnostic and Surveillance Data for Tuberculosis via Whole-Genome Sequencing of Direct Respiratory Samples.

Votintseva AA, Bradley P, Pankhurst L, Del Ojo Elias C, Loose M, Nilgiriwala K, Chatterjee A, Smith EG, Sanderson N, Walker TM, Morgan MR, Wyllie DH, Walker AS, Peto TEA, Crook DW, Iqbal Z.

J Clin Microbiol. 2017 May;55(5):1285-1298. doi: 10.1128/JCM.02483-16. Epub 2017 Mar 8.


Single-molecule measurements to study polymerization dynamics of FtsZ-FtsA copolymers.

Baranova N, Loose M.

Methods Cell Biol. 2017;137:355-370. doi: 10.1016/bs.mcb.2016.03.036. Epub 2016 Jul 11.


Application of highly portable MinION nanopore sequencing technology for the monitoring of nosocomial tuberculosis infection.

Bates M, Polepole P, Kapata N, Loose M, O'Grady J.

Int J Mycobacteriol. 2016 Dec;5 Suppl 1:S24. doi: 10.1016/j.ijmyco.2016.10.035. Epub 2016 Nov 23.


The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit.

Lucas R, Yue Q, Alli A, Duke BJ, Al-Khalili O, Thai TL, Hamacher J, Sridhar S, Lebedyeva I, Su H, Tzotzos S, Fischer B, Gameiro AF, Loose M, Chakraborty T, Shabbir W, Aufy M, Lemmens-Gruber R, Eaton DC, Czikora I.

J Biol Chem. 2016 Nov 4;291(45):23440-23451. Epub 2016 Sep 19.


Real-time selective sequencing using nanopore technology.

Loose M, Malla S, Stout M.

Nat Methods. 2016 Sep;13(9):751-4. doi: 10.1038/nmeth.3930. Epub 2016 Jul 25.


Age and education-matched cut-off scores for the revised German/Swiss-German version of ECAS.

Loose M, Burkhardt C, Aho-Özhan H, Keller J, Abdulla S, Böhm S, Kollewe K, Uttner I, Abrahams S, Petri S, Weber M, Ludolph AC, Lulé D.

Amyotroph Lateral Scler Frontotemporal Degener. 2016 Jul-Aug;17(5-6):374-6. doi: 10.3109/21678421.2016.1162814. Epub 2016 Mar 30.


Multicellular Mathematical Modelling of Mesendoderm Formation in Amphibians.

Brown LE, Middleton AM, King JR, Loose M.

Bull Math Biol. 2016 Mar;78(3):436-67. doi: 10.1007/s11538-016-0150-8. Epub 2016 Mar 2.


Diverse roles of endoplasmic reticulum stress sensors in bacterial infection.

Pillich H, Loose M, Zimmer KP, Chakraborty T.

Mol Cell Pediatr. 2016 Dec;3(1):9. doi: 10.1186/s40348-016-0037-7. Epub 2016 Feb 16.

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