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FLT-PET-CT for the Detection of Disease Recurrence After Stereotactic Ablative Radiotherapy or Hyperfractionation for Thoracic Malignancy: A Prospective Pilot Study.

Hiniker SM, Sodji Q, Quon A, Gutkin PM, Arksey N, Graves EE, Chin FT, Maxim PG, Diehn M, Loo BW Jr.

Front Oncol. 2019 May 31;9:467. doi: 10.3389/fonc.2019.00467. eCollection 2019.


PHASER: A platform for clinical translation of FLASH cancer radiotherapy.

Maxim PG, Tantawi SG, Loo BW Jr.

Radiother Oncol. 2019 Jun 6. pii: S0167-8140(19)30404-9. doi: 10.1016/j.radonc.2019.05.005. [Epub ahead of print]


Conical beam geometry intensity-modulated radiation therapy.

Schüler E, Wang L, Loo BW, Maxim PG.

Phys Med Biol. 2019 Jun 20;64(12):125014. doi: 10.1088/1361-6560/ab246f.


Increases in Serial Pretreatment 18F-FDG PET-CT Metrics Predict Survival in Early Stage Non-Small Cell Lung Cancer Treated With Stereotactic Ablative Radiation Therapy.

Prionas ND, von Eyben R, Yi E, Aggarwal S, Shaffer J, Bazan J, Eastham D, Maxim PG, Graves EE, Diehn M, Gensheimer MF, Loo BW Jr.

Adv Radiat Oncol. 2018 Nov 26;4(2):429-437. doi: 10.1016/j.adro.2018.11.006. eCollection 2019 Apr-Jun.


Lessons Learned From Hurricane Maria in Puerto Rico: Practical Measures to Mitigate the Impact of a Catastrophic Natural Disaster on Radiation Oncology Patients.

Gay HA, Santiago R, Gil B, Remedios C, Montes PJ, López-Araujo J, Chévere CM, Imbert WS, White J, Arthur DW, Horton JK, Jagsi R, Rabinovich R, Beriwal S, Viswanathan A, Erickson BA, Rengan R, Palma D, Loo BW Jr, Kavanaugh JA, Bradley J, Yom SS, Harari PM, Lee Burnett O 3rd.

Pract Radiat Oncol. 2019 Apr 15. pii: S1879-8500(19)30079-7. doi: 10.1016/j.prro.2019.03.007. [Epub ahead of print]


Mortality of lung cancer as a second primary malignancy: A population-based cohort study.

Deng L, Harðardottír H, Song H, Xiao Z, Jiang C, Wang Q, Valdimarsdóttir U, Cheng H, Loo BW, Lu D.

Cancer Med. 2019 Jun;8(6):3269-3277. doi: 10.1002/cam4.2172. Epub 2019 Apr 16.


SABR-COMET: harbinger of a new cancer treatment paradigm.

Loo BW Jr, Diehn M.

Lancet. 2019 May 18;393(10185):2013-2014. doi: 10.1016/S0140-6736(19)30278-8. Epub 2019 Apr 11. No abstract available.


Local Control After Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer.

Lee P, Loo BW Jr, Biswas T, Ding GX, El Naqa IM, Jackson A, Kong FM, LaCouture T, Miften M, Solberg T, Tome WA, Tai A, Yorke E, Li XA.

Int J Radiat Oncol Biol Phys. 2019 Apr 5. pii: S0360-3016(19)30572-3. doi: 10.1016/j.ijrobp.2019.03.045. [Epub ahead of print]


The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy.

Starkov P, Aguilera TA, Golden DI, Shultz DB, Trakul N, Maxim PG, Le QT, Loo BW, Diehn M, Depeursinge A, Rubin DL.

Br J Radiol. 2019 Feb;92(1094):20180228. doi: 10.1259/bjr.20180228. Epub 2018 Nov 20.


NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018.

Kalemkerian GP, Loo BW, Akerley W, Attia A, Bassetti M, Boumber Y, Decker R, Dobelbower MC, Dowlati A, Downey RJ, Florsheim C, Ganti AKP, Grecula JC, Gubens MA, Hann CL, Hayman JA, Heist RS, Koczywas M, Merritt RE, Mohindra N, Molina J, Moran CA, Morgensztern D, Pokharel S, Portnoy DC, Rhodes D, Rusthoven C, Santana-Davila R, Williams CC, Hoffmann KG, Hughes M.

J Natl Compr Canc Netw. 2018 Oct;16(10):1171-1182. doi: 10.6004/jnccn.2018.0079.


Invasive nodal evaluation prior to stereotactic ablative radiation for non-small cell lung cancer.

Harris JP, Nwachukwu C, Qian Y, Pollom E, Loo BW, Das M, Diehn M.

Lung Cancer. 2018 Oct;124:76-85. doi: 10.1016/j.lungcan.2018.07.033. Epub 2018 Jul 23.


NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 5.2018.

Ettinger DS, Aisner DL, Wood DE, Akerley W, Bauman J, Chang JY, Chirieac LR, D'Amico TA, Dilling TJ, Dobelbower M, Govindan R, Gubens MA, Hennon M, Horn L, Lackner RP, Lanuti M, Leal TA, Lilenbaum R, Lin J, Loo BW, Martins R, Otterson GA, Patel SP, Reckamp K, Riely GJ, Schild SE, Shapiro TA, Stevenson J, Swanson SJ, Tauer K, Yang SC, Gregory K, Hughes M.

J Natl Compr Canc Netw. 2018 Jul;16(7):807-821. doi: 10.6004/jnccn.2018.0062.


18F-EF5 PET-based Imageable Hypoxia Predicts Local Recurrence in Tumors Treated With Highly Conformal Radiation Therapy.

Qian Y, Von Eyben R, Liu Y, Chin FT, Miao Z, Apte S, Carter JN, Binkley MS, Pollom EL, Harris JP, Prionas ND, Kissel M, Simmons A, Diehn M, Shultz DB, Brown JM, Maxim PG, Koong AC, Graves EE, Loo BW Jr.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1183-1192. doi: 10.1016/j.ijrobp.2018.03.045. Epub 2018 Apr 18.


Stereotactic Body Radiation Therapy for Operable Early-Stage Lung Cancer: Findings From the NRG Oncology RTOG 0618 Trial.

Timmerman RD, Paulus R, Pass HI, Gore EM, Edelman MJ, Galvin J, Straube WL, Nedzi LA, McGarry RC, Robinson CG, Schiff PB, Chang G, Loo BW Jr, Bradley JD, Choy H.

JAMA Oncol. 2018 Sep 1;4(9):1263-1266. doi: 10.1001/jamaoncol.2018.1251.


Prognostic Value of Pretreatment FDG-PET Parameters in High-dose Image-guided Radiotherapy for Oligometastatic Non-Small-cell Lung Cancer.

Chin AL, Kumar KA, Guo HH, Maxim PG, Wakelee H, Neal JW, Diehn M, Loo BW Jr, Gensheimer MF.

Clin Lung Cancer. 2018 Sep;19(5):e581-e588. doi: 10.1016/j.cllc.2018.04.003. Epub 2018 Apr 19.


A Feasibility Study of Single-inhalation, Single-energy Xenon-enhanced CT for High-resolution Imaging of Regional Lung Ventilation in Humans.

Pinkham DW, Negahdar M, Yamamoto T, Mittra E, Diehn M, Nair VS, Keall PJ, Maxim PG, Loo BW Jr.

Acad Radiol. 2019 Jan;26(1):38-49. doi: 10.1016/j.acra.2018.03.006. Epub 2018 Mar 29.


Chest wall dose reduction using noncoplanar volumetric modulated arc radiation therapy for lung stereotactic ablative radiation therapy.

Yu AS, Maxim PG, Loo BW Jr, Gensheimer MF.

Pract Radiat Oncol. 2018 Jul - Aug;8(4):e199-e207. doi: 10.1016/j.prro.2017.12.005. Epub 2017 Dec 19.


A Quantitative CT Imaging Signature Predicts Survival and Complements Established Prognosticators in Stage I Non-Small Cell Lung Cancer.

Lee J, Li B, Cui Y, Sun X, Wu J, Zhu H, Yu J, Gensheimer MF, Loo BW Jr, Diehn M, Li R.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1098-1106. doi: 10.1016/j.ijrobp.2018.01.006. Epub 2018 Jan 10.


Line-Enhanced Deformable Registration of Pulmonary Computed Tomography Images Before and After Radiation Therapy With Radiation-Induced Fibrosis.

King M, Sensakovic WF, Maxim P, Diehn M, Loo BW, Xing L.

Technol Cancer Res Treat. 2018 Jan 1;17:1533034617749419. doi: 10.1177/1533034617749419.


Optimal imaging surveillance after stereotactic ablative radiation therapy for early-stage non-small cell lung cancer: Findings of an International Delphi Consensus Study.

Nguyen TK, Senan S, Bradley JD, Franks K, Giuliani M, Guckenberger M, Landis M, Loo BW Jr, Louie AV, Onishi H, Schmidt H, Timmerman R, Videtic GMM, Palma DA.

Pract Radiat Oncol. 2018 Mar - Apr;8(2):e71-e78. doi: 10.1016/j.prro.2017.10.008. Epub 2017 Dec 30.


Thermal limits on MV x-ray production by bremsstrahlung targets in the context of novel linear accelerators.

Wang J, Trovati S, Borchard PM, Loo BW Jr, Maxim PG, Fahrig R.

Med Phys. 2017 Dec;44(12):6610-6620. doi: 10.1002/mp.12615. Epub 2017 Nov 6.


Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling.

Chaudhuri AA, Chabon JJ, Lovejoy AF, Newman AM, Stehr H, Azad TD, Khodadoust MS, Esfahani MS, Liu CL, Zhou L, Scherer F, Kurtz DM, Say C, Carter JN, Merriott DJ, Dudley JC, Binkley MS, Modlin L, Padda SK, Gensheimer MF, West RB, Shrager JB, Neal JW, Wakelee HA, Loo BW Jr, Alizadeh AA, Diehn M.

Cancer Discov. 2017 Dec;7(12):1394-1403. doi: 10.1158/2159-8290.CD-17-0716. Epub 2017 Sep 24.


Mid-radiotherapy PET/CT for prognostication and detection of early progression in patients with stage III non-small cell lung cancer.

Gensheimer MF, Hong JC, Chang-Halpenny C, Zhu H, Eclov NCW, To J, Murphy JD, Wakelee HA, Neal JW, Le QT, Hara WY, Quon A, Maxim PG, Graves EE, Olson MR, Diehn M, Loo BW Jr.

Radiother Oncol. 2017 Nov;125(2):338-343. doi: 10.1016/j.radonc.2017.08.007. Epub 2017 Aug 19.


Prognostic value and molecular correlates of a CT image-based quantitative pleural contact index in early stage NSCLC.

Lee J, Cui Y, Sun X, Li B, Wu J, Li D, Gensheimer MF, Loo BW Jr, Diehn M, Li R.

Eur Radiol. 2018 Feb;28(2):736-746. doi: 10.1007/s00330-017-4996-4. Epub 2017 Aug 7.


Sinoatrial node toxicity after stereotactic ablative radiation therapy to lung tumors.

Qian Y, Zhu H, Pollom EL, Durkee BY, Chaudhuri AA, Gensheimer MF, Diehn M, Shultz DB, Loo BW Jr.

Pract Radiat Oncol. 2017 Nov - Dec;7(6):e525-e529. doi: 10.1016/j.prro.2017.04.005. Epub 2017 Apr 13.


Practical workflow for rapid prototyping of radiation therapy positioning devices.

Gensheimer MF, Bush K, Juang T, Herzberg B, Villegas M, Maxim PG, Diehn M, Loo BW Jr.

Pract Radiat Oncol. 2017 Nov - Dec;7(6):442-445. doi: 10.1016/j.prro.2017.05.004. Epub 2017 May 13. No abstract available.


Randomized Phase II Study of Preoperative Chemoradiotherapy ± Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer: NRG Oncology RTOG 0839.

Edelman MJ, Hu C, Le QT, Donington JS, D'Souza WD, Dicker AP, Loo BW, Gore EM, Videtic GMM, Evans NR, Leach JW, Diehn M, Feigenberg SJ, Chen Y, Paulus R, Bradley JD.

J Thorac Oncol. 2017 Sep;12(9):1413-1420. doi: 10.1016/j.jtho.2017.06.007. Epub 2017 Jun 16.


A population-based comparative effectiveness study of chemoradiation regimens and sequences in stage III non-small cell lung cancer.

Harris JP, Patel MI, Loo BW, Wakelee HA, Diehn M.

Lung Cancer. 2017 Jun;108:173-182. doi: 10.1016/j.lungcan.2017.03.017. Epub 2017 Mar 29.


Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer.

Shah JL, Loo BW Jr.

Semin Radiat Oncol. 2017 Jul;27(3):218-228. doi: 10.1016/j.semradonc.2017.03.001. Epub 2017 Mar 16. Review.


Normal Tissue Constraints for Abdominal and Thoracic Stereotactic Body Radiotherapy.

Pollom EL, Chin AL, Diehn M, Loo BW, Chang DT.

Semin Radiat Oncol. 2017 Jul;27(3):197-208. doi: 10.1016/j.semradonc.2017.02.001. Epub 2017 Feb 20. Review.


Pulmonary function after lung tumor stereotactic ablative radiotherapy depends on regional ventilation within irradiated lung.

Binkley MS, King MT, Shrager JB, Bush K, Chaudhuri AA, Popat R, Gensheimer MF, Maxim PG, Henry Guo H, Diehn M, Nair VS, Loo BW Jr.

Radiother Oncol. 2017 May;123(2):270-275. doi: 10.1016/j.radonc.2017.03.021. Epub 2017 Apr 28.


Non-Small Cell Lung Cancer, Version 5.2017, NCCN Clinical Practice Guidelines in Oncology.

Ettinger DS, Wood DE, Aisner DL, Akerley W, Bauman J, Chirieac LR, D'Amico TA, DeCamp MM, Dilling TJ, Dobelbower M, Doebele RC, Govindan R, Gubens MA, Hennon M, Horn L, Komaki R, Lackner RP, Lanuti M, Leal TA, Leisch LJ, Lilenbaum R, Lin J, Loo BW Jr, Martins R, Otterson GA, Reckamp K, Riely GJ, Schild SE, Shapiro TA, Stevenson J, Swanson SJ, Tauer K, Yang SC, Gregory K, Hughes M.

J Natl Compr Canc Netw. 2017 Apr;15(4):504-535.


Optimal Radiation Therapy for Small Cell Lung Cancer.

Gensheimer MF, Loo BW Jr.

Curr Treat Options Oncol. 2017 Apr;18(4):21. doi: 10.1007/s11864-017-0467-z. Review.


Very high-energy electron (VHEE) beams in radiation therapy; Treatment plan comparison between VHEE, VMAT, and PPBS.

Schüler E, Eriksson K, Hynning E, Hancock SL, Hiniker SM, Bazalova-Carter M, Wong T, Le QT, Loo BW Jr, Maxim PG.

Med Phys. 2017 Jun;44(6):2544-2555. doi: 10.1002/mp.12233. Epub 2017 May 4.


Initial clinical outcomes of audiovisual-assisted therapeutic ambience in radiation therapy (AVATAR).

Hiniker SM, Bush K, Fowler T, White EC, Rodriguez S, Maxim PG, Donaldson SS, Loo BW Jr.

Pract Radiat Oncol. 2017 Sep - Oct;7(5):311-318. doi: 10.1016/j.prro.2017.01.007. Epub 2017 Jan 19.


Dynamic CT imaging of volumetric changes in pulmonary nodules correlates with physical measurements of stiffness.

Lartey FM, Rafat M, Negahdar M, Malkovskiy AV, Dong X, Sun X, Li M, Doyle T, Rajadas J, Graves EE, Loo BW, Maxim PG.

Radiother Oncol. 2017 Feb;122(2):313-318. doi: 10.1016/j.radonc.2016.11.019. Epub 2016 Dec 15.


Experimental Platform for Ultra-high Dose Rate FLASH Irradiation of Small Animals Using a Clinical Linear Accelerator.

Schüler E, Trovati S, King G, Lartey F, Rafat M, Villegas M, Praxel AJ, Loo BW Jr, Maxim PG.

Int J Radiat Oncol Biol Phys. 2017 Jan 1;97(1):195-203. doi: 10.1016/j.ijrobp.2016.09.018. Epub 2016 Sep 20.


Hypofractionated Intensity-Modulated Radiotherapy for Patients With Non-Small-Cell Lung Cancer.

Pollom EL, Qian Y, Durkee BY, von Eyben R, Maxim PG, Shultz DB, Gensheimer M, Diehn M, Loo BW Jr.

Clin Lung Cancer. 2016 Nov;17(6):588-594. doi: 10.1016/j.cllc.2016.05.024. Epub 2016 Jun 8.


Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance.

Jeong Y, Hoang NT, Lovejoy A, Stehr H, Newman AM, Gentles AJ, Kong W, Truong D, Martin S, Chaudhuri A, Heiser D, Zhou L, Say C, Carter JN, Hiniker SM, Loo BW Jr, West RB, Beachy P, Alizadeh AA, Diehn M.

Cancer Discov. 2017 Jan;7(1):86-101. doi: 10.1158/2159-8290.CD-16-0127. Epub 2016 Sep 23.


Metabolic tumor volume predicts overall survival and local control in patients with stage III non-small cell lung cancer treated in ACRIN 6668/RTOG 0235.

Bazan JG, Duan F, Snyder BS, Horng D, Graves EE, Siegel BA, Machtay M, Loo BW Jr.

Eur J Nucl Med Mol Imaging. 2017 Jan;44(1):17-24. Epub 2016 Sep 19.


Stereotactic Arrhythmia Radioablation (STAR) of Ventricular Tachycardia: A Treatment Planning Study.

Wang L, Fahimian B, Soltys SG, Zei P, Lo A, Gardner EA, Maguire PJ, Loo BW Jr.

Cureus. 2016 Jul 15;8(7):e694. doi: 10.7759/cureus.694.


A 3-D Riesz-Covariance Texture Model for Prediction of Nodule Recurrence in Lung CT.

Cirujeda P, Dicente Cid Y, Muller H, Rubin D, Aguilera TA, Loo BW, Diehn M, Binefa X, Depeursinge A.

IEEE Trans Med Imaging. 2016 Dec;35(12):2620-2630. doi: 10.1109/TMI.2016.2591921. Epub 2016 Jul 18.


NCCN Guidelines Insights: Malignant Pleural Mesothelioma, Version 3.2016.

Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D'Amico TA, Dilling T, Dobelbower M, Govindan R, Hennon M, Horn L, Jahan TM, Komaki R, Lackner RP, Lanuti M, Lilenbaum R, Lin J, Loo BW Jr, Martins R, Otterson GA, Patel JD, Pisters KM, Reckamp K, Riely GJ, Schild SE, Shapiro TA, Sharma N, Swanson SJ, Stevenson J, Tauer K, Yang SC, Gregory K, Hughes M.

J Natl Compr Canc Netw. 2016 Jul;14(7):825-36.


Pre-treatment non-target lung FDG-PET uptake predicts symptomatic radiation pneumonitis following Stereotactic Ablative Radiotherapy (SABR).

Chaudhuri AA, Binkley MS, Rigdon J, Carter JN, Aggarwal S, Dudley SA, Qian Y, Kumar KA, Hara WY, Gensheimer M, Nair VS, Maxim PG, Shultz DB, Bush K, Trakul N, Le QT, Diehn M, Loo BW Jr, Guo HH.

Radiother Oncol. 2016 Jun;119(3):454-60. doi: 10.1016/j.radonc.2016.05.007. Epub 2016 Jun 3.


The impact of audiovisual biofeedback on 4D functional and anatomic imaging: Results of a lung cancer pilot study.

Yang J, Yamamoto T, Pollock S, Berger J, Diehn M, Graves EE, Loo BW Jr, Keall PJ.

Radiother Oncol. 2016 Aug;120(2):267-72. doi: 10.1016/j.radonc.2016.05.016. Epub 2016 May 30.


Tracheal Diverticulum Following Paratracheal Hypofractionated Radiotherapy in the Setting of Prior and Subsequent Bevacizumab.

Chaudhuri AA, Chen JJ, Carter JN, Binkley MS, Kumar KA, Dudley SA, Sung AW, Loo BW Jr.

Cureus. 2016 Apr 19;8(4):e578. doi: 10.7759/cureus.578.


Robust Intratumor Partitioning to Identify High-Risk Subregions in Lung Cancer: A Pilot Study.

Wu J, Gensheimer MF, Dong X, Rubin DL, Napel S, Diehn M, Loo BW Jr, Li R.

Int J Radiat Oncol Biol Phys. 2016 Aug 1;95(5):1504-1512. doi: 10.1016/j.ijrobp.2016.03.018. Epub 2016 Mar 24.


Early-Stage Non-Small Cell Lung Cancer: Quantitative Imaging Characteristics of (18)F Fluorodeoxyglucose PET/CT Allow Prediction of Distant Metastasis.

Wu J, Aguilera T, Shultz D, Gudur M, Rubin DL, Loo BW Jr, Diehn M, Li R.

Radiology. 2016 Oct;281(1):270-8. doi: 10.1148/radiol.2016151829. Epub 2016 Apr 5.


Prognostic value of midtreatment FDG-PET in oropharyngeal cancer.

Pollom EL, Song J, Durkee BY, Aggarwal S, Bui T, von Eyben R, Li R, Brizel DM, Loo BW, Le QT, Hara WY.

Head Neck. 2016 Oct;38(10):1472-8. doi: 10.1002/hed.24454. Epub 2016 Apr 4.


Integrated digital error suppression for improved detection of circulating tumor DNA.

Newman AM, Lovejoy AF, Klass DM, Kurtz DM, Chabon JJ, Scherer F, Stehr H, Liu CL, Bratman SV, Say C, Zhou L, Carter JN, West RB, Sledge GW, Shrager JB, Loo BW Jr, Neal JW, Wakelee HA, Diehn M, Alizadeh AA.

Nat Biotechnol. 2016 May;34(5):547-555. doi: 10.1038/nbt.3520. Epub 2016 Mar 28.

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