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Items: 1 to 50 of 101

1.

TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.

Ottaviani S, Stebbing J, Frampton AE, Zagorac S, Krell J, de Giorgio A, Trabulo SM, Nguyen VTM, Magnani L, Feng H, Giovannetti E, Funel N, Gress TM, Jiao LR, Lombardo Y, Lemoine NR, Heeschen C, Castellano L.

Nat Commun. 2018 May 10;9(1):1845. doi: 10.1038/s41467-018-03962-x.

2.
3.

Dietary soya protein improves intra-myocardial lipid deposition and altered glucose metabolism in a hypertensive, dyslipidaemic, insulin-resistant rat model.

Oliva ME, Creus A, Ferreira MR, Chicco A, Lombardo YB.

Br J Nutr. 2018 Jan;119(2):131-142. doi: 10.1017/S000711451700321X. Epub 2017 Dec 22.

PMID:
29268800
4.

Dietary Salba (Salvia hispanica L) improves the altered metabolic fate of glucose and reduces increased collagen deposition in the heart of insulin-resistant rats.

Creus A, Benmelej A, Villafañe N, Lombardo YB.

Prostaglandins Leukot Essent Fatty Acids. 2017 Jun;121:30-39. doi: 10.1016/j.plefa.2017.06.002. Epub 2017 Jun 5.

PMID:
28651695
5.

Correction: MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.

Melaiu O, Stebbing J, Lombardo Y, Bracci E, Uehara N, Bonotti A, Cristaudo A, Foddis R, Mutti L, Barale R, Gemignani F, Giamas G, Landi S.

PLoS One. 2017 Jun 22;12(6):e0180317. doi: 10.1371/journal.pone.0180317. eCollection 2017.

6.

Dietary soy protein improves adipose tissue dysfunction by modulating parameters related with oxidative stress in dyslipidemic insulin-resistant rats.

Illesca PG, Álvarez SM, Selenscig DA, Ferreira MDR, Giménez MS, Lombardo YB, D'Alessandro ME.

Biomed Pharmacother. 2017 Apr;88:1008-1015. doi: 10.1016/j.biopha.2017.01.153. Epub 2017 Feb 6.

PMID:
28178612
7.

Could post-weaning dietary chia seed mitigate the development of dyslipidemia, liver steatosis and altered glucose homeostasis in offspring exposed to a sucrose-rich diet from utero to adulthood?

Fortino MA, Oliva ME, Rodriguez S, Lombardo YB, Chicco A.

Prostaglandins Leukot Essent Fatty Acids. 2017 Jan;116:19-26. doi: 10.1016/j.plefa.2016.11.003. Epub 2016 Dec 6.

PMID:
28088290
8.
10.

Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion.

Nguyen VT, Barozzi I, Faronato M, Lombardo Y, Steel JH, Patel N, Darbre P, Castellano L, Győrffy B, Woodley L, Meira A, Patten DK, Vircillo V, Periyasamy M, Ali S, Frige G, Minucci S, Coombes RC, Magnani L.

Nat Commun. 2015 Nov 27;6:10044. doi: 10.1038/ncomms10044.

11.

Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer.

Lin ML, Patel H, Remenyi J, Banerji CR, Lai CF, Periyasamy M, Lombardo Y, Busonero C, Ottaviani S, Passey A, Quinlan PR, Purdie CA, Jordan LB, Thompson AM, Finn RS, Rueda OM, Caldas C, Gil J, Coombes RC, Fuller-Pace FV, Teschendorff AE, Buluwela L, Ali S.

Oncotarget. 2015 Aug 28;6(25):21685-703.

12.

The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer.

Magnani L, Patten DK, Nguyen VT, Hong SP, Steel JH, Patel N, Lombardo Y, Faronato M, Gomes AR, Woodley L, Page K, Guttery D, Primrose L, Fernandez Garcia D, Shaw J, Viola P, Green A, Nolan C, Ellis IO, Rakha EA, Shousha S, Lam EW, Győrffy B, Lupien M, Coombes RC.

Oncotarget. 2015 Sep 8;6(26):21878-91.

13.

DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation.

Faronato M, Nguyen VT, Patten DK, Lombardo Y, Steel JH, Patel N, Woodley L, Shousha S, Pruneri G, Coombes RC, Magnani L.

Oncotarget. 2015 Sep 8;6(26):22467-79.

14.

Mammosphere formation assay from human breast cancer tissues and cell lines.

Lombardo Y, de Giorgio A, Coombes CR, Stebbing J, Castellano L.

J Vis Exp. 2015 Mar 22;(97). doi: 10.3791/52671.

15.

Time course of adipose tissue dysfunction associated with antioxidant defense, inflammatory cytokines and oxidative stress in dyslipemic insulin resistant rats.

D'Alessandro ME, Selenscig D, Illesca P, Chicco A, Lombardo YB.

Food Funct. 2015 Apr;6(4):1299-309. doi: 10.1039/c4fo00903g.

PMID:
25765549
16.

Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells.

Filipović A, Lombardo Y, Faronato M, Abrahams J, Aboagye E, Nguyen QD, d'Aqua BB, Ridley A, Green A, Rahka E, Ellis I, Recchi C, Przulj N, Sarajlić A, Alattia JR, Fraering P, Deonarain M, Coombes RC.

Breast Cancer Res Treat. 2014 Nov;148(2):455-62. doi: 10.1007/s10549-014-3119-z. Epub 2014 Sep 24. Erratum in: Breast Cancer Res Treat. 2014 Nov;148(2):463. Fronato, Monica [corrected to Faronato, Monica].

17.

The kinase LMTK3 promotes invasion in breast cancer through GRB2-mediated induction of integrin β₁.

Xu Y, Zhang H, Lit LC, Grothey A, Athanasiadou M, Kiritsi M, Lombardo Y, Frampton AE, Green AR, Ellis IO, Ali S, Lenz HJ, Thanou M, Stebbing J, Giamas G.

Sci Signal. 2014 Jun 17;7(330):ra58. doi: 10.1126/scisignal.2005170.

PMID:
24939894
18.

Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells.

Lombardo Y, Faronato M, Filipovic A, Vircillo V, Magnani L, Coombes RC.

Breast Cancer Res. 2014 Jun 11;16(3):R62. doi: 10.1186/bcr3675.

19.

KSR1 regulates BRCA1 degradation and inhibits breast cancer growth.

Stebbing J, Zhang H, Xu Y, Lit LC, Green AR, Grothey A, Lombardo Y, Periyasamy M, Blighe K, Zhang W, Shaw JA, Ellis IO, Lenz HJ, Giamas G.

Oncogene. 2015 Apr 16;34(16):2103-14. doi: 10.1038/onc.2014.129. Epub 2014 Jun 9.

PMID:
24909178
20.

Mechanisms underlying the beneficial effect of soy protein in improving the metabolic abnormalities in the liver and skeletal muscle of dyslipemic insulin resistant rats.

Oliva ME, Chicco A, Lombardo YB.

Eur J Nutr. 2015 Apr;54(3):407-19. doi: 10.1007/s00394-014-0721-0. Epub 2014 Jun 5.

PMID:
24898793
21.

MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.

Melaiu O, Stebbing J, Lombardo Y, Bracci E, Uehara N, Bonotti A, Cristaudo A, Foddis R, Mutti L, Barale R, Gemignani F, Giamas G, Landi S.

PLoS One. 2014 Jan 21;9(1):e85935. doi: 10.1371/journal.pone.0085935. eCollection 2014. Erratum in: PLoS One. 2017 Jun 22;12 (6):e0180317.

22.

The miR-106b~25 cluster promotes bypass of doxorubicin-induced senescence and increase in motility and invasion by targeting the E-cadherin transcriptional activator EP300.

Zhou Y, Hu Y, Yang M, Jat P, Li K, Lombardo Y, Xiong D, Coombes RC, Raguz S, Yagüe E.

Cell Death Differ. 2014 Mar;21(3):462-74. doi: 10.1038/cdd.2013.167. Epub 2013 Nov 22.

23.

Dietary Salba (Salvia hispanica L) seed rich in α-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats.

Oliva ME, Ferreira MR, Chicco A, Lombardo YB.

Prostaglandins Leukot Essent Fatty Acids. 2013 Oct;89(5):279-89. doi: 10.1016/j.plefa.2013.09.010. Epub 2013 Sep 25.

PMID:
24120122
24.
25.

Changes in hepatic lipogenic and oxidative enzymes and glucose homeostasis induced by an acetyl-L-carnitine and nicotinamide treatment in dyslipidaemic insulin-resistant rats.

Ferreira MR, Camberos Mdel C, Selenscig D, Martucci LC, Chicco A, Lombardo YB, Cresto JC.

Clin Exp Pharmacol Physiol. 2013 Mar;40(3):205-11. doi: 10.1111/1440-1681.12050.

PMID:
23278446
26.

Fish oil reverses the altered glucose transporter, phosphorylation, insulin receptor substrate-1 protein level and lipid contents in the skeletal muscle of sucrose-rich diet fed rats.

D'Alessandro ME, Chicco A, Lombardo YB.

Prostaglandins Leukot Essent Fatty Acids. 2013 Feb;88(2):171-7. doi: 10.1016/j.plefa.2012.11.003. Epub 2012 Dec 1.

PMID:
23206329
27.

Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo.

Lombardo Y, Filipović A, Molyneux G, Periyasamy M, Giamas G, Hu Y, Trivedi PS, Wang J, Yagüe E, Michel L, Coombes RC.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16558-63. doi: 10.1073/pnas.1206268109. Epub 2012 Sep 24.

28.

Dietary chia seed induced changes in hepatic transcription factors and their target lipogenic and oxidative enzyme activities in dyslipidaemic insulin-resistant rats.

Rossi AS, Oliva ME, Ferreira MR, Chicco A, Lombardo YB.

Br J Nutr. 2013 May;109(9):1617-27. doi: 10.1017/S0007114512003558. Epub 2012 Sep 5.

PMID:
22947172
29.

Sucrose-rich feeding during rat pregnancy-lactation and/or after weaning alters glucose and lipid metabolism in adult offspring.

D'Alessandro ME, Oliva ME, Ferreira MR, Selenscig D, Lombardo YB, Chicco A.

Clin Exp Pharmacol Physiol. 2012 Jul;39(7):623-9. doi: 10.1111/j.1440-1681.2012.05720.x.

PMID:
22612392
30.

Fish oil normalizes plasma glucose levels and improves liver carbohydrate metabolism in rats fed a sucrose-rich diet.

Hein GJ, Chicco A, Lombardo YB.

Lipids. 2012 Feb;47(2):141-50. doi: 10.1007/s11745-011-3623-4. Epub 2011 Nov 2.

PMID:
22045300
31.

Soya protein ameliorates the metabolic abnormalities of dysfunctional adipose tissue of dyslipidaemic rats fed a sucrose-rich diet.

Oliva ME, Selenscig D, D'Alessandro ME, Chicco A, Lombardo YB.

Br J Nutr. 2011 Apr;105(8):1188-98. doi: 10.1017/S0007114510004915. Epub 2010 Dec 1.

PMID:
21118606
32.

β-Cell adaptation/dysfunction in an animal model of dyslipidemia and insulin resistance induced by the chronic administration of a sucrose-rich diet.

Ferreira Mdel R, Lombardo YB, Chicco A.

Islets. 2010 Nov-Dec;2(6):367-73. doi: 10.4161/isl.2.6.13869. Epub 2010 Nov 1.

PMID:
21099338
33.

Is Lipotoxicity presents in the early stages of an experimental model of autoimmune diabetes? Further studies in the multiple low dose of streptozotocin model.

Karabatas L, Oliva ME, Dascal E, Hein GJ, Pastorale C, Chicco A, Lombardo YB, Basabe JC.

Islets. 2010 May-Jun;2(3):190-9. doi: 10.4161/isl.2.3.11655.

PMID:
21099313
34.

Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.

Lombardo Y, Scopelliti A, Cammareri P, Todaro M, Iovino F, Ricci-Vitiani L, Gulotta G, Dieli F, de Maria R, Stassi G.

Gastroenterology. 2011 Jan;140(1):297-309. doi: 10.1053/j.gastro.2010.10.005. Epub 2010 Oct 14.

PMID:
20951698
35.

Survivin is regulated by interleukin-4 in colon cancer stem cells.

Di Stefano AB, Iovino F, Lombardo Y, Eterno V, Höger T, Dieli F, Stassi G, Todaro M.

J Cell Physiol. 2010 Nov;225(2):555-61. doi: 10.1002/jcp.22238.

PMID:
20506498
36.

Evidences of cervical cancer stem cells derived from established cell lines.

Todaro M, Lombardo Y, Stassi G.

Cell Cycle. 2010 Apr 1;9(7):1238-9. Epub 2010 Apr 1. No abstract available.

PMID:
20404528
37.

Increased leptin storage with altered leptin secretion from adipocytes of rats with sucrose-induced dyslipidemia and insulin resistance: effect of dietary fish oil.

Selenscig D, Rossi A, Chicco A, Lombardo YB.

Metabolism. 2010 Jun;59(6):787-95. doi: 10.1016/j.metabol.2009.09.025. Epub 2009 Dec 16.

PMID:
20005540
38.

Nuclear receptors and hepatic lipidogenic enzyme response to a dyslipidemic sucrose-rich diet and its reversal by fish oil n-3 polyunsaturated fatty acids.

Hein GJ, Bernasconi AM, Montanaro MA, Pellon-Maison M, Finarelli G, Chicco A, Lombardo YB, Brenner RR.

Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E429-39. doi: 10.1152/ajpendo.00513.2009. Epub 2009 Dec 1.

39.

Lipogenic enzyme activities and glucose uptake in fat tissue of dyslipemic, insulin-resistant rats: effects of fish oil.

Rossi AS, Lombardo YB, Chicco AG.

Nutrition. 2010 Feb;26(2):209-17. doi: 10.1016/j.nut.2009.04.006. Epub 2009 Aug 8.

PMID:
19665871
40.

Soya protein reverses dyslipidaemia and the altered capacity of insulin-stimulated glucose utilization in the skeletal muscle of sucrose-rich diet-fed rats.

Oliva ME, Chicco AG, Lombardo YB.

Br J Nutr. 2009 Jul;102(1):60-8. doi: 10.1017/S0007114508159013. Epub 2008 Dec 15.

PMID:
19079840
41.

Dietary fish oil reverses lipotoxicity, altered glucose metabolism, and nPKCepsilon translocation in the heart of dyslipemic insulin-resistant rats.

D'Alessandro ME, Chicco A, Lombardo YB.

Metabolism. 2008 Jul;57(7):911-9. doi: 10.1016/j.metabol.2008.02.005.

PMID:
18555831
42.

Crucial role of interleukin-4 in the survival of colon cancer stem cells.

Francipane MG, Alea MP, Lombardo Y, Todaro M, Medema JP, Stassi G.

Cancer Res. 2008 Jun 1;68(11):4022-5. doi: 10.1158/0008-5472.CAN-07-6874. Review.

43.

Dietary chia seed (Salvia hispanica L.) rich in alpha-linolenic acid improves adiposity and normalises hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats.

Chicco AG, D'Alessandro ME, Hein GJ, Oliva ME, Lombardo YB.

Br J Nutr. 2009 Jan;101(1):41-50. doi: 10.1017/S000711450899053X. Epub 2008 May 20.

PMID:
18492301
44.

Isolation and culture of colon cancer stem cells.

Cammareri P, Lombardo Y, Francipane MG, Bonventre S, Todaro M, Stassi G.

Methods Cell Biol. 2008;86:311-24. doi: 10.1016/S0091-679X(08)00014-9.

PMID:
18442654
45.

Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4.

Todaro M, Lombardo Y, Francipane MG, Alea MP, Cammareri P, Iovino F, Di Stefano AB, Di Bernardo C, Agrusa A, Condorelli G, Walczak H, Stassi G.

Cell Death Differ. 2008 Apr;15(4):762-72. doi: 10.1038/sj.cdd.4402305. Epub 2008 Jan 18.

46.
47.

MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells.

Siragusa M, Zerilli M, Iovino F, Francipane MG, Lombardo Y, Ricci-Vitiani L, Di Gesù G, Todaro M, De Maria R, Stassi G.

Cancer Res. 2007 Jun 1;67(11):5522-30. Erratum in: Cancer Res. 2018 Jul 15;78(14):4101. Cancer Res. 2018 Nov 1;78(21):6344.

48.

Metabolic syndrome: effects of n-3 PUFAs on a model of dyslipidemia, insulin resistance and adiposity.

Lombardo YB, Hein G, Chicco A.

Lipids. 2007 May;42(5):427-37. Epub 2007 Mar 17.

PMID:
17476547
49.

Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. A review.

Lombardo YB, Chicco AG.

J Nutr Biochem. 2006 Jan;17(1):1-13. Epub 2005 Sep 8. Review.

PMID:
16214332
50.

Dietary fish oil positively regulates plasma leptin and adiponectin levels in sucrose-fed, insulin-resistant rats.

Rossi AS, Lombardo YB, Lacorte JM, Chicco AG, Rouault C, Slama G, Rizkalla SW.

Am J Physiol Regul Integr Comp Physiol. 2005 Aug;289(2):R486-R494.

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