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Items: 47


Demographic, Clinical, and Immunologic Correlates among a Cohort of 50 Cocaine Users Demonstrating Antineutrophil Cytoplasmic Antibodies.

Morcos MB, Lood C, Hughes GC.

J Rheumatol. 2019 May 15. pii: jrheum.180771. doi: 10.3899/jrheum.180771. [Epub ahead of print]


New Bacteriophages against Emerging Lineages ST23 and ST258 of Klebsiella pneumoniae and Efficacy Assessment in Galleria mellonella Larvae.

Thiry D, Passet V, Danis-Wlodarczyk K, Lood C, Wagemans J, De Sordi L, van Noort V, Dufour N, Debarbieux L, Mainil JG, Brisse S, Lavigne R.

Viruses. 2019 May 3;11(5). pii: E411. doi: 10.3390/v11050411.


Low plasma concentrations of apolipoprotein M are associated with disease activity and endothelial dysfunction in systemic lupus erythematosus.

Tydén H, Lood C, Jönsen A, Gullstrand B, Kahn R, Linge P, Kumaraswamy SB, Dahlbäck B, Bengtsson AA.

Arthritis Res Ther. 2019 May 2;21(1):110. doi: 10.1186/s13075-019-1890-2.


Cell-Free DNA as a Biomarker in Autoimmune Rheumatic Diseases.

Duvvuri B, Lood C.

Front Immunol. 2019 Mar 19;10:502. doi: 10.3389/fimmu.2019.00502. eCollection 2019. Review.


Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation.

Davis MA, Fairgrieve MR, Den Hartigh A, Yakovenko O, Duvvuri B, Lood C, Thomas WE, Fink SL, Gale M Jr.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5061-5070. doi: 10.1073/pnas.1818598116. Epub 2019 Feb 22.


Neutrophil extracellular traps (NETs) are increased in the alveolar spaces of patients with ventilator-associated pneumonia.

Mikacenic C, Moore R, Dmyterko V, West TE, Altemeier WA, Liles WC, Lood C.

Crit Care. 2018 Dec 27;22(1):358. doi: 10.1186/s13054-018-2290-8.


Catabolism of the groundwater micropollutant 2,6-dichlorobenzamide beyond 2,6-dichlorobenzoate is plasmid encoded in Aminobacter sp. MSH1.

T'Syen J, Raes B, Horemans B, Tassoni R, Leroy B, Lood C, van Noort V, Lavigne R, Wattiez R, Kohler HE, Springael D.

Appl Microbiol Biotechnol. 2018 Sep;102(18):7963-7979. doi: 10.1007/s00253-018-9189-9. Epub 2018 Jul 8.


Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo.

Kakabadze E, Makalatia K, Grdzelishvili N, Bakuradze N, Goderdzishvili M, Kusradze I, Phoba MF, Lunguya O, Lood C, Lavigne R, Jacobs J, Deborggraeve S, De Block T, Van Puyvelde S, Lee D, Coffey A, Sedrakyan A, Soentjens P, De Vos D, Pirnay JP, Chanishvili N.

Viruses. 2018 Apr 3;10(4). pii: E172. doi: 10.3390/v10040172.


Community-led comparative genomic and phenotypic analysis of the aquaculture pathogen Pseudomonas baetica a390T sequenced by Ion semiconductor and Nanopore technologies.

Beaton A, Lood C, Cunningham-Oakes E, MacFadyen A, Mullins AJ, Bestawy WE, Botelho J, Chevalier S, Coleman S, Dalzell C, Dolan SK, Faccenda A, Ghequire MGK, Higgins S, Kutschera A, Murray J, Redway M, Salih T, da Silva AC, Smith BA, Smits N, Thomson R, Woodcock S, Welch M, Cornelis P, Lavigne R, van Noort V, Tucker NP.

FEMS Microbiol Lett. 2018 May 1;365(9). doi: 10.1093/femsle/fny069.


The non-haemostatic role of platelets in systemic lupus erythematosus.

Linge P, Fortin PR, Lood C, Bengtsson AA, Boilard E.

Nat Rev Rheumatol. 2018 Mar 21;14(4):195-213. doi: 10.1038/nrrheum.2018.38. Review.


Canonical germinant receptor is dispensable for spore germination in Clostridium botulinum group II strain NCTC 11219.

Clauwers C, Lood C, van Noort V, Michiels CW.

Sci Rep. 2017 Nov 13;7(1):15426. doi: 10.1038/s41598-017-15839-y.


Catabolic task division between two near-isogenic subpopulations co-existing in a herbicide-degrading bacterial consortium: consequences for the interspecies consortium metabolic model.

Albers P, Lood C, Özturk B, Horemans B, Lavigne R, van Noort V, De Mot R, Marchal K, Sanchez-Rodriguez A, Springael D.

Environ Microbiol. 2018 Jan;20(1):85-96. doi: 10.1111/1462-2920.13994. Epub 2017 Dec 15.


Endothelial dysfunction is associated with activation of the type I interferon system and platelets in patients with systemic lupus erythematosus.

Tydén H, Lood C, Gullstrand B, Nielsen CT, Heegaard NHH, Kahn R, Jönsen A, Bengtsson AA.

RMD Open. 2017 Oct 25;3(2):e000508. doi: 10.1136/rmdopen-2017-000508. eCollection 2017.


TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA.

Lood C, Arve S, Ledbetter J, Elkon KB.

J Exp Med. 2017 Jul 3;214(7):2103-2119. doi: 10.1084/jem.20161512. Epub 2017 Jun 12.


Comment on: Decreased platelet size is associated with platelet activation and anti-phospholipid syndrome in systemic lupus erythematosus: reply.

Lood C, Bengtsson AA.

Rheumatology (Oxford). 2017 Aug 1;56(8):1437-1438. doi: 10.1093/rheumatology/kex216. No abstract available.


Decreased platelet size is associated with platelet activation and anti-phospholipid syndrome in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Nielsen CT, Heegaard NH, Linge P, Jönsen A, Hesselstrand R, Kahn R, Bengtsson AA.

Rheumatology (Oxford). 2017 Mar 1;56(3):408-416. doi: 10.1093/rheumatology/kew437.


Citrullination in Rheumatoid Arthritis-A Process Promoted by Neutrophil Lysis?

Gazitt T, Lood C, Elkon KB.

Rambam Maimonides Med J. 2016 Oct 31;7(4). doi: 10.5041/RMMJ.10254. Review.


Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis.

Bengtsson AA, Trygg J, Wuttge DM, Sturfelt G, Theander E, Donten M, Moritz T, Sennbro CJ, Torell F, Lood C, Surowiec I, Rännar S, Lundstedt T.

PLoS One. 2016 Jul 21;11(7):e0159384. doi: 10.1371/journal.pone.0159384. eCollection 2016.


Pro-inflammatory S100 proteins are associated with glomerulonephritis and anti-dsDNA antibodies in systemic lupus erythematosus.

Tydén H, Lood C, Gullstrand B, Jönsen A, Ivars F, Leanderson T, Bengtsson AA.

Lupus. 2017 Feb;26(2):139-149. doi: 10.1177/0961203316655208. Epub 2016 Jul 19.


Neutrophil extracellular traps as a potential source of autoantigen in cocaine-associated autoimmunity.

Lood C, Hughes GC.

Rheumatology (Oxford). 2017 Apr 1;56(4):638-643. doi: 10.1093/rheumatology/kew256.


Prasugrel 5 mg inhibits platelet P-selectin and GPIIb-IIIa expression in very elderly and non elderly: results from the GENERATIONS trial, a pharmacodynamic study in stable CAD patients.

Wagner H, Lood C, Borna C, Gidlöf O, Truedsson L, Brown P, Zhou C, Winters K, Jakubowski JA, Erlinge D.

J Thromb Thrombolysis. 2016 Oct;42(3):369-75. doi: 10.1007/s11239-016-1372-1.


Platelet-Derived S100A8/A9 and Cardiovascular Disease in Systemic Lupus Erythematosus.

Lood C, Tydén H, Gullstrand B, Jönsen A, Källberg E, Mörgelin M, Kahn R, Gunnarsson I, Leanderson T, Ivars F, Svenungsson E, Bengtsson AA.

Arthritis Rheumatol. 2016 Aug;68(8):1970-80. doi: 10.1002/art.39656.


The assessment of serum-mediated phagocytosis of necrotic material by polymorphonuclear leukocytes to diagnose and predict the clinical features of systemic lupus erythematosus: an observational longitudinal study.

Compagno M, Gullstrand B, Jacobsen S, Eilertsen GØ, Nilsson JÅ, Lood C, Jönsen A, Truedsson L, Sturfelt G, Bengtsson AA.

Arthritis Res Ther. 2016 Feb 10;18:44. doi: 10.1186/s13075-016-0941-1.


Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.

Lood C, Blanco LP, Purmalek MM, Carmona-Rivera C, De Ravin SS, Smith CK, Malech HL, Ledbetter JA, Elkon KB, Kaplan MJ.

Nat Med. 2016 Feb;22(2):146-53. doi: 10.1038/nm.4027. Epub 2016 Jan 18.


The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.

Kozarcanin H, Lood C, Munthe-Fog L, Sandholm K, Hamad OA, Bengtsson AA, Skjoedt MO, Huber-Lang M, Garred P, Ekdahl KN, Nilsson B.

J Thromb Haemost. 2016 Mar;14(3):531-45. doi: 10.1111/jth.13208. Epub 2016 Feb 15.


Type I interferon-mediated skewing of the serotonin synthesis is associated with severe disease in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Klint C, Wenglén C, Nielsen CT, Heegaard NH, Jönsen A, Kahn R, Bengtsson AA.

PLoS One. 2015 Apr 21;10(4):e0125109. doi: 10.1371/journal.pone.0125109. eCollection 2015.


Plasma levels of galectin-3-binding protein reflect type I interferon activity and are increased in patients with systemic lupus erythematosus.

Nielsen CT, Lood C, Ostergaard O, Iversen LV, Voss A, Bengtsson A, Jacobsen S, Heegaard NH.

Lupus Sci Med. 2014 Nov 19;1(1):e000026. doi: 10.1136/lupus-2014-000026. eCollection 2014.


Temperature effects on haemostasis in whole blood from ticagrelor- and aspirin-treated patients with acute coronary syndrome.

Kander T, Brokopp J, Erlinge D, Lood C, Schött U.

Scand J Clin Lab Invest. 2015 Jan;75(1):27-35. doi: 10.3109/00365513.2014.965735. Epub 2014 Nov 3.


Beyond apoptosis in lupus.

Colonna L, Lood C, Elkon KB.

Curr Opin Rheumatol. 2014 Sep;26(5):459-66. doi: 10.1097/BOR.0000000000000083. Review.


Platelet activation and anti-phospholipid antibodies collaborate in the activation of the complement system on platelets in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Sturfelt G, Jönsen A, Truedsson L, Bengtsson AA.

PLoS One. 2014 Jun 12;9(6):e99386. doi: 10.1371/journal.pone.0099386. eCollection 2014.


Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization.

Ohlsson SM, Linge CP, Gullstrand B, Lood C, Johansson A, Ohlsson S, Lundqvist A, Bengtsson AA, Carlsson F, Hellmark T.

Clin Immunol. 2014 May-Jun;152(1-2):10-9. doi: 10.1016/j.clim.2014.02.016. Epub 2014 Mar 12.


Pharmacological importance of optically active tetrahydro-β-carbolines and synthetic approaches to create the C1 stereocenter.

Laine AE, Lood C, Koskinen AM.

Molecules. 2014 Jan 27;19(2):1544-67. doi: 10.3390/molecules19021544. Review.


Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus.

Tydén H, Lood C, Gullstrand B, Jönsen A, Nived O, Sturfelt G, Truedsson L, Ivars F, Leanderson T, Bengtsson AA.

Rheumatology (Oxford). 2013 Nov;52(11):2048-55. doi: 10.1093/rheumatology/ket263. Epub 2013 Aug 13.


Circulating microRNA expression profiles associated with systemic lupus erythematosus.

Carlsen AL, Schetter AJ, Nielsen CT, Lood C, Knudsen S, Voss A, Harris CC, Hellmark T, Segelmark M, Jacobsen S, Bengtsson AA, Heegaard NH.

Arthritis Rheum. 2013 May;65(5):1324-34. doi: 10.1002/art.37890.


Increased serum type I interferon activity in early systemic sclerosis patients is associated with antibodies against Sjögren's syndrome antigens and nuclear ribonucleoprotein antigens.

Wuttge DM, Lood C, Tufvesson E, Scheja A, Truedsson L, Bengtsson AA, Hesselstrand R.

Scand J Rheumatol. 2013;42(3):235-40. doi: 10.3109/03009742.2012.736532. Epub 2013 Feb 5.


Increased C1q, C4 and C3 deposition on platelets in patients with systemic lupus erythematosus--a possible link to venous thrombosis?

Lood C, Eriksson S, Gullstrand B, Jönsen A, Sturfelt G, Truedsson L, Bengtsson AA.

Lupus. 2012 Nov;21(13):1423-32. doi: 10.1177/0961203312457210. Epub 2012 Aug 9.


Vaccination against encapsulated bacteria in hereditary C2 deficiency results in antibody response and opsonization due to antibody-dependent complement activation.

Jönsson G, Lood C, Gullstrand B, Holmström E, Selander B, Braconier JH, Sturfelt G, Bengtsson AA, Truedsson L.

Clin Immunol. 2012 Sep;144(3):214-27. doi: 10.1016/j.clim.2012.06.008. Epub 2012 Jul 6.


Combination of autoantibodies against different histone proteins influences complement-dependent phagocytosis of necrotic cell material by polymorphonuclear leukocytes in systemic lupus erythematosus.

Gullstrand B, Lefort MH, Tydén H, Jönsen A, Lood C, Johansson A, Jacobsen S, Truedsson L, Bengtsson AA.

J Rheumatol. 2012 Aug;39(8):1619-27. doi: 10.3899/jrheum.111511. Epub 2012 Jul 1.


IgG glycan hydrolysis by endoglycosidase S diminishes the proinflammatory properties of immune complexes from patients with systemic lupus erythematosus: a possible new treatment?

Lood C, Allhorn M, Lood R, Gullstrand B, Olin AI, Rönnblom L, Truedsson L, Collin M, Bengtsson AA.

Arthritis Rheum. 2012 Aug;64(8):2698-706. doi: 10.1002/art.34454.


Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease.

Leffler J, Martin M, Gullstrand B, Tydén H, Lood C, Truedsson L, Bengtsson AA, Blom AM.

J Immunol. 2012 Apr 1;188(7):3522-31. doi: 10.4049/jimmunol.1102404. Epub 2012 Feb 17.


Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus.

Lood C, Stenström M, Tydén H, Gullstrand B, Källberg E, Leanderson T, Truedsson L, Sturfelt G, Ivars F, Bengtsson AA.

Arthritis Res Ther. 2011 Apr 14;13(2):R60. doi: 10.1186/ar3314.


Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.

Martini PG, Cook LC, Alderucci S, Norton AW, Lundberg DM, Fish SM, Langsetmo K, Jönsson G, Lood C, Gullstrand B, Zaleski KJ, Savioli N, Lottherand J, Bedard C, Gill J, Concino MF, Heartlein MW, Truedsson L, Powell JL, Tzianabos AO.

BMC Immunol. 2010 Aug 20;11:43. doi: 10.1186/1471-2172-11-43.


Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease.

Lood C, Amisten S, Gullstrand B, Jönsen A, Allhorn M, Truedsson L, Sturfelt G, Erlinge D, Bengtsson AA.

Blood. 2010 Sep 16;116(11):1951-7. doi: 10.1182/blood-2010-03-274605. Epub 2010 Jun 10.


The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis.

Allhorn M, Briceño JG, Baudino L, Lood C, Olsson ML, Izui S, Collin M.

Blood. 2010 Jun 17;115(24):5080-8. doi: 10.1182/blood-2009-08-239020. Epub 2010 Mar 31.


C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis.

Lood C, Gullstrand B, Truedsson L, Olin AI, Alm GV, Rönnblom L, Sturfelt G, Eloranta ML, Bengtsson AA.

Arthritis Rheum. 2009 Oct;60(10):3081-90. doi: 10.1002/art.24852.

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