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Items: 1 to 50 of 92

1.

Proteomic characterisation of the Chlamydia abortus outer membrane complex (COMC) using combined rapid monolithic column liquid chromatography and fast MS/MS scanning.

Longbottom D, Livingstone M, Aitchison KD, Imrie L, Manson E, Wheelhouse N, Inglis NF.

PLoS One. 2019 Oct 24;14(10):e0224070. doi: 10.1371/journal.pone.0224070. eCollection 2019.

2.

Abortion storm induced by the live C. abortus vaccine 1B strain in a vaccinated sheep flock, mimicking a natural wild-type infection.

Laroucau K, Aaziz R, Vorimore F, Menard MF, Longbottom D, Denis G.

Vet Microbiol. 2018 Nov;225:31-33. doi: 10.1016/j.vetmic.2018.09.012. Epub 2018 Sep 18.

PMID:
30322529
3.

Genomic evidence that the live Chlamydia abortus vaccine strain 1B is not attenuated and has the potential to cause disease.

Longbottom D, Sait M, Livingstone M, Laroucau K, Sachse K, Harris SR, Thomson NR, Seth-Smith HMB.

Vaccine. 2018 Jun 14;36(25):3593-3598. doi: 10.1016/j.vaccine.2018.05.042.

4.

Herd-level prevalence of selected endemic infectious diseases of dairy cows in Great Britain.

Velasova M, Damaso A, Prakashbabu BC, Gibbons J, Wheelhouse N, Longbottom D, Van Winden S, Green M, Guitian J.

J Dairy Sci. 2017 Nov;100(11):9215-9233. doi: 10.3168/jds.2016-11863. Epub 2017 Aug 23.

5.

Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS.

Livingstone M, Wheelhouse N, Ensor H, Rocchi M, Maley S, Aitchison K, Wattegedera S, Wilson K, Sait M, Siarkou V, Vretou E, Entrican G, Dagleish M, Longbottom D.

PLoS One. 2017 May 11;12(5):e0177653. doi: 10.1371/journal.pone.0177653. eCollection 2017.

6.

European Chlamydia abortus livestock isolate genomes reveal unusual stability and limited diversity, reflected in geographical signatures.

Seth-Smith HMB, Busó LS, Livingstone M, Sait M, Harris SR, Aitchison KD, Vretou E, Siarkou VI, Laroucau K, Sachse K, Longbottom D, Thomson NR.

BMC Genomics. 2017 May 4;18(1):344. doi: 10.1186/s12864-017-3657-y.

7.

Experimental challenge of pregnant cattle with the putative abortifacient Waddlia chondrophila.

Wheelhouse N, Flockhart A, Aitchison K, Livingstone M, Finlayson J, Flachon V, Sellal E, Dagleish MP, Longbottom D.

Sci Rep. 2016 Nov 14;6:37150. doi: 10.1038/srep37150.

8.

Ovine trophoblasts express cathelicidin host defence peptide in response to infection.

Coyle C, Wheelhouse N, Jacques M, Longbottom D, Svoboda P, Pohl J, Duncan WC, Rae MT, Barlow PG.

J Reprod Immunol. 2016 Sep;117:10-6. doi: 10.1016/j.jri.2016.06.006. Epub 2016 Jun 21.

9.

Analysis of Humoral Immune Responses to Surface and Virulence-Associated Chlamydia abortus Proteins in Ovine and Human Abortions by Use of a Newly Developed Line Immunoassay.

Hagemann JB, Simnacher U, Longbottom D, Livingstone M, Maile J, Soutschek E, Walder G, Boden K, Sachse K, Essig A.

J Clin Microbiol. 2016 Jul;54(7):1883-1890. doi: 10.1128/JCM.00351-16. Epub 2016 May 18.

10.

MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells.

Storrie S, Longbottom D, Barlow PG, Wheelhouse N.

PLoS One. 2016 Mar 22;11(3):e0152193. doi: 10.1371/journal.pone.0152193. eCollection 2016.

11.

Exposure to viral and bacterial pathogens among Soay sheep (Ovis aries) of the St Kilda archipelago.

Graham AL, Nussey DH, Lloyd-Smith JO, Longbottom D, Maley M, Pemberton JM, Pilkington JG, Prager KC, Smith L, Watt KA, Wilson K, McNEILLY TN, Brülisauer F.

Epidemiol Infect. 2016 Jul;144(9):1879-88. doi: 10.1017/S0950268816000017. Epub 2016 Feb 1.

12.

Late production of CXCL8 in ruminant oro-nasal turbinate cells in response to Chlamydia abortus infection.

Doull L, Wattegedera SR, Longbottom D, Mwangi D, Nath M, Glass EJ, Entrican G.

Vet Immunol Immunopathol. 2015 Nov 15;168(1-2):97-102. doi: 10.1016/j.vetimm.2015.08.011. Epub 2015 Aug 29.

13.

Improving the molecular diagnosis of Chlamydia psittaci and Chlamydia abortus infection with a species-specific duplex real-time PCR.

Opota O, Jaton K, Branley J, Vanrompay D, Erard V, Borel N, Longbottom D, Greub G.

J Med Microbiol. 2015 Oct;64(10):1174-85. doi: 10.1099/jmm.0.000139. Epub 2015 Jul 17.

14.

Diversification and Distribution of Ruminant Chlamydia abortus Clones Assessed by MLST and MLVA.

Siarkou VI, Vorimore F, Vicari N, Magnino S, Rodolakis A, Pannekoek Y, Sachse K, Longbottom D, Laroucau K.

PLoS One. 2015 May 22;10(5):e0126433. doi: 10.1371/journal.pone.0126433. eCollection 2015.

15.

Evidence of members of the Chlamydiales in bovine abortions in England and Wales.

Wheelhouse N, Mearns R, Willoughby K, Wright E, Turnbull D, Longbottom D.

Vet Rec. 2015 May 2;176(18):465. doi: 10.1136/vr.103075. Epub 2015 Apr 8. No abstract available.

PMID:
25854279
16.

Identification of the 1B vaccine strain of Chlamydia abortus in aborted placentas during the investigation of toxaemic and systemic disease in sheep.

Sargison ND, Truyers IG, Howie FE, Thomson JR, Cox AL, Livingstone M, Longbottom D.

N Z Vet J. 2015 Sep;63(5):284-7. doi: 10.1080/00480169.2015.1018365. Epub 2015 Jun 18.

PMID:
25695509
17.

Waddlia chondrophila infects and multiplies in ovine trophoblast cells stimulating an inflammatory immune response.

Wheelhouse N, Coyle C, Barlow PG, Mitchell S, Greub G, Baszler T, Rae MT, Longbottom D.

PLoS One. 2014 Jul 10;9(7):e102386. doi: 10.1371/journal.pone.0102386. eCollection 2014.

18.

Abortion in flocks vaccinated against enzootic abortion.

Livingstone M, Aitchison K, Longbottom D.

Vet Rec. 2014 Jun 14;174(24):613-4. doi: 10.1136/vr.g3833. No abstract available.

PMID:
24924971
19.

Chlamydia in cases of bovine abortion in Ireland.

Wheelhouse N, Longbottom D, O'Donovan J.

Vet Rec. 2014 May 31;174(22):560-1. doi: 10.1136/vr.g3567. No abstract available.

PMID:
24920716
20.

Genome sequencing and comparative analysis of three Chlamydia pecorum strains associated with different pathogenic outcomes.

Sait M, Livingstone M, Clark EM, Wheelhouse N, Spalding L, Markey B, Magnino S, Lainson FA, Myers GS, Longbottom D.

BMC Genomics. 2014 Jan 14;15:23. doi: 10.1186/1471-2164-15-23.

21.

Profiling antibody responses to infections by Chlamydia abortus enables identification of potential virulence factors and candidates for serodiagnosis.

Forsbach-Birk V, Foddis C, Simnacher U, Wilkat M, Longbottom D, Walder G, Benesch C, Ganter M, Sachse K, Essig A.

PLoS One. 2013 Nov 15;8(11):e80310. doi: 10.1371/journal.pone.0080310. eCollection 2013.

22.

Risk factors associated with Lawsonia intracellularis in English pig farms.

Bae JK, Wieland B, Sait M, Longbottom D, Smith DG, Alarcon P, Wheelhouse N.

Vet J. 2013 Sep;197(3):707-11. doi: 10.1016/j.tvjl.2013.03.020. Epub 2013 May 14.

PMID:
23683854
23.

Genome Sequence of Lawsonia intracellularis Strain N343, Isolated from a Sow with Hemorrhagic Proliferative Enteropathy.

Sait M, Aitchison K, Wheelhouse N, Wilson K, Lainson FA, Longbottom D, Smith DG.

Genome Announc. 2013 Jan;1(1). pii: e00027-13. doi: 10.1128/genomeA.00027-13. Epub 2013 Feb 28.

24.

Intranasal infection with Chlamydia abortus induces dose-dependent latency and abortion in sheep.

Longbottom D, Livingstone M, Maley S, van der Zon A, Rocchi M, Wilson K, Wheelhouse N, Dagleish M, Aitchison K, Wattegedera S, Nath M, Entrican G, Buxton D.

PLoS One. 2013;8(2):e57950. doi: 10.1371/journal.pone.0057950. Epub 2013 Feb 28.

25.

Genome Sequence of Chlamydia psittaci Strain 01DC12 Originating from Swine.

Seth-Smith HM, Sait M, Sachse K, Gaede W, Longbottom D, Thomson NR.

Genome Announc. 2013 Jan;1(1). pii: e00078-12. doi: 10.1128/genomeA.00078-12. Epub 2013 Jan 15.

26.

Chlamydia in cases of cattle pneumonia in Scotland.

Wheelhouse N, Longbottom D, Willoughby K.

Vet Rec. 2013 Jan 26;172(4):110. doi: 10.1136/vr.f469. No abstract available.

PMID:
23355717
27.

Processing of Chlamydia abortus polymorphic membrane protein 18D during the chlamydial developmental cycle.

Wheelhouse NM, Sait M, Aitchison K, Livingstone M, Wright F, McLean K, Inglis NF, Smith DG, Longbottom D.

PLoS One. 2012;7(11):e49190. doi: 10.1371/journal.pone.0049190. Epub 2012 Nov 8.

28.

Aldol reactions catalyzed by L-proline functionalized polymeric nanoreactors in water.

Lu A, Cotanda P, Patterson JP, Longbottom DA, O'Reilly RK.

Chem Commun (Camb). 2012 Oct 9;48(78):9699-701. doi: 10.1039/c2cc35170f.

PMID:
22911135
29.

Evaluation of the impact and control of enzootic abortion of ewes.

Longbottom D, Entrican G, Wheelhouse N, Brough H, Milne C.

Vet J. 2013 Feb;195(2):257-9. doi: 10.1016/j.tvjl.2012.06.018. Epub 2012 Jul 17.

PMID:
22809464
30.

Expression patterns of five polymorphic membrane proteins during the Chlamydia abortus developmental cycle.

Wheelhouse N, Sait M, Wilson K, Aitchison K, McLean K, Smith DG, Longbottom D.

Vet Microbiol. 2012 Dec 7;160(3-4):525-9. doi: 10.1016/j.vetmic.2012.06.017. Epub 2012 Jun 25.

31.

Involvement of Parachlamydia in bovine abortions in Scotland.

Wheelhouse N, Howie F, Gidlow J, Greub G, Dagleish M, Longbottom D.

Vet J. 2012 Aug;193(2):586-8. doi: 10.1016/j.tvjl.2012.01.008. Epub 2012 Feb 16.

PMID:
22341682
32.

Seroprevalence of chlamydial infection in cattle in Ireland.

Wilson K, Sammin D, Harmeyer S, Nath M, Livingstone M, Longbottom D.

Vet J. 2012 Aug;193(2):583-5. doi: 10.1016/j.tvjl.2011.12.018. Epub 2012 Jan 30.

PMID:
22285586
33.

New challenges for vaccination to prevent chlamydial abortion in sheep.

Entrican G, Wheelhouse N, Wattegedera SR, Longbottom D.

Comp Immunol Microbiol Infect Dis. 2012 May;35(3):271-6. doi: 10.1016/j.cimid.2011.12.001. Epub 2011 Dec 30. Review.

PMID:
22209689
34.

Endemic and emerging chlamydial infections of animals and their zoonotic implications.

Wheelhouse N, Longbottom D.

Transbound Emerg Dis. 2012 Aug;59(4):283-91. doi: 10.1111/j.1865-1682.2011.01274.x. Epub 2011 Nov 21. Review.

PMID:
22099945
35.

L-Proline Functionalized Polymers Prepared by RAFT Polymerization and Their Assemblies as Supported Organocatalysts.

Lu A, Smart TP, Epps TH 3rd, Longbottom DA, O'Reilly RK.

Macromolecules. 2011 Sep 27;44(18):7233-7241.

36.

Genome sequence of the Chlamydophila abortus variant strain LLG.

Sait M, Clark EM, Wheelhouse N, Livingstone M, Spalding L, Siarkou VI, Vretou E, Smith DG, Lainson FA, Longbottom D.

J Bacteriol. 2011 Aug;193(16):4276-7. doi: 10.1128/JB.05290-11. Epub 2011 Jun 17.

37.

Molecular detection of Chlamydia-like organisms in cattle drinking water.

Wheelhouse N, Sait M, Gidlow J, Deuchande R, Borel N, Baily J, Caldow G, Longbottom D.

Vet Microbiol. 2011 Aug 26;152(1-2):196-9. doi: 10.1016/j.vetmic.2011.03.040. Epub 2011 Apr 12.

PMID:
21549530
38.

Genetic variability of Chlamydophila abortus strains assessed by PCR-RFLP analysis of polymorphic membrane protein-encoding genes.

Sait M, Clark EM, Wheelhouse N, Spalding L, Livingstone M, Sachse K, Markey BK, Magnino S, Siarkou VI, Vretou E, Caro MR, Yaga R, Lainson FA, Smith DG, Wright F, Longbottom D.

Vet Microbiol. 2011 Aug 5;151(3-4):284-90. doi: 10.1016/j.vetmic.2011.03.005. Epub 2011 Mar 10.

PMID:
21511408
39.

Identification, sequencing and molecular analysis of Chp4, a novel chlamydiaphage of Chlamydophila abortus belonging to the family Microviridae.

Sait M, Livingstone M, Graham R, Inglis NF, Wheelhouse N, Longbottom D.

J Gen Virol. 2011 Jul;92(Pt 7):1733-7. doi: 10.1099/vir.0.031583-0. Epub 2011 Mar 30.

PMID:
21450942
40.

Treatment and control of chlamydial and rickettsial infections in sheep and goats.

Stuen S, Longbottom D.

Vet Clin North Am Food Anim Pract. 2011 Mar;27(1):213-233. doi: 10.1016/j.cvfa.2010.10.017. Epub 2010 Dec 13. Review.

PMID:
21215905
41.

Ectopic lymphoid tissue formation in the lungs of mice infected with Chlamydia pneumoniae is associated with epithelial macrophage inflammatory protein-2/CXCL2 expression.

Fitch PM, Wheelhouse NM, Bowles P, Paterson M, Longbottom D, Entrican G, Howie SE.

Clin Exp Immunol. 2010 Nov;162(2):372-8. doi: 10.1111/j.1365-2249.2010.04231.x. Epub 2010 Sep 14.

42.

Novel chlamydia-like organisms as cause of bovine abortions, UK.

Wheelhouse N, Katzer F, Wright F, Longbottom D.

Emerg Infect Dis. 2010 Aug;16(8):1323-4. doi: 10.3201/eid1608.091878. No abstract available.

43.

Evidence of Chlamydophila abortus vaccine strain 1B as a possible cause of ovine enzootic abortion.

Wheelhouse N, Aitchison K, Laroucau K, Thomson J, Longbottom D.

Vaccine. 2010 Aug 9;28(35):5657-63. doi: 10.1016/j.vaccine.2010.04.114.

PMID:
20554095
44.

Parachlamydia involvement in bovine abortions in a beef herd in Scotland.

Deuchande R, Gidlow J, Caldow G, Baily J, Longbottom D, Wheelhouse N, Borel N, Greub G.

Vet Rec. 2010 May 8;166(19):598-9. doi: 10.1136/vr.c2435. No abstract available.

PMID:
20453242
45.

Inflammatory cytokine responses in a pregnant mouse model of Chlamydophila abortus infection.

Kerr K, Wheelhouse N, Livingstone M, Anderson IE, Entrican G, McKeever D, Longbottom D.

Vet Microbiol. 2010 Aug 26;144(3-4):392-8. doi: 10.1016/j.vetmic.2010.01.025. Epub 2010 Feb 4.

PMID:
20181442
46.

Transcriptional analysis of in vitro expression patterns of Chlamydophila abortus polymorphic outer membrane proteins during the chlamydial developmental cycle.

Wheelhouse N, Aitchison K, Spalding L, Livingstone M, Longbottom D.

Vet Res. 2009 Sep-Oct;40(5):47. doi: 10.1051/vetres/2009030. Epub 2009 May 21.

47.

Ovine trophoblast is a primary source of TNFalpha during Chlamydophila abortus infection.

Wheelhouse N, Wattegedera S, Stanton J, Maley S, Watson D, Jepson C, Deane D, Buxton D, Longbottom D, Baszler T, Entrican G.

J Reprod Immunol. 2009 Jun;80(1-2):49-56. doi: 10.1016/j.jri.2008.12.003. Epub 2009 Apr 9.

PMID:
19361867
48.

Chlamydioses. Preface.

Sachse K, Longbottom D, Pospischil A.

Vet Microbiol. 2009 Mar 16;135(1-2):1. doi: 10.1016/j.vetmic.2008.09.039. Epub 2008 Sep 16. No abstract available.

PMID:
19246165
49.

Genotyping of Chlamydophila abortus strains by multilocus VNTR analysis.

Laroucau K, Vorimore F, Bertin C, Mohamad KY, Thierry S, Hermann W, Maingourd C, Pourcel C, Longbottom D, Magnino S, Sachse K, Vretou E, Rodolakis A.

Vet Microbiol. 2009 Jun 12;137(3-4):335-44. doi: 10.1016/j.vetmic.2009.01.029. Epub 2009 Jan 24.

PMID:
19217221
50.

Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation for use in natural product synthesis.

Evans AC, Longbottom DA, Matsuoka M, Davies JE, Turner R, Franckevicius V, Ley SV.

Org Biomol Chem. 2009 Feb 21;7(4):747-60. doi: 10.1039/b813494d. Epub 2009 Jan 6.

PMID:
19194591

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