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Items: 47


Experimental boundary conditions of reinstatement-induced return of fear in humans: Is reinstatement in humans what we think it is?

Sjouwerman R, Lonsdorf TB.

Psychophysiology. 2020 Feb 19:e13549. doi: 10.1111/psyp.13549. [Epub ahead of print]


Intolerance of uncertainty and threat generalization: A replication and extension.

Bauer EA, MacNamara A, Sandre A, Lonsdorf TB, Weinberg A, Morriss J, van Reekum CM.

Psychophysiology. 2020 Feb 14:e13546. doi: 10.1111/psyp.13546. [Epub ahead of print]


Navigating the garden of forking paths for data exclusions in fear conditioning research.

Lonsdorf TB, Klingelhöfer-Jens M, Andreatta M, Beckers T, Chalkia A, Gerlicher A, Jentsch VL, Meir Drexler S, Mertens G, Richter J, Sjouwerman R, Wendt J, Merz CJ.

Elife. 2019 Dec 16;8. pii: e52465. doi: 10.7554/eLife.52465.


Individual differences in human fear generalization-pattern identification and implications for anxiety disorders.

Stegmann Y, Schiele MA, Schümann D, Lonsdorf TB, Zwanzger P, Romanos M, Reif A, Domschke K, Deckert J, Gamer M, Pauli P.

Transl Psychiatry. 2019 Nov 18;9(1):307. doi: 10.1038/s41398-019-0646-8.


The Neurofunctional Basis of Affective Startle Modulation in Humans: Evidence From Combined Facial Electromyography and Functional Magnetic Resonance Imaging.

Kuhn M, Wendt J, Sjouwerman R, Büchel C, Hamm A, Lonsdorf TB.

Biol Psychiatry. 2020 Mar 15;87(6):548-558. doi: 10.1016/j.biopsych.2019.07.028. Epub 2019 Aug 6.


Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning.

Haaker J, Maren S, Andreatta M, Merz CJ, Richter J, Richter SH, Meir Drexler S, Lange MD, Jüngling K, Nees F, Seidenbecher T, Fullana MA, Wotjak CT, Lonsdorf TB.

Neurosci Biobehav Rev. 2019 Dec;107:329-345. doi: 10.1016/j.neubiorev.2019.09.020. Epub 2019 Sep 12. Review.


Fear Extinction Retention: Is It What We Think It Is?

Lonsdorf TB, Merz CJ, Fullana MA.

Biol Psychiatry. 2019 Jun 15;85(12):1074-1082. doi: 10.1016/j.biopsych.2019.02.011. Epub 2019 Feb 19.


Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes.

Gottschalk MG, Richter J, Ziegler C, Schiele MA, Mann J, Geiger MJ, Schartner C, Homola GA, Alpers GW, Büchel C, Fehm L, Fydrich T, Gerlach AL, Gloster AT, Helbig-Lang S, Kalisch R, Kircher T, Lang T, Lonsdorf TB, Pané-Farré CA, Ströhle A, Weber H, Zwanzger P, Arolt V, Romanos M, Wittchen HU, Hamm A, Pauli P, Reif A, Deckert J, Neufang S, Höfler M, Domschke K.

Transl Psychiatry. 2019 Feb 4;9(1):75. doi: 10.1038/s41398-019-0415-8.


Latency of skin conductance responses across stimulus modalities.

Sjouwerman R, Lonsdorf TB.

Psychophysiology. 2019 Apr;56(4):e13307. doi: 10.1111/psyp.13307. Epub 2018 Nov 21.


Does US expectancy mediate the additive effects of CS-US pairings on contingency instructions? Results from subjective, psychophysiological and neural measures.

Mertens G, Braem S, Kuhn M, Lonsdorf TB, van den Hout MA, Engelhard IM.

Behav Res Ther. 2018 Nov;110:41-46. doi: 10.1016/j.brat.2018.09.003. Epub 2018 Sep 8.


Visual Complexity and Affect: Ratings Reflect More Than Meets the Eye.

Madan CR, Bayer J, Gamer M, Lonsdorf TB, Sommer T.

Front Psychol. 2018 Jan 18;8:2368. doi: 10.3389/fpsyg.2017.02368. eCollection 2017.


An elevated plus-maze in mixed reality for studying human anxiety-related behavior.

Biedermann SV, Biedermann DG, Wenzlaff F, Kurjak T, Nouri S, Auer MK, Wiedemann K, Briken P, Haaker J, Lonsdorf TB, Fuss J.

BMC Biol. 2017 Dec 21;15(1):125. doi: 10.1186/s12915-017-0463-6.


Modulation of defensive reactivity by GLRB allelic variation: converging evidence from an intermediate phenotype approach.

Lueken U, Kuhn M, Yang Y, Straube B, Kircher T, Wittchen HU, Pfleiderer B, Arolt V, Wittmann A, Ströhle A, Weber H, Reif A, Domschke K, Deckert J, Lonsdorf TB.

Transl Psychiatry. 2017 Sep 5;7(9):e1227. doi: 10.1038/tp.2017.186.


More than just noise: Inter-individual differences in fear acquisition, extinction and return of fear in humans - Biological, experiential, temperamental factors, and methodological pitfalls.

Lonsdorf TB, Merz CJ.

Neurosci Biobehav Rev. 2017 Sep;80:703-728. doi: 10.1016/j.neubiorev.2017.07.007. Epub 2017 Jul 29. Review.


Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear.

Lonsdorf TB, Menz MM, Andreatta M, Fullana MA, Golkar A, Haaker J, Heitland I, Hermann A, Kuhn M, Kruse O, Meir Drexler S, Meulders A, Nees F, Pittig A, Richter J, Römer S, Shiban Y, Schmitz A, Straube B, Vervliet B, Wendt J, Baas JMP, Merz CJ.

Neurosci Biobehav Rev. 2017 Jun;77:247-285. doi: 10.1016/j.neubiorev.2017.02.026. Epub 2017 Mar 3. Review.


GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation: a potential neurogenetic pathway to panic disorder.

Deckert J, Weber H, Villmann C, Lonsdorf TB, Richter J, Andreatta M, Arias-Vasquez A, Hommers L, Kent L, Schartner C, Cichon S, Wolf C, Schaefer N, von Collenberg CR, Wachter B, Blum R, Schümann D, Scharfenort R, Schumacher J, Forstner AJ, Baumann C, Schiele MA, Notzon S, Zwanzger P, Janzing JGE, Galesloot T, Kiemeney LA, Gajewska A, Glotzbach-Schoon E, Mühlberger A, Alpers G, Fydrich T, Fehm L, Gerlach AL, Kircher T, Lang T, Ströhle A, Arolt V, Wittchen HU, Kalisch R, Büchel C, Hamm A, Nöthen MM, Romanos M, Domschke K, Pauli P, Reif A.

Mol Psychiatry. 2017 Oct;22(10):1431-1439. doi: 10.1038/mp.2017.2. Epub 2017 Feb 7.


Where There is Smoke There is Fear-Impaired Contextual Inhibition of Conditioned Fear in Smokers.

Haaker J, Lonsdorf TB, Schümann D, Bunzeck N, Peters J, Sommer T, Kalisch R.

Neuropsychopharmacology. 2017 Jul;42(8):1640-1646. doi: 10.1038/npp.2017.17. Epub 2017 Jan 25.


Don't startle me-Interference of startle probe presentations and intermittent ratings with fear acquisition.

Sjouwerman R, Niehaus J, Kuhn M, Lonsdorf TB.

Psychophysiology. 2016 Dec;53(12):1889-1899. doi: 10.1111/psyp.12761. Epub 2016 Sep 15.


State anxiety modulates the return of fear.

Kuhn M, Mertens G, Lonsdorf TB.

Int J Psychophysiol. 2016 Dec;110:194-199. doi: 10.1016/j.ijpsycho.2016.08.001. Epub 2016 Aug 3.


Converging evidence for an impact of a functional NOS gene variation on anxiety-related processes.

Kuhn M, Haaker J, Glotzbach-Schoon E, Schümann D, Andreatta M, Mechias ML, Raczka K, Gartmann N, Büchel C, Mühlberger A, Pauli P, Reif A, Kalisch R, Lonsdorf TB.

Soc Cogn Affect Neurosci. 2016 May;11(5):803-12. doi: 10.1093/scan/nsv151. Epub 2016 Jan 8.


Contextual Change After Fear Acquisition Affects Conditioned Responding and the Time Course of Extinction Learning-Implications for Renewal Research.

Sjouwerman R, Niehaus J, Lonsdorf TB.

Front Behav Neurosci. 2015 Dec 8;9:337. doi: 10.3389/fnbeh.2015.00337. eCollection 2015.


Neural correlates of and processes underlying generalized and differential return of fear.

Scharfenort R, Lonsdorf TB.

Soc Cogn Affect Neurosci. 2016 Apr;11(4):612-20. doi: 10.1093/scan/nsv142. Epub 2015 Nov 25.


Mismatch or allostatic load? Timing of life adversity differentially shapes gray matter volume and anxious temperament.

Kuhn M, Scharfenort R, Schümann D, Schiele MA, Münsterkötter AL, Deckert J, Domschke K, Haaker J, Kalisch R, Pauli P, Reif A, Romanos M, Zwanzger P, Lonsdorf TB.

Soc Cogn Affect Neurosci. 2016 Apr;11(4):537-47. doi: 10.1093/scan/nsv137. Epub 2015 Nov 13.


Effects of post-extinction l-DOPA administration on the spontaneous recovery and reinstatement of fear in a human fMRI study.

Haaker J, Lonsdorf TB, Kalisch R.

Eur Neuropsychopharmacol. 2015 Oct;25(10):1544-55. doi: 10.1016/j.euroneuro.2015.07.016. Epub 2015 Jul 21.


Deficient inhibitory processing in trait anxiety: Evidence from context-dependent fear learning, extinction recall and renewal.

Haaker J, Lonsdorf TB, Schümann D, Menz M, Brassen S, Bunzeck N, Gamer M, Kalisch R.

Biol Psychol. 2015 Oct;111:65-72. doi: 10.1016/j.biopsycho.2015.07.010. Epub 2015 Jul 26.


Sex differences in conditioned stimulus discrimination during context-dependent fear learning and its retrieval in humans: the role of biological sex, contraceptives and menstrual cycle phases.

Lonsdorf TB, Haaker J, Schümann D, Sommer T, Bayer J, Brassen S, Bunzeck N, Gamer M, Kalisch R.

J Psychiatry Neurosci. 2015 Nov;40(6):368-75.


Fear expression and return of fear following threat instruction with or without direct contingency experience.

Mertens G, Kuhn M, Raes AK, Kalisch R, De Houwer J, Lonsdorf TB.

Cogn Emot. 2016 Aug;30(5):968-84. doi: 10.1080/02699931.2015.1038219. Epub 2015 May 12.


A review on human reinstatement studies: an overview and methodological challenges.

Haaker J, Golkar A, Hermans D, Lonsdorf TB.

Learn Mem. 2014 Aug 15;21(9):424-40. doi: 10.1101/lm.036053.114. Print 2014 Sep. Review.


BDNFval66met affects neural activation pattern during fear conditioning and 24 h delayed fear recall.

Lonsdorf TB, Golkar A, Lindström KM, Haaker J, Öhman A, Schalling M, Ingvar M.

Soc Cogn Affect Neurosci. 2015 May;10(5):664-71. doi: 10.1093/scan/nsu102. Epub 2014 Aug 7.


Higher anxiety and larger amygdala volumes in carriers of a TMEM132D risk variant for panic disorder.

Haaker J, Lonsdorf TB, Raczka KA, Mechias ML, Gartmann N, Kalisch R.

Transl Psychiatry. 2014 Feb 4;4:e357. doi: 10.1038/tp.2014.1. No abstract available.


No evidence for enhanced extinction memory consolidation through noradrenergic reuptake inhibition-delayed memory test and reinstatement in human fMRI.

Lonsdorf TB, Haaker J, Fadai T, Kalisch R.

Psychopharmacology (Berl). 2014 May;231(9):1949-62. doi: 10.1007/s00213-013-3338-8. Epub 2013 Nov 6.


Multimodal assessment of long-term memory recall and reinstatement in a combined cue and context fear conditioning and extinction paradigm in humans.

Haaker J, Lonsdorf TB, Thanellou A, Kalisch R.

PLoS One. 2013 Oct 7;8(10):e76179. doi: 10.1371/journal.pone.0076179. eCollection 2013.


Attention biases and habituation of attention biases are associated with 5-HTTLPR and COMTval158met.

Lonsdorf TB, Juth P, Rohde C, Schalling M, Öhman A.

Cogn Affect Behav Neurosci. 2014 Mar;14(1):354-63. doi: 10.3758/s13415-013-0200-8.


Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear.

Haaker J, Gaburro S, Sah A, Gartmann N, Lonsdorf TB, Meier K, Singewald N, Pape HC, Morellini F, Kalisch R.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):E2428-36. doi: 10.1073/pnas.1303061110. Epub 2013 Jun 10.


Distinct contributions of the dorsolateral prefrontal and orbitofrontal cortex during emotion regulation.

Golkar A, Lonsdorf TB, Olsson A, Lindstrom KM, Berrebi J, Fransson P, Schalling M, Ingvar M, Öhman A.

PLoS One. 2012;7(11):e48107. doi: 10.1371/journal.pone.0048107. Epub 2012 Nov 7.


Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene.

Lindstedt F, Berrebi J, Greayer E, Lonsdorf TB, Schalling M, Ingvar M, Kosek E.

PLoS One. 2011 Mar 28;6(3):e18252. doi: 10.1371/journal.pone.0018252.


Perception of thermal pain and the thermal grill illusion is associated with polymorphisms in the serotonin transporter gene.

Lindstedt F, Lonsdorf TB, Schalling M, Kosek E, Ingvar M.

PLoS One. 2011 Mar 15;6(3):e17752. doi: 10.1371/journal.pone.0017752.


5-HTTLPR and COMTval158met genotype gate amygdala reactivity and habituation.

Lonsdorf TB, Golkar A, Lindstöm KM, Fransson P, Schalling M, Ohman A, Ingvar M.

Biol Psychol. 2011 Apr;87(1):106-12. doi: 10.1016/j.biopsycho.2011.02.014. Epub 2011 Feb 26.


The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder.

Lonsdorf TB, Rück C, Bergström J, Andersson G, Ohman A, Lindefors N, Schalling M.

BMC Psychiatry. 2010 Nov 26;10:99. doi: 10.1186/1471-244X-10-99.


Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism.

Lonsdorf TB, Weike AI, Golkar A, Schalling M, Hamm AO, Öhman A.

Behav Neurosci. 2010 Feb;124(1):9-15. doi: 10.1037/a0018261.


The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism.

Lonsdorf TB, Rück C, Bergström J, Andersson G, Ohman A, Schalling M, Lindefors N.

Prog Neuropsychopharmacol Biol Psychiatry. 2009 Nov 13;33(8):1479-83. doi: 10.1016/j.pnpbp.2009.08.004. Epub 2009 Aug 12. Erratum in: Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jan 15;35(1):312.


Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans.

Kosek E, Jensen KB, Lonsdorf TB, Schalling M, Ingvar M.

Mol Pain. 2009 Jul 1;5:37. doi: 10.1186/1744-8069-5-37.


Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val(158)met polymorphism.

Jensen KB, Lonsdorf TB, Schalling M, Kosek E, Ingvar M.

PLoS One. 2009 Jun 23;4(6):e6016. doi: 10.1371/journal.pone.0006016.


Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder.

Lonsdorf TB, Weike AI, Nikamo P, Schalling M, Hamm AO, Ohman A.

Psychol Sci. 2009 Feb;20(2):198-206. doi: 10.1111/j.1467-9280.2009.02280.x. Epub 2009 Jan 23.


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