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Items: 1 to 50 of 64

1.

Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM.

Nature. 2019 Aug;572(7769):E18. doi: 10.1038/s41586-019-1459-x.

PMID:
31363232
2.

Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis.

Rothweiler S, Feldbrügge L, Jiang ZG, Csizmadia E, Longhi MS, Vaid K, Enjyoji K, Popov YV, Robson SC.

Purinergic Signal. 2019 Sep;15(3):375-385. doi: 10.1007/s11302-019-09664-3. Epub 2019 Jun 26.

PMID:
31243614
3.

Ectonucleotidases in Intestinal and Hepatic Inflammation.

Vuerich M, Robson SC, Longhi MS.

Front Immunol. 2019 Mar 19;10:507. doi: 10.3389/fimmu.2019.00507. eCollection 2019. Review.

4.

Dysregulation of Adenosinergic Signaling in Systemic and Organ-Specific Autoimmunity.

Vuerich M, Harshe RP, Robson SC, Longhi MS.

Int J Mol Sci. 2019 Jan 27;20(3). pii: E528. doi: 10.3390/ijms20030528. Review.

5.

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM.

Nature. 2018 Nov;563(7732):564-568. doi: 10.1038/s41586-018-0701-2. Epub 2018 Nov 7. Erratum in: Nature. 2019 Aug;572(7769):E18.

6.

HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease.

Xie A, Robles RJ, Mukherjee S, Zhang H, Feldbrügge L, Csizmadia E, Wu Y, Enjyoji K, Moss AC, Otterbein LE, Quintana FJ, Robson SC, Longhi MS.

J Autoimmun. 2018 Nov;94:122-133. doi: 10.1016/j.jaut.2018.07.022. Epub 2018 Aug 8.

PMID:
30098863
7.

The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis.

Peng ZW, Rothweiler S, Wei G, Ikenaga N, Liu SB, Sverdlov DY, Vaid KA, Longhi MS, Kuang M, Robson SC, Popov YV.

Hepatol Commun. 2017 Sep 26;1(9):957-972. doi: 10.1002/hep4.1084. eCollection 2017 Nov.

8.

Higher serum vitamin D levels are associated with protective serum cytokine profiles in patients with ulcerative colitis.

Gubatan J, Mitsuhashi S, Longhi MS, Zenlea T, Rosenberg L, Robson S, Moss AC.

Cytokine. 2018 Mar;103:38-45. doi: 10.1016/j.cyto.2017.12.023. Epub 2018 Jan 8.

9.

Regulatory T-cell conditioning endows activated effector T cells with suppressor function in autoimmune hepatitis/autoimmune sclerosing cholangitis.

Liberal R, Grant CR, Yuksel M, Graham J, Kalbasi A, Ma Y, Heneghan MA, Mieli-Vergani G, Vergani D, Longhi MS.

Hepatology. 2017 Nov;66(5):1570-1584. doi: 10.1002/hep.29307. Epub 2017 Oct 3.

10.

CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury.

Savio LEB, de Andrade Mello P, Figliuolo VR, de Avelar Almeida TF, Santana PT, Oliveira SDS, Silva CLM, Feldbrügge L, Csizmadia E, Minshall RD, Longhi MS, Wu Y, Robson SC, Coutinho-Silva R.

J Hepatol. 2017 Oct;67(4):716-726. doi: 10.1016/j.jhep.2017.05.021. Epub 2017 May 26.

11.

Purinergic signaling during intestinal inflammation.

Longhi MS, Moss A, Jiang ZG, Robson SC.

J Mol Med (Berl). 2017 Sep;95(9):915-925. doi: 10.1007/s00109-017-1545-1. Epub 2017 May 26. Review.

12.

Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohn's Disease.

Feldbrügge L, Moss AC, Yee EU, Csizmadia E, Mitsuhashi S, Longhi MS, Sandhu B, Stephan H, Wu Y, Cheifetz AS, Müller CE, Sévigny J, Robson SC, Jiang ZG.

J Crohns Colitis. 2017 Sep 1;11(9):1113-1123. doi: 10.1093/ecco-jcc/jjx058.

13.

Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.

Longhi MS, Vuerich M, Kalbasi A, Kenison JE, Yeste A, Csizmadia E, Vaughn B, Feldbrugge L, Mitsuhashi S, Wegiel B, Otterbein L, Moss A, Quintana FJ, Robson SC.

JCI Insight. 2017 May 4;2(9). pii: 92791. doi: 10.1172/jci.insight.92791. eCollection 2017 May 4.

14.

Deletion of Lactate Dehydrogenase-A in Myeloid Cells Triggers Antitumor Immunity.

Seth P, Csizmadia E, Hedblom A, Vuerich M, Xie H, Li M, Longhi MS, Wegiel B.

Cancer Res. 2017 Jul 1;77(13):3632-3643. doi: 10.1158/0008-5472.CAN-16-2938. Epub 2017 Apr 26.

15.

Novel high-throughput cell-based hybridoma screening methodology using the Celigo Image Cytometer.

Zhang H, Chan LL, Rice W, Kassam N, Longhi MS, Zhao H, Robson SC, Gao W, Wu Y.

J Immunol Methods. 2017 Aug;447:23-30. doi: 10.1016/j.jim.2017.04.003. Epub 2017 Apr 14.

16.

The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.

Allard B, Longhi MS, Robson SC, Stagg J.

Immunol Rev. 2017 Mar;276(1):121-144. doi: 10.1111/imr.12528. Review.

17.

Immunosuppressive drugs affect interferon (IFN)-γ and programmed cell death 1 (PD-1) kinetics in patients with newly diagnosed autoimmune hepatitis.

Grant CR, Holder BS, Liberal R, Heneghan MA, Ma Y, Mieli-Vergani G, Vergani D, Longhi MS.

Clin Exp Immunol. 2017 Jul;189(1):71-82. doi: 10.1111/cei.12956. Epub 2017 Mar 27.

18.

Phenotype and immune function of lymph node and peripheral blood CLL cells are linked to transendothelial migration.

Pasikowska M, Walsby E, Apollonio B, Cuthill K, Phillips E, Coulter E, Longhi MS, Ma Y, Yallop D, Barber LD, Patten P, Fegan C, Ramsay AG, Pepper C, Devereux S, Buggins AG.

Blood. 2016 Jul 28;128(4):563-73. doi: 10.1182/blood-2016-01-683128. Epub 2016 Jun 1.

19.

CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease.

Liberal R, Grant CR, Ma Y, Csizmadia E, Jiang ZG, Heneghan MA, Yee EU, Mieli-Vergani G, Vergani D, Robson SC, Longhi MS.

J Autoimmun. 2016 Aug;72:102-12. doi: 10.1016/j.jaut.2016.05.005. Epub 2016 May 20.

20.

In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression.

Liberal R, Grant CR, Holder BS, Cardone J, Martinez-Llordella M, Ma Y, Heneghan MA, Mieli-Vergani G, Vergani D, Longhi MS.

Hepatology. 2015 Sep;62(3):863-75. doi: 10.1002/hep.27884. Epub 2015 Jun 18.

PMID:
25953611
21.

Regulatory T cells: Mechanisms of suppression and impairment in autoimmune liver disease.

Liberal R, Grant CR, Longhi MS, Mieli-Vergani G, Vergani D.

IUBMB Life. 2015 Feb;67(2):88-97. doi: 10.1002/iub.1349. Epub 2015 Apr 8. Review.

22.

Regulatory T-cells in autoimmune diseases: challenges, controversies and--yet--unanswered questions.

Grant CR, Liberal R, Mieli-Vergani G, Vergani D, Longhi MS.

Autoimmun Rev. 2015 Feb;14(2):105-16. doi: 10.1016/j.autrev.2014.10.012. Epub 2014 Oct 16. Review. Erratum in: Autoimmun Rev. 2015 Sep;14(9):845-6.

PMID:
25449680
23.

Alginate microencapsulated hepatocytes optimised for transplantation in acute liver failure.

Jitraruch S, Dhawan A, Hughes RD, Filippi C, Soong D, Philippeos C, Lehec SC, Heaton ND, Longhi MS, Mitry RR.

PLoS One. 2014 Dec 1;9(12):e113609. doi: 10.1371/journal.pone.0113609. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119226.

24.

Autoimmune hepatitis.

Longhi MS, Mieli-Vergani G, Vergani D.

Curr Pediatr Rev. 2014;10(4):268-74. Review.

PMID:
25403636
25.

CD39 and CD161 modulate Th17 responses in Crohn's disease.

Bai A, Moss A, Kokkotou E, Usheva A, Sun X, Cheifetz A, Zheng Y, Longhi MS, Gao W, Wu Y, Robson SC.

J Immunol. 2014 Oct 1;193(7):3366-77. doi: 10.4049/jimmunol.1400346. Epub 2014 Aug 29.

26.

Reply: To PMID 23787765.

Grant CR, Liberal R, Ma Y, Robson SC, Mieli-Vergani G, Vergani D, Longhi MS.

Hepatology. 2015 Feb;61(2):737-8. doi: 10.1002/hep.27309. Epub 2015 Jan 5. No abstract available.

27.

Purinergic signaling in liver disease.

Vaughn BP, Robson SC, Longhi MS.

Dig Dis. 2014;32(5):516-24. doi: 10.1159/000360498. Epub 2014 Jul 14. Review.

28.

Vitamin D levels in adults with Crohn's disease are responsive to disease activity and treatment.

Ham M, Longhi MS, Lahiff C, Cheifetz A, Robson S, Moss AC.

Inflamm Bowel Dis. 2014 May;20(5):856-60. doi: 10.1097/MIB.0000000000000016.

29.

Retinoic acid stabilizes antigen-specific regulatory T-cell function in autoimmune hepatitis type 2.

Holder BS, Grant CR, Liberal R, Ma Y, Heneghan MA, Mieli-Vergani G, Vergani D, Longhi MS.

J Autoimmun. 2014 Sep;53:26-32. doi: 10.1016/j.jaut.2014.02.001. Epub 2014 Feb 22.

PMID:
24566085
30.

Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease.

Longhi MS, Moss A, Bai A, Wu Y, Huang H, Cheifetz A, Quintana FJ, Robson SC.

PLoS One. 2014 Feb 5;9(2):e87956. doi: 10.1371/journal.pone.0087956. eCollection 2014.

31.

Diagnostic criteria of autoimmune hepatitis.

Liberal R, Grant CR, Longhi MS, Mieli-Vergani G, Vergani D.

Autoimmun Rev. 2014 Apr-May;13(4-5):435-40. doi: 10.1016/j.autrev.2013.11.009. Epub 2014 Jan 10. Review.

PMID:
24418295
32.

Autoimmune Hepatitis: Clinical Review with Insights into the Purinergic Mechanism of Disease.

Kapila N, Higa JT, Longhi MS, Robson SC.

J Clin Transl Hepatol. 2013 Dec;1(2):79-86. doi: 10.14218/JCTH.2013.00015. Epub 2013 Dec 15. Review.

33.

Autoantibody and human leukocyte antigen profiles in children with autoimmune liver disease and their first-degree relatives.

Wang P, Su H, Underhill J, Blackmore LJ, Longhi MS, Grammatikopoulos T, Okokon EV, Davies ET, Vergani D, Mieli-Vergani G, Ma Y.

J Pediatr Gastroenterol Nutr. 2014 Apr;58(4):457-62. doi: 10.1097/MPG.0000000000000245.

PMID:
24231645
34.

The interplay between regulatory and effector T cells in autoimmune hepatitis: Implications for innovative treatment strategies.

Muratori L, Longhi MS.

J Autoimmun. 2013 Oct;46:74-80. doi: 10.1016/j.jaut.2013.06.016. Epub 2013 Jul 17. Review.

PMID:
23871639
35.

Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis.

Grant CR, Liberal R, Holder BS, Cardone J, Ma Y, Robson SC, Mieli-Vergani G, Vergani D, Longhi MS.

Hepatology. 2014 Mar;59(3):1007-15. doi: 10.1002/hep.26583. Epub 2014 Jan 30.

36.

Autoimmune hepatitis.

Heneghan MA, Yeoman AD, Verma S, Smith AD, Longhi MS.

Lancet. 2013 Oct 26;382(9902):1433-44. doi: 10.1016/S0140-6736(12)62163-1. Epub 2013 Jun 14. Review.

PMID:
23768844
37.

Biological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states.

Longhi MS, Robson SC, Bernstein SH, Serra S, Deaglio S.

J Mol Med (Berl). 2013 Feb;91(2):165-72. doi: 10.1007/s00109-012-0991-z. Epub 2013 Jan 6. Review.

38.

T-regs in autoimmune hepatitis-systemic lupus erythematosus/mixed connective tissue disease overlap syndrome are functionally defective and display a Th1 cytokine profile.

Longhi MS, Ma Y, Grant CR, Samyn M, Gordon P, Mieli-Vergani G, Vergani D.

J Autoimmun. 2013 Mar;41:146-51. doi: 10.1016/j.jaut.2012.12.003. Epub 2013 Jan 1.

PMID:
23287048
39.

CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel disease.

Doherty GA, Bai A, Hanidziar D, Longhi MS, Lawlor GO, Putheti P, Csizmadia E, Nowak M, Cheifetz AS, Moss AC, Robson SC.

Eur J Immunol. 2012 Nov;42(11):3062-72. doi: 10.1002/eji.201242623.

40.

Regulatory T cells in autoimmune hepatitis.

Longhi MS, Ma Y, Mieli-Vergani G, Vergani D.

J Hepatol. 2012 Oct;57(4):932-3; author reply 933-4. doi: 10.1016/j.jhep.2012.05.022. Epub 2012 Jun 27. No abstract available.

41.

Inhibition of interleukin-17 promotes differentiation of CD25⁻ cells into stable T regulatory cells in patients with autoimmune hepatitis.

Longhi MS, Liberal R, Holder B, Robson SC, Ma Y, Mieli-Vergani G, Vergani D.

Gastroenterology. 2012 Jun;142(7):1526-35.e6. doi: 10.1053/j.gastro.2012.02.041. Epub 2012 Feb 28.

PMID:
22387392
42.

The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway.

Liberal R, Grant CR, Holder BS, Ma Y, Mieli-Vergani G, Vergani D, Longhi MS.

Hepatology. 2012 Aug;56(2):677-86. doi: 10.1002/hep.25682. Epub 2012 Jul 6.

PMID:
22371007
43.

Pathogenesis of autoimmune hepatitis.

Liberal R, Longhi MS, Mieli-Vergani G, Vergani D.

Best Pract Res Clin Gastroenterol. 2011 Dec;25(6):653-64. doi: 10.1016/j.bpg.2011.09.009. Review.

PMID:
22117632
44.

Human CD4+CD25(high)CD127 (low/neg) regulatory T cells.

Su H, Longhi MS, Wang P, Vergani D, Ma Y.

Methods Mol Biol. 2012;806:287-99. doi: 10.1007/978-1-61779-367-7_20.

PMID:
22057460
45.

Autoimmune hepatitis after liver transplantation.

Liberal R, Longhi MS, Grant CR, Mieli-Vergani G, Vergani D.

Clin Gastroenterol Hepatol. 2012 Apr;10(4):346-53. doi: 10.1016/j.cgh.2011.10.028. Epub 2011 Nov 2. Review.

PMID:
22056300
46.

Autoantigen-specific regulatory T cells, a potential tool for immune-tolerance reconstitution in type-2 autoimmune hepatitis.

Longhi MS, Hussain MJ, Kwok WW, Mieli-Vergani G, Ma Y, Vergani D.

Hepatology. 2011 Feb;53(2):536-47. doi: 10.1002/hep.24039. Epub 2010 Dec 28.

PMID:
21274874
47.

Immune and viral profile from tolerance to hepatitis B surface antigen clearance: a longitudinal study of vertically hepatitis B virus-infected children on combined therapy.

Carey I, D'Antiga L, Bansal S, Longhi MS, Ma Y, Mesa IR, Mieli-Vergani G, Vergani D.

J Virol. 2011 Mar;85(5):2416-28. doi: 10.1128/JVI.01449-10. Epub 2010 Dec 8.

48.

A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis.

Ferri S, Longhi MS, De Molo C, Lalanne C, Muratori P, Granito A, Hussain MJ, Ma Y, Lenzi M, Mieli-Vergani G, Bianchi FB, Vergani D, Muratori L.

Hepatology. 2010 Sep;52(3):999-1007. doi: 10.1002/hep.23792.

PMID:
20683931
49.

Adaptive immunity in autoimmune hepatitis.

Longhi MS, Ma Y, Mieli-Vergani G, Vergani D.

Dig Dis. 2010;28(1):63-9. doi: 10.1159/000282066. Epub 2010 May 7. Review.

PMID:
20460892
50.

Review article: the modern management of autoimmune hepatitis.

Yeoman AD, Longhi MS, Heneghan MA.

Aliment Pharmacol Ther. 2010 Apr;31(8):771-87. doi: 10.1111/j.1365-2036.2010.04241.x. Epub 2010 Jan 19. Review.

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