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Items: 1 to 50 of 61

1.

Emerging Genetic and Epigenetic Mechanisms Underlying Pubertal Maturation in Adolescence.

Aylwin CF, Toro CA, Shirtcliff E, Lomniczi A.

J Res Adolesc. 2019 Mar;29(1):54-79. doi: 10.1111/jora.12385.

PMID:
30869843
2.

The Emerging Role of Chromatin Remodeling Factors in Female Pubertal Development.

Aylwin CF, Vigh-Conrad K, Lomniczi A.

Neuroendocrinology. 2019 Feb 7. doi: 10.1159/000497745. [Epub ahead of print] Review.

3.

Modulation of Gpr39, a G-protein coupled receptor associated with alcohol use in non-human primates, curbs ethanol intake in mice.

Cuzon Carlson VC, Ford MM, Carlson TL, Lomniczi A, Grant KA, Ferguson B, Cervera-Juanes RP.

Neuropsychopharmacology. 2019 May;44(6):1103-1113. doi: 10.1038/s41386-018-0308-1. Epub 2019 Jan 5.

PMID:
30610192
4.

EAP1 regulation of GnRH promoter activity is important for human pubertal timing.

Mancini A, Howard SR, Cabrera CP, Barnes MR, David A, Wehkalampi K, Heger S, Lomniczi A, Guasti L, Ojeda SR, Dunkel L.

Hum Mol Genet. 2019 Apr 15;28(8):1357-1368. doi: 10.1093/hmg/ddy451.

5.

Methylome profiling of healthy and central precocious puberty girls.

Bessa DS, Maschietto M, Aylwin CF, Canton APM, Brito VN, Macedo DB, Cunha-Silva M, Palhares HMC, de Resende EAMR, Borges MF, Mendonca BB, Netchine I, Krepischi ACV, Lomniczi A, Ojeda SR, Latronico AC.

Clin Epigenetics. 2018 Nov 22;10(1):146. doi: 10.1186/s13148-018-0581-1.

6.

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression.

Vazquez MJ, Toro CA, Castellano JM, Ruiz-Pino F, Roa J, Beiroa D, Heras V, Velasco I, Dieguez C, Pinilla L, Gaytan F, Nogueiras R, Bosch MA, Rønnekleiv OK, Lomniczi A, Ojeda SR, Tena-Sempere M.

Nat Commun. 2018 Oct 10;9(1):4194. doi: 10.1038/s41467-018-06459-9.

7.

Elucidating the genetic architecture of reproductive ageing in the Japanese population.

Horikoshi M, Day FR, Akiyama M, Hirata M, Kamatani Y, Matsuda K, Ishigaki K, Kanai M, Wright H, Toro CA, Ojeda SR, Lomniczi A, Kubo M, Ong KK, Perry JRB.

Nat Commun. 2018 May 17;9(1):1977. doi: 10.1038/s41467-018-04398-z.

8.

Hypothalamic epigenetics driving female puberty.

Toro CA, Aylwin CF, Lomniczi A.

J Neuroendocrinol. 2018 Jul;30(7):e12589. doi: 10.1111/jne.12589. Review.

PMID:
29520866
9.

Trithorax dependent changes in chromatin landscape at enhancer and promoter regions drive female puberty.

Toro CA, Wright H, Aylwin CF, Ojeda SR, Lomniczi A.

Nat Commun. 2018 Jan 4;9(1):57. doi: 10.1038/s41467-017-02512-1.

10.

Changes in the expression of genes involved in the ovarian function of rats caused by daily exposure to 3-methylcholanthrene and their prevention by α-naphthoflavone.

Rhon-Calderón EA, Toro CA, Lomniczi A, Galarza RA, Faletti AG.

Arch Toxicol. 2018 Feb;92(2):907-919. doi: 10.1007/s00204-017-2096-5. Epub 2017 Nov 1.

11.

Engineering a gene silencing viral construct that targets the cat hypothalamus to induce permanent sterility: An update.

Dissen GA, Adachi K, Lomniczi A, Chatkupt T, Davidson BL, Nakai H, Ojeda SR.

Reprod Domest Anim. 2017 Apr;52 Suppl 2:354-358. doi: 10.1111/rda.12834. Epub 2016 Nov 17.

12.

The systemic and gonadal toxicity of 3-methylcholanthrene is prevented by daily administration of α-naphthoflavone.

Rhon-Calderón EA, Galarza RA, Lomniczi A, Faletti AG.

Toxicology. 2016 Apr 15;353-354:58-69. doi: 10.1016/j.tox.2016.05.005. Epub 2016 May 6.

PMID:
27163632
13.

The Emerging Role of Epigenetics in the Regulation of Female Puberty.

Lomniczi A, Ojeda SR.

Endocr Dev. 2016;29:1-16. doi: 10.1159/000438840. Epub 2015 Dec 17. Review.

14.

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression.

Lomniczi A, Wright H, Castellano JM, Matagne V, Toro CA, Ramaswamy S, Plant TM, Ojeda SR.

Nat Commun. 2015 Dec 16;6:10195. doi: 10.1038/ncomms10195.

15.

Epigenetic regulation of female puberty.

Lomniczi A, Wright H, Ojeda SR.

Front Neuroendocrinol. 2015 Jan;36:90-107. doi: 10.1016/j.yfrne.2014.08.003. Epub 2014 Aug 27. Review.

PMID:
25171849
16.

Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome.

Topaloglu AK, Lomniczi A, Kretzschmar D, Dissen GA, Kotan LD, McArdle CA, Koc AF, Hamel BC, Guclu M, Papatya ED, Eren E, Mengen E, Gurbuz F, Cook M, Castellano JM, Kekil MB, Mungan NO, Yuksel B, Ojeda SR.

J Clin Endocrinol Metab. 2014 Oct;99(10):E2067-75. doi: 10.1210/jc.2014-1836. Epub 2014 Jul 17.

17.

Loss of Ntrk2/Kiss1r signaling in oocytes causes premature ovarian failure.

Dorfman MD, Garcia-Rudaz C, Alderman Z, Kerr B, Lomniczi A, Dissen GA, Castellano JM, Garcia-Galiano D, Gaytan F, Xu B, Tena-Sempere M, Ojeda SR.

Endocrinology. 2014 Aug;155(8):3098-111. doi: 10.1210/en.2014-1111. Epub 2014 May 30.

18.

An alternative transcription start site yields estrogen-unresponsive Kiss1 mRNA transcripts in the hypothalamus of prepubertal female rats.

Castellano JM, Wright H, Ojeda SR, Lomniczi A.

Neuroendocrinology. 2014;99(2):94-107. doi: 10.1159/000362280. Epub 2014 Mar 28.

19.

Puberty in 2013: Unravelling the mystery of puberty.

Ojeda SR, Lomniczi A.

Nat Rev Endocrinol. 2014 Feb;10(2):67-9. doi: 10.1038/nrendo.2013.233. Epub 2013 Nov 26. Review.

PMID:
24275741
20.

A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates.

Lomniczi A, Wright H, Castellano JM, Sonmez K, Ojeda SR.

Horm Behav. 2013 Jul;64(2):175-86. doi: 10.1016/j.yhbeh.2012.09.013. Review.

21.

Applying gene silencing technology to contraception.

Dissen GA, Lomniczi A, Boudreau RL, Chen YH, Davidson BL, Ojeda SR.

Reprod Domest Anim. 2012 Dec;47 Suppl 6:381-6. doi: 10.1111/rda.12016.

22.

Epigenetic control of female puberty.

Lomniczi A, Loche A, Castellano JM, Ronnekleiv OK, Bosch M, Kaidar G, Knoll JG, Wright H, Pfeifer GP, Ojeda SR.

Nat Neurosci. 2013 Mar;16(3):281-9. doi: 10.1038/nn.3319. Epub 2013 Jan 27.

23.

Targeted gene silencing to induce permanent sterility.

Dissen GA, Lomniczi A, Boudreau RL, Chen YH, Davidson BL, Ojeda SR.

Reprod Domest Anim. 2012 Aug;47 Suppl 4:228-32. doi: 10.1111/j.1439-0531.2012.02080.x.

24.

Transcription of the human EAP1 gene is regulated by upstream components of a puberty-controlling Tumor Suppressor Gene network.

Mueller JK, Koch I, Lomniczi A, Loche A, Rulfs T, Castellano JM, Kiess W, Ojeda S, Heger S.

Mol Cell Endocrinol. 2012 Apr 4;351(2):184-98. doi: 10.1016/j.mce.2011.12.004. Epub 2011 Dec 19.

25.

Hypothalamic EAP1 (enhanced at puberty 1) is required for menstrual cyclicity in nonhuman primates.

Dissen GA, Lomniczi A, Heger S, Neff TL, Ojeda SR.

Endocrinology. 2012 Jan;153(1):350-61. doi: 10.1210/en.2011-1541. Epub 2011 Nov 29.

26.

A single-nucleotide polymorphism in the EAP1 gene is associated with amenorrhea/oligomenorrhea in nonhuman primates.

Lomniczi A, Garcia-Rudaz C, Ramakrishnan R, Wilmot B, Khouangsathiene S, Ferguson B, Dissen GA, Ojeda SR.

Endocrinology. 2012 Jan;153(1):339-49. doi: 10.1210/en.2011-1540. Epub 2011 Nov 29.

27.

Transcriptional regulation of the human KiSS1 gene.

Mueller JK, Dietzel A, Lomniczi A, Loche A, Tefs K, Kiess W, Danne T, Ojeda SR, Heger S.

Mol Cell Endocrinol. 2011 Aug 6;342(1-2):8-19. doi: 10.1016/j.mce.2011.04.025. Epub 2011 Jun 6.

28.

A novel transcription complex that selectively modulates apoptosis of breast cancer cells through regulation of FASTKD2.

Yeung KT, Das S, Zhang J, Lomniczi A, Ojeda SR, Xu CF, Neubert TA, Samuels HH.

Mol Cell Biol. 2011 Jun;31(11):2287-98. doi: 10.1128/MCB.01381-10. Epub 2011 Mar 28.

29.

Contribution of glial-neuronal interactions to the neuroendocrine control of female puberty.

Ojeda SR, Lomniczi A, Sandau U.

Eur J Neurosci. 2010 Dec;32(12):2003-10. doi: 10.1111/j.1460-9568.2010.07515.x. Review.

30.

The transcriptional control of female puberty.

Ojeda SR, Lomniczi A, Loche A, Matagne V, Kaidar G, Sandau US, Dissen GA.

Brain Res. 2010 Dec 10;1364:164-74. doi: 10.1016/j.brainres.2010.09.039. Epub 2010 Sep 17. Review.

31.

Gene networks and the neuroendocrine regulation of puberty.

Ojeda SR, Dubay C, Lomniczi A, Kaidar G, Matagne V, Sandau US, Dissen GA.

Mol Cell Endocrinol. 2010 Aug 5;324(1-2):3-11. doi: 10.1016/j.mce.2009.12.003. Epub 2009 Dec 22.

32.

New concepts on the control of the onset of puberty.

Ojeda SR, Lomniczi A, Sandau U, Matagne V.

Endocr Dev. 2010;17:44-51. doi: 10.1159/000262527. Epub 2009 Nov 24. Review.

PMID:
19955755
33.

In vivo manipulation of gene expression in non-human primates using lentiviral vectors as delivery vehicles.

Dissen GA, Lomniczi A, Neff TL, Hobbs TR, Kohama SG, Kroenke CD, Galimi F, Ojeda SR.

Methods. 2009 Sep;49(1):70-7. doi: 10.1016/j.ymeth.2009.06.004. Epub 2009 Jun 24. Review.

34.

Glial-gonadotrophin hormone (GnRH) neurone interactions in the median eminence and the control of GnRH secretion.

Ojeda SR, Lomniczi A, Sandau US.

J Neuroendocrinol. 2008 Jun;20(6):732-42. doi: 10.1111/j.1365-2826.2008.01712.x. Review.

PMID:
18601696
35.

Oxytocin facilitates female sexual maturation through a glia-to-neuron signaling pathway.

Parent AS, Rasier G, Matagne V, Lomniczi A, Lebrethon MC, Gérard A, Ojeda SR, Bourguignon JP.

Endocrinology. 2008 Mar;149(3):1358-65. Epub 2007 Nov 26.

36.

A contactin-receptor-like protein tyrosine phosphatase beta complex mediates adhesive communication between astroglial cells and gonadotrophin-releasing hormone neurones.

Parent AS, Mungenast AE, Lomniczi A, Sandau US, Peles E, Bosch MA, Rønnekleiv OK, Ojeda SR.

J Neuroendocrinol. 2007 Nov;19(11):847-59.

37.

Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis.

Heger S, Mastronardi C, Dissen GA, Lomniczi A, Cabrera R, Roth CL, Jung H, Galimi F, Sippell W, Ojeda SR.

J Clin Invest. 2007 Aug;117(8):2145-54.

38.

Expression of a tumor-related gene network increases in the mammalian hypothalamus at the time of female puberty.

Roth CL, Mastronardi C, Lomniczi A, Wright H, Cabrera R, Mungenast AE, Heger S, Jung H, Dubay C, Ojeda SR.

Endocrinology. 2007 Nov;148(11):5147-61. Epub 2007 Jul 5.

PMID:
17615149
39.

Quantitative proteomics identifies a change in glial glutamate metabolism at the time of female puberty.

Roth CL, McCormack AL, Lomniczi A, Mungenast AE, Ojeda SR.

Mol Cell Endocrinol. 2006 Jul 25;254-255:51-9. Epub 2006 Jun 5.

PMID:
16753258
40.

Decrease in salivary secretion by radiation mediated by nitric oxide and prostaglandins.

de la Cal C, Lomniczi A, Mohn CE, De Laurentiis A, Casal M, Chiarenza A, Paz D, McCann SM, Rettori V, Elverdín JC.

Neuroimmunomodulation. 2006;13(1):19-27. Epub 2006 May 10.

PMID:
16691037
41.

Neuroendocrine mechanisms controlling female puberty: new approaches, new concepts.

Ojeda SR, Roth C, Mungenast A, Heger S, Mastronardi C, Parent AS, Lomniczi A, Jung H.

Int J Androl. 2006 Feb;29(1):256-63; discussion 286-90. Review.

43.

Minireview: the neuroendocrine regulation of puberty: is the time ripe for a systems biology approach?

Ojeda SR, Lomniczi A, Mastronardi C, Heger S, Roth C, Parent AS, Matagne V, Mungenast AE.

Endocrinology. 2006 Mar;147(3):1166-74. Epub 2005 Dec 22. Review.

44.

erbB-1 and erbB-4 receptors act in concert to facilitate female sexual development and mature reproductive function.

Prevot V, Lomniczi A, Corfas G, Ojeda SR.

Endocrinology. 2005 Mar;146(3):1465-72. Epub 2004 Dec 9.

PMID:
15591145
45.

The neurobiology of female puberty.

Ojeda SR, Prevot V, Heger S, Lomniczi A, Dziedzic B, Mungenast A.

Horm Res. 2003;60 Suppl 3:15-20. Review.

PMID:
14671391
46.

Glia-to-neuron signaling and the neuroendocrine control of female puberty.

Ojeda SR, Prevot V, Heger S, Lomniczi A, Dziedzic B, Mungenast A.

Ann Med. 2003;35(4):244-55. Review.

PMID:
12846266
47.

Interaction among beta-endorphin, nitric oxide and prostaglandins during ovulation in rats.

Faletti AG, Mohn C, Farina M, Lomniczi A, Rettori V.

Reproduction. 2003 Apr;125(4):469-77.

PMID:
12683918
48.
49.

Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes.

Prevot V, Rio C, Cho GJ, Lomniczi A, Heger S, Neville CM, Rosenthal NA, Ojeda SR, Corfas G.

J Neurosci. 2003 Jan 1;23(1):230-9.

50.

Mechanisms of inhibition of LHRH release by alcohol and cannabinoids.

Rettori V, Lomniczi A, Mohn C, Scorticati C, Vissio P, Lasaga M, Franchi A, McCann SM.

Prog Brain Res. 2002;141:175-81. Review. No abstract available.

PMID:
12508569

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