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Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients.

Ozen G, Benyahia C, Amgoud Y, Patel J, Abd Elmoneim HM, Bouhadoun A, Yung S, Li F, Mahieddine Y, Silverstein AM, Castier Y, Cazes A, Longrois D, Clapp LH, Norel X.

Prostaglandins Other Lipid Mediat. 2019 Oct 28:106388. doi: 10.1016/j.prostaglandins.2019.106388. [Epub ahead of print]


Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension.

Ozen G, Benyahia C, Mani S, Boukais K, Silverstein AM, Bayles R, Nelsen AC, Castier Y, Danel C, Mal H, Clapp LH, Longrois D, Norel X.

Br J Pharmacol. 2019 Sep 2. doi: 10.1111/bph.14854. [Epub ahead of print]


Postoperative Cardiac Troponin I Thresholds Associated With 1-Year Cardiac Mortality After Adult Cardiac Surgery: An Attempt to Link Risk Stratification With Management Stratification in an Observational Study.

Provenchère S, Guglielminotti J, Gouel-Chéron A, Bresson E, Desplanque L, Bouleti C, Iung B, Montravers P, Dehoux M, Longrois D.

J Cardiothorac Vasc Anesth. 2019 Jul 2. pii: S1053-0770(19)30593-2. doi: 10.1053/j.jvca.2019.06.039. [Epub ahead of print]


An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis.

Jönsson F, de Chaisemartin L, Granger V, Gouel-Chéron A, Gillis CM, Zhu Q, Dib F, Nicaise-Roland P, Ganneau C, Hurtado-Nedelec M, Paugam-Burtz C, Necib S, Keita-Meyer H, Le Dorze M, Cholley B, Langeron O, Jacob L, Plaud B, Fischler M, Sauvan C, Guinnepain MT, Montravers P, Aubier M, Bay S, Neukirch C, Tubach F, Longrois D, Chollet-Martin S, Bruhns P.

Sci Transl Med. 2019 Jul 10;11(500). pii: eaat1479. doi: 10.1126/scitranslmed.aat1479.


The effect of local anesthetic continuous wound infusion for the prevention of postoperative pneumonia after on-pump cardiac surgery with sternotomy: the STERNOCAT randomized clinical trial.

Amour J, Cholley B, Ouattara A, Longrois D, Leprince P, Fellahi JL, Riou B, Hariri S, Latrémouille C, Rémy A, Provenchère S, Carillion A, Achouh P, Labrousse L, Tran Dinh A, Ait Hamou N, Charfeddine A, Lafourcade A, Hajage D, Bouglé A; STERNOCAT investigators.

Intensive Care Med. 2019 Jan;45(1):33-43. doi: 10.1007/s00134-018-5497-x. Epub 2019 Jan 7.


A quantified description of the interactions between the native cardiovascular system and femoro-femoral versus femoro-axillary extracorporeal life support using descending thoracic aorta velocity time integral.

Andrei S, Tran-Dinh A, Provenchere S, Lortat-Jacob B, Ghodbane W, Montravers P, Longrois D.

Artif Organs. 2019 Jul;43(7):647-655. doi: 10.1111/aor.13411. Epub 2019 Jan 28.


How to Manage Thrombocytopenia with ECLS: A Proposal of Clinical Reasoning Tools.

Koeltz A, Gendron N, Ajzenberg N, Longrois D.

J Extra Corpor Technol. 2018 Dec;50(4):256-259.


Streamlining pre- and intra-hospital care for patients with severe trauma: a white paper from the European Critical Care Foundation.

Longrois D, Maegele M, Bersini H, Crooks G, Hubloue I, Nowé A, Rimensberger PC, Sabbe M, Tilsed J, Vandemeulebroucke J, Verhelst W, Vincent JL.

Eur J Trauma Emerg Surg. 2019 Feb;45(1):39-48. doi: 10.1007/s00068-018-1053-1. Epub 2018 Dec 12. Review.


Inflammation increases MMP levels via PGE2 in human vascular wall and plasma of obese women.

Ozen G, Boumiza S, Deschildre C, Topal G, Longrois D, Jakobsson PJ, Michel JB, Jacob MP, Chahed K, Norel X.

Int J Obes (Lond). 2019 Sep;43(9):1724-1734. doi: 10.1038/s41366-018-0235-6. Epub 2018 Oct 22.


Peptide binding to cleaved CD31 dampens ischemia/reperfusion-induced intestinal injury.

Hoang QT, Nuzzo A, Louedec L, Delbosc S, Andreata F, Khallou-Laschet J, Assadi M, Montravers P, Longrois D, Corcos O, Caligiuri G, Nicoletti A, Michel JB, Tran-Dinh A.

Intensive Care Med Exp. 2018 Aug 15;6(1):27. doi: 10.1186/s40635-018-0192-3.


Safety and quality of procedural sedation and analgesia practice for adult patients throughout Europe: A step forward.

De Robertis E, Longrois D, Fuchs-Buder T.

Eur J Anaesthesiol. 2018 Jan;35(1):1-3. doi: 10.1097/EJA.0000000000000737. Review. No abstract available.


Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis.

Beutier H, Hechler B, Godon O, Wang Y, Gillis CM, de Chaisemartin L, Gouel-Chéron A, Magnenat S, Macdonald LE, Murphy AJ; NASA study group, Chollet-Martin S, Longrois D, Gachet C, Bruhns P, Jönsson F.

Sci Immunol. 2018 Apr 13;3(22). pii: eaan5997. doi: 10.1126/sciimmunol.aan5997.


Perioperative management of patients with coronary artery disease undergoing non-cardiac surgery: Summary from the French Society of Anaesthesia and Intensive Care Medicine 2017 convention.

Fellahi JL, Godier A, Benchetrit D, Berthier F, Besch G, Bochaton T, Bonnefoy-Cudraz E, Coriat P, Gayat E, Hong A, Jenck S, Le Gall A, Longrois D, Martin AC, Pili-Floury S, Piriou V, Provenchère S, Rozec B, Samain E, Schweizer R, Billard V.

Anaesth Crit Care Pain Med. 2018 Aug;37(4):367-374. doi: 10.1016/j.accpm.2018.02.021. Epub 2018 Mar 19. Review.


Is the EuroSCORE II reliable to estimate operative mortality among octogenarians?

Provenchère S, Chevalier A, Ghodbane W, Bouleti C, Montravers P, Longrois D, Iung B.

PLoS One. 2017 Nov 16;12(11):e0187056. doi: 10.1371/journal.pone.0187056. eCollection 2017.


Low end-tidal CO2 as a real-time severity marker of intra-anaesthetic acute hypersensitivity reactions.

Gouel-Chéron A, de Chaisemartin L, Jönsson F, Nicaise-Roland P, Granger V, Sabahov A, Guinnepain MT, Chollet-Martin S, Bruhns P, Neukirch C, Longrois D; NASA study group.

Br J Anaesth. 2017 Nov 1;119(5):908-917. doi: 10.1093/bja/aex260.


Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients: A Prospective Observational Study.

Guinot PG, Longrois D, Kamel S, Lorne E, Dupont H.

Crit Care Med. 2018 Jan;46(1):e17-e25. doi: 10.1097/CCM.0000000000002772.


Reference change values of plasma and urine NGAL in cardiac surgery with cardiopulmonary bypass.

Bataille A, Tiepolo A, Robert T, Boutten A, Longrois D, Dehoux M, Provenchère S.

Clin Biochem. 2017 Dec;50(18):1098-1103. doi: 10.1016/j.clinbiochem.2017.09.019. Epub 2017 Sep 23.


European Society of Anaesthesiology and European Board of Anaesthesiology guidelines for procedural sedation and analgesia in adults.

Hinkelbein J, Lamperti M, Akeson J, Santos J, Costa J, De Robertis E, Longrois D, Novak-Jankovic V, Petrini F, Struys MMRF, Veyckemans F, Fuchs-Buder T, Fitzgerald R.

Eur J Anaesthesiol. 2018 Jan;35(1):6-24. doi: 10.1097/EJA.0000000000000683. Review.


Comparison of three stimulation sites on the pupillary dilation reflex amplitude evoked by a standardized noxious test.

Roquet F, Guezouli L, Wachowska B, Balcan I, Montravers P, Longrois D, Guglielminotti J.

Anaesth Crit Care Pain Med. 2017 Dec;36(6):365-369. doi: 10.1016/j.accpm.2017.06.007. Epub 2017 Jul 26. No abstract available.


Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI2 : a safer alternative to COX-2 inhibition.

Ozen G, Gomez I, Daci A, Deschildre C, Boubaya L, Teskin O, Uydeş-Doğan BS, Jakobsson PJ, Longrois D, Topal G, Norel X.

Br J Pharmacol. 2017 Nov;174(22):4087-4098. doi: 10.1111/bph.13939. Epub 2017 Aug 11.


Epinephrine but not vasopressin attenuates the airway response to anaphylactic shock in rats.

Zheng F, Copotoiu R, Tacquard C, Demoulin B, Malinovsky JM, Levy B, Longrois D, Barthel G, Mertes PM, Marchal F, Demoulin-Alexikova S, Collange O.

Exp Lung Res. 2017 Apr;43(3):158-166. doi: 10.1080/01902148.2017.1323981. Epub 2017 May 25.


Decreased vasorelaxation induced by iloprost during acute inflammation in human internal mammary artery.

Foudi N, Ozen G, Amgoud Y, Louedec L, Choqueux C, Badi A, Kotelevets L, Chastre E, Longrois D, Norel X.

Eur J Pharmacol. 2017 Jun 5;804:31-37. doi: 10.1016/j.ejphar.2017.03.060. Epub 2017 Mar 31.


Interactions between veno-venous extracorporeal membrane oxygenation and cardiac function: an echocardiographic study upon weaning.

Guinot PG, Soulignac C, Zogheib E, Guilbart M, Abou-Arab O, Longrois D, Dupont H.

Br J Anaesth. 2016 Dec;117(6):821-822. No abstract available.


To streamline the guideline challenge: The European Society of Anaesthesiology policy on guidelines development.

De Robertis E, Longrois D.

Eur J Anaesthesiol. 2016 Nov;33(11):794-799. No abstract available.


The European Board of Anaesthesiology recommendations for safe medication practice: First update.

Whitaker D, Brattebø G, Trenkler S, Vanags I, Petrini F, Aykac Z, Longrois D, Loer SA, Gaszynski T, Sipylaite J, Copaciu E, Cerny V, Akeson J, Mellin-Olsen J, Abela C, Stecher A, Kozek-Langenecker S, Rätsep I; European Section and Board of Anaesthesiology of the UEMS.

Eur J Anaesthesiol. 2017 Jan;34(1):4-7.


Esmolol Corrects Severe Hypoxemia in Patients with Femoro-Femoral Venoarterial Extracorporeal Life Support for Lung Transplantation.

Ghalayini M, Brun PY, Augustin P, Guivarch E, Dilly MP, Provenchere S, Mordant P, Castier Y, Montravers P, Longrois D.

J Extra Corpor Technol. 2016 Sep;48(3):113-121.


Management of direct oral anticoagulants in patients undergoing elective surgeries and invasive procedures: Updated guidelines from the French Working Group on Perioperative Hemostasis (GIHP) - September 2015.

Albaladejo P, Bonhomme F, Blais N, Collet JP, Faraoni D, Fontana P, Godier A, Llau J, Longrois D, Marret E, Mismetti P, Rosencher N, Roullet S, Samama CM, Schved JF, Sié P, Steib A, Susen S; French Working Group on Perioperative Hemostasis (GIHP).

Anaesth Crit Care Pain Med. 2017 Feb;36(1):73-76. doi: 10.1016/j.accpm.2016.09.002. Epub 2016 Sep 20.


Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper.

Farmakis D, Alvarez J, Gal TB, Brito D, Fedele F, Fonseca C, Gordon AC, Gotsman I, Grossini E, Guarracino F, Harjola VP, Hellman Y, Heunks L, Ivancan V, Karavidas A, Kivikko M, Lomivorotov V, Longrois D, Masip J, Metra M, Morelli A, Nikolaou M, Papp Z, Parkhomenko A, Poelzl G, Pollesello P, Ravn HB, Rex S, Riha H, Ricksten SE, Schwinger RHG, Vrtovec B, Yilmaz MB, Zielinska M, Parissis J.

Int J Cardiol. 2016 Nov 1;222:303-312. doi: 10.1016/j.ijcard.2016.07.202. Epub 2016 Jul 29. Review.


Reverse Regulatory Pathway (H2S / PGE2 / MMP) in Human Aortic Aneurysm and Saphenous Vein Varicosity.

Gomez I, Ozen G, Deschildre C, Amgoud Y, Boubaya L, Gorenne I, Benyahia C, Roger T, Lesèche G, Galardon E, Topal G, Jacob MP, Longrois D, Norel X.

PLoS One. 2016 Jun 30;11(6):e0158421. doi: 10.1371/journal.pone.0158421. eCollection 2016.


The quest for the holy volume therapy.

De Robertis E, Afshari A, Longrois D.

Eur J Anaesthesiol. 2016 Jul;33(7):483-7. doi: 10.1097/EJA.0000000000000441. No abstract available.


Management of anaphylactic shock in the operating room.

Gouel-Chéron A, Harpan A, Mertes PM, Longrois D.

Presse Med. 2016 Sep;45(9):774-83. doi: 10.1016/j.lpm.2016.04.002. Epub 2016 May 18.


Comfort and patient-centred care without excessive sedation: the eCASH concept.

Vincent JL, Shehabi Y, Walsh TS, Pandharipande PP, Ball JA, Spronk P, Longrois D, Strøm T, Conti G, Funk GC, Badenes R, Mantz J, Spies C, Takala J.

Intensive Care Med. 2016 Jun;42(6):962-71. doi: 10.1007/s00134-016-4297-4. Epub 2016 Apr 13. Review.


Dexmedetomidine: Superiority trials needed?

Longrois D, Quintin L.

Anaesth Crit Care Pain Med. 2016 Jun;35(3):237-8. doi: 10.1016/j.accpm.2016.03.001. Epub 2016 Mar 10. No abstract available.


In Reply.

Guglielminotti J, Longrois D.

Anesthesiology. 2015 Dec;123(6):1481. doi: 10.1097/ALN.0000000000000897. No abstract available.


Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents.

Benyahia C, Ozen G, Orie N, Ledwozyw A, Louedec L, Li F, Senbel AM, Silverstein A, Danel C, Longrois D, Clapp LH, Norel X, Topal G.

Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt A):46-52. doi: 10.1016/j.prostaglandins.2015.09.002. Epub 2015 Sep 8.


Using Natriuretic Peptides for Selection of Patients in Acute Heart Failure Clinical Trials.

Smith SA, Mentz RJ, Roessig L, Mebazza A, Longrois D, Gheorghiade M, Pitt B, Zannad F, Butler J, Abraham WT.

Am J Cardiol. 2015 Oct 15;116(8):1304-10. doi: 10.1016/j.amjcard.2015.07.049. Epub 2015 Jul 29. Review.


Epinephrine, compared with arginine vasopressin, is associated with similar haemodynamic effects but significantly improved brain oxygenation in the early phase of anaphylactic shock in rats: An experimental study.

Zheng F, Collange O, Davidson J, Barthel G, Oulehri W, Thornton SN, Longrois D, Levy B, Audibert G, Malinovsky JM, Mertes PM.

Eur J Anaesthesiol. 2015 Aug;32(8):563-70. doi: 10.1097/EJA.0000000000000238.


Some Questioning About the Assessment of Renal Perfusion in Sepsis.

Guinot PG, Dupont H, Longrois D.

Crit Care Med. 2015 Jul;43(7):e262-4. doi: 10.1097/CCM.0000000000000961. No abstract available.


Agents with vasodilator properties in acute heart failure: how to design successful trials.

Mebazaa A, Longrois D, Metra M, Mueller C, Richards AM, Roessig L, Seronde MF, Sato N, Stockbridge NL, Gattis Stough W, Alonso A, Cody RJ, Cook Bruns N, Gheorghiade M, Holzmeister J, Laribi S, Zannad F.

Eur J Heart Fail. 2015 Jul;17(7):652-64. doi: 10.1002/ejhf.294. Epub 2015 Jun 4. Review.


Use of volatile anaesthetic agents in anaesthesia: A survey of practice in France in 2012.

Benhamou D, Constant I, Longrois D, Molliex S, Nouette-Gaulain K, Bull A.

Anaesth Crit Care Pain Med. 2015 Aug;34(4):205-9. doi: 10.1016/j.accpm.2015.01.006. Epub 2015 May 23.


Sedation options for the morbidly obese intensive care unit patient: a concise survey and an agenda for development.

Aantaa R, Tonner P, Conti G, Longrois D, Mantz J, Mulier JP.

Multidiscip Respir Med. 2015 Mar 7;10(1):8. doi: 10.1186/s40248-015-0007-2. eCollection 2015.


Prediction of movement to surgical stimulation by the pupillary dilatation reflex amplitude evoked by a standardized noxious test.

Guglielminotti J, Grillot N, Paule M, Mentré F, Servin F, Montravers P, Longrois D.

Anesthesiology. 2015 May;122(5):985-93. doi: 10.1097/ALN.0000000000000624.


Sedation in non-invasive ventilation: do we know what to do (and why)?

Longrois D, Conti G, Mantz J, Faltlhauser A, Aantaa R, Tonner P.

Multidiscip Respir Med. 2014 Nov 4;9(1):56. doi: 10.1186/2049-6958-9-56. eCollection 2014. Review.


Pregnancy in a Patient With Severe Aortic Stenosis Requiring Unusual Management.

Valeanu L, Depoix JP, Enguerand D, Tini L, Dilly MP, Raffoul R, Bourgeois-Moine A, Rajguru M, Longrois D, Iung B, Montravers P.

J Cardiothorac Vasc Anesth. 2015 Dec;29(6):1632-5. doi: 10.1053/j.jvca.2014.10.006. Epub 2015 Jan 31. No abstract available.


Anaphylactic bronchospasm during general anesthesia is not related to asthma.

Gouel-Chéron A, Neukirch C, Aubier B, Montravers P, Nicaise P, Chollet-Martin S, Mertes PM, Aubier M, Longrois D.

Allergy. 2015 Apr;70(4):453-6. doi: 10.1111/all.12565. Epub 2015 Jan 21.


[2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment andmanagement].

Kristensen SD, Knuuti J, Saraste A, Anker S, Bøtker HE, De Hert S, Ford I, Gonzalez-Juanatey JR, Gorenek B, Heyndrickx GR, Hoeft A, Huber K, Iung B, Kjeldsen KP, Longrois D, Lüscher TF, Pierard L, Pocock S, Price S, Roffi M, Sirnes PA, Sousa-Uva M, Voudris V, Funck-Brentano C.

Kardiol Pol. 2014;72(11):857-918. doi: 10.5603/KP.2014.0193. Polish. No abstract available.


Sedation and weaning from mechanical ventilation: time for 'best practice' to catch up with new realities?

Conti G, Mantz J, Longrois D, Tonner P.

Multidiscip Respir Med. 2014 Aug 29;9(1):45. doi: 10.1186/2049-6958-9-45. eCollection 2014. Review.


Reporting and Methodology of Multivariable Analyses in Prognostic Observational Studies Published in 4 Anesthesiology Journals: A Methodological Descriptive Review.

Guglielminotti J, Dechartres A, Mentré F, Montravers P, Longrois D, Laouénan C.

Anesth Analg. 2015 Oct;121(4):1011-29. doi: 10.1213/ANE.0000000000000517. Review.


Right ventricular systolic dysfunction and vena cava dilatation precede alteration of renal function in adult patients undergoing cardiac surgery: An observational study.

Guinot PG, Abou-Arab O, Longrois D, Dupont H.

Eur J Anaesthesiol. 2015 Aug;32(8):535-42. doi: 10.1097/EJA.0000000000000149.


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