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Items: 1 to 50 of 159

1.

Improving plant transient expression through the rational design of synthetic 5' and 3' untranslated regions.

Peyret H, Brown JKM, Lomonossoff GP.

Plant Methods. 2019 Sep 18;15:108. doi: 10.1186/s13007-019-0494-9. eCollection 2019.

2.

Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice.

Fay PC, Attoui H, Batten C, Mohd Jaafar F, Lomonossoff GP, Daly JM, Mertens PPC.

Vaccine X. 2019 Jun 22;2:100026. doi: 10.1016/j.jvacx.2019.100026. eCollection 2019 Aug 9.

3.

Plant-Made Nervous Necrosis Virus-Like Particles Protect Fish Against Disease.

Marsian J, Hurdiss DL, Ranson NA, Ritala A, Paley R, Cano I, Lomonossoff GP.

Front Plant Sci. 2019 Jul 9;10:880. doi: 10.3389/fpls.2019.00880. eCollection 2019.

4.

Amino acids at the exposed C-terminus of the S coat protein of cowpea mosaic virus play different roles in particle formation and viral systemic movement.

Meshcheriakova Y, Lomonossoff GP.

J Gen Virol. 2019 Jul;100(7):1165-1170. doi: 10.1099/jgv.0.001285. Epub 2019 Jun 6.

PMID:
31169482
5.

Affimer reagents as tools in diagnosing plant virus diseases.

Hesketh EL, Tiede C, Adamson H, Adams TL, Byrne MJ, Meshcheriakova Y, Kruse I, McPherson MJ, Lomonossoff GP, Tomlinson DC, Ranson NA.

Sci Rep. 2019 May 17;9(1):7524. doi: 10.1038/s41598-019-43945-6.

6.

Epitope Presentation of Dengue Viral Envelope Glycoprotein Domain III on Hepatitis B Core Protein Virus-Like Particles Produced in Nicotiana benthamiana.

Pang EL, Peyret H, Ramirez A, Loh HS, Lai KS, Fang CM, Rosenberg WM, Lomonossoff GP.

Front Plant Sci. 2019 Apr 16;10:455. doi: 10.3389/fpls.2019.00455. eCollection 2019.

7.

Investigating the Biological Relevance of In Vitro-Identified Putative Packaging Signals at the 5' Terminus of Satellite Tobacco Necrosis Virus 1 Genomic RNA.

Kotta-Loizou I, Peyret H, Saunders K, Coutts RHA, Lomonossoff GP.

J Virol. 2019 Apr 17;93(9). pii: e02106-18. doi: 10.1128/JVI.02106-18. Print 2019 May 1.

8.

Viral nanoparticles can elude protein barriers: exploiting rather than imitating nature.

Berardi A, Baldelli Bombelli F, Thuenemann EC, Lomonossoff GP.

Nanoscale. 2019 Jan 31;11(5):2306-2316. doi: 10.1039/c8nr09067j.

PMID:
30662985
9.

Encapsidation of Viral RNA in Picornavirales: Studies on Cowpea Mosaic Virus Demonstrate Dependence on Viral Replication.

Kruse I, Peyret H, Saxena P, Lomonossoff GP.

J Virol. 2019 Jan 4;93(2). pii: e01520-18. doi: 10.1128/JVI.01520-18. Print 2019 Jan 15.

10.

TMV Particles: The Journey From Fundamental Studies to Bionanotechnology Applications.

Lomonossoff GP, Wege C.

Adv Virus Res. 2018;102:149-176. doi: 10.1016/bs.aivir.2018.06.003. Epub 2018 Jul 26. Review.

PMID:
30266172
11.

The 3.3 Å structure of a plant geminivirus using cryo-EM.

Hesketh EL, Saunders K, Fisher C, Potze J, Stanley J, Lomonossoff GP, Ranson NA.

Nat Commun. 2018 Jun 18;9(1):2369. doi: 10.1038/s41467-018-04793-6.

12.

Delivering Cargo: Plant-Based Production of Bluetongue Virus Core-Like and Virus-Like Particles Containing Fluorescent Proteins.

Thuenemann EC, Lomonossoff GP.

Methods Mol Biol. 2018;1776:319-334. doi: 10.1007/978-1-4939-7808-3_22.

PMID:
29869252
13.

Production of Mosaic Turnip Crinkle Virus-Like Particles Derived by Coinfiltration of Wild-Type and Modified Forms of Virus Coat Protein in Plants.

Castells-Graells R, Lomonossoff GP, Saunders K.

Methods Mol Biol. 2018;1776:3-17. doi: 10.1007/978-1-4939-7808-3_1.

PMID:
29869231
14.

So What Have Plant Viruses Ever Done for Virology and Molecular Biology?

Lomonossoff GP.

Adv Virus Res. 2018;100:145-162. doi: 10.1016/bs.aivir.2017.12.001. Epub 2018 Feb 1. Review.

PMID:
29551134
15.

Stability of plant virus-based nanocarriers in gastrointestinal fluids.

Berardi A, Evans DJ, Baldelli Bombelli F, Lomonossoff GP.

Nanoscale. 2018 Jan 25;10(4):1667-1679. doi: 10.1039/c7nr07182e.

16.

Combining high-resolution cryo-electron microscopy and mutagenesis to develop cowpea mosaic virus for bionanotechnology.

Meshcheriakova Y, Durrant A, Hesketh EL, Ranson NA, Lomonossoff GP.

Biochem Soc Trans. 2017 Dec 15;45(6):1263-1269. doi: 10.1042/BST20160312. Epub 2017 Nov 3. Review.

17.

In Planta Synthesis of Designer-Length Tobacco Mosaic Virus-Based Nano-Rods That Can Be Used to Fabricate Nano-Wires.

Saunders K, Lomonossoff GP.

Front Plant Sci. 2017 Aug 18;8:1335. doi: 10.3389/fpls.2017.01335. eCollection 2017.

18.

Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine.

Marsian J, Fox H, Bahar MW, Kotecha A, Fry EE, Stuart DI, Macadam AJ, Rowlands DJ, Lomonossoff GP.

Nat Commun. 2017 Aug 15;8(1):245. doi: 10.1038/s41467-017-00090-w.

19.

Detection of Serum Antibodies to Hepatitis E Virus Based on HEV Genotype 3 ORF2 Capsid Protein Expressed in Nicotiana benthamiana.

Mazalovska M, Varadinov N, Koynarski T, Minkov I, Teoharov P, Lomonossoff GP, Zahmanova G.

Ann Lab Med. 2017 Jul;37(4):313-319. doi: 10.3343/alm.2017.37.4.313.

20.

The structures of a naturally empty cowpea mosaic virus particle and its genome-containing counterpart by cryo-electron microscopy.

Hesketh EL, Meshcheriakova Y, Thompson RF, Lomonossoff GP, Ranson NA.

Sci Rep. 2017 Apr 3;7(1):539. doi: 10.1038/s41598-017-00533-w.

21.

Efficient Transient Expression of Recombinant Proteins in Plants by the Novel pEff Vector Based on the Genome of Potato Virus X.

Mardanova ES, Blokhina EA, Tsybalova LM, Peyret H, Lomonossoff GP, Ravin NV.

Front Plant Sci. 2017 Feb 28;8:247. doi: 10.3389/fpls.2017.00247. eCollection 2017.

22.

Plant-expressed Hepatitis B core antigen virus-like particles: Characterization and investigation of their stability in simulated and pig gastro-intestinal fluids.

Berardi A, Lomonossoff GP, Evans DJ, Barker SA.

Int J Pharm. 2017 Apr 30;522(1-2):147-156. doi: 10.1016/j.ijpharm.2017.03.001. Epub 2017 Mar 2.

PMID:
28263835
23.

Engineering Recombinant Virus-like Nanoparticles from Plants for Cellular Delivery.

Brillault L, Jutras PV, Dashti N, Thuenemann EC, Morgan G, Lomonossoff GP, Landsberg MJ, Sainsbury F.

ACS Nano. 2017 Apr 25;11(4):3476-3484. doi: 10.1021/acsnano.6b07747. Epub 2017 Feb 15.

PMID:
28198180
24.

Synthetic plant virology for nanobiotechnology and nanomedicine.

Steele JFC, Peyret H, Saunders K, Castells-Graells R, Marsian J, Meshcheriakova Y, Lomonossoff GP.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jul;9(4). doi: 10.1002/wnan.1447. Epub 2017 Jan 11. Review.

25.

Plant-produced biopharmaceuticals: A case of technical developments driving clinical deployment.

Lomonossoff GP, D'Aoust MA.

Science. 2016 Sep 16;353(6305):1237-40. doi: 10.1126/science.aaf6638. Review.

PMID:
27634524
26.

Crystal Structure and Proteomics Analysis of Empty Virus-like Particles of Cowpea Mosaic Virus.

Huynh NT, Hesketh EL, Saxena P, Meshcheriakova Y, Ku YC, Hoang LT, Johnson JE, Ranson NA, Lomonossoff GP, Reddy VS.

Structure. 2016 Apr 5;24(4):567-575. doi: 10.1016/j.str.2016.02.011. Epub 2016 Mar 24.

27.

Molecular pharming - VLPs made in plants.

Marsian J, Lomonossoff GP.

Curr Opin Biotechnol. 2016 Feb;37:201-206. doi: 10.1016/j.copbio.2015.12.007. Epub 2016 Jan 14. Review.

28.

The Generation of Turnip Crinkle Virus-Like Particles in Plants by the Transient Expression of Wild-Type and Modified Forms of Its Coat Protein.

Saunders K, Lomonossoff GP.

Front Plant Sci. 2015 Dec 24;6:1138. doi: 10.3389/fpls.2015.01138. eCollection 2015.

29.

High immunogenicity of plant-produced candidate influenza vaccine based on the M2e peptide fused to flagellin.

Mardanova ES, Kotlyarov RY, Kuprianov VV, Stepanova LA, Tsybalova LM, Lomonossoff GP, Ravin NV.

Bioengineered. 2016;7(1):28-32. doi: 10.1080/21655979.2015.1126017. Epub 2015 Dec 28.

30.

Mechanisms of assembly and genome packaging in an RNA virus revealed by high-resolution cryo-EM.

Hesketh EL, Meshcheriakova Y, Dent KC, Saxena P, Thompson RF, Cockburn JJ, Lomonossoff GP, Ranson NA.

Nat Commun. 2015 Dec 10;6:10113. doi: 10.1038/ncomms10113.

31.

Virus-Derived Vectors for the Expression of Multiple Proteins in Plants.

Saxena P, Thuenemann EC, Sainsbury F, Lomonossoff GP.

Methods Mol Biol. 2016;1385:39-54. doi: 10.1007/978-1-4939-3289-4_3.

PMID:
26614280
32.

A virus-based nanoplasmonic structure as a surface-enhanced Raman biosensor.

Lebedev N, Griva I, Dressick WJ, Phelps J, Johnson JE, Meshcheriakova Y, Lomonossoff GP, Soto CM.

Biosens Bioelectron. 2016 Mar 15;77:306-14. doi: 10.1016/j.bios.2015.09.032. Epub 2015 Sep 21. Erratum in: Biosens Bioelectron. 2016 May 15;79:947.

33.

When plant virology met Agrobacterium: the rise of the deconstructed clones.

Peyret H, Lomonossoff GP.

Plant Biotechnol J. 2015 Oct;13(8):1121-35. doi: 10.1111/pbi.12412. Epub 2015 Jun 12. Review.

34.

Development of a non-infectious encapsidated positive control RNA for molecular assays to detect foot-and-mouth disease virus.

Madi M, Mioulet V, King DP, Lomonossoff GP, Montague NP.

J Virol Methods. 2015 Aug;220:27-34. doi: 10.1016/j.jviromet.2015.04.002. Epub 2015 Apr 9.

35.

Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins.

Peyret H, Gehin A, Thuenemann EC, Blond D, El Turabi A, Beales L, Clarke D, Gilbert RJ, Fry EE, Stuart DI, Holmes K, Stonehouse NJ, Whelan M, Rosenberg W, Lomonossoff GP, Rowlands DJ.

PLoS One. 2015 Apr 1;10(4):e0120751. doi: 10.1371/journal.pone.0120751. eCollection 2015.

36.

Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody.

Jobsri J, Allen A, Rajagopal D, Shipton M, Kanyuka K, Lomonossoff GP, Ottensmeier C, Diebold SS, Stevenson FK, Savelyeva N.

PLoS One. 2015 Feb 18;10(2):e0118096. doi: 10.1371/journal.pone.0118096. eCollection 2015.

37.

Revealing the density of encoded functions in a viral RNA.

Patel N, Dykeman EC, Coutts RH, Lomonossoff GP, Rowlands DJ, Phillips SE, Ranson N, Twarock R, Tuma R, Stockley PG.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2227-32. doi: 10.1073/pnas.1420812112. Epub 2015 Feb 2.

38.

Structural insights into magnetic clusters grown inside virus capsids.

Jaafar M, Aljabali AA, Berlanga I, Mas-Ballesté R, Saxena P, Warren S, Lomonossoff GP, Evans DJ, de Pablo PJ.

ACS Appl Mater Interfaces. 2014 Dec 10;6(23):20936-42. doi: 10.1021/am505682x. Epub 2014 Nov 26.

PMID:
25405995
39.

Virus infection cycle events coupled to RNA replication.

Saxena P, Lomonossoff GP.

Annu Rev Phytopathol. 2014;52:197-212. doi: 10.1146/annurev-phyto-102313-050205. Epub 2014 May 30. Review.

PMID:
24906127
40.

Transient expressions of synthetic biology in plants.

Sainsbury F, Lomonossoff GP.

Curr Opin Plant Biol. 2014 Jun;19:1-7. doi: 10.1016/j.pbi.2014.02.003. Epub 2014 Mar 12.

41.

Fine-tuning levels of heterologous gene expression in plants by orthogonal variation of the untranslated regions of a nonreplicating transient expression system.

Meshcheriakova YA, Saxena P, Lomonossoff GP.

Plant Biotechnol J. 2014 Aug;12(6):718-27. doi: 10.1111/pbi.12175. Epub 2014 Mar 12.

42.

Genetic engineering and characterization of Cowpea mosaic virus empty virus-like particles.

Sainsbury F, Saxena P, Aljabali AA, Saunders K, Evans DJ, Lomonossoff GP.

Methods Mol Biol. 2014;1108:139-53. doi: 10.1007/978-1-62703-751-8_11.

PMID:
24243247
43.

Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants.

Geisler K, Hughes RK, Sainsbury F, Lomonossoff GP, Rejzek M, Fairhurst S, Olsen CE, Motawia MS, Melton RE, Hemmings AM, Bak S, Osbourn A.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):E3360-7. doi: 10.1073/pnas.1309157110. Epub 2013 Aug 12.

44.

Structure-based design and experimental engineering of a plant virus nanoparticle for the presentation of immunogenic epitopes and as a drug carrier.

Arcangeli C, Circelli P, Donini M, Aljabali AA, Benvenuto E, Lomonossoff GP, Marusic C.

J Biomol Struct Dyn. 2014 Apr;32(4):630-47. doi: 10.1080/07391102.2013.785920. Epub 2013 May 15.

PMID:
23672348
45.

A method for rapid production of heteromultimeric protein complexes in plants: assembly of protective bluetongue virus-like particles.

Thuenemann EC, Meyers AE, Verwey J, Rybicki EP, Lomonossoff GP.

Plant Biotechnol J. 2013 Sep;11(7):839-46. doi: 10.1111/pbi.12076. Epub 2013 May 6.

46.

Modularity of plant metabolic gene clusters: a trio of linked genes that are collectively required for acylation of triterpenes in oat.

Mugford ST, Louveau T, Melton R, Qi X, Bakht S, Hill L, Tsurushima T, Honkanen S, Rosser SJ, Lomonossoff GP, Osbourn A.

Plant Cell. 2013 Mar;25(3):1078-92. doi: 10.1105/tpc.113.110551. Epub 2013 Mar 26. Erratum in: Plant Cell. 2013 Sep;25(9):3632.

47.

The pEAQ vector series: the easy and quick way to produce recombinant proteins in plants.

Peyret H, Lomonossoff GP.

Plant Mol Biol. 2013 Sep;83(1-2):51-8. doi: 10.1007/s11103-013-0036-1. Epub 2013 Mar 12. Review.

PMID:
23479085
48.

Exploiting plant virus-derived components to achieve in planta expression and for templates for synthetic biology applications.

Saunders K, Lomonossoff GP.

New Phytol. 2013 Oct;200(1):16-26. doi: 10.1111/nph.12204. Epub 2013 Mar 4. Review.

49.

The use of transient expression systems for the rapid production of virus-like particles in plants.

Thuenemann EC, Lenzi P, Love AJ, Taliansky M, Bécares M, Zuñiga S, Enjuanes L, Zahmanova GG, Minkov IN, Matić S, Noris E, Meyers A, Hattingh A, Rybicki EP, Kiselev OI, Ravin NV, Eldarov MA, Skryabin KG, Lomonossoff GP.

Curr Pharm Des. 2013;19(31):5564-73. Review.

PMID:
23394559
50.

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity.

Porta C, Xu X, Loureiro S, Paramasivam S, Ren J, Al-Khalil T, Burman A, Jackson T, Belsham GJ, Curry S, Lomonossoff GP, Parida S, Paton D, Li Y, Wilsden G, Ferris N, Owens R, Kotecha A, Fry E, Stuart DI, Charleston B, Jones IM.

J Virol Methods. 2013 Feb;187(2):406-12. doi: 10.1016/j.jviromet.2012.11.011. Epub 2012 Nov 19.

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