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Plasma pNfH levels differentiate SBMA from ALS.

Lombardi V, Bombaci A, Zampedri L, Lu CH, Malik B, Zetterberg H, Heslegrave AJ, Rinaldi C, Greensmith L, Hanna MG, Malaspina A, Fratta P.

J Neurol Neurosurg Psychiatry. 2019 Oct 1. pii: jnnp-2019-320624. doi: 10.1136/jnnp-2019-320624. [Epub ahead of print] No abstract available.


Low temperature traps myosin motors of mammalian muscle in a refractory state that prevents activation.

Caremani M, Brunello E, Linari M, Fusi L, Irving TC, Gore D, Piazzesi G, Irving M, Lombardi V, Reconditi M.

J Gen Physiol. 2019 Sep 25. pii: jgp.201912424. doi: 10.1085/jgp.201912424. [Epub ahead of print]


Neurofilaments in pre-symptomatic ALS and the impact of genotype.

Benatar M, Wuu J, Lombardi V, Jeromin A, Bowser R, Andersen PM, Malaspina A.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 Nov;20(7-8):538-548. doi: 10.1080/21678421.2019.1646769. Epub 2019 Aug 21.


Safety and tolerability of Triumeq in amyotrophic lateral sclerosis: the Lighthouse trial.

Gold J, Rowe DB, Kiernan MC, Vucic S, Mathers S, van Eijk RPA, Nath A, Garcia Montojo M, Norato G, Santamaria UA, Rogers ML, Malaspina A, Lombardi V, Mehta PR, Westeneng HJ, van den Berg LH, Al-Chalabi A.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 Nov;20(7-8):595-604. doi: 10.1080/21678421.2019.1632899. Epub 2019 Jul 8.


Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral Sclerosis.

Leoni E, Bremang M, Mitra V, Zubiri I, Jung S, Lu CH, Adiutori R, Lombardi V, Russell C, Koncarevic S, Ward M, Pike I, Malaspina A.

Sci Rep. 2019 Mar 14;9(1):4478. doi: 10.1038/s41598-019-40632-4.


Thick Filament Length Changes in Muscle Have Both Elastic and Structural Components.

Reconditi M, Fusi L, Caremani M, Brunello E, Linari M, Piazzesi G, Lombardi V, Irving M.

Biophys J. 2019 Mar 19;116(6):983-984. doi: 10.1016/j.bpj.2019.02.009. Epub 2019 Mar 2. No abstract available.


IL-10 mRNA levels in whole blood cells correlate with house dust mite allergen immunotherapy efficacy.

Guéguen C, Luce S, Lombardi V, Baron-Bodo V, Moingeon P, Mascarell L.

Allergy. 2019 Feb 21. doi: 10.1111/all.13751. [Epub ahead of print] No abstract available.


Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy.

Lombardi V, Querin G, Ziff OJ, Zampedri L, Martinelli I, Heller C, Foiani M, Bertolin C, Lu CH, Malik B, Allen K, Rinaldi C, Zetterberg H, Heslegrave A, Greensmith L, Hanna M, Soraru G, Malaspina A, Fratta P.

Neurology. 2019 Mar 12;92(11):e1205-e1211. doi: 10.1212/WNL.0000000000007097. Epub 2019 Feb 20.


Sociodemographic, clinical and criminological characteristics of a sample of Italian Volterra REMS patients.

Lombardi V, Veltri A, Montanelli C, Mundo F, Restuccia G, Cesari D, Maccari M, Scarpa F, Sbrana A.

Int J Law Psychiatry. 2019 Jan - Feb;62:50-55. doi: 10.1016/j.ijlp.2018.09.009. Epub 2018 Nov 26.


Inotropic interventions do not change the resting state of myosin motors during cardiac diastole.

Caremani M, Pinzauti F, Powers JD, Governali S, Narayanan T, Stienen GJM, Reconditi M, Linari M, Lombardi V, Piazzesi G.

J Gen Physiol. 2019 Jan 7;151(1):53-65. doi: 10.1085/jgp.201812196. Epub 2018 Dec 3.


CCR10+ ILC2s with ILC1-like properties exhibit a protective function in severe allergic asthma.

Beuraud C, Lombardi V, Luce S, Horiot S, Naline E, Neukirch C, Airouche S, Perchet T, Golub R, Devillier P, Chollet-Martin S, Baron-Bodo V, Nony E, Aubier M, Mascarell L, Moingeon P.

Allergy. 2019 May;74(5):933-943. doi: 10.1111/all.13679. Epub 2018 Dec 28.


Evaluation of four clinical laboratory parameters for the diagnosis of myalgic encephalomyelitis.

De Meirleir KL, Mijatovic T, Subramanian K, Schlauch KA, Lombardi VC.

J Transl Med. 2018 Nov 21;16(1):322. doi: 10.1186/s12967-018-1696-z.


Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis.

Zubiri I, Lombardi V, Bremang M, Mitra V, Nardo G, Adiutori R, Lu CH, Leoni E, Yip P, Yildiz O, Ward M, Greensmith L, Bendotti C, Pike I, Malaspina A.

Mol Neurodegener. 2018 Nov 7;13(1):60. doi: 10.1186/s13024-018-0292-2.


A myosin II nanomachine mimicking the striated muscle.

Pertici I, Bongini L, Melli L, Bianchi G, Salvi L, Falorsi G, Squarci C, Bozó T, Cojoc D, Kellermayer MSZ, Lombardi V, Bianco P.

Nat Commun. 2018 Aug 30;9(1):3532. doi: 10.1038/s41467-018-06073-9.


Single-nucleotide polymorphisms in a cohort of significantly obese women without cardiometabolic diseases.

Schlauch KA, Kulick D, Subramanian K, De Meirleir KL, Palotás A, Lombardi VC.

Int J Obes (Lond). 2019 Feb;43(2):253-262. doi: 10.1038/s41366-018-0181-3. Epub 2018 Aug 17.


Neurofilament light: A candidate biomarker of presymptomatic amyotrophic lateral sclerosis and phenoconversion.

Benatar M, Wuu J, Andersen PM, Lombardi V, Malaspina A.

Ann Neurol. 2018 Jul;84(1):130-139. doi: 10.1002/ana.25276. Epub 2018 Aug 16.


Thick Filament Mechano-Sensing in Skeletal and Cardiac Muscles: A Common Mechanism Able to Adapt the Energetic Cost of the Contraction to the Task.

Piazzesi G, Caremani M, Linari M, Reconditi M, Lombardi V.

Front Physiol. 2018 Jun 14;9:736. doi: 10.3389/fphys.2018.00736. eCollection 2018.


Nutritional modulation of the intestinal microbiota; future opportunities for the prevention and treatment of neuroimmune and neuroinflammatory disease.

Lombardi VC, De Meirleir KL, Subramanian K, Nourani SM, Dagda RK, Delaney SL, Palotás A.

J Nutr Biochem. 2018 Nov;61:1-16. doi: 10.1016/j.jnutbio.2018.04.004. Epub 2018 Apr 19. Review.


The force and stiffness of myosin motors in the isometric twitch of a cardiac trabecula and the effect of the extracellular calcium concentration.

Pinzauti F, Pertici I, Reconditi M, Narayanan T, Stienen GJM, Piazzesi G, Lombardi V, Linari M, Caremani M.

J Physiol. 2018 Jul;596(13):2581-2596. doi: 10.1113/JP275579. Epub 2018 May 27.


In vitro and in vivo cytotoxic effect of AntiGan against tumor cells.

Lombardi VRM, Carrera I, Cacabelos R.

Exp Ther Med. 2018 Mar;15(3):2547-2556. doi: 10.3892/etm.2017.5681. Epub 2017 Dec 27.


Role of bioactive lipofishins in prevention of inflammation and colon cancer.

Lombardi VRM, Carrera I, Corzo L, Cacabelos R.

Semin Cancer Biol. 2019 Jun;56:175-184. doi: 10.1016/j.semcancer.2017.11.012. Epub 2017 Nov 24. Review.


Serum Cytokine Profiles Differentiating Hemorrhagic Fever with Renal Syndrome and Hantavirus Pulmonary Syndrome.

Khaiboullina SF, Levis S, Morzunov SP, Martynova EV, Anokhin VA, Gusev OA, St Jeor SC, Lombardi VC, Rizvanov AA.

Front Immunol. 2017 May 18;8:567. doi: 10.3389/fimmu.2017.00567. eCollection 2017.


Effector and regulatory dendritic cells display distinct patterns of miRNA expression.

Lombardi V, Luce S, Moussu H, Morizur L, Gueguen C, Neukirch C, Chollet-Martin S, Mascarell L, Aubier M, Baron-Bodo V, Moingeon P.

Immun Inflamm Dis. 2017 Sep;5(3):310-317. doi: 10.1002/iid3.165. Epub 2017 May 12.


Physical performance in newly diagnosed hypothyroidism: a pilot study.

Gallo D, Piantanida E, Veronesi G, Lai A, Sassi L, Lombardi V, Masiello E, Premoli P, Bianconi E, Cusini C, Rosetti S, Tanda ML, Toniolo A, Ferrario M, Bartalena L.

J Endocrinol Invest. 2017 Oct;40(10):1099-1106. doi: 10.1007/s40618-017-0661-7. Epub 2017 Apr 22.


In Vitro Screening for Cytotoxic Activity of Herbal Extracts.

Lombardi VR, Carrera I, Cacabelos R.

Evid Based Complement Alternat Med. 2017;2017:2675631. doi: 10.1155/2017/2675631. Epub 2017 Mar 13.


Comparative Assessment of Cytokine Pattern in Early and Late Onset of Neonatal Sepsis.

Khaertynov KS, Boichuk SV, Khaiboullina SF, Anokhin VA, Andreeva AA, Lombardi VC, Satrutdinov MA, Agafonova EA, Rizvanov AA.

J Immunol Res. 2017;2017:8601063. doi: 10.1155/2017/8601063. Epub 2017 Mar 5.


Myosin filament activation in the heart is tuned to the mechanical task.

Reconditi M, Caremani M, Pinzauti F, Powers JD, Narayanan T, Stienen GJ, Linari M, Lombardi V, Piazzesi G.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3240-3245. doi: 10.1073/pnas.1619484114. Epub 2017 Mar 6.


The Skin-Brain Connection Hypothesis, Bringing Together CCL27-Mediated T-Cell Activation in the Skin and Neural Cell Damage in the Adult Brain.

Blatt NL, Khaiboullin TI, Lombardi VC, Rizvanov AA, Khaiboullina SF.

Front Immunol. 2017 Jan 16;7:683. doi: 10.3389/fimmu.2016.00683. eCollection 2016.


Relationship quality of persons with obstructive sleep apnoea syndrome.

Tramonti F, Maestri M, Carnicelli L, Fava G, Lombardi V, Rossi M, Fabbrini M, Di Coscio E, Iacopini E, Bonanni E.

Psychol Health Med. 2017 Sep;22(8):896-901. doi: 10.1080/13548506.2017.1281973. Epub 2017 Jan 19.


Enhancing Allergen-Presentation Platforms for Sublingual Immunotherapy.

Moingeon P, Lombardi V, Baron-Bodo V, Mascarell L.

J Allergy Clin Immunol Pract. 2017 Jan - Feb;5(1):23-31. doi: 10.1016/j.jaip.2016.07.020. Review.


Previously Unidentified Single Nucleotide Polymorphisms in HIV/AIDS Cases Associate with Clinical Parameters and Disease Progression.

Anokhin VV, Bakhteeva LB, Khasanova GR, Khaiboullina SF, Martynova EV, Tillett RL, Schlauch KA, Lombardi VC, Rizvanov AA.

Biomed Res Int. 2016;2016:2742648. doi: 10.1155/2016/2742648. Epub 2016 Dec 5.


Serum Cytokine Signature That Discriminates Helicobacter pylori Positive and Negative Juvenile Gastroduodenitis.

Khaiboullina SF, Abdulkhakov S, Khalikova A, Safina D, Martynova EV, Davidyuk Y, Khuzin F, Faizullina R, Lombardi VC, Cherepnev GV, Rizvanov AA.

Front Microbiol. 2016 Dec 15;7:1916. doi: 10.3389/fmicb.2016.01916. eCollection 2016.


Humoral Immunity Profiling of Subjects with Myalgic Encephalomyelitis Using a Random Peptide Microarray Differentiates Cases from Controls with High Specificity and Sensitivity.

Singh S, Stafford P, Schlauch KA, Tillett RR, Gollery M, Johnston SA, Khaiboullina SF, De Meirleir KL, Rawat S, Mijatovic T, Subramanian K, Palotás A, Lombardi VC.

Mol Neurobiol. 2018 Jan;55(1):633-641. doi: 10.1007/s12035-016-0334-0. Epub 2016 Dec 15.


Sialylated Fetuin-A as a candidate predictive biomarker for successful grass pollen allergen immunotherapy.

Caillot N, Bouley J, Jain K, Mariano S, Luce S, Horiot S, Airouche S, Beuraud C, Beauvallet C, Devillier P, Chollet-Martin S, Kellenberger C, Mascarell L, Chabre H, Batard T, Nony E, Lombardi V, Baron-Bodo V, Moingeon P.

J Allergy Clin Immunol. 2017 Sep;140(3):759-770.e13. doi: 10.1016/j.jaci.2016.10.036. Epub 2016 Dec 10.


Transcriptional Analysis of Blood Lymphocytes and Skin Fibroblasts, Keratinocytes, and Endothelial Cells as a Potential Biomarker for Alzheimer's Disease.

Mukhamedyarov MA, Rizvanov AA, Yakupov EZ, Zefirov AL, Kiyasov AP, Reis HJ, Teixeira AL, Vieira LB, Lima LM, Salafutdinov II, Petukhova EO, Khaiboullina SF, Schlauch KA, Lombardi VC, Palotás A.

J Alzheimers Dis. 2016 Oct 18;54(4):1373-1383.


Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle.

Fusi L, Percario V, Brunello E, Caremani M, Bianco P, Powers JD, Reconditi M, Lombardi V, Piazzesi G.

J Physiol. 2017 Feb 15;595(4):1127-1142. doi: 10.1113/JP273299. Epub 2016 Dec 12.


Protein kinase Cθ controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen.

Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, Ledru A, Gallerand M, Lombardi V, Mascarell L, Marquant Q, Apetoh L, Erard F, Le Bert M, Trovero F, Quesniaux VFJ, Ryffel B, Togbe D.

J Allergy Clin Immunol. 2017 May;139(5):1650-1666. doi: 10.1016/j.jaci.2016.08.044. Epub 2016 Oct 14.


Is muscle powered by springs or motors?

Bianco P, Reconditi M, Piazzesi G, Lombardi V.

J Muscle Res Cell Motil. 2016 Oct;37(4-5):165-167. Review. No abstract available.


Hantavirus Infection Suppresses Thrombospondin-1 Expression in Cultured Endothelial Cells in a Strain-Specific Manner.

Khaiboullina SF, Morzunov SP, St Jeor SC, Rizvanov AA, Lombardi VC.

Front Microbiol. 2016 Jul 19;7:1077. doi: 10.3389/fmicb.2016.01077. eCollection 2016.


An AT-barrier mechanically controls DNA reannealing under tension.

Bongini L, Pongor C, Falorsi G, Pertici I, Kellermayer M, Lombardi V, Bianco P.

Nucleic Acids Res. 2016 Sep 19;44(16):7954-62. doi: 10.1093/nar/gkw604. Epub 2016 Jul 4.


Ethyl-2-amino-pyrrole-3-carboxylates are novel potent anticancer agents that affect tubulin polymerization, induce G2/M cell-cycle arrest, and effectively inhibit soft tissue cancer cell growth in vitro.

Boichuk S, Galembikova A, Zykova S, Ramazanov B, Khusnutdinov R, Dunaev P, Khaibullina S, Lombardi V.

Anticancer Drugs. 2016 Aug;27(7):620-34. doi: 10.1097/CAD.0000000000000372.


Size and speed of the working stroke of cardiac myosin in situ.

Caremani M, Pinzauti F, Reconditi M, Piazzesi G, Stienen GJ, Lombardi V, Linari M.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3675-80. doi: 10.1073/pnas.1525057113. Epub 2016 Mar 16.


Circulating innate lymphoid cells are differentially regulated in allergic and nonallergic subjects.

Lombardi V, Beuraud C, Neukirch C, Moussu H, Morizur L, Horiot S, Luce S, Wambre E, Linsley P, Chollet-Martin S, Baron-Bodo V, Aubier M, Moingeon P.

J Allergy Clin Immunol. 2016 Jul;138(1):305-308. doi: 10.1016/j.jaci.2015.12.1325. Epub 2016 Mar 4. No abstract available.


Decreased Numbers of CD57+CD3- Cells Identify Potential Innate Immune Differences in Patients with Autism Spectrum Disorder.

Siniscalco D, Mijatovic T, Bosmans E, Cirillo A, Kruzliak P, Lombardi VC, De Meirleir K, Antonucci N.

In Vivo. 2016 Mar-Apr;30(2):83-9.


Large-scale bioprospecting of cyanobacteria, micro- and macroalgae from the Aegean Sea.

Montalvão S, Demirel Z, Devi P, Lombardi V, Hongisto V, Perälä M, Hattara J, Imamoglu E, Tilvi SS, Turan G, Dalay MC, Tammela P.

N Biotechnol. 2016 May 25;33(3):399-406. doi: 10.1016/j.nbt.2016.02.002. Epub 2016 Feb 21.


Genome-wide association analysis identifies genetic variations in subjects with myalgic encephalomyelitis/chronic fatigue syndrome.

Schlauch KA, Khaiboullina SF, De Meirleir KL, Rawat S, Petereit J, Rizvanov AA, Blatt N, Mijatovic T, Kulick D, Palotás A, Lombardi VC.

Transl Psychiatry. 2016 Feb 9;6:e730. doi: 10.1038/tp.2015.208.


Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments.

Linari M, Brunello E, Reconditi M, Fusi L, Caremani M, Narayanan T, Piazzesi G, Lombardi V, Irving M.

Nature. 2015 Dec 10;528(7581):276-9. doi: 10.1038/nature15727. Epub 2015 Nov 11.


Changes in markers associated with dendritic cells driving the differentiation of either TH2 cells or regulatory T cells correlate with clinical benefit during allergen immunotherapy.

Gueguen C, Bouley J, Moussu H, Luce S, Duchateau M, Chamot-Rooke J, Pallardy M, Lombardi V, Nony E, Baron-Bodo V, Mascarell L, Moingeon P.

J Allergy Clin Immunol. 2016 Feb;137(2):545-58. doi: 10.1016/j.jaci.2015.09.015. Epub 2015 Oct 29.


Gut-Associated Plasmacytoid Dendritic Cells Display an Immature Phenotype and Upregulated Granzyme B in Subjects with HIV/AIDS.

Boichuk SV, Khaiboullina SF, Ramazanov BR, Khasanova GR, Ivanovskaya KA, Nizamutdinov EZ, Sharafutdinov MR, Martynova EV, DeMeirleir KL, Hulstaert J, Anokhin VA, Rizvanov AA, Lombardi VC.

Front Immunol. 2015 Sep 24;6:485. doi: 10.3389/fimmu.2015.00485. eCollection 2015.


Multiplex Analysis of Serum Cytokines in Humans with Hantavirus Pulmonary Syndrome.

Morzunov SP, Khaiboullina SF, St Jeor S, Rizvanov AA, Lombardi VC.

Front Immunol. 2015 Aug 31;6:432. doi: 10.3389/fimmu.2015.00432. eCollection 2015.

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