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Best matches for Longpré J[au]:

The signaling signature of the neurotensin type 1 receptor with endogenous ligands. Besserer-Offroy É et al. Eur J Pharmacol. (2017)

Large Arachnoid Cyst. de Longpre J et al. N Engl J Med. (2017)

Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues. Fanelli R et al. J Med Chem. (2017)

Search results

Items: 1 to 50 of 57

1.

Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.

Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, Laporte SA.

Sci Signal. 2018 Dec 4;11(559). pii: eaat1631. doi: 10.1126/scisignal.aat1631.

PMID:
30514808
2.

Corrigendum to "Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings" [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320-2323].

Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S.

Bioorg Med Chem Lett. 2018 Nov 1;28(20):3418. doi: 10.1016/j.bmcl.2018.08.023. Epub 2018 Sep 5. No abstract available.

PMID:
30195888
3.

Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8-13).

Sousbie M, Vivancos M, Brouillette RL, Besserer-Offroy É, Longpré JM, Leduc R, Sarret P, Marsault É.

J Med Chem. 2018 Aug 23;61(16):7103-7115. doi: 10.1021/acs.jmedchem.8b00175. Epub 2018 Aug 13.

PMID:
30035538
4.

Evaluating Antimicrobial Use and Spectrum of Activity in Ontario Hospitals: Feasibility of a Multicentered Point Prevalence Study.

Leung V, Li M, Wu JH, Langford B, Zvonar R, Powis J, Longpre J, Béïque L, Gill S, Ho G, Garber G.

Open Forum Infect Dis. 2018 May 24;5(6):ofy110. doi: 10.1093/ofid/ofy110. eCollection 2018 Jun.

5.

Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings.

Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2320-2323. doi: 10.1016/j.bmcl.2018.05.015. Epub 2018 May 12. Erratum in: Bioorg Med Chem Lett. 2018 Nov 1;28(20):3418.

6.

In Search of the Optimal Macrocyclization Site for Neurotensin.

Sousbie M, Besserer-Offroy É, Brouillette RL, Longpré JM, Leduc R, Sarret P, Marsault É.

ACS Med Chem Lett. 2018 Jan 29;9(3):227-232. doi: 10.1021/acsmedchemlett.7b00500. eCollection 2018 Mar 8.

PMID:
29541365
7.

The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment.

Besserer-Offroy É, Bérubé P, Côté J, Murza A, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Marsault É, Sarret P.

Pharmacol Res. 2018 May;131:7-16. doi: 10.1016/j.phrs.2018.02.032. Epub 2018 Mar 9.

PMID:
29530600
8.

A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects.

Trân K, Murza A, Sainsily X, Coquerel D, Côté J, Belleville K, Haroune L, Longpré JM, Dumaine R, Salvail D, Lesur O, Auger-Messier M, Sarret P, Marsault É.

J Med Chem. 2018 Mar 22;61(6):2266-2277. doi: 10.1021/acs.jmedchem.7b01353. Epub 2018 Feb 26.

PMID:
29461833
9.

Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications.

Barrière DA, Noll C, Roussy G, Lizotte F, Kessai A, Kirby K, Belleville K, Beaudet N, Longpré JM, Carpentier AC, Geraldes P, Sarret P.

Sci Rep. 2018 Jan 11;8(1):424. doi: 10.1038/s41598-017-18896-5.

10.

Large Arachnoid Cyst.

de Longpre J.

N Engl J Med. 2017 Jun 8;376(23):2265. doi: 10.1056/NEJMicm1610483. No abstract available.

11.

Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues.

Fanelli R, Floquet N, Besserer-Offroy É, Delort B, Vivancos M, Longpré JM, Renault P, Martinez J, Sarret P, Cavelier F.

J Med Chem. 2017 Apr 27;60(8):3303-3313. doi: 10.1021/acs.jmedchem.6b01848. Epub 2017 Apr 10.

PMID:
28368584
12.

The signaling signature of the neurotensin type 1 receptor with endogenous ligands.

Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R.

Eur J Pharmacol. 2017 Jun 15;805:1-13. doi: 10.1016/j.ejphar.2017.03.046. Epub 2017 Mar 22.

PMID:
28341345
13.

Structure-activity relationship of novel macrocyclic biased apelin receptor agonists.

Murza A, Sainsily X, Côté J, Bruneau-Cossette L, Besserer-Offroy É, Longpré JM, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É.

Org Biomol Chem. 2017 Jan 4;15(2):449-458. doi: 10.1039/c6ob02247b.

PMID:
27924341
14.

Vagal stimulation targets select populations of intrinsic cardiac neurons to control neurally induced atrial fibrillation.

Salavatian S, Beaumont E, Longpré JP, Armour JA, Vinet A, Jacquemet V, Shivkumar K, Ardell JL.

Am J Physiol Heart Circ Physiol. 2016 Nov 1;311(5):H1311-H1320. doi: 10.1152/ajpheart.00443.2016. Epub 2016 Sep 2.

15.

Feed presentation options in Swine early fattening mitigates Salmonella shedding and specifically modulates the faecal microbiota.

Lebel P, Letellier A, Longpré J, Laplante B, Yergeau E, Fravalo P.

J Appl Microbiol. 2017 Jan;122(1):30-39. doi: 10.1111/jam.13305. Epub 2016 Dec 6.

PMID:
27684482
16.

Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2.

Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpré JM, Runyon SP, Decker AM, Gilmour BP, Sarret P.

ACS Chem Neurosci. 2016 Sep 21;7(9):1225-31. doi: 10.1021/acschemneuro.6b00097. Epub 2016 Jul 13.

PMID:
27359371
17.

Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain development.

Bégin-Lavallée V, Midavaine É, Dansereau MA, Tétreault P, Longpré JM, Jacobi AM, Rose SD, Behlke MA, Beaudet N, Sarret P.

Mol Pain. 2016 Jun 15;12. pii: 1744806916653969. doi: 10.1177/1744806916653969. Print 2016.

18.

Impact of mash feeding versus pellets on propionic/butyric acid levels and on total load in the gastrointestinal tract of growing pigs.

Longpré J, Fairbrother JM, Fravalo P, Arsenault J, LeBel P, Laplante B, Surprenant C, Massé D, Letellier A.

J Anim Sci. 2016 Mar;94(3):1053-63. doi: 10.2527/jas.2015-9617.

PMID:
27065267
19.

Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions.

Murza A, Sainsily X, Coquerel D, Côté J, Marx P, Besserer-Offroy É, Longpré JM, Lainé J, Reversade B, Salvail D, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É.

J Med Chem. 2016 Apr 14;59(7):2962-72. doi: 10.1021/acs.jmedchem.5b01549. Epub 2016 Mar 30.

PMID:
26986036
20.

Descending nociceptive inhibition is modulated in a time-dependent manner in a double-hit model of chronic/tonic pain.

Parent AJ, Tétreault P, Roux M, Belleville K, Longpré JM, Beaudet N, Goffaux P, Sarret P.

Neuroscience. 2016 Feb 19;315:70-8. doi: 10.1016/j.neuroscience.2015.11.065. Epub 2015 Dec 10.

PMID:
26691963
21.

Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues.

Fanelli R, Besserer-Offroy É, René A, Côté J, Tétreault P, Collerette-Tremblay J, Longpré JM, Leduc R, Martinez J, Sarret P, Cavelier F.

J Med Chem. 2015 Oct 8;58(19):7785-95. doi: 10.1021/acs.jmedchem.5b00841. Epub 2015 Sep 16.

PMID:
26348111
22.

The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2.

Thomas JB, Giddings AM, Olepu S, Wiethe RW, Warner KR, Sarret P, Longpre JM, Runyon SP, Gilmour BP.

Bioorg Med Chem Lett. 2015;25(10):2060-4. doi: 10.1016/j.bmcl.2015.03.083. Epub 2015 Apr 3.

23.

C-Terminal modifications of apelin-13 significantly change ligand binding, receptor signaling, and hypotensive action.

Murza A, Besserer-Offroy É, Côté J, Bérubé P, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Sarret P, Marsault É.

J Med Chem. 2015 Mar 12;58(5):2431-40. doi: 10.1021/jm501916k. Epub 2015 Feb 24.

PMID:
25668242
24.

Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2.

Thomas JB, Giddings AM, Olepu S, Wiethe RW, Harris DL, Narayanan S, Warner KR, Sarret P, Longpre JM, Runyon SP, Gilmour BP.

Bioorg Med Chem Lett. 2015 Jan 15;25(2):292-6. doi: 10.1016/j.bmcl.2014.11.047. Epub 2014 Nov 24.

25.

Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2.

Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP.

J Med Chem. 2014 Sep 11;57(17):7472-7. doi: 10.1021/jm500857r. Epub 2014 Aug 26.

26.

The transport mechanism of the human sodium/myo-inositol transporter 2 (SMIT2/SGLT6), a member of the LeuT structural family.

Sasseville LJ, Longpré JP, Wallendorff B, Lapointe JY.

Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C431-41. doi: 10.1152/ajpcell.00054.2014. Epub 2014 Jun 18.

27.

Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.

Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP.

J Med Chem. 2014 Jun 26;57(12):5318-32. doi: 10.1021/jm5003843. Epub 2014 Jun 5.

28.

Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid.

Murza A, Belleville K, Longpré JM, Sarret P, Marsault É.

Biopolymers. 2014 Jul;102(4):297-303. doi: 10.1002/bip.22498.

PMID:
24728860
29.

Measure of synchrony in the activity of intrinsic cardiac neurons.

Longpré JP, Salavatian S, Beaumont E, Armour JA, Ardell JL, Jacquemet V.

Physiol Meas. 2014 Apr;35(4):549-66. doi: 10.1088/0967-3334/35/4/549. Epub 2014 Mar 12.

30.

Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties.

Demeule M, Beaudet N, Régina A, Besserer-Offroy É, Murza A, Tétreault P, Belleville K, Ché C, Larocque A, Thiot C, Béliveau R, Longpré JM, Marsault É, Leduc R, Lachowicz JE, Gonias SL, Castaigne JP, Sarret P.

J Clin Invest. 2014 Mar;124(3):1199-213. doi: 10.1172/JCI70647. Epub 2014 Feb 17.

31.

Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family.

Longpré JP, Sasseville LJ, Lapointe JY.

J Gen Physiol. 2012 Oct;140(4):361-74.

32.

Inhibition by zinc of deoxycholate-induced apoptosis in HCT-116 cells.

Smith AF, Longpre J, Loo G.

J Cell Biochem. 2012 Feb;113(2):650-7. doi: 10.1002/jcb.23394.

PMID:
21975943
33.

Inhibition of deoxycholate-induced apoptosis in iron-depleted HCT-116 cells.

Longpre J, Loo G.

Apoptosis. 2012 Jan;17(1):70-8. doi: 10.1007/s10495-011-0655-4.

PMID:
21938477
34.

Determination of the Na(+)/glucose cotransporter (SGLT1) turnover rate using the ion-trap technique.

Longpré JP, Lapointe JY.

Biophys J. 2011 Jan 5;100(1):52-9. doi: 10.1016/j.bpj.2010.11.012.

35.

The actual ionic nature of the leak current through the Na+/glucose cotransporter SGLT1.

Longpré JP, Gagnon DG, Coady MJ, Lapointe JY.

Biophys J. 2010 Jan 20;98(2):231-9. doi: 10.1016/j.bpj.2009.10.015.

36.

10mM glucosamine prevents activation of proADAMTS5 (aggrecanase-2) in transfected cells by interference with post-translational modification of furin.

McCulloch DR, Wylie JD, Longpre JM, Leduc R, Apte SS.

Osteoarthritis Cartilage. 2010 Mar;18(3):455-63. doi: 10.1016/j.joca.2009.10.014. Epub 2009 Nov 4.

37.

Alternating carrier models and the energy conservation laws.

Lapointe JY, Sasseville LJ, Longpré JP.

Biophys J. 2009 Nov 4;97(9):2648-50. doi: 10.1016/j.bpj.2009.07.063. No abstract available.

38.

Characterization of proADAMTS5 processing by proprotein convertases.

Longpré JM, McCulloch DR, Koo BH, Alexander JP, Apte SS, Leduc R.

Int J Biochem Cell Biol. 2009 May;41(5):1116-26. doi: 10.1016/j.biocel.2008.10.008. Epub 2008 Nov 1.

PMID:
18992360
39.

Measuring ion transport activities in Xenopus oocytes using the ion-trap technique.

Blanchard MG, Longpré JP, Wallendorff B, Lapointe JY.

Am J Physiol Cell Physiol. 2008 Nov;295(5):C1464-72. doi: 10.1152/ajpcell.00560.2007. Epub 2008 Oct 1.

40.

Upregulation of GADD153 by butyrate: involvement of MAPK.

Scott DW, Longpre JM, Loo G.

DNA Cell Biol. 2008 Nov;27(11):607-14. doi: 10.1089/dna.2008.0773.

PMID:
18767967
41.

Protection of human colon epithelial cells against deoxycholate by rottlerin.

Longpre JM, Loo G.

Apoptosis. 2008 Sep;13(9):1162-71. doi: 10.1007/s10495-008-0244-3.

PMID:
18661240
42.

Paradoxical effect of diphenyleneiodonium in inducing DNA damage and apoptosis.

Longpre JM, Loo G.

Free Radic Res. 2008 Jun;42(6):533-43. doi: 10.1080/10715760802126692.

PMID:
18569011
43.

Regulation of ADAMTS9 secretion and enzymatic activity by its propeptide.

Koo BH, Longpré JM, Somerville RP, Alexander JP, Leduc R, Apte SS.

J Biol Chem. 2007 Jun 1;282(22):16146-54. Epub 2007 Apr 2.

44.

Inhibition of human matriptase by eglin c variants.

Désilets A, Longpré JM, Beaulieu ME, Leduc R.

FEBS Lett. 2006 Apr 17;580(9):2227-32. Epub 2006 Mar 20.

45.

Cell-surface processing of pro-ADAMTS9 by furin.

Koo BH, Longpré JM, Somerville RP, Alexander JP, Leduc R, Apte SS.

J Biol Chem. 2006 May 5;281(18):12485-94. Epub 2006 Mar 14.

46.

Stability of mutant serpin/furin complexes: dependence on pH and regulation at the deacylation step.

Dufour EK, Désilets A, Longpré JM, Leduc R.

Protein Sci. 2005 Feb;14(2):303-15.

47.

ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain.

Somerville RP, Longpré JM, Apel ED, Lewis RM, Wang LW, Sanes JR, Leduc R, Apte SS.

J Biol Chem. 2004 Aug 20;279(34):35159-75. Epub 2004 Jun 10.

48.

Identification of prodomain determinants involved in ADAMTS-1 biosynthesis.

Longpré JM, Leduc R.

J Biol Chem. 2004 Aug 6;279(32):33237-45. Epub 2004 Jun 7.

49.

Identification of furin pro-region determinants involved in folding and activation.

Bissonnette L, Charest G, Longpré JM, Lavigne P, Leduc R.

Biochem J. 2004 May 1;379(Pt 3):757-63.

50.

Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.

Somerville RP, Longpre JM, Jungers KA, Engle JM, Ross M, Evanko S, Wight TN, Leduc R, Apte SS.

J Biol Chem. 2003 Mar 14;278(11):9503-13. Epub 2003 Jan 3.

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