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Items: 45


Single-Cell Analysis Reveals that Chronic Silver Nanoparticle Exposure Induces Cell Division Defects in Human Epithelial Cells.

Garcia EB, Alms C, Hinman AW, Kelly C, Smith A, Vance M, Loncarek J, Marr LC, Cimini D.

Int J Environ Res Public Health. 2019 Jun 11;16(11). pii: E2061. doi: 10.3390/ijerph16112061.


Regulation of cilia abundance in multiciliated cells.

Nanjundappa R, Kong D, Shim K, Stearns T, Brody SL, Loncarek J, Mahjoub MR.

Elife. 2019 Apr 26;8. pii: e44039. doi: 10.7554/eLife.44039.


High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy.

Bowler M, Kong D, Sun S, Nanjundappa R, Evans L, Farmer V, Holland A, Mahjoub MR, Sui H, Loncarek J.

Nat Commun. 2019 Mar 1;10(1):993. doi: 10.1038/s41467-018-08216-4.


PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formation.

Montenegro Gouveia S, Zitouni S, Kong D, Duarte P, Ferreira Gomes B, Sousa AL, Tranfield EM, Hyman A, Loncarek J, Bettencourt-Dias M.

J Cell Sci. 2018 Nov 9;132(4). pii: jcs219501. doi: 10.1242/jcs.219501.


Separation and Loss of Centrioles From Primordidal Germ Cells To Mature Oocytes In The Mouse.

Simerly C, Manil-Ségalen M, Castro C, Hartnett C, Kong D, Verlhac MH, Loncarek J, Schatten G.

Sci Rep. 2018 Aug 24;8(1):12791. doi: 10.1038/s41598-018-31222-x.


Author Correction: A novel atypical sperm centriole is functional during human fertilization.

Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller AL, Simerly C, Schatten G, Loncarek J, Mennella V, Avidor-Reiss T.

Nat Commun. 2018 Jul 13;9(1):2800. doi: 10.1038/s41467-018-05324-z.


Direct molecular dissection of tumor parenchyma from tumor stroma in tumor xenograft using mass spectrometry-based glycoproteomics.

Ye X, Luke BT, Wei BR, Kaczmarczyk JA, Loncarek J, Dwyer JE, Johann DJ, Saul RG, Nissley DV, McCormick F, Whiteley GR, Blonder J.

Oncotarget. 2018 May 29;9(41):26431-26452. doi: 10.18632/oncotarget.25449. eCollection 2018 May 29.


A novel atypical sperm centriole is functional during human fertilization.

Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller AL, Simerly C, Schatten G, Loncarek J, Mennella V, Avidor-Reiss T.

Nat Commun. 2018 Jun 7;9(1):2210. doi: 10.1038/s41467-018-04678-8. Erratum in: Nat Commun. 2018 Jul 13;9(1):2800.


Building the right centriole for each cell type.

Loncarek J, Bettencourt-Dias M.

J Cell Biol. 2018 Mar 5;217(3):823-835. doi: 10.1083/jcb.201704093. Epub 2017 Dec 28. Review.


Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.

Wang JT, Kong D, Hoerner CR, Loncarek J, Stearns T.

Elife. 2017 Sep 14;6. pii: e29061. doi: 10.7554/eLife.29061.


Cyanine Conformational Restraint in the Far-Red Range.

Michie MS, Götz R, Franke C, Bowler M, Kumari N, Magidson V, Levitus M, Loncarek J, Sauer M, Schnermann MJ.

J Am Chem Soc. 2017 Sep 13;139(36):12406-12409. doi: 10.1021/jacs.7b07272. Epub 2017 Sep 1.


Centriole Remodeling during Spermiogenesis in Drosophila.

Khire A, Jo KH, Kong D, Akhshi T, Blachon S, Cekic AR, Hynek S, Ha A, Loncarek J, Mennella V, Avidor-Reiss T.

Curr Biol. 2016 Dec 5;26(23):3183-3189. doi: 10.1016/j.cub.2016.07.006. Epub 2016 Oct 27.


Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.

Ye X, Chan KC, Waters AM, Bess M, Harned A, Wei BR, Loncarek J, Luke BT, Orsburn BC, Hollinger BD, Stephens RM, Bagni R, Martinko A, Wells JA, Nissley DV, McCormick F, Whiteley G, Blonder J.

Oncotarget. 2016 Dec 27;7(52):86948-86971. doi: 10.18632/oncotarget.13566.


BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.

Thirthagiri E, Klarmann KD, Shukla AK, Southon E, Biswas K, Martin BK, North SL, Magidson V, Burkett S, Haines DC, Noer K, Matthai R, Tessarollo L, Loncarek J, Keller JR, Sharan SK.

Hum Mol Genet. 2016 May 15;25(10):1934-1945. Epub 2016 Feb 26.


MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.

Van de Mark D, Kong D, Loncarek J, Stearns T.

Mol Biol Cell. 2015 Nov 1;26(21):3788-802. doi: 10.1091/mbc.E15-04-0235. Epub 2015 Sep 2.


Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation.

Shukla A, Kong D, Sharma M, Magidson V, Loncarek J.

Nat Commun. 2015 Aug 21;6:8077. doi: 10.1038/ncomms9077.


Correlative light and electron microscopy analysis of the centrosome: A step-by-step protocol.

Kong D, Loncarek J.

Methods Cell Biol. 2015;129:1-18. doi: 10.1016/bs.mcb.2015.03.013. Epub 2015 May 27.


[Croatian Medical Association--Branch Rijeka].

Bakašun V, Lončarek J.

Lijec Vjesn. 2014 Nov-Dec;136(11-12):382-4. Croatian.


Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration.

Kumar A, Lualdi M, Lyozin GT, Sharma P, Loncarek J, Fu XY, Kuehn MR.

Dev Biol. 2015 Apr 1;400(1):1-9. doi: 10.1016/j.ydbio.2014.12.016. Epub 2014 Dec 20.


Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles.

Kong D, Farmer V, Shukla A, James J, Gruskin R, Kiriyama S, Loncarek J.

J Cell Biol. 2014 Sep 29;206(7):855-65. doi: 10.1083/jcb.201407087. Epub 2014 Sep 22.


CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells.

Jia J, Bosley AD, Thompson A, Hoskins JW, Cheuk A, Collins I, Parikh H, Xiao Z, Ylaya K, Dzyadyk M, Cozen W, Hernandez BY, Lynch CF, Loncarek J, Altekruse SF, Zhang L, Westlake CJ, Factor VM, Thorgeirsson S, Bamlet WR, Hewitt SM, Petersen GM, Andresson T, Amundadottir LT.

Cancer Res. 2014 May 15;74(10):2785-95. doi: 10.1158/0008-5472.CAN-13-3176. Epub 2014 Mar 19.


Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development.

Kumar A, Lualdi M, Loncarek J, Cho YW, Lee JE, Ge K, Kuehn MR.

Dev Dyn. 2014 Jul;243(7):937-47. doi: 10.1002/dvdy.24125. Epub 2014 Apr 17.


Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152.

Kim TS, Park JE, Shukla A, Choi S, Murugan RN, Lee JH, Ahn M, Rhee K, Bang JK, Kim BY, Loncarek J, Erikson RL, Lee KS.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4849-57. doi: 10.1073/pnas.1319656110. Epub 2013 Nov 25.


Predictive-focus illumination for reducing photodamage in live-cell microscopy.

Schilling Z, Frank E, Magidson V, Wason J, Lončarek J, Boyer K, Wen J, Khodjakov A.

J Microsc. 2012 May;246(2):160-7. doi: 10.1111/j.1365-2818.2012.03605.x. Epub 2012 Mar 20.


Concerted effort of centrosomal and Golgi-derived microtubules is required for proper Golgi complex assembly but not for maintenance.

Vinogradova T, Paul R, Grimaldi AD, Loncarek J, Miller PM, Yampolsky D, Magidson V, Khodjakov A, Mogilner A, Kaverina I.

Mol Biol Cell. 2012 Mar;23(5):820-33. doi: 10.1091/mbc.E11-06-0550. Epub 2012 Jan 19.


The spatial arrangement of chromosomes during prometaphase facilitates spindle assembly.

Magidson V, O'Connell CB, Lončarek J, Paul R, Mogilner A, Khodjakov A.

Cell. 2011 Aug 19;146(4):555-67. doi: 10.1016/j.cell.2011.07.012.


Centriole reduplication during prolonged interphase requires procentriole maturation governed by Plk1.

Loncarek J, Hergert P, Khodjakov A.

Curr Biol. 2010 Jul 27;20(14):1277-82. doi: 10.1016/j.cub.2010.05.050. Epub 2010 Jun 17.


Relative contributions of chromatin and kinetochores to mitotic spindle assembly.

O'Connell CB, Loncarek J, Kaláb P, Khodjakov A.

J Cell Biol. 2009 Oct 5;187(1):43-51. doi: 10.1083/jcb.200903076.


Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP.

Kohlmaier G, Loncarek J, Meng X, McEwen BF, Mogensen MM, Spektor A, Dynlacht BD, Khodjakov A, Gönczy P.

Curr Biol. 2009 Jun 23;19(12):1012-8. doi: 10.1016/j.cub.2009.05.018. Epub 2009 May 28.


Ab ovo or de novo? Mechanisms of centriole duplication.

Loncarek J, Khodjakov A.

Mol Cells. 2009 Feb 28;27(2):135-42. doi: 10.1007/s10059-009-0017-z. Epub 2009 Feb 20. Review.


The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.

O'Connell CB, Loncarek J, Hergert P, Kourtidis A, Conklin DS, Khodjakov A.

J Cell Biol. 2008 Oct 6;183(1):29-36. doi: 10.1083/jcb.200801038. Epub 2008 Sep 29.


Extra centrosomes and/or chromosomes prolong mitosis in human cells.

Yang Z, Loncarek J, Khodjakov A, Rieder CL.

Nat Cell Biol. 2008 Jun;10(6):748-51. doi: 10.1038/ncb1738. Epub 2008 May 11.


Control of daughter centriole formation by the pericentriolar material.

Loncarek J, Hergert P, Magidson V, Khodjakov A.

Nat Cell Biol. 2008 Mar;10(3):322-8. doi: 10.1038/ncb1694. Epub 2008 Feb 24.


The centromere geometry essential for keeping mitosis error free is controlled by spindle forces.

Loncarek J, Kisurina-Evgenieva O, Vinogradova T, Hergert P, La Terra S, Kapoor TM, Khodjakov A.

Nature. 2007 Nov 29;450(7170):745-9.


Centriole biogenesis: a tale of two pathways.

Loncarek J, Sluder G, Khodjakov A.

Nat Cell Biol. 2007 Jul;9(7):736-8. No abstract available.


Laser microsurgery in the GFP era: a cell biologist's perspective.

Magidson V, Loncarek J, Hergert P, Rieder CL, Khodjakov A.

Methods Cell Biol. 2007;82:239-66. Review.


Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network.

Efimov A, Kharitonov A, Efimova N, Loncarek J, Miller PM, Andreyeva N, Gleeson P, Galjart N, Maia AR, McLeod IX, Yates JR 3rd, Maiato H, Khodjakov A, Akhmanova A, Kaverina I.

Dev Cell. 2007 Jun;12(6):917-30.


Altered cell-cell adhesion in cisplatin-resistant human carcinoma cells: a link between beta-catenin/plakoglobin ratio and cisplatin resistance.

Cimbora-Zovko T, Ambriović-Ristov A, Loncarek J, Osmak M.

Eur J Pharmacol. 2007 Mar 8;558(1-3):27-36. Epub 2006 Dec 12.


Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells.

Uetake Y, Loncarek J, Nordberg JJ, English CN, La Terra S, Khodjakov A, Sluder G.

J Cell Biol. 2007 Jan 15;176(2):173-82.


Influence of p53 status on the HSV-Tk/GCV-induced bystander effect in a panel of human ovarian carcinoma cell lines.

van Dillen IJ, Mulder NH, Sluiter WJ, Meijer C, de Jong S, Loncarek J, Mesnil M, de Vries EF, Vaalburg W, Hospers GA.

Oncol Res. 2005;15(3):151-9.


Consequences of chemoresistance for the herpes simplex virus thymidine kinase/ganciclovir-induced bystander effect in a human small cell lung cancer cell line model.

Van Dillen IJ, Mulder NH, Sluiter WJ, Meijer C, De Jong S, Loncarek J, Mesnil M, De Vries EF, Vaalburg W, Hospers GA.

Anticancer Res. 2005 Jan-Feb;25(1A):255-61.


Catalytically inactive human cathepsin D triggers fibroblast invasive growth.

Laurent-Matha V, Maruani-Herrmann S, Prébois C, Beaujouin M, Glondu M, Noël A, Alvarez-Gonzalez ML, Blacher S, Coopman P, Baghdiguian S, Gilles C, Loncarek J, Freiss G, Vignon F, Liaudet-Coopman E.

J Cell Biol. 2005 Jan 31;168(3):489-99. Epub 2005 Jan 24.


Is the junctional uncoupling elicited in rat ventricular myocytes by some dephosphorylation treatments due to changes in the phosphorylation status of Cx43?

Hervé JC, Plaisance I, Loncarek J, Duthe F, Sarrouilhe D.

Eur Biophys J. 2004 May;33(3):201-10. Epub 2004 Jan 27. Review.


The expression of the tumor suppressor gene connexin 26 is not mediated by methylation in human esophageal cancer cells.

Loncarek J, Yamasaki H, Levillain P, Milinkevitch S, Mesnil M.

Mol Carcinog. 2003 Feb;36(2):74-81.


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