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Items: 37

1.

Two new cytotoxic linderazulenes from a deep-sea gorgonian of the genus Paramuricea.

Reddy NS, Reed JK, Longley RE, Wright AE.

J Nat Prod. 2005 Feb;68(2):248-50.

PMID:
15730254
2.

Lasonolides C-g, five new lasonolide compounds from the sponge Forcepia sp.

Wright AE, Chen Y, Winder PL, Pitts TP, Pomponi SA, Longley RE.

J Nat Prod. 2004 Aug;67(8):1351-5.

PMID:
15332854
3.

Plakolide A, a new gamma-lactone from the marine sponge Plakortis sp.

Gunasekera SP, Isbrucker RA, Longley RE, Wright AE, Pomponi SA, Reed JK.

J Nat Prod. 2004 Jan;67(1):110-1.

PMID:
14738400
4.

Discorhabdins S, T, and U, new cytotoxic pyrroloiminoquinones from a deep-water Caribbean sponge of the genus Batzella.

Gunasekera SP, Zuleta IA, Longley RE, Wright AE, Pomponi SA.

J Nat Prod. 2003 Dec;66(12):1615-7.

PMID:
14695808
5.

Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin.

Isbrucker RA, Cummins J, Pomponi SA, Longley RE, Wright AE.

Biochem Pharmacol. 2003 Jul 1;66(1):75-82.

PMID:
12818367
6.

Semisynthetic analogues of the microtubule-stabilizing agent discodermolide: preparation and biological activity.

Gunasekera SP, Longley RE, Isbrucker RA.

J Nat Prod. 2002 Dec;65(12):1830-7.

PMID:
12502323
7.

Five new discodermolide analogues from the marine sponge Discodermia species.

Gunasekera SP, Paul GK, Longley RE, Isbrucker RA, Pomponi SA.

J Nat Prod. 2002 Nov;65(11):1643-8.

PMID:
12444691
8.

Theopederins K and L. Highly potent cytotoxic metabolites from a marine sponge Discodermia species.

Paul GK, Gunasekera SP, Longley RE, Pomponi SA.

J Nat Prod. 2002 Jan;65(1):59-61.

PMID:
11809067
9.

Structure-activity relationship studies of discodermolide and its semisynthetic acetylated analogs on microtubule function and cytotoxicity.

Isbrucker RA, Gunasekera SP, Longley RE.

Cancer Chemother Pharmacol. 2001 Jul;48(1):29-36.

PMID:
11488521
10.

Acetylated analogues of the microtubule-stabilizing agent discodermolide: preparation and biological activity.

Gunasekera SP, Longley RE, Isbrucker RA.

J Nat Prod. 2001 Feb;64(2):171-4.

PMID:
11429994
11.

Secobatzellines A and B, two new enzyme inhibitors from a deep-water Caribbean sponge of the genus Batzella.

Gunasekera SP, McCarthy PJ, Longley RE, Pomponi SA, Wright AE.

J Nat Prod. 1999 Aug;62(8):1208-11.

PMID:
10479344
12.

Induction of apoptosis in mouse thymocytes by microcolin A and its synthetic analog.

Zhang LH, Longley RE.

Life Sci. 1999;64(12):1013-28.

PMID:
10210284
13.

Discorhabdin P, a new enzyme inhibitor from a deep-water Caribbean sponge of the genus Batzella.

Gunasekera SP, McCarthy PJ, Longley RE, Pomponi SA, Wright AE, Lobkovsky E, Clardy J.

J Nat Prod. 1999 Jan;62(1):173-5.

PMID:
9917313
15.
16.

A new cytotoxic sterol methoxymethyl ether from a deep water marine sponge Scleritoderma sp. cf. paccardi.

Gunasekera SP, Kelly-Borges M, Longley RE.

J Nat Prod. 1996 Feb;59(2):161-2.

PMID:
8991949
17.

Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.

ter Haar E, Kowalski RJ, Hamel E, Lin CM, Longley RE, Gunasekera SP, Rosenkranz HS, Day BW.

Biochemistry. 1996 Jan 9;35(1):243-50.

PMID:
8555181
18.

New cytotoxic peroxylactones from the marine sponge, Plakinastrella onkodes.

Horton PA, Longley RE, Kelly-Borges M, McConnell OJ, Ballas LM.

J Nat Prod. 1994 Oct;57(10):1374-81.

PMID:
7807122
19.

Analogues of the marine immunosuppressant microcolin A: preparation and biological activity.

Koehn FE, McConnell OJ, Longley RE, Sennett SH, Reed JK.

J Med Chem. 1994 Sep 16;37(19):3181-6.

PMID:
7932542
20.

Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian, Eudistoma sp.

Horton PA, Longley RE, McConnell OJ, Ballas LM.

Experientia. 1994 Sep 15;50(9):843-5.

PMID:
7925852
21.

The discovery of marine natural products with therapeutic potential.

McConnell OJ, Longley RE, Koehn FE.

Biotechnology. 1994;26:109-74. Review. No abstract available.

PMID:
7749302
22.

Immunosuppression by discodermolide.

Longley RE, Gunasekera SP, Faherty D, Mclane J, Dumont F.

Ann N Y Acad Sci. 1993 Nov 30;696:94-107. Review.

PMID:
8109858
23.

Evaluation of marine sponge metabolites for cytotoxicity and signal transduction activity.

Longley RE, McConnell OJ, Essich E, Harmody D.

J Nat Prod. 1993 Jun;56(6):915-20.

PMID:
8350092
24.

Microcolins A and B, new immunosuppressive peptides from the blue-green alga Lyngbya majuscula.

Koehn FE, Longley RE, Reed JK.

J Nat Prod. 1992 May;55(5):613-9.

PMID:
1517734
25.

Discodermolide--a new, marine-derived immunosuppressive compound. II. In vivo studies.

Longley RE, Caddigan D, Harmody D, Gunasekera M, Gunasekera SP.

Transplantation. 1991 Oct;52(4):656-61.

PMID:
1926345
26.

Discodermolide--a new, marine-derived immunosuppressive compound. I. In vitro studies.

Longley RE, Caddigan D, Harmody D, Gunasekera M, Gunasekera SP.

Transplantation. 1991 Oct;52(4):650-6. Erratum in: Transplantation 1993 Jan;55(1):236.

PMID:
1833864
27.
28.

Recovery of functional human lymphocytes from Leukotrap filters.

Longley RE, Stewart D.

J Immunol Methods. 1989 Jul 6;121(1):33-8.

PMID:
2754259
29.

Inhibition of murine lymphokine-activated killer (LAK) cell activity by adherent cells.

Longley RE, Stewart D, Roe KG, Good RA.

Cell Immunol. 1989 Jul;121(2):225-36.

PMID:
2786756
30.

Immunosuppressive compounds from a deep water marine sponge, Agelas flabelliformis.

Gunasekera SP, Cranick S, Longley RE.

J Nat Prod. 1989 Jul-Aug;52(4):757-61.

PMID:
2530314
31.
32.

Natural killer cells in the blood and bone marrow of the rhesus monkey.

Gengozian N, Longley RE, Filler J, Good RA.

Cell Immunol. 1986 Aug;101(1):24-38.

PMID:
3742605
33.

Characterization of a newly established feline lymphoma-derived cell line (BKD) lacking T and B cell surface markers.

Engelman RW, Machida K, Longley RE, Liu WT, Trang LQ, Good RA, Day NK.

In Vitro Cell Dev Biol. 1986 May;22(5):273-9.

PMID:
2423498
34.

The influence of dietary fat and non-specific immunotherapy on carcinogen-induced rat mammary adenocarcinoma.

Kollmorgen GM, King MM, Roszel JF, Daggs BJ, Longley RE.

Vet Pathol. 1981 Jan;18(1):82-91.

PMID:
6781126
35.

The methanol extraction residue of Bacillus Calmette-Guerin protects against 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinoma.

Kollmorgen GM, King MM, Lehman AA, Fischer G, Longley RE, Daggs BJ, Sansing WA.

Proc Soc Exp Biol Med. 1979 Dec;162(3):410-5. No abstract available.

PMID:
117451
36.
37.

Inhibition of lymphocyte function in rats fed higher-fat diets.

Kollmorgen GM, Sansing WA, Lehman AA, Fischer G, Longley RE, Alexander SS Jr, King MM, McCay PB.

Cancer Res. 1979 Sep;39(9):3458-62.

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