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Items: 1 to 50 of 268

1.

34th ASMS Asilomar Conference on Quantitative Analysis of Posttranslational Modifications by Mass Spectrometry.

Loo JA.

J Am Soc Mass Spectrom. 2019 Nov 11. doi: 10.1007/s13361-019-02351-y. [Epub ahead of print] No abstract available.

PMID:
31713173
2.

N-terminal autoprocessing and acetylation of multifunctional-autoprocessing repeats-in-toxins (MARTX) Makes Caterpillars Floppy-like effector is stimulated by adenosine diphosphate (ADP)-Ribosylation Factor 1 in advance of Golgi fragmentation.

Herrera A, Muroski J, Sengupta R, Nguyen HH, Agarwal S, Ogorzalek Loo RR, Mattoo S, Loo JA, Satchell KJF.

Cell Microbiol. 2019 Oct 28:e13133. doi: 10.1111/cmi.13133. [Epub ahead of print]

PMID:
31658406
3.

A five-level classification system for proteoform identifications.

Smith LM, Thomas PM, Shortreed MR, Schaffer LV, Fellers RT, LeDuc RD, Tucholski T, Ge Y, Agar JN, Anderson LC, Chamot-Rooke J, Gault J, Loo JA, Paša-Tolić L, Robinson CV, Schlüter H, Tsybin YO, Vilaseca M, Vizcaíno JA, Danis PO, Kelleher NL.

Nat Methods. 2019 Oct;16(10):939-940. doi: 10.1038/s41592-019-0573-x. No abstract available.

PMID:
31451767
4.

Time-Dependent Measurement of Nrf2-Regulated Antioxidant Response to Ionizing Radiation Toward Identifying Potential Protein Biomarkers for Acute Radiation Injury.

Liu K, Singer E, Cohn W, Micewicz ED, McBride WH, Whitelegge JP, Loo JA.

Proteomics Clin Appl. 2019 Nov;13(6):e1900035. doi: 10.1002/prca.201900035. Epub 2019 Sep 4.

PMID:
31419066
5.

Mass Spectrometry-Based Tissue Imaging of Small Molecules.

Ferguson CN, Fowler JWM, Waxer JF, Gatti RA, Loo JA.

Adv Exp Med Biol. 2019;1140:99-109. doi: 10.1007/978-3-030-15950-4_5. Review.

PMID:
31347043
6.

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry.

Donnelly DP, Rawlins CM, DeHart CJ, Fornelli L, Schachner LF, Lin Z, Lippens JL, Aluri KC, Sarin R, Chen B, Lantz C, Jung W, Johnson KR, Koller A, Wolff JJ, Campuzano IDG, Auclair JR, Ivanov AR, Whitelegge JP, Paša-Tolić L, Chamot-Rooke J, Danis PO, Smith LM, Tsybin YO, Loo JA, Ge Y, Kelleher NL, Agar JN.

Nat Methods. 2019 Jul;16(7):587-594. doi: 10.1038/s41592-019-0457-0. Epub 2019 Jun 27. Review.

7.

The l-isoaspartate modification within protein fragments in the aging lens can promote protein aggregation.

Warmack RA, Shawa H, Liu K, Lopez K, Loo JA, Horwitz J, Clarke SG.

J Biol Chem. 2019 Aug 9;294(32):12203-12219. doi: 10.1074/jbc.RA119.009052. Epub 2019 Jun 25.

PMID:
31239355
8.

Native and Denaturing MS Protein Deconvolution for Biopharma: Monoclonal Antibodies and Antibody-Drug Conjugates to Polydisperse Membrane Proteins and Beyond.

Campuzano IDG, Robinson JH, Hui JO, Shi SD, Netirojjanakul C, Nshanian M, Egea PF, Lippens JL, Bagal D, Loo JA, Bern M.

Anal Chem. 2019 Aug 6;91(15):9472-9480. doi: 10.1021/acs.analchem.9b00062. Epub 2019 Jul 12.

PMID:
31194911
9.

Top-Down Protein Identification using a Time-of-Flight Mass Spectrometer and Data Independent Acquisition.

Lakshmanan R, Loo JA.

Int J Mass Spectrom. 2019 Jan;435:136-144. doi: 10.1016/j.ijms.2018.10.023. Epub 2018 Oct 22.

PMID:
31105465
10.

Top or Middle? Up or Down? Toward a Standard Lexicon for Protein Top-Down and Allied Mass Spectrometry Approaches.

Lermyte F, Tsybin YO, O'Connor PB, Loo JA.

J Am Soc Mass Spectrom. 2019 Jul;30(7):1149-1157. doi: 10.1007/s13361-019-02201-x. Epub 2019 May 9.

11.

Syntrophus aciditrophicus uses the same enzymes in a reversible manner to degrade and synthesize aromatic and alicyclic acids.

James KL, Kung JW, Crable BR, Mouttaki H, Sieber JR, Nguyen HH, Yang Y, Xie Y, Erde J, Wofford NQ, Karr EA, Loo JA, Ogorzalek Loo RR, Gunsalus RP, McInerney MJ.

Environ Microbiol. 2019 May;21(5):1833-1846. doi: 10.1111/1462-2920.14601.

PMID:
30895699
12.

Proteomics identification of radiation-induced changes of membrane proteins in the rat model of arteriovenous malformation in pursuit of targets for brain AVM molecular therapy.

Simonian M, Shirasaki D, Lee VS, Bervini D, Grace M, Loo RRO, Loo JA, Molloy MP, Stoodley MA.

Clin Proteomics. 2018 Dec 26;15:43. doi: 10.1186/s12014-018-9217-x. eCollection 2018.

13.

The molecular tweezer CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro and in the G93A-SOD1 mouse model of ALS.

Malik R, Meng H, Wongkongkathep P, Corrales CI, Sepanj N, Atlasi RS, Klärner FG, Schrader T, Spencer MJ, Loo JA, Wiedau M, Bitan G.

J Biol Chem. 2019 Mar 8;294(10):3501-3513. doi: 10.1074/jbc.RA118.005940. Epub 2019 Jan 2.

PMID:
30602569
14.

Rapid LC-MS Method for Accurate Molecular Weight Determination of Membrane and Hydrophobic Proteins.

Lippens JL, Egea PF, Spahr C, Vaish A, Keener JE, Marty MT, Loo JA, Campuzano IDG.

Anal Chem. 2018 Nov 20;90(22):13616-13623. doi: 10.1021/acs.analchem.8b03843. Epub 2018 Oct 31.

15.

Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator.

Nshanian M, Lantz C, Wongkongkathep P, Schrader T, Klärner FG, Blümke A, Despres C, Ehrmann M, Smet-Nocca C, Bitan G, Loo JA.

J Am Soc Mass Spectrom. 2019 Jan;30(1):16-23. doi: 10.1007/s13361-018-2027-6. Epub 2018 Jul 30. Erratum in: J Am Soc Mass Spectrom. 2019 Mar;30(3):561.

PMID:
30062477
16.

Focus on Application of Photons and Radicals for Mass Spectrometry, Honoring Dr. Ryan Julian, Recipient of the 2017 ASMS Biemann Medal.

Loo JA.

J Am Soc Mass Spectrom. 2018 Sep;29(9):1757-1759. doi: 10.1007/s13361-018-2017-8. No abstract available.

PMID:
30062474
17.

Extracting Charge and Mass Information from Highly Congested Mass Spectra Using Fourier-Domain Harmonics.

Cleary SP, Li H, Bagal D, Loo JA, Campuzano IDG, Prell JS.

J Am Soc Mass Spectrom. 2018 Oct;29(10):2067-2080. doi: 10.1007/s13361-018-2018-7. Epub 2018 Jul 12.

18.

Native Top-Down Mass Spectrometry and Ion Mobility MS for Characterizing the Cobalt and Manganese Metal Binding of α-Synuclein Protein.

Wongkongkathep P, Han JY, Choi TS, Yin S, Kim HI, Loo JA.

J Am Soc Mass Spectrom. 2018 Sep;29(9):1870-1880. doi: 10.1007/s13361-018-2002-2. Epub 2018 Jun 27.

19.

Protein Labeling via a Specific Lysine-Isopeptide Bond Using the Pilin Polymerizing Sortase from Corynebacterium diphtheriae.

McConnell SA, Amer BR, Muroski J, Fu J, Chang C, Ogorzalek Loo RR, Loo JA, Osipiuk J, Ton-That H, Clubb RT.

J Am Chem Soc. 2018 Jul 11;140(27):8420-8423. doi: 10.1021/jacs.8b05200. Epub 2018 Jun 28.

20.

In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking.

Chang C, Amer BR, Osipiuk J, McConnell SA, Huang IH, Hsieh V, Fu J, Nguyen HH, Muroski J, Flores E, Ogorzalek Loo RR, Loo JA, Putkey JA, Joachimiak A, Das A, Clubb RT, Ton-That H.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5477-E5486. doi: 10.1073/pnas.1800954115. Epub 2018 May 29.

21.

Enhancing Sensitivity of Liquid Chromatography-Mass Spectrometry of Peptides and Proteins Using Supercharging Agents.

Nshanian M, Lakshmanan R, Chen H, Ogorzalek Loo RR, Loo JA.

Int J Mass Spectrom. 2018 Apr;427:157-164. doi: 10.1016/j.ijms.2017.12.006. Epub 2017 Dec 24.

22.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

23.

Radical solutions: Principles and application of electron-based dissociation in mass spectrometry-based analysis of protein structure.

Lermyte F, Valkenborg D, Loo JA, Sobott F.

Mass Spectrom Rev. 2018 Nov;37(6):750-771. doi: 10.1002/mas.21560. Epub 2018 Feb 9. Review.

24.

ProForma: A Standard Proteoform Notation.

LeDuc RD, Schwämmle V, Shortreed MR, Cesnik AJ, Solntsev SK, Shaw JB, Martin MJ, Vizcaino JA, Alpi E, Danis P, Kelleher NL, Smith LM, Ge Y, Agar JN, Chamot-Rooke J, Loo JA, Pasa-Tolic L, Tsybin YO.

J Proteome Res. 2018 Mar 2;17(3):1321-1325. doi: 10.1021/acs.jproteome.7b00851. Epub 2018 Feb 14.

25.

Supramolecular Modulation of Structural Polymorphism in Pathogenic α-Synuclein Fibrils Using Copper(II) Coordination.

Choi TS, Lee J, Han JY, Jung BC, Wongkongkathep P, Loo JA, Lee MJ, Kim HI.

Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3099-3103. doi: 10.1002/anie.201712286. Epub 2018 Feb 16.

PMID:
29368447
26.

Fixed-Charge Trimethyl Pyrilium Modification for Enabling Enhanced Top-Down Mass Spectrometry Sequencing of Intact Protein Complexes.

Polasky DA, Lermyte F, Nshanian M, Sobott F, Andrews PC, Loo JA, Ruotolo BT.

Anal Chem. 2018 Feb 20;90(4):2756-2764. doi: 10.1021/acs.analchem.7b04806. Epub 2018 Feb 2.

27.

An integrated native mass spectrometry and top-down proteomics method that connects sequence to structure and function of macromolecular complexes.

Li H, Nguyen HH, Ogorzalek Loo RR, Campuzano IDG, Loo JA.

Nat Chem. 2018 Feb;10(2):139-148. doi: 10.1038/nchem.2908. Epub 2018 Jan 1.

28.

To Improve is to Change.

Loo JA.

J Am Soc Mass Spectrom. 2018 Jan;29(1):1-3. doi: 10.1007/s13361-017-1848-z. No abstract available.

PMID:
29256015
29.

Native-MS Analysis of Monoclonal Antibody Conjugates by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.

Campuzano IDG, Netirojjanakul C, Nshanian M, Lippens JL, Kilgour DPA, Van Orden S, Loo JA.

Anal Chem. 2018 Jan 2;90(1):745-751. doi: 10.1021/acs.analchem.7b03021. Epub 2017 Dec 18.

PMID:
29193956
30.

Submicrometer Emitter ESI Tips for Native Mass Spectrometry of Membrane Proteins in Ionic and Nonionic Detergents.

Susa AC, Lippens JL, Xia Z, Loo JA, Campuzano IDG, Williams ER.

J Am Soc Mass Spectrom. 2018 Jan;29(1):203-206. doi: 10.1007/s13361-017-1793-x. Epub 2017 Oct 12.

31.

Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry as a Platform for Characterizing Multimeric Membrane Protein Complexes.

Lippens JL, Nshanian M, Spahr C, Egea PF, Loo JA, Campuzano IDG.

J Am Soc Mass Spectrom. 2018 Jan;29(1):183-193. doi: 10.1007/s13361-017-1799-4. Epub 2017 Oct 2.

32.

New astroglial injury-defined biomarkers for neurotrauma assessment.

Halford J, Shen S, Itamura K, Levine J, Chong AC, Czerwieniec G, Glenn TC, Hovda DA, Vespa P, Bullock R, Dietrich WD, Mondello S, Loo JA, Wanner IB.

J Cereb Blood Flow Metab. 2017 Oct;37(10):3278-3299. doi: 10.1177/0271678X17724681. Epub 2017 Aug 17.

33.

Structural Characterization of a Thrombin-Aptamer Complex by High Resolution Native Top-Down Mass Spectrometry.

Zhang J, Loo RRO, Loo JA.

J Am Soc Mass Spectrom. 2017 Sep;28(9):1815-1822. doi: 10.1007/s13361-017-1751-7. Epub 2017 Jul 28.

34.

Top-down/Bottom-up Mass Spectrometry Workflow Using Dissolvable Polyacrylamide Gels.

Takemori N, Takemori A, Wongkongkathep P, Nshanian M, Loo RRO, Lermyte F, Loo JA.

Anal Chem. 2017 Aug 15;89(16):8244-8250. doi: 10.1021/acs.analchem.7b00357. Epub 2017 Aug 2.

35.

Identification of protein targets in cerebral endothelial cells for brain arteriovenous malformation (AVMs) molecular therapies.

Simonian M, Loo RRO, Rannulu N, Loo JA, Molloy MP, Stoodley MA.

Clin Proteomics. 2017 May 16;14:17. doi: 10.1186/s12014-017-9151-3. eCollection 2017.

36.

Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01.

Vöpel T, Bravo-Rodriguez K, Mittal S, Vachharajani S, Gnutt D, Sharma A, Steinhof A, Fatoba O, Ellrichmann G, Nshanian M, Heid C, Loo JA, Klärner FG, Schrader T, Bitan G, Wanker EE, Ebbinghaus S, Sanchez-Garcia E.

J Am Chem Soc. 2017 Apr 26;139(16):5640-5643. doi: 10.1021/jacs.6b11039. Epub 2017 Apr 13.

37.

Keystone predation and molecules of keystone significance.

Zimmer RK, Ferrier GA, Kim SJ, Ogorzalek Loo RR, Zimmer CA, Loo JA.

Ecology. 2017 Jun;98(6):1710-1721. doi: 10.1002/ecy.1849. Epub 2017 May 15.

38.

Editorial and Review: 28th ASMS Sanibel Conference on Mass Spectrometry-Characterization of Protein Therapeutics by Mass Spectrometry.

Sperry JB, Chen G, Loo JA.

J Am Soc Mass Spectrom. 2017 May;28(5):781-785. doi: 10.1007/s13361-017-1629-8. No abstract available.

PMID:
28374311
39.

Native MS Analysis of Bacteriorhodopsin and an Empty Nanodisc by Orthogonal Acceleration Time-of-Flight, Orbitrap and Ion Cyclotron Resonance.

Campuzano ID, Li H, Bagal D, Lippens JL, Svitel J, Kurzeja RJ, Xu H, Schnier PD, Loo JA.

Anal Chem. 2016 Dec 20;88(24):12427-12436. doi: 10.1021/acs.analchem.6b03762. Epub 2016 Dec 1.

40.

Structural Characterization of Native Proteins and Protein Complexes by Electron Ionization Dissociation-Mass Spectrometry.

Li H, Sheng Y, McGee W, Cammarata M, Holden D, Loo JA.

Anal Chem. 2017 Mar 7;89(5):2731-2738. doi: 10.1021/acs.analchem.6b02377. Epub 2017 Feb 22.

41.

Improving Proteome Coverage and Sample Recovery with Enhanced FASP (eFASP) for Quantitative Proteomic Experiments.

Erde J, Loo RR, Loo JA.

Methods Mol Biol. 2017;1550:11-18. doi: 10.1007/978-1-4939-6747-6_2.

42.

Editorial and Review: 31st ASMS Asilomar Conference on Native Mass Spectrometry-Based Structural Biology.

Loo JA, Heck AJ.

J Am Soc Mass Spectrom. 2017 Jan;28(1):1-4. doi: 10.1007/s13361-016-1540-8. No abstract available.

PMID:
27896696
43.

A multifunctional chemical cue drives opposing demographic processes and structures ecological communities.

Zimmer RK, Ferrier GA, Kim SJ, Kaddis CS, Zimmer CA, Loo JA.

Ecology. 2016 Sep;97(9):2232-2239. doi: 10.1002/ecy.1455.

44.

S2'-subsite variations between human and mouse enzymes (plasmin, factor XIa, kallikrein) elucidate inhibition differences by tissue factor pathway inhibitor -2 domain1-wild-type, Leu17Arg-mutant and aprotinin.

Vadivel K, Kumar Y, Ogueli GI, Ponnuraj SM, Wongkongkathep P, Loo JA, Bajaj MS, Bajaj SP.

J Thromb Haemost. 2016 Dec;14(12):2509-2523. doi: 10.1111/jth.13538. Epub 2016 Nov 19.

45.

Focus on Bioinformatics, Software, and MS-Based "Omics," Honoring Dr. Michael J. MacCoss, Recipient of the 2015 ASMS Biemann Medal.

Loo JA, Matthews DE, Yates JR 3rd.

J Am Soc Mass Spectrom. 2016 Nov;27(11):1715-1718. No abstract available.

PMID:
27696304
46.

Pyrophosphate-Dependent ATP Formation from Acetyl Coenzyme A in Syntrophus aciditrophicus, a New Twist on ATP Formation.

James KL, Ríos-Hernández LA, Wofford NQ, Mouttaki H, Sieber JR, Sheik CS, Nguyen HH, Yang Y, Xie Y, Erde J, Rohlin L, Karr EA, Loo JA, Ogorzalek Loo RR, Hurst GB, Gunsalus RP, Szweda LI, McInerney MJ.

MBio. 2016 Aug 16;7(4). pii: e01208-16. doi: 10.1128/mBio.01208-16.

47.

MULTIFUNCin: A Multifunctional Protein Cue Induces Habitat Selection by, and Predation on, Barnacles.

Ferrier GA, Kim SJ, Kaddis CS, Loo JA, Ann Zimmer C, Zimmer RK.

Integr Comp Biol. 2016 Nov;56(5):901-913. Epub 2016 Jul 1.

48.
49.
50.

Salt Bridge Rearrangement (SaBRe) Explains the Dissociation Behavior of Noncovalent Complexes.

Loo RR, Loo JA.

J Am Soc Mass Spectrom. 2016 Jun;27(6):975-90. doi: 10.1007/s13361-016-1375-3. Epub 2016 Apr 6.

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