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Items: 1 to 50 of 267

1.

Three-finger toxins from the venom of Micrurus tschudii tschudii (desert coral snake): Isolation and characterization of tschuditoxin-I.

Lomonte B, Camacho E, Fernández J, Salas M, Zavaleta A.

Toxicon. 2019 Jun 15;167:144-151. doi: 10.1016/j.toxicon.2019.06.023. [Epub ahead of print]

PMID:
31211957
2.

New insights into the phylogeographic distribution of the 3FTx/PLA2 venom dichotomy across genus Micrurus in South America.

Sanz L, Quesada-Bernat S, Ramos T, Casais-E-Silva LL, Corrêa-Netto C, Silva-Haad JJ, Sasa M, Lomonte B, Calvete JJ.

J Proteomics. 2019 May 30;200:90-101. doi: 10.1016/j.jprot.2019.03.014. Epub 2019 Apr 1.

PMID:
30946991
3.

Proteomic profiling, functional characterization, and immunoneutralization of the venom of Porthidium porrasi, a pitviper endemic to Costa Rica.

Méndez R, Bonilla F, Sasa M, Dwyer Q, Fernández J, Lomonte B.

Acta Trop. 2019 May;193:113-123. doi: 10.1016/j.actatropica.2019.02.030. Epub 2019 Mar 1.

PMID:
30831113
4.

First look into the venom of Roatan Island's critically endangered coral snake Micrurus ruatanus: Proteomic characterization, toxicity, immunorecognition and neutralization by an antivenom.

Lippa E, Török F, Gómez A, Corrales G, Chacón D, Sasa M, Gutiérrez JM, Lomonte B, Fernández J.

J Proteomics. 2019 Apr 30;198:177-185. doi: 10.1016/j.jprot.2019.01.007. Epub 2019 Jan 17.

PMID:
30659935
5.

Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro.

Rojas-Azofeifa D, Sasa M, Lomonte B, Diego-García E, Ortiz N, Bonilla F, Murillo R, Tytgat J, Díaz C.

Comp Biochem Physiol C Toxicol Pharmacol. 2019 Mar;217:54-67. doi: 10.1016/j.cbpc.2018.11.021. Epub 2018 Dec 2.

PMID:
30517877
6.

Publisher Correction: In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies.

Laustsen AH, Karatt-Vellatt A, Masters EW, Arias AS, Pus U, Knudsen C, Oscoz S, Slavny P, Griffiths DT, Luther AM, Leah RA, Lindholm M, Lomonte B, Gutiérrez JM, McCafferty J.

Nat Commun. 2018 Nov 20;9(1):4957. doi: 10.1038/s41467-018-07480-8.

7.

Neutralizing properties of LY315920 toward snake venom group I and II myotoxic phospholipases A2.

Bryan-Quirós W, Fernández J, Gutiérrez JM, Lewin MR, Lomonte B.

Toxicon. 2019 Jan;157:1-7. doi: 10.1016/j.toxicon.2018.11.292. Epub 2018 Nov 14.

PMID:
30447275
8.

Innovative Immunization Strategies for Antivenom Development.

Bermúdez-Méndez E, Fuglsang-Madsen A, Føns S, Lomonte B, Gutiérrez JM, Laustsen AH.

Toxins (Basel). 2018 Nov 2;10(11). pii: E452. doi: 10.3390/toxins10110452. Review.

9.

In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies.

Laustsen AH, Karatt-Vellatt A, Masters EW, Arias AS, Pus U, Knudsen C, Oscoz S, Slavny P, Griffiths DT, Luther AM, Leah RA, Lindholm M, Lomonte B, Gutiérrez JM, McCafferty J.

Nat Commun. 2018 Oct 2;9(1):3928. doi: 10.1038/s41467-018-06086-4. Erratum in: Nat Commun. 2018 Nov 20;9(1):4957.

10.

Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom.

Lewin MR, Gutiérrez JM, Samuel SP, Herrera M, Bryan-Quirós W, Lomonte B, Bickler PE, Bulfone TC, Williams DJ.

Toxins (Basel). 2018 Sep 20;10(10). pii: E380. doi: 10.3390/toxins10100380.

11.

Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric β-neurotoxin.

Neri-Castro E, Lomonte B, Valdés M, Ponce-López R, Bénard-Valle M, Borja M, Strickland JL, Jones JM, Grünwald C, Zamudio F, Alagón A.

J Proteomics. 2019 Feb 10;192:196-207. doi: 10.1016/j.jprot.2018.09.002. Epub 2018 Sep 8.

PMID:
30205237
12.

Depletion of Complement Enhances the Clearance of Brucella abortus in Mice.

González-Espinoza G, Barquero-Calvo E, Lizano-González E, Alfaro-Alarcón A, Arias-Gómez B, Chaves-Olarte E, Lomonte B, Moreno E, Chacón-Díaz C.

Infect Immun. 2018 Sep 21;86(10). pii: e00567-18. doi: 10.1128/IAI.00567-18. Print 2018 Oct.

13.

Cloning, purification and characterization of nigrelysin, a novel actinoporin from the sea anemone Anthopleura nigrescens.

Alvarado-Mesén J, Solano-Campos F, Canet L, Pedrera L, Hervis YP, Soto C, Borbón H, Lanio ME, Lomonte B, Valle A, Alvarez C.

Biochimie. 2019 Jan;156:206-223. doi: 10.1016/j.biochi.2018.07.013. Epub 2018 Jul 21.

PMID:
30036605
14.

A Snake Venom-Secreted Phospholipase A2 Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis.

Leiguez E, Giannotti KC, Viana MDN, Matsubara MH, Fernandes CM, Gutiérrez JM, Lomonte B, Teixeira C.

Mediators Inflamm. 2018 Jun 14;2018:2547918. doi: 10.1155/2018/2547918. eCollection 2018.

15.

Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity.

Massimino ML, Simonato M, Spolaore B, Franchin C, Arrigoni G, Marin O, Monturiol-Gross L, Fernández J, Lomonte B, Tonello F.

Sci Rep. 2018 Jul 13;8(1):10619. doi: 10.1038/s41598-018-28846-4.

16.

MipLAAO, a new L-amino acid oxidase from the redtail coral snake Micrurus mipartitus.

Rey-Suárez P, Acosta C, Torres U, Saldarriaga-Córdoba M, Lomonte B, Núñez V.

PeerJ. 2018 Jun 8;6:e4924. doi: 10.7717/peerj.4924. eCollection 2018.

17.

A novel pentameric phospholipase A2 myotoxin (PophPLA2) from the venom of the pit viper Porthidium ophryomegas.

Vindas J, Carrera Y, Lomonte B, Gutiérrez JM, Calvete JJ, Sanz L, Fernández J.

Int J Biol Macromol. 2018 Oct 15;118(Pt A):1-8. doi: 10.1016/j.ijbiomac.2018.06.028. Epub 2018 Jun 7.

PMID:
29886171
18.

A myotoxic Lys49 phospholipase A2-homologue is the major component of the venom of Bothrops cotiara from Misiones, Argentina.

de Roodt A, Fernández J, Solano D, Lomonte B.

Toxicon. 2018 Jun 15;148:143-148. doi: 10.1016/j.toxicon.2018.04.026. Epub 2018 Apr 27.

PMID:
29705150
19.

Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms.

Gutiérrez JM, Rucavado A, Escalante T, Herrera C, Fernández J, Lomonte B, Fox JW.

Toxicon. 2018 Jun 15;148:123-131. doi: 10.1016/j.toxicon.2018.04.016. Epub 2018 Apr 23. Review.

PMID:
29698755
20.

Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus.

Sánchez A, Herrera M, Villalta M, Solano D, Segura Á, Lomonte B, Gutiérrez JM, León G, Vargas M.

J Proteomics. 2018 Jun 15;181:104-117. doi: 10.1016/j.jprot.2018.04.007. Epub 2018 Apr 12.

PMID:
29656017
21.

Pros and cons of different therapeutic antibody formats for recombinant antivenom development.

Laustsen AH, María Gutiérrez J, Knudsen C, Johansen KH, Bermúdez-Méndez E, Cerni FA, Jürgensen JA, Ledsgaard L, Martos-Esteban A, Øhlenschlæger M, Pus U, Andersen MR, Lomonte B, Engmark M, Pucca MB.

Toxicon. 2018 May;146:151-175. doi: 10.1016/j.toxicon.2018.03.004. Epub 2018 Mar 10. Review.

22.

Biological and Proteolytic Variation in the Venom of Crotalus scutulatus scutulatus from Mexico.

Borja M, Neri-Castro E, Castañeda-Gaytán G, Strickland JL, Parkinson CL, Castañeda-Gaytán J, Ponce-López R, Lomonte B, Olvera-Rodríguez A, Alagón A, Pérez-Morales R.

Toxins (Basel). 2018 Jan 8;10(1). pii: E35. doi: 10.3390/toxins10010035.

23.

Intravascular hemolysis induced by phospholipases A2 from the venom of the Eastern coral snake, Micrurus fulvius: Functional profiles of hemolytic and non-hemolytic isoforms.

Fernández ML, Quartino PY, Arce-Bejarano R, Fernández J, Camacho LF, Gutiérrez JM, Kuemmel D, Fidelio G, Lomonte B.

Toxicol Lett. 2018 Apr;286:39-47. doi: 10.1016/j.toxlet.2017.11.037. Epub 2017 Nov 29.

PMID:
29197624
24.

High-density peptide microarray exploration of the antibody response in a rabbit immunized with a neurotoxic venom fraction.

Engmark M, Jespersen MC, Lomonte B, Lund O, Laustsen AH.

Toxicon. 2017 Nov;138:151-158. doi: 10.1016/j.toxicon.2017.08.028. Epub 2017 Sep 1.

PMID:
28867663
25.

Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles).

Sáenz A, Ortiz N, Lomonte B, Rucavado A, Díaz C.

Toxicon. 2017 Oct;137:158-167. doi: 10.1016/j.toxicon.2017.08.004. Epub 2017 Aug 5.

PMID:
28789838
26.

Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping.

Engmark M, Lomonte B, Gutiérrez JM, Laustsen AH, De Masi F, Andersen MR, Lund O.

PLoS Negl Trop Dis. 2017 Jul 14;11(7):e0005768. doi: 10.1371/journal.pntd.0005768. eCollection 2017 Jul.

27.

Preclinical Evaluation of the Efficacy of Antivenoms for Snakebite Envenoming: State-of-the-Art and Challenges Ahead.

Gutiérrez JM, Solano G, Pla D, Herrera M, Segura Á, Vargas M, Villalta M, Sánchez A, Sanz L, Lomonte B, León G, Calvete JJ.

Toxins (Basel). 2017 May 13;9(5). pii: E163. doi: 10.3390/toxins9050163. Review.

28.

Protein-species quantitative venomics: looking through a crystal ball.

Calvete JJ, Petras D, Calderón-Celis F, Lomonte B, Encinar JR, Sanz-Medel A.

J Venom Anim Toxins Incl Trop Dis. 2017 Apr 28;23:27. doi: 10.1186/s40409-017-0116-9. eCollection 2017. Review.

29.

Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms.

Lomonte B, Calvete JJ.

J Venom Anim Toxins Incl Trop Dis. 2017 Apr 28;23:26. doi: 10.1186/s40409-017-0117-8. eCollection 2017. Review.

30.

Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom.

Vélez SM, Salazar M, Acosta de Patiño H, Gómez L, Rodriguez A, Correa D, Saldaña J, Navarro D, Lomonte B, Otero-Patiño R, Gutiérrez JM.

Toxicon. 2017 Jun 15;132:55-61. doi: 10.1016/j.toxicon.2017.04.002. Epub 2017 Apr 7.

PMID:
28392273
31.

Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect.

Dias RG, Sampaio SC, Sant'Anna MB, Cunha FQ, Gutiérrez JM, Lomonte B, Cury Y, Picolo G.

J Venom Anim Toxins Incl Trop Dis. 2017 Mar 23;23:18. doi: 10.1186/s40409-017-0104-0. eCollection 2017.

32.

Primary structures and partial toxicological characterization of two phospholipases A2 from Micrurus mipartitus and Micrurus dumerilii coral snake venoms.

Rey-Suárez P, Núñez V, Saldarriaga-Córdoba M, Lomonte B.

Biochimie. 2017 Jun;137:88-98. doi: 10.1016/j.biochi.2017.03.008. Epub 2017 Mar 14.

PMID:
28315380
33.

Exploration of immunoglobulin transcriptomes from mice immunized with three-finger toxins and phospholipases A2 from the Central American coral snake, Micrurus nigrocinctus.

Laustsen AH, Engmark M, Clouser C, Timberlake S, Vigneault F, Gutiérrez JM, Lomonte B.

PeerJ. 2017 Jan 24;5:e2924. doi: 10.7717/peerj.2924. eCollection 2017.

34.

Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".

Salvador GH, Dos Santos JI, Lomonte B, Fontes MR.

Biochimie. 2017 Feb;133:95-102. doi: 10.1016/j.biochi.2016.12.015. Epub 2016 Dec 27.

35.

Pitfalls to avoid when using phage display for snake toxins.

Laustsen AH, Lauridsen LP, Lomonte B, Andersen MR, Lohse B.

Toxicon. 2017 Feb;126:79-89. doi: 10.1016/j.toxicon.2016.12.010. Epub 2016 Dec 23.

PMID:
28017694
36.

High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays.

Engmark M, Andersen MR, Laustsen AH, Patel J, Sullivan E, de Masi F, Hansen CS, Kringelum JV, Lomonte B, Gutiérrez JM, Lund O.

Sci Rep. 2016 Nov 8;6:36629. doi: 10.1038/srep36629.

37.

Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis).

Pla D, Sanz L, Sasa M, Acevedo ME, Dwyer Q, Durban J, Pérez A, Rodriguez Y, Lomonte B, Calvete JJ.

J Proteomics. 2017 Jan 30;152:1-12. doi: 10.1016/j.jprot.2016.10.006. Epub 2016 Oct 21.

PMID:
27777178
38.

Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.

Lomonte B, Rey-Suárez P, Fernández J, Sasa M, Pla D, Vargas N, Bénard-Valle M, Sanz L, Corrêa-Netto C, Núñez V, Alape-Girón A, Alagón A, Gutiérrez JM, Calvete JJ.

Toxicon. 2016 Nov;122:7-25. doi: 10.1016/j.toxicon.2016.09.008. Epub 2016 Sep 15. Review.

PMID:
27641749
39.

Exploring the venom of the forest cobra snake: Toxicovenomics and antivenom profiling of Naja melanoleuca.

Lauridsen LP, Laustsen AH, Lomonte B, Gutiérrez JM.

J Proteomics. 2017 Jan 6;150:98-108. doi: 10.1016/j.jprot.2016.08.024. Epub 2016 Sep 1.

PMID:
27593527
40.

Novel Catalytically-Inactive PII Metalloproteinases from a Viperid Snake Venom with Substitutions in the Canonical Zinc-Binding Motif.

Camacho E, Sanz L, Escalante T, Pérez A, Villalta F, Lomonte B, Neves-Ferreira AG, Feoli A, Calvete JJ, Gutiérrez JM, Rucavado A.

Toxins (Basel). 2016 Oct 12;8(10). pii: E292.

41.

Divergent functional profiles of acidic and basic phospholipases A2 in the venom of the snake Porthidium lansbergii lansbergii.

Jiménez-Charris E, Montealegre-Sánchez L, Solano-Redondo L, Castro-Herrera F, Fierro-Pérez L, Lomonte B.

Toxicon. 2016 Sep 1;119:289-98. doi: 10.1016/j.toxicon.2016.07.006. Epub 2016 Jul 2.

PMID:
27381371
42.

From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy.

Laustsen AH, Engmark M, Milbo C, Johannesen J, Lomonte B, Gutiérrez JM, Lohse B.

Curr Pharm Des. 2016;22(34):5270-5293. Review.

PMID:
27339430
43.

Venomic Analysis of the Poorly Studied Desert Coral Snake, Micrurus tschudii tschudii, Supports the 3FTx/PLA₂ Dichotomy across Micrurus Venoms.

Sanz L, Pla D, Pérez A, Rodríguez Y, Zavaleta A, Salas M, Lomonte B, Calvete JJ.

Toxins (Basel). 2016 Jun 7;8(6). pii: E178. doi: 10.3390/toxins8060178.

44.

Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2.

Casais-E-Silva LL, Teixeira CF, Lebrun I, Lomonte B, Alape-Girón A, Gutiérrez JM.

Toxicol Lett. 2016 Aug 22;257:60-71. doi: 10.1016/j.toxlet.2016.06.005. Epub 2016 Jun 7.

PMID:
27282409
45.

Screening for target toxins of the antiophidic protein DM64 through a gel-based interactomics approach.

Rocha SL, Neves-Ferreira AG, Trugilho MR, Angulo Y, Lomonte B, Valente RH, Domont GB, Perales J.

J Proteomics. 2017 Jan 16;151:204-213. doi: 10.1016/j.jprot.2016.05.020. Epub 2016 May 20.

PMID:
27216643
46.

Venom of the Coral Snake Micrurus clarki: Proteomic Profile, Toxicity, Immunological Cross-Neutralization, and Characterization of a Three-Finger Toxin.

Lomonte B, Sasa M, Rey-Suárez P, Bryan W, Gutiérrez JM.

Toxins (Basel). 2016 May 5;8(5). pii: E138. doi: 10.3390/toxins8050138.

47.

Corrigendum: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin.

Smith AI, Rajapakse NW, Kleifeld O, Lomonte B, Sikanyika NL, Spicer AJ, Hodgson WC, Conroy PJ, Small DH, Kaye DM, Parkington HC, Whisstock JC, Kuruppu S.

Sci Rep. 2016 Apr 22;6:24333. doi: 10.1038/srep24333. No abstract available.

48.

N-Formyl-Perosamine Surface Homopolysaccharides Hinder the Recognition of Brucella abortus by Mouse Neutrophils.

Mora-Cartín R, Chacón-Díaz C, Gutiérrez-Jiménez C, Gurdián-Murillo S, Lomonte B, Chaves-Olarte E, Barquero-Calvo E, Moreno E.

Infect Immun. 2016 May 24;84(6):1712-21. doi: 10.1128/IAI.00137-16. Print 2016 Jun.

49.

Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii.

Fernández J, Gutiérrez JM, Calvete JJ, Sanz L, Lomonte B.

Biochimie. 2016 Jun;125:83-90. doi: 10.1016/j.biochi.2016.03.004. Epub 2016 Mar 10.

PMID:
26973135
50.

N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin.

Smith AI, Rajapakse NW, Kleifeld O, Lomonte B, Sikanyika NL, Spicer AJ, Hodgson WC, Conroy PJ, Small DH, Kaye DM, Parkington HC, Whisstock JC, Kuruppu S.

Sci Rep. 2016 Mar 2;6:22413. doi: 10.1038/srep22413. Erratum in: Sci Rep. 2016 Apr 22;6:24333.

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