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Items: 40

1.

Keratin 6 is not essential for mammary gland development.

Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM.

Breast Cancer Res. 2006;8(3):R29. Epub 2006 Jun 21.

2.

Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity.

Caulin C, Nguyen T, Longley MA, Zhou Z, Wang XJ, Roop DR.

Cancer Res. 2004 Aug 1;64(15):5054-8.

4.

An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy.

Cao T, Longley MA, Wang XJ, Roop DR.

J Cell Biol. 2001 Feb 5;152(3):651-6.

5.

Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders.

Arin MJ, Longley MA, Wang XJ, Roop DR.

J Cell Biol. 2001 Feb 5;152(3):645-9.

6.

Transgenic mice expressing a mutant form of loricrin reveal the molecular basis of the skin diseases, Vohwinkel syndrome and progressive symmetric erythrokeratoderma.

Suga Y, Jarnik M, Attar PS, Longley MA, Bundman D, Steven AC, Koch PJ, Roop DR.

J Cell Biol. 2000 Oct 16;151(2):401-12.

7.

Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein.

Koch PJ, de Viragh PA, Scharer E, Bundman D, Longley MA, Bickenbach J, Kawachi Y, Suga Y, Zhou Z, Huber M, Hohl D, Kartasova T, Jarnik M, Steven AC, Roop DR.

J Cell Biol. 2000 Oct 16;151(2):389-400.

8.

Identification of a novel mutation in keratin 1 in a family with epidermolytic hyperkeratosis.

Arin MJ, Longley MA, Epstein EH Jr, Rothnagel JA, Roop DR.

Exp Dermatol. 2000 Feb;9(1):16-9.

PMID:
10688370
9.

The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.

Rothnagel JA, Seki T, Ogo M, Longley MA, Wojcik SM, Bundman DS, Bickenbach JR, Roop DR.

Differentiation. 1999 Oct;65(2):119-30.

PMID:
10550545
10.

Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.

Wojcik SM, Imakado S, Seki T, Longley MA, Petherbridge L, Bundman DS, Bickenbach JR, Rothnagel JA, Roop DR.

Differentiation. 1999 Oct;65(2):97-112.

PMID:
10550543
11.

Characterization of loricrin regulation in vitro and in transgenic mice.

DiSepio D, Bickenbach JR, Longley MA, Bundman DS, Rothnagel JA, Roop DR.

Differentiation. 1999 May;64(4):225-35.

PMID:
10365440
12.

An asparagine to threonine substitution in the 1A domain of keratin 1: a novel mutation that causes epidermolytic hyperkeratosis.

Arin MJ, Longley MA, Küster W, Huber M, Hohl D, Rothnagel JA, Roop DR.

Exp Dermatol. 1999 Apr;8(2):124-7.

PMID:
10232403
13.

A novel substitution in keratin 10 in epidermolytic hyperkeratosis.

Arin MJ, Longley MA, Anton-Lamprecht I, Kurze G, Huber M, Hohl D, Rothnagel JA, Roop DR.

J Invest Dermatol. 1999 Apr;112(4):506-8.

14.

A novel mutation in the 1A domain of keratin 2e in ichthyosis bullosa of Siemens.

Arin MJ, Longley MA, Epstein EH Jr, Scott G, Goldsmith LA, Rothnagel JA, Roop DR.

J Invest Dermatol. 1999 Mar;112(3):380-2.

15.

Prenatal diagnosis for keratin mutations to exclude transmission of epidermolytic hyperkeratosis.

Rothnagel JA, Lin MT, Longley MA, Holder RA, Hazen PG, Levy ML, Roop DR.

Prenat Diagn. 1998 Aug;18(8):826-30.

PMID:
9742571
16.

A novel dinucleotide mutation in keratin 10 in the annular epidermolytic ichthyosis variant of bullous congenital ichthyosiform erythroderma.

Joh GY, Traupe H, Metze D, Nashan D, Huber M, Hohl D, Longley MA, Rothnagel JA, Roop DR.

J Invest Dermatol. 1997 Mar;108(3):357-61.

17.

A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis.

Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA, Roop DR.

Differentiation. 1996 Dec;61(2):129-39.

PMID:
8983179
18.
19.

Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo.

Bonnekoh B, Greenhalgh DA, Bundman DS, Eckhardt JN, Longley MA, Chen SH, Woo SL, Roop DR.

J Invest Dermatol. 1995 Mar;104(3):313-7.

20.

Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3.

Rothnagel JA, Longley MA, Bundman DS, Naylor SL, Lalley PA, Jenkins NA, Gilbert DJ, Copeland NG, Roop DR.

Genomics. 1994 Sep 15;23(2):450-6.

PMID:
7835895
21.

Genetic disorders of keratin: are scarring alopecias a sub-set?

Rothnagel JA, Longley MA, Holder RA, Bundman DS, Seki T, Bickenbach JR, Roop DR.

J Dermatol Sci. 1994 Jul;7 Suppl:S164-9. Review.

PMID:
7528048
22.

Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.

Greenhalgh DA, Wang XJ, Rothnagel JA, Eckhardt JN, Quintanilla MI, Barber JL, Bundman DS, Longley MA, Schlegel R, Roop DR.

Cell Growth Differ. 1994 Jun;5(6):667-75.

23.

Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element.

Lu B, Rothnagel JA, Longley MA, Tsai SY, Roop DR.

J Biol Chem. 1994 Mar 11;269(10):7443-9.

24.

Prenatal diagnosis of epidermolytic hyperkeratosis by direct gene sequencing.

Rothnagel JA, Longley MA, Holder RA, Küster W, Roop DR.

J Invest Dermatol. 1994 Jan;102(1):13-6.

25.

Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas.

Dominey AM, Wang XJ, King LE Jr, Nanney LB, Gagne TA, Sellheyer K, Bundman DS, Longley MA, Rothnagel JA, Greenhalgh DA, et al.

Cell Growth Differ. 1993 Dec;4(12):1071-82.

26.

Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene.

Rothnagel JA, Greenhalgh DA, Gagne TA, Longley MA, Roop DR.

J Invest Dermatol. 1993 Oct;101(4):506-13.

27.

Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.

Greenhalgh DA, Rothnagel JA, Wang XJ, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C, Roop DR.

Oncogene. 1993 Aug;8(8):2145-57.

PMID:
7687760
28.

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.

Sellheyer K, Bickenbach JR, Rothnagel JA, Bundman D, Longley MA, Krieg T, Roche NS, Roberts AB, Roop DR.

Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5237-41.

29.

Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene.

Greenhalgh DA, Rothnagel JA, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Roop DR.

Mol Carcinog. 1993;7(2):99-110.

PMID:
7681293
30.

Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis.

Rothnagel JA, Dominey AM, Dempsey LD, Longley MA, Greenhalgh DA, Gagne TA, Huber M, Frenk E, Hohl D, Roop DR.

Science. 1992 Aug 21;257(5073):1128-30.

PMID:
1380725
31.

Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders.

Rothnagel JA, Longley MA, Bundman D, Greenhalgh DA, Dominey AM, Roop DR.

J Invest Dermatol. 1990 Nov;95(5 Suppl):59S-61S. Review.

32.

Identification of a major keratinocyte cell envelope protein, loricrin.

Mehrel T, Hohl D, Rothnagel JA, Longley MA, Bundman D, Cheng C, Lichti U, Bisher ME, Steven AC, Steinert PM, et al.

Cell. 1990 Jun 15;61(6):1103-12.

PMID:
2190691
33.

alpha-Fetoprotein and albumin gene expression in brain and other tissues of fetal and adult rats.

Sell S, Longley MA, Boulter J.

Brain Res. 1985 Sep;354(1):49-53.

PMID:
2412659
35.
36.

beta 2-Microglobulin clearance as measured by radioimmunoassay.

Woo J, Floyd M, Longley MA, Cannon DC.

Clin Chem. 1980 Jul;26(8):1193-7.

37.

Radioimmunoassay for immunologlobulin G in serum and urine.

Woo J, Floyd M, Longley MA, Cannon DC.

Clin Chem. 1979 Dec;25(12):2015-9.

38.

Patterns of hemoglobin assembly in reticulocytes of sickle cell trait individuals.

Shaeffer JR, Longley MA, DeSimone J, Kleve LJ.

J Biol Chem. 1975 Nov 25;250(22):8630-4.

39.

Unbalanced globin chain synthesis in reticulocytes of sickle cell trait individuals with low concentrations of hemoglobin S.

DeSimone J, Kleve L, Longley MA, Shaeffer J.

Biochem Biophys Res Commun. 1974 Jul 24;59(2):564-9. No abstract available.

PMID:
4855313
40.

Rapid turnover of newly-synthesized beta S chains in reticulocytes from individuals with sickle cell trait.

DeSimone J, Kleve L, Longley MA, Shaeffer J.

Biochem Biophys Res Commun. 1974 Mar 15;57(1):248-54. No abstract available.

PMID:
4828186

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